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https://www.readbyqxmd.com/read/29225020/arthroscopic-wafer-procedure-versus-ulnar-shortening-osteotomy-as-a-surgical-treatment-for-idiopathic-ulnar-impaction-syndrome
#1
Won-Taek Oh, Ho-Jung Kang, Yong-Min Chun, Il-Hyun Koh, Hae-Mo-Su An, Yun-Rak Choi
PURPOSE: To compare clinical and radiologic outcomes and complication rates of the arthroscopic wafer procedure (AWP) and ulnar shortening osteotomy (USO) for idiopathic ulnar impaction syndrome (UIS). METHODS: From May 2009 to June 2014, 42 patients who were aged 45 years or older with idiopathic UIS underwent either the AWP or USO under the following identical surgical indications: (1) less than 4 mm of positive ulnar variance, (2) Palmer classification 2C or 2D lesion of the triangular fibrocartilage complex, (3) stable distal radioulnar joint (DRUJ) and/or lunotriquetral joint, and (4) no evidence of osteoarthritis of the DRUJ or ulnocarpal joint...
December 7, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29193607/comparative-genomics-reveals-that-loss-of-lunatic-fringe-lfng-promotes-melanoma-metastasis
#2
Martin Del Castillo Velasco-Herrera, Louise van der Weyden, Jeremie Nsengimana, Anneliese O Speak, Marcela K Sjöberg, D Timothy Bishop, Göran Jönsson, Julia Newton-Bishop, David J Adams
Metastasis is the leading cause of death in patients with advanced melanoma, yet the somatic alterations that aid tumour cell dissemination and colonization are poorly understood. Here, we deploy comparative genomics to identify and validate clinically relevant drivers of melanoma metastasis. To do this we identified a set of 976 genes whose expression level was associated with a poor outcome in patients from two large melanoma cohorts. Next, we characterised the genomes and transcriptomes of mouse melanoma cell lines defined as weakly metastatic, and their highly metastatic derivatives...
November 29, 2017: Molecular Oncology
https://www.readbyqxmd.com/read/29178063/evaluation-of-the-performance-of-three-tenodesis-techniques-for-the-treatment-of-scapholunate-instability-flexion-extension-and-radial-ulnar-deviation
#3
Teresa Alonso-Rasgado, Qing-Hang Zhang, David Jimenez-Cruz, Colin Bailey, Elizabeth Pinder, Avanthi Mandaleson, Sumedh Talwalkar
Chronic scapholunate ligament (SL) injuries are difficult to treat and can lead to wrist dysfunction. Whilst several tendon reconstruction techniques have been employed in the management of SL instability, SL gap reappearance after surgery has been reported. Using a finite element model and cadaveric study data, we investigated the performance of the Corella, scapholunate axis (SLAM) and modified Brunelli tenodesis (MBT) techniques. Scapholunate dorsal and volar gap and angle were obtained following virtual surgery undertaken using each of the three reconstruction methods with the wrist positioned in flexion, extension, ulnar deviation and radial deviation, in addition to the ulnar-deviated clenched fist and neutral positions...
November 25, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29173053/alfred-walter-campbell-s-return-to-australia
#4
Malcolm Macmillan
Alfred Walter Campbell (1868-1937) established the basic cytoarchitectonic structure of the human brain while he was working as a pathologist at the Rainhill Lunatic Asylum near Liverpool in the United Kingdom. He returned to Australia in 1905 and continued doing research while establishing a neurological practice. His research over the next 17 years focused on four topics: (a) localisation in the cerebellum, (b) the neuroses and psychoses in war, (c) localisation in the cerebral cortex of the gorilla, and (d) the causes and pathology of the mysterious Australian "X" Disease (later known as Murray Valley encephalitis)...
November 27, 2017: Journal of the History of the Neurosciences
https://www.readbyqxmd.com/read/29167068/three-dimensional-morphology-of-lunate-surface-in-hip-dysplasia-theoretical-implications-for-periacetabular-osteotomy
#5
Meng Xu, Yanbing Wang, Lei Zhong, Yang Song, Jianlin Xiao, Yu Sun, Wei Li, Zhe Zhu, Xin Zhao, Jincheng Wang
BACKGROUND: The objective of this study was to evaluate three-dimensional morphology of acetabular lunate surface in patients with dysplastic hip using three-dimensional computed tomography (CT), and to compare the lunate surface morphology between the normal and dysplastic hips. METHODS: Sixty seven dysplastic hips in symptomatic patients and 61 normal hips in healthy volunteers who underwent three-dimensional CT scanning were included in this study. The size and shape of the lunate surface was measured with a fully automated imaging technique using Mimics16...
November 19, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/29166759/magnetic-resonance-imaging-assessed-synovial-and-bone-changes-in-hand-and-wrist-joints-of-rheumatoid-arthritis-patients
#6
Kyung-Ann Lee, Sang-Ho Min, Tae-Hyung Kim, Sang-Heon Lee, Hae-Rim Kim
Background/Aims: Magnetic resonance imaging (MRI) is a sensitive and useful method for the detection of synovitis and joint destruction in rheumatoid arthritis (RA) patients. However, the patterns of MRI-detected bone erosion, bone marrow edema (BME), synovitis, and tenosynovitis have received insufficient attention. Therefore, this study evaluated the patterns of bone erosion, BME, synovitis, and tenosynovitis, and calculated the RA-MRI score (RAMRIS) of patients with RA at the carpal and metacarpophalangeal (MCP) joints using MRI...
November 24, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29165016/the-use-of-osteochondral-flaps-in-the-treatment-of-carpal-disorders
#7
James P Higgins, Heinz K Bürger
Vascularized osteochondral flaps have been described for use in reconstruction of the wrist, providing the benefits of osteochondral grafts in addition to the benefit of osseous and subchondral perfusion via the microvascular pedicle. Various harvest sites have been described including the medial and lateral femoral trochlea and the proximal third metatarsal. The reconstructed surfaces described include the cartilage surfaces of the scaphoid, lunate, capitate and radius. The ability to transfer analogous osteochondral surfaces poses the possibility for new motion-preserving alternatives for difficult articular problems previously treated with salvage procedures...
January 1, 2017: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/29157783/effect-of-push-up-position-on-wrist-joint-pressures-in-the-intact-wrist-and-following-scapholunate-interosseous-ligament-sectioning
#8
Brett T Daly, Frederick W Werner, Salvatore M Cavallaro, Emily R Tucci, Brian J Harley
PURPOSE: To determine the contact pressures between the scaphoid and lunate and the distal radius during 2 wrist push-up positions before and following scapholunate interosseous ligament (SLIL) sectioning. METHODS: Eight fresh cadaveric wrists were tested in a neutral flexion-extension (knuckle) push-up position and in an extended push-up position. Pressure measurements were acquired as each wrist was loaded with the wrist in extension and with the wrist in a neutral position...
November 17, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29146508/biomechanical-analysis-of-palmar-midcarpal-instability-and-treatment-by-partial-wrist-arthrodesis
#9
Sarah A Shiga, Frederick W Werner, Marc Garcia-Elias, Brian J Harley
PURPOSE: To create a biomechanical model of palmar midcarpal instability by selective ligament sectioning and to analyze treatment by simulated partial wrist arthrodesis. METHODS: Nine fresh-frozen cadaver arms were moved through 3 servohydraulic actuated motions and 2 passive wrist mobilizations. The dorsal radiocarpal, triquetrohamate, scaphocapitate, and scaphotrapeziotrapezoid ligaments were sectioned to replicate palmar midcarpal instability. Kinematic data for the scaphoid, lunate, and triquetrum were recorded before and after ligament sectioning and again after simulated triquetrohamate arthrodesis (TqHA) and radiolunate arthrodesis (RLA)...
November 14, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29132239/lunate-fractures-and-associated-radiocarpal-and-midcarpal-instabilities-a-systematic-review
#10
Meenalochani Shunmugam, Joideep Phadnis, Amy Watts, Gregory I Bain
The aim of this study was to analyse lunate fractures and any associated osseo-ligamentous injuries. A systematic review identified 34 cases. We identified carpal instabilities at the radiocarpal and midcarpal joints in volar and dorsal directions. Radiocarpal instabilities (10/34) were usually dorsoradial (8/10), with a transverse lunate fracture, best seen on a coronal image. Midcarpal instabilities (24/34) were usually volar (14/18), with a volar lunate shear fracture, best seen on a sagittal image. Instabilities were sub-classified into non-displaced, subluxated and dislocated...
January 1, 2017: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/29117852/the-resignation-of-sir-william-charles-ellis
#11
Andrew J Howe
Sir William Ellis (1780-1839) was superintendent of the West Riding Pauper Lunatic Asylum and Hanwell Asylum. He was a practitioner of moral therapy and non-restraint. He added his own religious aspects to his treatment based on his personal experiences. These interventions were novel and benefitted his patients. However, he is less well known in the present day than his contemporaries who also championed non-restraint. In 1838, he left Hanwell Asylum, as he disagreed with plans to expand patient capacity. The resurgence of Whig politics at the time also played its part in his resignation...
November 2017: Journal of Medical Biography
https://www.readbyqxmd.com/read/29117840/very-distal-radius-wedge-osteotomy-for-kienb%C3%A3-ck-s-disease-case-series
#12
Hirotaka Okubo, Chojo Futenma, Hideyuki Sunagawa, Masaki Kinjo, Fuminori Kanaya
BACKGROUND: Radius osteotomy is one of the standard surgical procedures for the treatment of Kienböck's disease. Unfortunately, radius osteotomy can result in an incongruous distal radio-ulnar joint (DRUj) postoperatively, because the procedure is performed proximal to the DRUj. METHODS: A very distal radius wedge osteotomy was performed as a 15-degree lateral closing wedge osteotomy with the apex of the wedge distal to that of conventional lateral closing wedge osteotomy; this procedure was developed to avoid postoperative incongruous DRUj...
December 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/29105588/results-of-scaphocapitate-arthrodesis-with-lunate-excision-in-advanced-kienb%C3%A3-ck-disease-at-10-7-year-mean-follow-up
#13
Amaury Charre, Stephanie Delclaux, Costel Apredoai, Jean-Emmanuel Ayel, Michel Rongieres, Pierre Mansat
Scaphocapitate arthrodesis with lunate excision was performed for treatment of advanced Kienböck disease in 17 patients (18 wrists). Ten were women and seven men. Five were Lichtmann Stage IIIA, 12 Stage IIIB, and one Stage IV. Minimum follow-up period was 24 months; mean follow-up was 10.7 years (range 2.3 to 22 years, SD 7.1). At the latest follow-up, six patients were very satisfied, nine were satisfied and two were disappointed. Pain was significantly decreased in all cases. Wrist mobility was unchanged...
January 1, 2017: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/29092991/lunate-morphology-as-a-risk-factor-of-idiopathic-ulnar-impaction-syndrome
#14
J H Park, W Y Jang, D H Kwak, J W Park
AIMS: Positive ulnar variance is an established risk factor for idiopathic ulnar impaction syndrome (UIS). However, not all patients with positive ulnar variance develop symptomatic UIS and other factors, including the morphology of the lunate, may be involved. The aim of this study was to clarify the relationship between lunate morphology and idiopathic UIS. PATIENTS AND METHODS: A cohort of 95 patients with idiopathic UIS (UIS group) was compared with 95 asymptomatic controls with positive ulnar variance...
November 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/29091489/interobserver-agreement-in-diagnosing-early-stage-kienb%C3%A3-ck-disease-on-radiographs-and-magnetic-resonance-imaging
#15
Wouter F van Leeuwen, Stein J Janssen, Thierry G Guitton, Neal Chen, David Ring
BACKGROUND: The appearance of early Kienböck disease on radiographs and magnetic resonance imaging (MRI) may be difficult to distinguish from other conditions that affect the lunate. We aimed to assess the interobserver agreement in the diagnosis of early Kienböck disease when evaluated on different imaging modalities. METHODS: Forty-three hand surgeon members of the Science of Variation Group were randomized to evaluate radiographs and 35 hand surgeons to evaluate radiographs and MRI scans of 26 patients for the presence of Kienböck disease, the lunate type, and the ulnar variance...
November 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/29068934/resurfacing-capitate-pyrocarbon-implant-versus-proximal-row-carpectomy-alone-a-comparative-study-to-evaluate-the-role-of-capitate-prosthetic-resurfacing-in-advanced-carpal-collapse
#16
COMPARATIVE STUDY
Francesco Giacalone, Pietro G di Summa, Alessandro Fenoglio, Arman Sard, Elisa Dutto, Matteo Ferrero, Maddalena Bertolini, Marc Garcia-Elias
BACKGROUND: The Resurfacing Capitate Pyrocarbon Implant associated with proximal row carpectomy has been used to treat symptomatic advanced carpal collapse, widening the indications of proximal row carpectomy to patients with capitate head arthritis. The authors retrospectively compared their case series of implant versus carpectomy alone, analyzing whether prosthetic implant outcomes could be similar to those of proximal row carpectomy even with a higher stage of osteoarthritis. METHODS: Fifty-seven patients who underwent surgery for wrist osteoarthritis (minimum follow-up, 2 years) were selected retrospectively...
November 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29061430/treatment-of-maternal-depression-in-urban-slums-of-karachi-pakistan-a-randomized-controlled-trial-rct-of-an-integrated-maternal-psychological-and-early-child-development-intervention
#17
Nusrat Husain, Farah Zulqernain, Lesley-Anne Carter, Imran B Chaudhry, Batool Fatima, Tayyeba Kiran, Nasim Chaudhry, Shehla Naeem, Farhat Jafri, Farah Lunat, Sami Ul Haq, Meher Husain, Chris Roberts, Farooq Naeem, Atif Rahman
BACKGROUND: Maternal depression is a major public health problem. This may affect a mother's ability to provide adequate care for the child. The objective of this study was to evaluate the effectiveness of the Learning through Play Plus program (LTP Plus) - a parenting program integrated with Cognitive Behaviour Therapy (CBT). METHODS: A total of 247 women with symptoms of depression in Karachi, Pakistan were assigned randomly to either LTP Plus or routine care (Clinical Trials Identifier: NCT00835016)...
October 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/29058964/combined-bilateral-carpal-coalition-of-the-scaphoid-and-trapezium-and-of-the-lunate-and-triquetrum
#18
Sarah S Nagel, U Kneser, B Bickert
No abstract text is available yet for this article.
January 1, 2017: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/29033290/nonvascularized-cartilage-grafts-versus-vascularized-cartilage-flaps-comparison-of-cartilage-quality-6%C3%A2-months-after-transfer-and-isolated-from-surrounding%C3%A2-bone-ingrowth
#19
James P Higgins, Farzad Borumandi, Heinz K Bürger, Mehmet Emre Benlidayı, Anna Vasilyeva, Leman Sencar, Sait Polat, Alexander J Gaggl
PURPOSE: Subchondral perfusion of osteochondral grafts has been shown to be important in preventing long-term cartilage degeneration. In carpal reconstruction, subchondral perfusion from the graft bed is limited. This study's purpose was to compare the histological characteristics of cartilage in osteochondral grafts supported by synovial imbibition alone to cartilage of vascularized osteochondral flaps that have both synovial and vascular pedicle perfusion. METHODS: Two adjacent osteochondral segments were harvested on the medial femoral trochlea in domestic 6- to 8-month-old pigs...
October 12, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28991585/arthroscopic-assisted-partial-wrist-arthrodesis
#20
REVIEW
Eva-Maria Baur
Partial wrist arthrodesis (PWA) is a well-known procedure for treating degenerative or posttraumatic wrist conditions. Four-corner fusion (4CF) is mostly used for scapholunate advanced collapse and scaphoid nonunion advanced collapse. The author performed 39 procedures, including 4CFs, 2-corner fusions, 3-corner fusions, scaphoid-capitate/scaphoid-capitate-lunate fusions, scaphoid-trapezium-trapezoid arthrodeses, and radioscapholunate arthroscopic PWAs (A-PWAs). There were 8 revision cases including 4 partial nonunions...
November 2017: Hand Clinics
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