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Pain medicine research

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https://www.readbyqxmd.com/read/28207666/are-they-complying-physicians-knowledge-attitudes-and-readiness-to-change-regarding-low-back-pain-treatment-guideline-adherence
#1
Sheera Epstein-Sher, Dena H Jaffe, Amnon Lahad
STUDY DESIGN: Cross-sectional survey of 145 primary care practitioners (PCPs). OBJECTIVE: To examine low back pain (LBP) guideline knowledge, readiness to implement (RTI) these guidelines, and LBP attitudes and beliefs among Israeli PCPs and determine whether physician age, guideline familiarity, and medical specialty affect these variables. SUMMARY OF BACKGROUND DATA: LBP is a common condition managed primarily by PCPs. Little is known, however, about physician's LBP knowledge, attitudes, and beliefs and how these factors (knowledge, A&B) influence their practice behavior...
February 15, 2017: Spine
https://www.readbyqxmd.com/read/28188613/the-non-inferiority-margins-in-migraine-research-nimm-survey
#2
Serena L Orr, Timothy Ramsay, Suzanne N Christie, David Dodick, Jonathan Gladstone, Dar Dowlatshahi
OBJECTIVES: To survey experts in Headache Medicine on their opinions regarding appropriate non-inferiority margins for outcomes commonly used in migraine research. METHODS: Members of the American Headache Society and the Canadian Headache Society were invited to participate in the Non-Inferiority Margins in Migraine Research (NIMM) survey. Adult and child neurologists with expertise in Headache Medicine were eligible to participate. The survey had a multiple choice format and comprised questions on respondent characteristics, eligibility, as well as expert opinion on non-inferiority margins for outcomes commonly used in trials of both prophylactic and acute interventions for migraine...
February 11, 2017: Headache
https://www.readbyqxmd.com/read/28184307/low-back-pain-and-foki-rs2228570-polymorphism-of-vitamin-d-receptor-in-athletes
#3
Sabina Cauci, Francesca Migliozzi, Carlo Simone Trombetta, Ilaria Venuto, Paola Saccheri, Luciana Travan, Giovanni Chiriacò
BACKGROUND: Low back pain (LBP) is common in athletes. LBP can be detrimental to athletic performance and health. Factors predisposing to LBP in athletes remain elusive and require further studies. We investigated whether carriage of a specific genotype and/or allele of vitamin D receptor gene (VDR) FokI polymorphism (rs2228570) was a risk factor for LBP in athletes of different sports disciplines. METHODS: This genotype/phenotype association case-control study included 60 Italian athletes (25 females and 35 males; mean age 33...
2017: BMC Sports Science, Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28181920/can-early-rehabilitation-on-the-general-ward-after-an-intensive-care-unit-stay-reduce-hospital-length-of-stay-in-survivors-of-critical-illness-a-randomized-controlled-trial
#4
Wolfgang Gruther, Karin Pieber, Irene Steiner, Cornelia Hein, Jörg Michael Hiesmayr, Tatjana Paternostro-Sluga
OBJECTIVE: The aim of this study was to evaluate if an early rehabilitation program for survivors of critical illness improves functional recovery, reduces length of stay, and reduces hospital costs. DESIGN: This was a prospective randomized controlled trial. Fifty-three consecutive survivors of critical illness were included in the study. After discharge from the intensive care unit, the intervention group received an early rehabilitation program, and the standard-care group received physical therapy as ordered by the primary care team...
February 8, 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28179260/medial-tibial-stress-syndrome-can-be-diagnosed-reliably-using-history-and-physical-examination
#5
M Winters, E W P Bakker, M H Moen, C C Barten, R Teeuwen, A Weir
BACKGROUND: The majority of sporting injuries are clinically diagnosed using history and physical examination as the cornerstone. There are no studies supporting the reliability of making a clinical diagnosis of medial tibial stress syndrome (MTSS). AIM: Our aim was to assess if MTSS can be diagnosed reliably, using history and physical examination. We also investigated if clinicians were able to reliably identify concurrent lower leg injuries. METHODS: A clinical reliability study was performed at multiple sports medicine sites in The Netherlands...
February 8, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28179114/medicinal-plants-used-to-treat-snakebite-in-central-america-review-and-assessment-of-scientific-evidence
#6
REVIEW
Peter Giovannini, Melanie-Jayne R Howes
ETHNOPHARMACOLOGICAL RELEVANCE: Every year between 1.2 and 5.5 million people worldwide are victims of snakebites, with about 400,000 left permanently injured. In Central America an estimated 5,500 snakebite cases are reported by health centres, but this is likely to be an underestimate due to unreported cases in rural regions. The aim of this study is to review the medicinal plants used traditionally to treat snakebites in seven Central American countries: Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua and Panama...
February 4, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28177194/concise-review-mesenchymal-stem-cells-for-functional-cartilage-tissue-engineering-taking-cues-from-chondrocyte-based-constructs
#7
Andrea R Tan, Clark T Hung
Osteoarthritis, the most prevalent form of joint disease, afflicts 9% of the U.S. population over the age of 30 and costs the economy nearly $100 billion annually in healthcare and socioeconomic costs. It is characterized by joint pain and dysfunction, though the pathophysiology remains largely unknown. Due to its avascular nature and limited cellularity, articular cartilage exhibits a poor intrinsic healing response following injury. As such, significant research efforts are aimed at producing engineered cartilage as a cell-based approach for articular cartilage repair...
February 8, 2017: Stem Cells Translational Medicine
https://www.readbyqxmd.com/read/28176363/antinociceptive-and-antihyperalgesic-activity-of-a-traditional-maya-herbal-preparation-composed-of-pouteria-campechiana-chrysophyllum-cainito-citrus-limonum-and-annona-muricata
#8
Myrna Déciga-Campos, Rolffy Ortiz-Andrade, Amanda Sanchez-Recillas, José Salvador Flores-Guido, Mario A Ramírez Camacho
Preclinical Research The purpose of this work was to assess the antinociceptive and antihyperalgesic properties of an herbal preparation, composed of four vegetal species: Pouteria campechiana (P. campechiana), Chrysophyllum cainito (C. cainito), Citrus limonum (C. limonum), and Annona muricata (A. muricata), that is commonly used in combination (PCCA) in traditional Mayan medicine for the treatment of diabetes and pain. An ethanolic extract of PCCA was prepared at a ratio of 1:1:1:1 for each plant. The systemic antinociceptive effect of PCCA extract (50-600 mg/kg, p...
February 8, 2017: Drug Development Research
https://www.readbyqxmd.com/read/28166266/medication-related-factors-associated-with-health-related-quality-of-life-in-patients-older-than-65-years-with-polypharmacy
#9
Alonso Montiel-Luque, Antonio Jesús Núñez-Montenegro, Esther Martín-Aurioles, Jose Carlos Canca-Sánchez, Maria Carmen Toro-Toro, José Antonio González-Correa
METHODS AND DESIGN: Objective: To describe the relationship between medication-related factors and the health-related quality of life in patients older than 65 years who use multiple medications (polypharmacy). Design: Cross-sectional descriptive study. Setting: Primary care. Participants: Patients older than 65 years who use multiple medications (n = 375). Measurements: The main outcome measure was health-related quality of life according to the EuroQol-5D instrument. Sociodemographic, clinical and medication-related variables were recorded during home interviews...
2017: PloS One
https://www.readbyqxmd.com/read/28160760/wrist-ankle-acupuncture-increases-pain-thresholds-in-healthy-adults
#10
Hai-Jin Bi, Guo-Cheng Wu, Yu-Yu He, Hong-Yun Chen, Shuang Zhou, Qing-Hui Zhou
Context • Wrist-ankle acupuncture (WAA) has been used to relieve both chronic and acute pain in China. Some research has shown that WAA can increase the pain thresholds in pain patients, but the ability of WAA to affect the pain thresholds in healthy adults is unknown. Objective • The study intended to assess the influence of WAA on the pain thresholds of healthy adults. Design • This is an observational study. Setting • This study was conducted in the School of Traditional Chinese Medicine at the Second Military Medical University (Shanghai, China)...
January 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/28160400/exploring-the-facets-of-empathy-and-pain-in-clinical-practice-a-review
#11
REVIEW
Jenny Roche, Dominic Harmon
BACKGROUND: Empathy is an essential element in providing quality patient care. The significance of empathy is even more striking in pain medicine, as chronic pain is notorious for the way it can compromise an individual, leaving him or her isolated and feeling misconceived. This review examines the role of empathy in pain medicine practice. METHODS: Current and past literature focusing on empathy and pain was searched for in PubMed, Science Direct, Medline (Ovid), Medline (Ebsco), Research Gate, and Google Scholar in July 2015...
February 3, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/28156454/evaluating-the-prognostic-effect-of-a-pain-classification-system-in-patients-with-advanced-cancer
#12
Kimberson Cochien Tanco, Ali Haider, Courtney Maligi, Minjeong Park, Diane D Liu, Eduardo Bruera
: 95 Background: The Edmonton Classification System for Cancer Pain (ECS-CP) has been shown to predict pain management complexity based on five features: pain mechanism, incident pain, psychological distress, addictive behavior, and cognitive function. The main objective of our study was to explore the association between increasing sum of negative ECS-CP features and achievement of good pain control at first follow up visit at an outpatient palliative care clinic. METHODS: Initial and follow up clinical information of 409 eligible supportive care outpatients such as patient demographics, ECS-CP assessment, morphine equivalent daily dose (MEDD), opioid rotation, Edmonton Symptom Assessment Score (ESAS), and personalized pain goal (PPG) were retrospectively reviewed and analyzed...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28143544/an-overview-of-the-practitioner-research-and-collaboration-initiative-praci-a-practice-based-research-network-for-complementary-medicine
#13
Amie Steel, David Sibbritt, Janet Schloss, Jon Wardle, Matthew Leach, Helene Diezel, Jon Adams
BACKGROUND: The Practitioner Research and Collaboration Initiative (PRACI) is an innovative, multi-modality practice-based research network (PBRN) that represents fourteen complementary medicine (CM) professions across Australia. It is the largest known PBRN for complementary healthcare in the world and was launched in 2015. The purpose of this paper is to provide an update on the progress of the PRACI project, including a description of the characteristics of PRACI members in order to facilitate further sub-studies through the PRACI PBRN...
February 1, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28125978/expectations-of-pain-and-functioning-in-patients-with-musculoskeletal-disorders-a-cross-sectional-study
#14
Sigrid Skatteboe, Cecilie Røe, Morten Wang Fagerland, Lars-Petter Granan
BACKGROUND: Research has suggested that patient expectations are associated with treatment outcome and evolve along with patient communication within the musculoskeletal field. However, few studies have investigated if or how physical medicine and rehabilitation (PMR) consultations affect the attending patients' expectations regarding pain and functional improvement. Hence, the aims of the present study were to compare patient expectations regarding pain and functional improvement before and after a PMR consultation and to assess patient characteristics, including diagnosis, that could perhaps predict changes in expectations...
January 26, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28125523/machine-learning-based-classification-of-38-years-of-spine-related-literature-into-100-research-topics
#15
David C Sing, Lionel N Metz, Stefan Dudli
STUDY DESIGN: Retrospective review. OBJECTIVE: To identify the top 100 spine research topics. SUMMARY OF BACKGROUND DATA: Recent advances in "machine learning," or computers learning without explicit instructions, have yielded broad technological advances. Topic modeling algorithms can be applied to large volumes of text to discover quantifiable themes and trends. METHODS: Abstracts were extracted from the National Library of Medicine PubMed database from five prominent peer-reviewed spine journals (European Spine Journal [ESJ], The Spine Journal [SpineJ], Spine, Journal of Spinal Disorders and Techniques [JSDT], Journal of Neurosurgery: Spine [JNS])...
January 25, 2017: Spine
https://www.readbyqxmd.com/read/28115867/sonographic-tracking-of-trunk-nerves-essential-for-ultrasound-guided-pain-management-and-research
#16
Ke-Vin Chang, Chih-Peng Lin, Chia-Shiang Lin, Wei-Ting Wu, Manoj K Karmakar, Levent Özçakar
Delineation of architecture of peripheral nerves can be successfully achieved by high-resolution ultrasound (US), which is essential for US-guided pain management. There are numerous musculoskeletal pain syndromes involving the trunk nerves necessitating US for evaluation and guided interventions. The most common peripheral nerve disorders at the trunk region include thoracic outlet syndrome (brachial plexus), scapular winging (long thoracic nerve), interscapular pain (dorsal scapular nerve), and lumbar facet joint syndrome (medial branches of spinal nerves)...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28114832/exhaustive-comfa-and-comsia-analyses-around-different-chemical-entities-a-ligand-based-study-exploring-the-affinity-and-selectivity-profiles-of-5-ht1a-ligands
#17
Sara Guariento, Silvia Franchini, Michele Tonelli, Paola Fossa, Claudia Sorbi, Elena Cichero, Livio Brasili
The 5-hydroxytryptamine (5-HT1A) receptors represent an attractive target in drug discovery. In particular, 5-HT1A agonists and partial agonists are deeply investigated for their potential role in the treatment of anxiety, depression, ischaemic brain disorder and more recently, of pain. On the other hand, 5-HT1A antagonists have been revealed promising compounds in cognition disorders and, lately, in cancer. Thus, the discovery of 5HT1A ligands is nowadays an appealing research activity in medicinal chemistry...
December 2017: Journal of Enzyme Inhibition and Medicinal Chemistry
https://www.readbyqxmd.com/read/28112552/acupuncture-for-the-treatment-of-peripheral-neuropathy-a-systematic-review-and-meta-analysis
#18
Alexandra Dimitrova, Charles Murchison, Barry Oken
OBJECTIVES: Neuropathy and its associated pain pose great therapeutic challenges. While there has been a recent surge in acupuncture use and research, little remains known about its effects on nerve function. This review aims to assess the efficacy of acupuncture in the treatment of neuropathy of various etiologies. METHODS: The Medline, AMED, Cochrane, Scopus, CINAHL, and clintrials.gov databases were systematically searched from inception to July 2015. Randomized controlled trials (RCTs) assessing acupuncture's efficacy for poly- and mononeuropathy were reviewed...
January 23, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28107855/a-close-look-at-an-integrative-treatment-package-for-bell-s-palsy-in-korea
#19
Seung Min Kathy Lee, Suji Lee, Jun Hyeong Park, Jongbae J Park, Sanghoon Lee
OBJECTIVE: To provide an overview of the integrative treatment package for Bell's palsy provided at Kyung Hee University Korean Medicine Hospital (KHU KMH). SUMMARY: The Facial Palsy Center at KHU KMH has been providing integrative treatment for Bell's palsy patients during the past three decades. Within 72 h of symptom onset, corticosteroids are recommended but complementary treatment including acupuncture and herbal medicine can be used to help suppress inflammation and nerve degeneration...
February 2017: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/28105524/perceptions-of-family-members-of-palliative-medicine-and-hospice-patients-who-experienced-music-therapy
#20
Lisa M Gallagher, Ruth Lagman, Debbie Bates, Melissa Edsall, Patricia Eden, Jessica Janaitis, Lisa Rybicki
PURPOSE: Evidence shows that music therapy aids in symptom management and improves quality of life for palliative medicine and hospice patients. The majority of previous studies have addressed patient needs, while only a few addressed the needs of family members. The primary purpose of this study was to understand family members' perceptions of music therapy experienced by a relative in palliative medicine or hospice. Patient self-reported scales and music therapist assessment of change were also investigated...
January 19, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
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