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Pain medicine research

Órla Gilheaney, Leo Fa Stassen, Margaret Walshe
PURPOSE: Temporomandibular disorders (TMDs) are caused by changes in the structure and/or function of the temporomandibular joint, masticatory muscles, and/or osseous components. TMDs can result in oral stage dysphagia (OD) with potential effects on function and patient well-being. Little is known about the prevalence, nature, and management of TMD-related OD. The aims of the present study were to estimate the prevalence and nature of OD in adult TMD patients and to identify the common management techniques used to manage the signs and symptoms of TMD-related OD...
February 20, 2018: Journal of Oral and Maxillofacial Surgery
Thomas Berk, Stephen D Silberstein
BACKGROUND: Lidocaine, an amide anesthetic, has been used in the treatment of a wide variety of pain disorders for over 75 years. In addition to pain control, lidocaine is an anti-arrhythmic agent and has anti-inflammatory properties. Lidocaine's unique properties, including nonlinear pharmacokinetics, have limited its modern-day use. OBJECTIVE: The purpose of this review is to offer a better understanding of the properties of this unique treatment, which we hope will allow more practitioners to offer this to their patients...
March 14, 2018: Headache
Mackensie A Yore, Matthew C Strehlow, Lily D Yan, Elizabeth A Pirrotta, Joan L Woods, Koy Somontha, Yim Sovannra, Lauren Auerbach, Rebecca Backer, Christophe Grundmann, Swaminatha V Mahadevan
BACKGROUND: Emergency medicine is a young specialty in many low- and middle-income countries (LMICs). Although many patients seeking emergency or acute care are children, little information is available about the needs and current treatment of this group in LMICs. In this observational study, we sought to describe characteristics, chief complaints, management, and outcomes of children presenting for unscheduled visits to two Cambodian public hospitals. METHODS: Children enrolled in the study presented without appointment for treatment at one of two Cambodian public referral hospitals during a 4-week period in 2012...
March 13, 2018: International Journal of Emergency Medicine
J Niro, P Panel
OBJECTIVE: In women with symptomatic endometriosis and no desire for pregnancy, hysterectomy with or without bilateral oophorectomy is often presented as a definitive solution to their symptoms. Despite this radical treatment, it should be known that nearly 15% of these patients will have persistent pain. Thus the objective of this review was to determine the interest of total hysterectomy with or without bilateral oophorectomy for the treatment of deep endometriosis. METHOD: The research was conducted from the US National Library of Medicine's National Institutes of Health from the following keywords: endometriosis, hysterectomy, oophorectomy, ovariectomy, radical treatment...
March 9, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
James Watson, Robert M Barker-Davies, Alexander N Bennett, Daniel T P Fong, Patrick C Wheeler, Mark Lewis, Craig Ranson
Objective: Several lower limb tendinopathy treatment modalities involve identification of pathological paratendinous or intratendinous neovascularisation to target proposed co-location of painful neoneuralisation. The ability to reliably locate and assess the degree of neovascularity is therefore clinically important. The Modified Ohberg Score (MOS) is frequently used to determine degree of neovascularity, but reliability has yet to be established among Sport and Exercise Medicine (SEM) consultants...
2018: BMJ Open Sport & Exercise Medicine
Maira Rezende Formenton, Marco Aurélio Amador Pereira, Denise Tabacchi Fantoni
Massage therapy is becoming increasingly popular in human and animal physiotherapy and rehabilitation. Wider application of the technique led to research efforts aimed at providing scientific support to anecdotal beneficial effects, particularly pain relief. Recent studies have shown that massage therapy alters dopamine and serotonin levels, decreases noradrenaline levels, and modulates the immune system. Psychological effects such as reduction of stress and anxiety, with improvement of depressive patients, have been reported in humans...
December 2017: Topics in Companion Animal Medicine
Neil Blumberg, Jill M Cholette, Anthony P Pietropaoli, Richard Phipps, Sherry L Spinelli, Michael P Eaton, Suzie A Noronha, Jerard Seghatchian, Joanna M Heal, Majed A Refaai
Crystalloid infusion is widely employed in patient care for volume replacement and resuscitation. In the United States the crystalloid of choice is often normal saline. Surgeons and anesthesiologists have long preferred buffered solutions such as Ringer's Lactate and Plasma-Lyte A. Normal saline is the solution most widely employed in medical and pediatric care, as well as in hematology and transfusion medicine. However, there is growing concern that normal saline is more toxic than balanced, buffered crystalloids such as Plasma-Lyte and Lactated Ringer's...
February 21, 2018: Transfusion and Apheresis Science
Shokouhsadat Hamedi, Masoud Honarvar
BACKGROUND: Beta vulgaris (family: Chenopodiacea) is now much used in the food industry as a rich source of sugar but it is much less considered in medicine. Beet has been used in traditional medicine for hundreds of years to treat a variety of diseases such as constipation, decreased libido, gut and joint pain and dandruff. METHODS: This study introduced the benefits of Beta vulgaris by reviewing of Iranian traditional documents from 10th century until now and also compared modern phytotherapy of plant beet from the electronic data banks such as ISI, Pub Med and Scopus with findings that extracted from traditional literature...
March 8, 2018: Current Drug Discovery Technologies
Jaqui Walker, Pippa Hutchison, Junbo Ge, Dong Zhao, Yongjun Wang, Peter M Rothwell, J Michael Gaziano, Andrew Chan, John Burn, John Chia, Ruth Langley, Valerie O'Donnell, Bianca Rocca, Chris Hawkey
Acetylsalicylic acid was first synthesised by Dr FeIix Hoffman on 10th August 1897 and Aspirin was born. It quickly became the best-known pain killer in the world and in the 120 years since this event, aspirin has continued to attract interest, innovation and excitement. Set within the walls of the preserved ruins of Rudolf Virchow's lecture hall at Charité, within Berlin's Museum of Medical History, the International Aspirin Foundation's 28th Scientific Conference served to facilitate international, multi-disease, multidisciplinary discussion about the current understanding of aspirin's mechanisms of action and its utility in modern medicine as well as ideas for future research into its multifaceted applications to enhance global health...
2018: Ecancermedicalscience
Beth D Darnall, Maisa S Ziadni, Anuradha Roy, Ming-Chih Kao, John A Sturgeon, Karon F Cook, Kate Lorig, John W Burns, Sean C Mackey
BACKGROUND: The Institute of Medicine (IOM) reported that chronic pain affects about 100 million U.S. adults, with chronic low back pain (CLBP) cited as the most prevalent type. Pain catastrophizing is a psychological construct shown to predict the development and trajectory of chronic pain and patient response to pain treatments. While effective treatment for pain catastrophizing typically includes eight-session groups of cognitive behavioral therapy (CBT), a single-session targeted treatment class yielded promising results which, if replicated and extended, could prove to efficiently and cost-effectively reduce pain catastrophizing...
March 6, 2018: Trials
Kristian Thorborg, Michael P Reiman, Adam Weir, Joanne L Kemp, Andreas Serner, Andrea Mosler, Per Hölmich
Study Design Groin pain is common in athletes participating in multidirectional sports and has traditionally been considered a difficult problem to understand, diagnose, and manage. This may be due to sparse historical focus on this complex region in sports medicine. Until recently, there was no agreement regarding terminology, definitions, and classification of groin pain in athletes. This has made clear communication between clinicians difficult, and the results of research difficult to interpret and implement into practice...
March 6, 2018: Journal of Orthopaedic and Sports Physical Therapy
Toshihiro Fukui
Background: Both acute aortic dissection and ruptured aortic aneurysm are leading causes of death in cardiovascular disease. These life-threatening conditions have recently been categorized as acute aortic syndrome. This review describes the etiology, clinical presentation, and therapeutic options for acute aortic syndrome including acute aortic dissection and ruptured aortic aneurysm. Main body: Several diagnostic tools for detecting these critical conditions have been developed including computed tomography, ultrasonography, magnetic resonance imaging, and laboratory tests...
2018: Journal of Intensive Care
Diane M Flynn, Linda H Eaton, Honor McQuinn, Ashley Alden, Alexa R Meins, Tessa Rue, David J Tauben, Ardith Z Doorenbos
Chronic pain is a significant problem among military personnel and a priority of the military health system. The U.S. Army Surgeon General's Pain Management Task Force recommends using telehealth capabilities to enhance pain management. This article describes the development and evaluation of a telehealth intervention (TelePain) designed to improve access to pain specialist consultation in the military health system. The study uses a wait-list controlled clinical trial to test: 1) effectiveness of the intervention, and 2) interviews to assess barriers and facilitators of the intervention implementation...
December 2017: Contemporary Clinical Trials Communications
Shu-Zhi Wang, Zheng-Hong Qin
Naja naja atra venom (NNAV) is composed of various proteins, peptides, and enzymes with different biological and pharmacological functions. A number of previous studies have reported that NNAV exerts potent analgesic effects on various animal models of pain. The clinical studies using whole venom or active components have confirmed that NNAV is an effective and safe medicine for treatment of chronic pain. Furthermore, recent studies have demonstrated that NNAV has anti-inflammatory and immune regulatory actions in vitro and in vivo...
February 28, 2018: Toxins
Hao Yu, Jian-Ling Du
Dioscorea nipponica, a famous traditional Chinese medicine, belongs to the Dioscoreaceae family and has been widely distributed in the north, northeast and Qinghai regions of China. With its root and rhizome as an important herb material, it has been applied in China for several thousand years. Traditional Chinese medicine reported that this plant had been used for relieving cough and asthma, eliminating rheumatic aches, alleviating pain and improving blood circulation. Modern pharmacology studies have confirmed that saponins, the major active compounds in this herb, have shown various pharmacological actions including anti-tumor, anti-inflammatory,lipid-lowering, anti-fungal and anti-virus activities...
December 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
Blake Murdoch, Amy Zarzeczny, Timothy Caulfield
OBJECTIVE: To identify the frequency and qualitative characteristics of stem cell-related marketing claims made on websites of clinics featuring common types of complementary and alternative medicine practitioners. The involvement of complementary and alternative medicine practitioners in the marketing of stem cell therapies and stem cell-related interventions is understudied. This research explores the extent to which they are involved and collaborate with medical professionals. This knowledge will help with identifying and evaluating potential policy responses to this growing market...
February 28, 2018: BMJ Open
Alfred Burger, Chad Miller, Bradley A Sharpe, Rachel E Thompson
BACKGROUND: Hospital Medicine has a widening scope of practice. This article provides a summary of recent highimpact publications for busy clinicians who provide care to hospitalized adults. METHODS: The authors reviewed articles published between March 2016 and March 2017 for the Update in Hospital Medicine presentations at the 2017 Society of Hospital Medicine and Society of General Internal Medicine annual meetings. Nine of the 20 articles presented were selected for this review based on the article quality and potential to influence practice...
February 27, 2018: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
Sandeep Rawat, Arun K Jugran, Indra D Bhatt, Ranbeer S Rawal
OBJECTIVES: Hedychium spicatum Buch. Ham. ex D.Don. (Family Zingiberaceae) is a rhizomatous herb, used in medicines, food, cosmetics and perfumery industries. Traditionally, it is widely used in treating inflammation, pain, asthma, foul breath, vomiting, diarrhoea, bronchitis, hiccough and blood diseases. This study systematically reviewed traditional and folk uses, pharmacological properties, bioactive compounds and market potential of H. spicatum. Research gaps and potential of future research have also been discussed...
February 27, 2018: Journal of Pharmacy and Pharmacology
Kimmo T Murto, Wesley Chen, Sherri L Katz, Deborah A Schwengel, Lisa M Elden, Kumar G Belani, David Gozal
Recent concerns have been raised about the quality and safety of adenotonsillectomy, a common surgery performed to treat obstructive sleep apnea (OSA) in children. OSA is a risk factor for opioid-related perioperative respiratory complications including those associated with anoxic brain injury or death. Our objective was to identify controversial issues related to the care of children with OSA. A standardized Delphi consensus technique involving an interdisciplinary group of 24 pediatric OSA experts identified 3 key issues: "postoperative disposition, preoperative screening, and pain management...
February 23, 2018: Anesthesia and Analgesia
Peter R Giacobbi, Jonathan Stewart, Keeley Chaffee, Anna-Marie Jaeschke, Meagan Stabler, George A Kelley
Introduction: Guided imagery involves the controlled visualization of detailed mental images. This integrative health technique is used for healing, health maintenance, or the treatment of specific conditions. Guided imagery is an integral part of mindfulness meditation, hypnosis, and various relaxation exercises. However, evidence to support the widespread use and dissemination of guided imagery interventions has been lacking. The purposes of this scoping review were to document the scope of health outcomes and disease processes examined by guided imagery researchers and the journal outlets where this work has been published...
December 2017: Progress in Preventive Medicine
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