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influenza asthma

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https://www.readbyqxmd.com/read/28636411/asthma-and-influenza-vaccination-in-elderly-hospitalized-patients-matched-case-control-study-in-spain
#1
María Morales Suárez-Varela, Agustin Llopis, Estrella Fernandez-Fabrellas, Francisco Sanz, M Jose Perez-Lozano, Vicente Martin, Jenaro Astray, Jesús Castilla, Mikel Egurrola, Luis Force, Diana Toledo, Àngela Domínguez
OBJECTIVES: Influenza infection is an exacerbating factor for asthma, and its prevention is critical in managing asthmatic patients. We investigated the effect of influenza vaccination on asthmatic and non-asthmatic patients hospitalized with laboratory-confirmed influenza in Spain. METHODS: We made a matched case-control study to assess the frequency of hospitalization for influenza in people aged ≥65 years. Hospitalized patients with unplanned hospital admissions were recruited from 20 hospitals representing seven Spanish regions...
June 21, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28634031/does-atopy-affect-the-course-of-viral-pneumonia
#2
S B Erdem, D Can, S Girit, F Çatal, V Şen, S Pekcan, H Yüksel, A Bingöl, I Bostancı, D Erge, R Ersu
BACKGROUND: The presence of atopy is considered as a risk factor for severe respiratory symptoms in children. The objective of this study was to examine the effect of atopy on the course of disease in children hospitalised with viral pneumonia. METHODS: Children between the ages of 1 and 6 years hospitalised due to viral pneumonia between the years of 2013 and 2016 were included to this multicentre study. Patients were classified into two groups as mild-moderate and severe according to the course of pneumonia...
June 17, 2017: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/28633906/respiratory-syncytial-virus-rsv-in-adult-emergency-department-patients-do-emergency-providers-consider-rsv-as-an-admission-diagnosis-a-retrospective-observational-study-carried-out-at-massachusetts-general-hospital-boston-ma
#3
William Binder, Jill Thorsen, Pierre Borczuk
BACKGROUND: Respiratory Syncytial Virus (RSV) has been recognized for over half a century as a cause of morbidity in infants and children. Over the past 20years, data has emerged linking RSV as a cause of illness in adults resulting in 177,000 annual hospitalizations and up to 14,000 deaths among older adults. OBJECTIVE: Characterize clinical variables in a cohort of adult RSV patients. We hypothesize that emergency physicians do not routinely consider RSV in the differential diagnosis (DDx) of influenza like illness...
June 11, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28591866/effectiveness-of-influenza-vaccines-in-asthma-a-systematic-review-and-meta-analysis
#4
Eleftheria Vasileiou, Aziz Sheikh, Chris Butler, Karim El Ferkh, Beatrix von Wissmann, Jim McMenamin, Lewis Ritchie, Jürgen Schwarze, Nikolaos G Papadopoulos, Sebastian L Johnston, Lilly Tian, Colin R Simpson
There is uncertainty about the effectiveness of influenza vaccination in people with asthma and its impact on asthma outcomes, which may contribute to the sub-optimal vaccination rates in people with asthma. This systematic review and meta-analysis involved searching 12 international databases for randomized controlled trials (RCTs) and high quality quasi-experimental and epidemiological studies (1970 to 2016). The risk of bias was low for three included RCTs. The quality of three included observational studies was moderate...
June 7, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28544140/investigation-of-bronchiectasis-in-severe-uncontrolled-asthma
#5
Katerina Dimakou, Anna Gousiou, Michail Toumbis, Maria Kaponi, Serafeim Chrysikos, Loukas Thanos, Christina Triantafillidou
INTRODUCTION: The presence of bronchiectasis in patients with asthma varies in different reports, while a clear etiological relation has not been precisely established. OBJECTIVES: To investigate the presence of bronchiectasis in patients with severe uncontrolled asthma and examine whether they contribute to the severity of asthma. METHODS: Patients with severe asthma were prospectively recruited. HRCT of the chest was performed to identify and grade bronchiectasis using the "Smith" radiology scale...
May 24, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28542337/changes-in-hospitalizations-for-chronic-respiratory-diseases-after-two-successive-smoking-bans-in-spain
#6
Iñaki Galán, Lorena Simón, Elena Boldo, Cristina Ortiz, Rafael Fernández-Cuenca, Cristina Linares, María José Medrano, Roberto Pastor-Barriuso
BACKGROUND: Existing evidence on the effects of smoke-free policies on respiratory diseases is scarce and inconclusive. Spain enacted two consecutive smoke-free regulations: a partial ban in 2006 and a comprehensive ban in 2011. We estimated their impact on hospital admissions via emergency departments for chronic obstructive pulmonary disease (COPD) and asthma. METHODS: Data for COPD (ICD-9 490-492, 494-496) came from 2003-2012 hospital admission records from the fourteen largest provinces of Spain and from five provinces for asthma (ICD-9 493)...
2017: PloS One
https://www.readbyqxmd.com/read/28533080/influenza-vaccination-for-patients-with-chronic-obstructive-pulmonary-disease-implications-for-pharmacists
#7
Rasha M Arabyat, Dennis W Raisch, Ludmila Bakhireva
BACKGROUND: Influenza virus is responsible for substantial morbidity and mortality. Specific populations are at higher risk for exacerbations from influenza virus, such as patients with chronic obstructive pulmonary disease (COPD). Influenza vaccination coverage among COPD patients is low. Pharmacists can improve influenza vaccination among COPD patients by recognizing factors that influence vaccination and addressing these factors. OBJECTIVES: To (1) determine the recent influenza vaccination coverage among patients with COPD, (2) identify factors that were associated with immunization, and (3) interpret the results based upon Andersen's healthcare utilization model...
February 24, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28526665/the-sensor-study-protocol-for-a-mixed-methods-study-of-self-management-checks-to-predict-exacerbations-of-pseudomonas-aeruginosa-in-patients-with-long-term-respiratory-conditions
#8
Claire Roberts, Thomas L Jones, Samal Gunatilake, Will Storrar, Scott Elliott, Sharon Glaysher, Ben Green, Steven Rule, Carole Fogg, Ann Dewey, Kevin A Auton, Anoop J Chauhan
BACKGROUND: There are an estimated three million people in the United Kingdom with chronic obstructive pulmonary disease (COPD), and the incidence of bronchiectasis is estimated at around 0.1% but is more common in COPD and severe asthma. Both COPD and bronchiectasis are characterized by exacerbations in which bacteria play a central role. Pseudomonas aeruginosa is isolated from sputum samples from 4% to 15% of adults with COPD and is more likely to be isolated from patients with severe disease...
May 19, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28514782/a-systematic-review-and-meta-analysis-of-influenza-a-virus-infection-during-pregnancy-associated-with-an-increased-risk-for-stillbirth-and-low-birth-weight
#9
Jing He, Zhi-Wei Liu, Yong-Ping Lu, Tao-Yuan Li, Xu-Jing Liang, Petra C Arck, Si-Min Huang, Berthold Hocher, You-Peng Chen
BACKGROUND/AIMS: Impaired pregnancy outcomes, such as low birth weight are associated with increased disease risk in later life, however little is known about the impact of common infectious diseases during pregnancy on birth weight. The study had two aims: a) to investigate risk factors of influenza virus infection during pregnancy, and b) to analyze the impact of influenza virus infection on pregnancy outcome, especially birth weight. METHODS: Prospective and retrospective observational studies found in PubMed, MEDLINE, Embase, Google Scholar, and WangFang database were included in this meta analysis...
2017: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/28514204/factors-influencing-influenza-vaccination-among-south-korean-adult-asthma-patients-a-nationwide-population-based-cross-sectional-study
#10
Jae Ho Chung, Tae Ho Kim, Chang Hoon Han
BACKGROUND: It is important to identify factors associated with influenza vaccination. This study was performed to investigate factors associated with vaccination coverage among asthma patients in Korea. METHODS: Data were obtained from 229,121 participants (5,989 with asthma and 223,132 without asthma) in the 2010 Korean Community Health Survey. The demographic characteristics and socioeconomic status of respondents with and without asthma were compared. Univariate and multiple logistic regression analyses were used to evaluate socioeconomic status and other demographic variables potentially related to influenza vaccination in asthma patients...
May 17, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28482859/an-ethnopharmacological-evaluation-of-navapind-and-shahpur-virkanin-district-sheikupura-pakistan-for-their-herbal-medicines
#11
Maria Zahoor, Zubaida Yousaf, Tahreem Aqsa, Manahil Haroon, Nadia Saleh, Arusa Aftab, Sadia Javed, Mouzma Qadeer, Habiba Ramazan
BACKGROUND: The chief aim of this study was to enlist the ethnobotanical uses of wild plants in district Sheikhupura, province Punjab, Pakistan. Due to extreme geographical and climatic conditions, Pakistan has a great floral diversity. Plants have been used by the indigenous people for treatment of different ailments since long. They are still dependent on the plants for their domestic purposes. Moreover, plants are used as first aid to treat diverse ailments such as cold, cough, influenza, asthma, cancer, antidote, gastric and hepatic disorders...
May 8, 2017: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/28480255/risk-factors-for-influenza-associated-severe-acute-respiratory-illness-hospitalization-in-south-africa-2012-2015
#12
Stefano Tempia, Sibongile Walaza, Jocelyn Moyes, Adam L Cohen, Claire von Mollendorf, Florette K Treurnicht, Marietjie Venter, Marthi Pretorius, Orienka Hellferscee, Senzo Mtshali, Mpho Seleka, Akhona Tshangela, Athermon Nguweneza, Johanna M McAnerney, Nicole Wolter, Anne von Gottberg, Halima Dawood, Ebrahim Variava, Shabir A Madhi, Cheryl Cohen
BACKGROUND: Data on risk factors for influenza-associated hospitalizations in low- and middle-income countries are limited. METHODS: We conducted active syndromic surveillance for hospitalized severe acute respiratory illness (SARI) and outpatient influenza-like illness (ILI) in 2 provinces of South Africa during 2012-2015. We compared the characteristics of influenza-positive patients with SARI to those with ILI to identify factors associated with severe disease requiring hospitalization, using unconditional logistic regression...
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28432994/assessment-of-temporal-variation-for-the-risk-of-particulate-matters-on-asthma-hospitalization
#13
Hyomi Kim, Honghyok Kim, Yoon-Hyung Park, Jong-Tae Lee
Increased ambient concentration of particulate matters are considered as one of major causes for increased prevalence or exacerbation of asthma or asthma like symptoms. Recently, possible temporal variation in risks of PM on mortality has been suggested. We investigated short-term effect of both PM10 and PM2.5 on asthma hospitalization, and assessed temporal variation of PM risks in Seoul, Korea, 2003-2011. Generalized additive model was used to estimate PM risks on asthma hospitalization with consideration by long-term trend, influenza epidemic, day of week, meteorological factors...
July 2017: Environmental Research
https://www.readbyqxmd.com/read/28431562/effects-of-the-common-polymorphism-in-the-human-aldehyde-dehydrogenase-2-aldh2-gene-on-the-lung
#14
Aoi Kuroda, Ahmed E Hegab, Gao Jingtao, Shuji Yamashita, Nobuyuki Hizawa, Tohru Sakamoto, Hideyasu Yamada, Satoshi Suzuki, Makoto Ishii, Ho Namkoong, Takanori Asakura, Mari Ozaki, Hiroyuki Yasuda, Junko Hamamoto, Shizuko Kagawa, Kenzo Soejima, Tomoko Betsuyaku
BACKGROUND: Aldehyde dehydrogenases (ALDHs) play a major role in detoxification of aldehydes. High expression of ALDHs is a marker for stem cells of many organs including the lungs. A common polymorphism in ALDH2 gene (ALDH2*2) results in inactivation of the enzyme and is associated with alcohol flushing syndrome and increased risk for cardiovascular and Alzheimer's diseases and some cancers. The effect of this ALDH2 polymorphism on the lung and its stem cells has not been thoroughly examined...
April 21, 2017: Respiratory Research
https://www.readbyqxmd.com/read/28404355/asthma-exacerbations-among-asthmatic-children-receiving-live-attenuated-versus-inactivated-influenza-vaccines
#15
G Thomas Ray, Ned Lewis, Kristin Goddard, Pat Ross, Jonathan Duffy, Frank DeStefano, Roger Baxter, Nicola P Klein
OBJECTIVE: To investigate whether there is a difference in the risk of asthma exacerbations between children with pre-existing asthma who receive live attenuated influenza vaccine (LAIV) compared with inactivated influenza vaccine (IIV). MATERIAL AND METHODS: We identified IIV and LAIV immunizations occurring between July 1, 2007 and March 31, 2014 among Kaiser Permanente Northern California members aged 2 to <18years with a history of asthma, and subsequent asthma exacerbations seen in the inpatient or Emergency Department (ED) setting...
May 9, 2017: Vaccine
https://www.readbyqxmd.com/read/28401936/bmal1-links-the-circadian-clock-to-viral-airway-pathology-and-asthma-phenotypes
#16
A Ehlers, W Xie, E Agapov, S Brown, D Steinberg, R Tidwell, G Sajol, R Schutz, R Weaver, H Yu, M Castro, L B Bacharier, X Wang, M J Holtzman, J A Haspel
Patients with asthma experience circadian variations in their symptoms. However it remains unclear how specific aspects of this common airway disease relate to clock genes, which are critical to the generation of circadian rhythms in mammals. Here, we used a viral model of acute and chronic airway disease to examine how circadian clock disruption affects asthmatic lung phenotypes. Deletion of the core clock gene bmal1 or environmental disruption of circadian function by jet lag exacerbated acute viral bronchiolitis caused by Sendai virus (SeV) and influenza A virus in mice...
April 12, 2017: Mucosal Immunology
https://www.readbyqxmd.com/read/28393532/sex-bias-in-diagnostic-delay-in-bronchiectasis-an-analysis-of-the-spanish-historical-registry-of-bronchiectasis
#17
Rosa Ma Girón, Javier de Gracia Roldán, Casilda Olveira, Montserrat Vendrell, Miguel Ángel Martínez-García, David de la Rosa, Luis Máiz, Julio Ancochea, Liliana Vázquez, Luis Borderías, Eva Polverino, Eva Martínez-Moragón, Olga Rajas, Joan B Soriano
Diagnostic delay is common in most respiratory diseases, particularly in bronchiectasis. However, sex bias in diagnostic delay has not been studied to date. OBJECTIVE: Assessment of diagnostic delay in bronchiectasis by sex. METHODS: The Spanish Historical Registry of Bronchiectasis recruited adults diagnosed with bronchiectasis from 2002 to 2011 in 36 centres in Spain. From a total of 2113 patients registered we studied 2099, of whom 1125 (53.6%) were women. RESULTS: No differences were found for sex or age (61...
January 1, 2017: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/28390584/live-attenuated-influenza-vaccine-use-and-safety-in-children-and-adults-with-asthma
#18
Jonathan Duffy, Melissa Lewis, Theresa Harrington, Roger Baxter, Edward A Belongia, Lisa A Jackson, Steven J Jacobsen, Grace M Lee, Allison L Naleway, James Nordin, Matthew F Daley
BACKGROUND: Live attenuated influenza vaccine (LAIV) might increase the risk of wheezing in persons with asthma or children younger than 5 years with a history of recurrent wheezing. OBJECTIVE: To describe the use and assess the safety of LAIV in persons with asthma in the Vaccine Safety Datalink population. METHODS: We identified persons with asthma using diagnosis codes and medication records in 7 health care organizations over 3 influenza seasons (2008-2009 through 2010-2011) and determined their influenza vaccination rates...
April 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28382037/influenza-infection-in-mice-induces-accumulation-of-lung-mast-cells-through-the-recruitment-and-maturation-of-mast-cell-progenitors
#19
Behdad Zarnegar, Erika Mendez-Enriquez, Annika Westin, Cecilia Söderberg, Joakim S Dahlin, Kjell-Olov Grönvik, Jenny Hallgren
Mast cells (MCs) are powerful immune cells that mature in the peripheral tissues from bone marrow (BM)-derived mast cell progenitors (MCp). Accumulation of MCs in lung compartments where they are normally absent is thought to enhance symptoms in asthma. The enrichment of lung MCs is also observed in mice subjected to models of allergic airway inflammation. However, whether other types of lung inflammation trigger increased number of MCp, which give rise to MCs, is unknown. Here, mouse-adapted H1N1 influenza A was used as a model of respiratory virus infection...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28377198/pediatrician-maintenance-of-certification-using-american-board-of-pediatrics-performance-improvement-modules
#20
Marina Arvanitis, Neal A deJong, Laurel K Leslie, Darren A DeWalt, Gregory D Randolph, Kori B Flower
BACKGROUND: From 2010-2014, pediatricians completed Part 4 Maintenance of Certification (MOC) through practice- or organization-developed quality improvement (QI) activities approved by the American Board of Pediatrics (ABP). Organization-developed activities were online modules, such as the ABP's Performance Improvement Modules (PIMs), through which pediatricians implemented QI strategies in practice, and reported quality measures. OBJECTIVES: Aim 1) Assess the proportion of pediatricians who completed practice- vs organization-developed QI activities for Part 4 MOC, and test the relationship between activities and pediatrician demographics...
April 1, 2017: Academic Pediatrics
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