keyword
https://read.qxmd.com/read/38015013/surgical-outcome-of-a-patient-with-bertolotti-s-syndrome-in-whom-the-established-castellvi-classification-system-failed-illustrative-case
#21
JOURNAL ARTICLE
Richard J Chung, Camryn Harvie, John O'Donnell, Sarah Jenkins, Arthur L Jenkins
BACKGROUND: Bertolotti's syndrome is a condition of the lower back and/or L5 distribution leg pain caused by a lumbosacral transitional vertebra (LSTV). Diagnosing the LSTV as the cause of the symptoms and condition is essential for accurate management of this syndrome. Castellvi's classification system is widely accepted for LSTV anatomy, but it measures only one aspect of transitional anatomy and was intended primarily to identify target-level disk herniations. OBSERVATIONS: In this case, the Castellvi classification system failed to identify the patient (with 2 years of back and L5 pain) as having an LSTV, even though he displayed LSTV-like anatomy because both L5 transverse process heights measured less than 19 mm...
February 13, 2023: J Neurosurg Case Lessons
https://read.qxmd.com/read/37976486/results-from-a-prospective-clinical-study-us-npower-evaluating-a-miniature-spinal-cord-stimulator-for-the-management-of-chronic-intractable-pain
#22
JOURNAL ARTICLE
Mehul J Desai, Tejal Raju, Chheany Ung, Sailesh Arulkumar, Leo Kapural, Mayank Gupta, Kasra Amirdelfan, David Rosenfeld, Aaron Calodney, Dawood Sayed, Ajay Antony, Sean Li, Ramana Naidu, Joel Ackerman, Robert Ball, Michael Fishman, Peter Staats, Gary Heit, Shilpa Kottalgi, James Makous
BACKGROUND: Chronic, intractable, neuropathic pain is readily treatable with spinal cord stimulation (SCS). Technological advancements, including device miniaturization, are advancing the field of neuromodulation. OBJECTIVES: We report here the results of an SCS clinical trial to treat chronic, low back and leg pain, with a micro-implantable pulse generator (micro-IPG). STUDY DESIGN: This was a single-arm, prospective, multicenter, postmarket, observational study...
November 2023: Pain Physician
https://read.qxmd.com/read/37972544/evaluation-of-lumbar-adhesiolysis-using-a-radiofrequency-catheter-during-epiduroscopy-in-the-treatment-of-failed-back-surgery-syndrome-fbss
#23
JOURNAL ARTICLE
Roberto Gazzeri, Susanna Tribuzi, Matteo Luigi Giuseppe Leoni, Fabrizio Micheli, Felice Occhigrossi
Failed back surgery syndrome (FBSS) is a complication of spinal surgery that results in severe and disabling back/leg pain. Epiduroscopy is a percutaneous minimally invasive surgical technique used in the treatment of lumbar radicular pain that enables both direct visualization of epidural adhesions in patients with FBSS and the mechanical release of fibrotic scars in the epidural space. Although the use of a balloon catheter during epiduroscopy can usually remove adhesions between the dura and the vertebrae, in the thickest areas of fibrosis, the use of a catheter with a molecular quantum resonance radiofrequency generator may resect hard epidural fibrotic obstructions...
November 16, 2023: Surgical Technology International
https://read.qxmd.com/read/37933469/tumor-induced-osteomalacia-a-case-report-and-etiological-analysis-with-literature-review
#24
Zhenhao Zhang, Jiaxin Li, Zhicai Zhang, Zengwu Shao
BACKGROUND: Tumor-induced osteomalacia (TIO) belongs to a rare disease of the paraneoplastic syndrome. Phosphate uric mesenchymal tumor (PMT) is the most common cause of TIO, while the possibility of other tumors cannot be excluded. CASE PRESENTATION: We present a case of a 36-year-old female patient with systemic skeletal abnormalities. The woman complained of low back pain with mild motor dysfunction for 2 years. Laboratory examination showed abnormalities in markers of bone metabolism, parathyroid hormone (PTH), vitamin D and serum phosphorus...
November 7, 2023: Orthopaedic Surgery
https://read.qxmd.com/read/37916347/predictive-factors-for-treatment-success-of-epidural-steroid-injections-in-patients-with-lumbar-spinal-surgery
#25
JOURNAL ARTICLE
S Kokar, R Sacaklidir, Y Olgun, S Sencan, O H Gunduz
OBJECTIVE: The efficacy of epidural steroid injections (ESIs) in the treatment of radicular pain in patients undergoing lumbar spinal surgery is still unclear. The aim of this study was to investigate the factors affecting the success of ESIs in the treatment of ongoing radicular pain in patients undergoing lumbar spinal surgery. PATIENTS AND METHODS: This study was designed as a single-center, retrospective study, and was conducted at a Pain Management Center of a tertiary care center...
October 2023: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/37891739/microstructural-changes-in-the-spinothalamic-tract-of-cpss-patients-preliminary-results-from-a-single-center-diffusion-weighted-magnetic-resonance-imaging-study
#26
JOURNAL ARTICLE
Richard L Witkam, Lara S Burmeister, Johan W M Van Goethem, Anja G van der Kolk, Kris C P Vissers, Dylan J H A Henssen
INTRODUCTION: Chronic pain after spinal surgery (CPSS), formerly known as failed back surgery syndrome, encompasses a variety of highly incapacitating chronic pain syndromes emerging after spinal surgery. The intractability of CPSS makes objective parameters that could aid classification and treatment essential. In this study, we investigated the use of cerebral diffusion-weighted magnetic resonance imaging. METHODS: Cerebral 3T diffusion-weighted (DW-) MRI data from adult CPSS patients were assessed and compared with those of healthy controls matched by age and gender...
September 26, 2023: Brain Sciences
https://read.qxmd.com/read/37823035/chronic-pain-after-spine-surgery-insights-into-pathogenesis-new-treatment-and-preventive-therapy
#27
REVIEW
Qichao Wu, Xiang Cui, Leo C Guan, Chi Zhang, Jing Liu, Neil C Ford, Shaoqiu He, Xueming Chen, Xu Cao, Lei Zang, Yun Guan
UNLABELLED: Chronic pain after spine surgery (CPSS) is often characterized by intractable low back pain and/or radiating leg pain, and has been reported in 8-40% of patients that received lumbar spine surgery. We conducted a literature search of PubMed, MEDLINE/OVID with a focus on studies about the etiology and treatments of CPSS and low back pain. Our aim was to provide a narrative review that would help us better understand the pathogenesis and current treatment options for CPSS. This knowledge will aid in the development of optimal strategies for managing postoperative pain symptoms and potentially curing the underlying etiologies...
September 2023: Journal of Orthopaedic Translation
https://read.qxmd.com/read/37799188/metalloproteinase-2-in-failed-back-surgery-syndrome-caused-by-epidural-fibrosis-can-it-play-a-role-in-persistent-pain
#28
JOURNAL ARTICLE
Joanna Bielewicz, Beata Daniluk, Piotr Kamieniak
PURPOSE: Failed Back Surgery Syndrome (FBSS) occurs in 10-40% of patients treated surgically due to disk herniation (DH). There are several factors that can cause a predisposition to FBSS, but the exact pathomechanism has not been elucidated. The aim of this study was to investigate Metalloproteinase-2 (MMP-2) and Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) activities in a homogeneous group of FBSS patients with epidural fibrosis in comparison to its activity in patients with surgically treated DH...
2023: Frontiers in Human Neuroscience
https://read.qxmd.com/read/37753793/effect-of-spinal-cord-stimulation-on-quality-of-life-and-opioid-consumption-in-patients-with-failed-back-surgery-syndrome
#29
JOURNAL ARTICLE
Mohamed Amgad Elsayed Elkholy, Ahmed Nagaty, Ahmad Elsayed Abdelbar, Hisham Abdelsalam Mohamed Simry, Ahmed M Raslan
BACKGROUND: Failed back surgery syndrome (FBSS) is a constellation of conditions occurring after spine surgeries, characterized by the presence of persistent or recurring low back pain that has a significant impact on patients' quality of life. Neuromodulation in the form of Spinal Cord Stimulation (SCS) is considered an indispensable treatment modality in the management of certain chronic pain conditions and it is showing good results for improvement in pain scores and functional capacity of the FBSS patients...
September 27, 2023: Pain Practice: the Official Journal of World Institute of Pain
https://read.qxmd.com/read/37709550/pregabalin-versus-gabapentin-efficacy-in-the-management-of-neuropathic-pain-associated-with-failed-back-surgery-syndrome
#30
JOURNAL ARTICLE
Laith Thamer Al-Ameri, Mohammed Emad Shukri, Ekhlas Khalid Hameed, Ahmed Abed Marzook
OBJECTIVE: Failed back surgery syndrome (FBSS) is a common long-term complication following spine surgeries characterized by chronic persistent pain; different strategies of management were employed to deal with it. This clinical trial aims to compare the efficacy of Pregabalin and Gabapentin in the management of this condition. METHODS: A double-blind, randomized, comparative study (clinical trial registry NCT05324761 on 11th April 2022) with two parallel arms with Pregabalin and Gabapentin were used in arms one and two, respectively...
September 15, 2023: Journal of Korean Neurosurgical Society
https://read.qxmd.com/read/37673231/ecm-engineered-electrospun-fibers-with-an-immune-cascade-effect-for-inhibiting-tissue-fibrosis
#31
JOURNAL ARTICLE
Ming Qian, Shun Li, Kun Xi, Jincheng Tang, Xiaofeng Shen, Yong Liu, Ran Guo, Nannan Zhang, Yong Gu, Yun Xu, Wenguo Cui, Liang Chen
Tissue regeneration/fibrosis after injury is intricately regulated by the immune cascade reaction and extracellular matrix (ECM). Dysregulated cascade signal could jeopardize tissue homeostasis leading to fibrosis. Bioactive scaffolds mimicking natural ECM microstructure and chemistry could regulate the cascade reaction to achieve tissue regeneration. The current study constructed an ECM-engineered micro/nanofibrous scaffold using self-assembled nanofibrous collagen and decorin (DCN)-loaded microfibers to regulate the immune cascade reaction...
September 4, 2023: Acta Biomaterialia
https://read.qxmd.com/read/37642628/treatment-of-refractory-low-back-pain-using-passive-recharge-burst-in-patients-without-options-for-corrective-surgery-findings-and-results-from-the-distinct-study-a-prospective-randomized-multicenter-controlled-trial
#32
RANDOMIZED CONTROLLED TRIAL
Timothy Deer, Christopher Gilligan, Steven Falowski, Mehul Desai, Julie Pilitsis, Jessica Jameson, Susan Moeschler, Robert Heros, Edward Tavel, Anne Christopher, Denis Patterson, Sayed Wahezi, Jacqueline Weisbein, Ajay Antony, Robert Funk, Mohab Ibrahim, Chi Lim, Derron Wilson, Michael Fishell, Keith Scarfo, David Dickerson, Edward Braun, Patrick Buchanan, Robert M Levy, Nathan Miller, Jonathan Duncan, Jijun Xu, Kenneth Candido, Scott Kreiner, Marie E Fahey, James Yue
OBJECTIVE: Spinal cord stimulation (SCS) is effective for relieving chronic intractable pain conditions. The Dorsal spInal cord STImulatioN vs mediCal management for the Treatment of low back pain study evaluates the effectiveness of SCS compared with conventional medical management (CMM) in the treatment of chronic low back pain in patients who had not undergone and were not candidates for lumbar spine surgery. METHODS AND MATERIALS: Patients were randomized to passive recharge burst therapy (n = 162) or CMM (n = 107)...
October 2023: Neuromodulation: Journal of the International Neuromodulation Society
https://read.qxmd.com/read/37635617/medical-ozone-treatment-on-prevention-of-epidural-fibrosis-in-the-rat-model
#33
JOURNAL ARTICLE
H Dayanir, D Dayanir, G Emmez, H Emmez, S N Akyol, N Iseri, O M Uludag, M Kavutcu, C Ozogul, A C Babacan
BACKGROUND/AIM: Epidural fibrosis is one of the problems that can be seen after spinal surgery. The aim of this study was to investigate the possible preventive role of medical ozone (O) treatment on epidural fibrosis. MATERIALS AND METHODS: Twenty-four Sprague Dawley rats were randomly split into four groups: control (C), O, laminectomy (L), and L+O groups. Animals in the C group were sacrificed at the beginning of the experiment. The L and L+O groups had L procedure, while O treatment was supplied for the O and O+L groups...
August 2023: Nigerian Journal of Clinical Practice
https://read.qxmd.com/read/37609700/investigation-of-the-intraoperative-cortical-responses-to-spinal-motor-mapping-in-a-patient-with-chronic-pain
#34
JOURNAL ARTICLE
Deepak Berwal, Ilknur Telkes, Shruti Agarwal, Steven Paniccioli, Kevin McCarthy, Marisa DiMarzio, Bryan McLaughlin, Julie G Pilitsis
Intraoperative neurophysiological monitoring (IONM) in spinal cord stimulation (SCS) surgery for chronic pain is shown to provide effective guidance during device placement. Electromyography (EMG) is utilized to determine the laterality of the paddle. In some SCS cases due to patient physiology, laterality cannot be obtained via EMG. Electroencephalography (EEG) is already used in IONM to monitor cortical responses. Here, we show proof-of-concept of assessing the responses of epidurally evoked EMGs simultaneously with EEGs to determine laterality during IONM-using a high-resolution (HR) SCS paddle...
August 23, 2023: Journal of Neurophysiology
https://read.qxmd.com/read/37584698/severity-of-spinal-degeneration-does-not-affect-the-pain-reduction-under-continuous-epidural-analgesia
#35
JOURNAL ARTICLE
Vincent J Heck, Bastian Himpe, Juan M Vinas-Rios, Tobias Prasse, Michael J Pflüger, Maximilian Lenz, Sven Schmidt, Paul Kessler, Michael Rauschmann
PURPOSE: To outline clinical effectiveness of continuous epidural analgesia (CEA) in patients with failed back surgery syndrome (FBSS) or lumbar spinal stenosis (LSS) depending on severity of spinal degeneration. METHODS: In this retrospective cohort study, all patients with FBSS or LSS who underwent CEA within an inpatient rehabilitation program were evaluated. The pain reduction was measured by VAS on an hourly basis. Substantial pain reduction was defined as a minimal clinically important difference (MCID) > 50%...
August 16, 2023: European Spine Journal
https://read.qxmd.com/read/37575867/prevalence-of-chronic-pain-after-spinal-surgery-a-systematic-review-and-meta-analysis
#36
REVIEW
Hotoon S Alshammari, Abdullah S Alshammari, Sulaiman A Alshammari, Shaik Shaffi Ahamed
Degenerative disc disease and low back pain are common challenges that persist even after a discectomy. However, characterizations and quantifications of these illnesses from the patients' perspective are insufficient. We aimed to perform a systematic review of the literature and meta-analysis to determine the frequency of chronic pain after spinal surgery. We searched MEDLINE (PubMed), Google Scholar, and the Saudi Digital Library to retrieve research articles describing the frequency of persistent back pain, reoccurring disc herniation, and undergoing another operation following primary lumbar discectomy...
July 2023: Curēus
https://read.qxmd.com/read/37554655/case-report-utilizing-diffusion-weighted-mri-on-a-patient-with-chronic-low-back-pain-treated-with-spinal-cord-stimulation
#37
Isaiah Ailes, Mashaal Syed, Caio M Matias, Laura Krisa, Jingya Miao, Anish Sathe, Islam Fayed, Abdulaziz Alhussein, Peter Natale, Feroze B Mohamed, Kiran Talekar, Mahdi Alizadeh
Diffusion-weighted magnetic resonance imaging (dwMRI) has increasingly demonstrated greater utility in analyzing neuronal microstructure. In patients with chronic low back pain (cLBP), using dwMRI to observe neuronal microstructure can lead to non-invasive biomarkers which could provide clinicians with an objective quantitative prognostic tool. In this case report, we investigated dwMRI for the development of non-invasive biomarkers by conducting a region-based analysis of a 55-year-old male patient with failed back surgery syndrome (FBSS) treated with spinal cord stimulation (SCS)...
2023: Front Neuroimaging
https://read.qxmd.com/read/37512066/failed-back-surgery-syndrome-no-longer-a-surgeon-s-defeat-a-narrative-review
#38
REVIEW
Grzegorz Miękisiak
The introduction of the term Persistent Spinal Pain Syndrome (PSPS-T1/2), replacing the older term Failed Back Surgery Syndrome (FBSS), has significantly influenced our approach to diagnosing and treating post-surgical spinal pain. This comprehensive review discusses this change and its effects on patient care. Various diagnostic methods are employed to elucidate the underlying causes of back pain, and this information is critical in guiding treatment decisions. The management of PSPS-T1/2 involves both causative treatments, which directly address the root cause of pain, and symptomatic treatments, which focus on managing the symptoms of pain and improving overall function...
July 6, 2023: Medicina
https://read.qxmd.com/read/37493478/thinking-beyond-the-site-of-surgery-in-failed-back-surgery-syndrome-two-cases-with-parathyroid-adenoma-and-meningioma
#39
JOURNAL ARTICLE
Damla Yürük, Hüseyin Alp Alptekin
No abstract text is available yet for this article.
July 2023: Journal of the Turkish Society of Algology
https://read.qxmd.com/read/37409553/combined-cervical-and-thoracic-spinal-cord-stimulation-for-chronic-pain-a-systematic-literature-review
#40
REVIEW
Hao Tan, Mohamed A Elkholy, Ahmed M Raslan
OBJECTIVES: Spinal cord stimulation (SCS) is conventionally placed at either cervical or thoracic spinal regions to treat chronic pain. However, for patients with multiarea pain, concomitant cervical and thoracic SCS (ctSCS) may be necessary to provide sufficient coverage. It remains unknown whether ctSCS is effective and safe. Thus, we aimed to survey the existing literature and assess the efficacy and safety of ctSCS. METHODS: A systematic review of the literature was performed according to the 2020 PRISMA guidelines to investigate pain, functional, and safety outcomes related to ctSCS...
July 6, 2023: Pain Practice: the Official Journal of World Institute of Pain
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