Olivier Chazouillères, Pascal Potier, Charlotte Bouzbib, Bertrand Hanslik, Alexandra Heurgue, Eric NGuyen-Khac, Jérôme Gournay, Florence Tanne, Christophe Bureau, Marc Bourlière, Nathalie Ganne-Carrié, Victor de Lédinghen
Primary sclerosing cholangitis (PSC) is a rare and chronic cholestatic liver disease of unknown cause commonly associated with inflammatory bowel disease (IBD) and characterized by progressive obliterative fibro-inflammation of the biliary tree. Although the natural course is highly variable, PSC is often progressive, leading to biliary cirrhosis and its complications. In addition, PSC is a condition harbouring broad neoplastic potential with increased susceptibility for the development of both biliary and colon cancer...
January 2022: Clinics and Research in Hepatology and Gastroenterology