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https://www.readbyqxmd.com/read/28229607/therapeutic-impact-of-colon-capsule-endoscopy-with-pillcam%C3%A2-colon-2-after-incomplete-standard-colonoscopy-a-spanish-multicenter-study
#1
Óscar Nogales, Javier García-Lledó, Marisol Luján, David Nicolás, José Francisco Juanmartiñena, Begoña González-Suárez, Francisco Sánchez Ceballos, Ignacio Couto, José Olmedo, Cristina Garfia, Cristina Carretero, Ignacio Fernández Urién, Sarbelio Rodríguez, Matilde Asteinza, Pilar Olivencia, Ángeles Masedo, Miguel Muñoz-Navas, Beatriz Merino, Cecilia González Asanza
INTRODUCTION: Colon capsule endoscopy (CCE) is an alternative approach for the examination of the colon in patients who refuse colonoscopy or after incomplete colonoscopy (IC). We conducted a study to determine the frequency of complete colonoscopy after IC, the diagnostic yield of CCE, the therapeutic impact of lesions found in CCE, the level of colon cleanliness and the safety of the procedure. METHODS: We performed a prospective, multicenter study involving ten Spanish hospitals...
February 23, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28224451/pet-cta-detection-of-muscle-inflammation-related-to-cholesterol-crystal-emboli-without-arterial-obstruction
#2
M Hassan Pervaiz, Sridevi Durga, Abed Janoudi, Kevin Berger, George S Abela
BACKGROUND: PET/CTA was used to evaluate the effect of cholesterol crystal emboli (CCE) on muscle injury. Cholesterol crystals (CCs) released during plaque rupture travel downstream and lodge in muscle triggering inflammation and tissue injury. METHODS: Thigh muscles in three groups of rabbits (n = 22) were studied after intra-arterial injection of CCs, Group I (n = 10); polystyrene microspheres, Group II (n = 5); or normal saline, Group III (n = 7). After 48 hours, muscle inflammation and injury were measured by fluorodeoxy-glucose uptake using PET/CTA, serum tissue factor (TF), and creatinine phosphokinase (CPK)...
February 21, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28199333/comparative-and-functional-triatomine-genomics-reveals-reductions-and-expansions-in-insecticide-resistance-related-gene-families
#3
Lucila Traverso, Andrés Lavore, Ivana Sierra, Victorio Palacio, Jesús Martinez-Barnetche, José Manuel Latorre-Estivalis, Gaston Mougabure-Cueto, Flavio Francini, Marcelo G Lorenzo, Mario Henry Rodríguez, Sheila Ons, Rolando V Rivera-Pomar
BACKGROUND: Triatomine insects are vectors of Trypanosoma cruzi, a protozoan parasite that is the causative agent of Chagas' disease. This is a neglected disease affecting approximately 8 million people in Latin America. The existence of diverse pyrethroid resistant populations of at least two species demonstrates the potential of triatomines to develop high levels of insecticide resistance. Therefore, the incorporation of strategies for resistance management is a main concern for vector control programs...
February 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28196586/the-blue-light-dependent-phosphorylation-of-the-cce-domain-determines-the-photosensitivity-of-arabidopsis-cry2
#4
Qin Wang, William D Barshop, Mingdi Bian, Ajay A Vashisht, Reqing He, Xuhong Yu, Bin Liu, Paula Nguyen, Xuanming Liu, Xiaoying Zhao, James A Wohlschlegel, Chentao Lin
No abstract text is available yet for this article.
February 13, 2017: Molecular Plant
https://www.readbyqxmd.com/read/28167816/predictive-value-of-cumulative-blood-pressure-for-all-cause-mortality-and-cardiovascular-events
#5
Yan Xiu Wang, Lu Song, Ai Jun Xing, Ming Gao, Hai Yan Zhao, Chun Hui Li, Hua Ling Zhao, Shuo Hua Chen, Cheng Zhi Lu, Shou Ling Wu
The predictive value of cumulative blood pressure (BP) on all-cause mortality and cardiovascular and cerebrovascular events (CCE) has hardly been studied. In this prospective cohort study including 52,385 participants from the Kailuan Group who attended three medical examinations and without CCE, the impact of cumulative systolic BP (cumSBP) and cumulative diastolic BP (cumDBP) on all-cause mortality and CCEs was investigated. For the study population, the mean (standard deviation) age was 48.82 (11.77) years of which 40,141 (76...
February 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28166835/frequency-of-th17-cells-correlates-with-the-presence-of-lung-lesions-in-pigs-chronically-infected-with-actinobacillus-pleuropneumoniae
#6
Elena L Sassu, Andrea Ladinig, Stephanie C Talker, Maria Stadler, Christian Knecht, Heiko Stein, Janna Frömbling, Barbara Richter, Joachim Spergser, Monika Ehling-Schulz, Robert Graage, Isabel Hennig-Pauka, Wilhelm Gerner
Porcine contagious pleuropneumonia caused by Actinobacillus pleuropneumoniae (APP) remains one of the major causes of poor growth performance and respiratory disease in pig herds. While the role of antibodies against APP has been intensely studied, the porcine T cell response remains poorly characterized. To address this, pigs were intranasally infected with APP serotype 2 and euthanized during the acute phase [6-10 days post-infection (dpi)] or the chronic phase of APP infection (27-31 dpi). Lymphocytes isolated from blood, tonsils, lung tissue and tracheobronchial lymph nodes were analyzed by intracellular cytokine staining (ICS) for IL-17A, IL-10 and TNF-α production after in vitro stimulation with crude capsular extract (CCE) of the APP inoculation strain...
February 6, 2017: Veterinary Research
https://www.readbyqxmd.com/read/28138348/cholesterol-enrichment-impairs-capacitative-calcium-entry-enos-phosphorylation-shear-stress-induced-no-production
#7
Allison M Andrews, Tenderano T Muzorewa, Kelly A Zaccheo, Donald G Buerk, Dov Jaron, Kenneth A Barbee
Endothelial dysfunction, characterized by decreased production or availability of nitric oxide (NO), is widely believed to be the hallmark of early-stage atherosclerosis. In addition, hypercholesterolemia is considered a major risk factor for development of atherosclerosis and is associated with impaired flow-induced dilation. However, the mechanism by which elevated cholesterol levels leads to decreased production of NO is unclear. NO is released in response to shear stress and agonist-evoked changes in intracellular calcium...
February 2017: Cellular and Molecular Bioengineering
https://www.readbyqxmd.com/read/28063473/transfer-of-maternal-immunity-to-piglets-is-involved-in-early-protection-against-mycoplasma-hyosynoviae-infection
#8
K Tølbøll Lauritsen, T Hagedorn-Olsen, G Jungersen, U Riber, H Stryhn, N F Friis, P Lind, B Kristensen
Mycoplasma hyosynoviae causes arthritis in pigs older than 12 weeks. The role of colostrum in protection of piglets against M. hyosynoviae infection is not clear. Our objective was therefore to investigate whether transfer of maternal immunity to piglets was involved in early protection against the infection. Experimental infections were carried out in three groups of weaners receiving different levels of M. hyosynoviae-specific colostrum components; Group NC derived from Mycoplasma free sows and possessed no specific immunity to M...
January 2017: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/28048772/mo-de-207a-04-development-and-evaluation-of-an-adaptive-deformation-recovery-and-intensity-correction-adric-ct-reconstruction-technique
#9
Y Zhang, J Ma, J Wang
PURPOSE: Sequential same-patient CT images usually involve deformation-induced and non-deformation-induced voxel intensity changes. An adaptive deformation-recovery and intensity-correction (ADRIC) technique was developed to improve the CT reconstruction accuracy, and to separate deformation from non-deformation-induced voxel intensity changes between sequential CT images. METHODS: ADRIC views the new CT as a deformation of a prior high-quality CT volume, but with additional non-deformation-induced voxel intensity changes...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048111/su-f-j-38-dose-rates-and-preliminary-evaluation-of-contouring-similarity-metrics-using-4d-cone-beam-ct
#10
A Santoso, K Song, Y Qin, S Gardner, C Liu, R Cattaneo, I Chetty, B Movsas, M Aljouni, N Wen
PURPOSE: 4D imaging modalities require detailed characterization for clinical optimization. The On-Board Imager mounted on the linear accelerator was used to investigate dose rates in a tissue mimicking phantom using 4D-CBCT and assess variability of contouring similarity metrics between 4D-CT and 4D-CBCT retrospective reconstructions. METHODS: A 125 kVp thoracic protocol was used. A phantom placed on a motion platform simulated a patient's breathing cycle. An ion chamber was affixed inside the phantom's tissue mimicking cavities (i...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047636/su-f-t-566-absolute-film-dosimetry-for-stereotactic-radiosurgery-and-stereotactic-body-radiotherapy-quality-assurance-using-gafchromic-ebt3-films
#11
N Wen, S Lu, Y Qin, Y Huang, B Zhao, C Liu, I Chetty
PURPOSE: To evaluate the dosimetric uncertainty associated with Gafchromic (EBT3) films and establish an absolute dosimetry protocol for Stereotactic Radiosurgery (SRS) and Stereotactic Body Radiotherapy (SBRT). METHODS: EBT3 films were irradiated at each of seven different dose levels between 1 and 15 Gy with open fields, and standard deviations of dose maps were calculated at each color channel for evaluation. A scanner non-uniform response correction map was built by registering and comparing film doses to the reference diode array-based dose map delivered with the same doses...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047080/su-d-bra-03-analysis-of-systematic-errors-with-2d-3d-image-registration-for-target-localization-and-treatment-delivery-in-stereotactic-radiosurgery
#12
H Xu, I Chetty, N Wen
PURPOSE: Determine systematic deviations between 2D/3D and 3D/3D image registrations with six degrees of freedom (6DOF) for various imaging modalities and registration algorithms on the Varian Edge Linac. METHODS: The 6DOF systematic errors were assessed by comparing automated 2D/3D (kV/MV vs. CT) with 3D/3D (CBCT vs. CT) image registrations from different imaging pairs, CT slice thicknesses, couch angles, similarity measures, etc., using a Rando head and a pelvic phantom...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046890/su-f-j-177-a-novel-image-analysis-technique-center-pixel-method-to-quantify-end-to-end-tests
#13
N Wen, K Snyder, S Scheib, Y Qin, H Li, I Chetty
PURPOSE: To implement a novel image analysis technique, "center pixel method", to quantify end-to-end tests accuracy of a frameless, image guided stereotactic radiosurgery system. METHODS: The localization accuracy was determined by delivering radiation to an end-to-end prototype phantom. The phantom was scanned with 0.8 mm slice thickness. The treatment isocenter was placed at the center of the phantom. In the treatment room, CBCT images of the phantom (kVp=77, mAs=1022, slice thickness 1 mm) were acquired to register to the reference CT images...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046803/mo-ab-bra-09-development-and-evaluation-of-a-biomechanical-modeling-assisted-cbct-reconstruction-technique-bio-recon
#14
Y Zhang, J Nasehi Tehrani, J Wang
PURPOSE: To develop a Bio-recon technique by incorporating the biomechanical properties of anatomical structures into the deformation-based CBCT reconstruction process. METHODS: Bio-recon reconstructs the CBCT by deforming a prior high-quality CT/CBCT using a deformation-vector-field (DVF). The DVF is solved through two alternating steps: 2D-3D deformation and finite-element-analysis based biomechanical modeling. 2D-3D deformation optimizes the DVF through an 'intensity-driven' approach, which updates the DVF to minimize intensity mismatches between the acquired projections and the simulated projections from the deformed CBCT...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046671/mo-fg-campus-iep2-04-multiple-penalties-with-different-orders-for-structure-adaptive-cbct-reconstruction
#15
Q Shi, P Cheng, J Wang, S Tan, S Tan
PURPOSE: To combine total variation (TV) and Hessian penalty in a structure adaptive way for cone-beam CT (CBCT) reconstruction. METHODS: TV is a widely used first order penalty with good ability in suppressing noise and preserving edges but leads to the staircase effect in regions with smooth intensity transition. The second order Hessian penalty can effectively suppress the staircase effect with extra cost of blurring object edges. To take the best of both penalties we proposed a novel method to combine both for CBCT reconstruction in a structure adaptive way...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28028002/aqueous-outflow-a-continuum-from-trabecular-meshwork-to-episcleral-veins
#16
REVIEW
Teresia Carreon, Elizabeth van der Merwe, Ronald L Fellman, Murray Johnstone, Sanjoy K Bhattacharya
In glaucoma, lowered intraocular pressure (IOP) confers neuroprotection. Elevated IOP characterizes glaucoma and arises from impaired aqueous humor (AH) outflow. Increased resistance in the trabecular meshwork (TM), a filter-like structure essential to regulate AH outflow, may result in the impaired outflow. Flow through the 360° circumference of TM structures may be non-uniform, divided into high and low flow regions, termed as segmental. After flowing through the TM, AH enters Schlemm's canal (SC), which expresses both blood and lymphatic markers; AH then passes into collector channel entrances (CCE) along the SC external well...
December 24, 2016: Progress in Retinal and Eye Research
https://www.readbyqxmd.com/read/27951739/phytochemical-antioxidant-and-protective-effect-of-cactus-cladodes-extract-against-lithium-induced-liver-injury-in-rats
#17
Anouar Ben Saad, Brahmi Dalel, Ilhem Rjeibi, Amani Smida, Sana Ncib, Nacim Zouari, Lazhar Zourgui
CONTEXT: Opuntia ficus-indica (L.) Mill. (Castaceae) (cactus) is used in Tunisian medicine for the treatment of various diseases. OBJECTIVE: This study determines phytochemical composition of cactus cladode extract (CCE). It also investigates antioxidant activity and hepatoprotective potential of CCE against lithium carbonate (Li2CO3)-induced liver injury in rats. MATERIALS AND METHODS: Twenty-four Wistar male rats were divided into four groups of six each: a control group given distilled water (0...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/27935696/cyanobacteriochrome-photoreceptors-lacking-the-canonical-cys-residue
#18
Keiji Fushimi, Nathan C Rockwell, Gen Enomoto, Ni-Ni-Win, Shelley S Martin, Fei Gan, Donald A Bryant, Masahiko Ikeuchi, J Clark Lagarias, Rei Narikawa
Cyanobacteriochromes (CBCRs) are cyanobacterial photoreceptors that sense near-ultraviolet to far-red light. Like the distantly related phytochromes, all CBCRs reported to date have a conserved Cys residue (the "canonical Cys" or "first Cys") that forms a thioether linkage to C3(1) of the linear tetrapyrrole (bilin) chromophore. Detection of ultraviolet, violet, and blue light is performed by at least three subfamilies of two-Cys CBCRs that require both the first Cys and a second Cys that forms a second covalent linkage to C10 of the bilin...
December 20, 2016: Biochemistry
https://www.readbyqxmd.com/read/27932085/development-of-a-sensitive-and-false-positive-free-pma-qpcr-viability-assay-to-quantify-vbnc-escherichia-coli-and-evaluate-disinfection-performance-in-wastewater-effluent
#19
Richard J Kibbee, Banu Örmeci
The detection and quantification of viable Escherichia coli cells in wastewater treatment plant effluent is very important as it is the main disinfection efficacy parameter for assessing its public health risk and environmental impact. The aim of this study was to develop a sensitive and false-positive free propidium monoazide-quantitative polymerase chain reaction (PMA-qPCR) assay to quantify the viable but non-culturable (VBNC) E. coli present in secondary wastewater effluent after chlorine disinfection. The qPCR target was the E...
January 2017: Journal of Microbiological Methods
https://www.readbyqxmd.com/read/27913817/the-contribution-of-response-conflict-multisensory-integration-and-body-mediated-attention-to-the-crossmodal-congruency-effect
#20
Francesco Marini, Daniele Romano, Angelo Maravita
The crossmodal congruency task is a consolidated paradigm for investigating interactions between vision and touch. In this task, participants judge the elevation of a tactile target stimulus while ignoring a visual distracter stimulus that may occur at a congruent or incongruent elevation, thus engendering a measure of visuo-tactile interference (crossmodal congruency effect, CCE). The CCE reflects perceptual, attentional, and response-related factors, but their respective roles and interactions have not been set out yet...
December 2, 2016: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
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