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https://www.readbyqxmd.com/read/28598048/hepatotoxicity-in-hiv-patients-an-observational-study-in-patients-from-tertiary-care-centre-of-western-india
#1
Smrati Bajpai, Kavita Joshi
OBJECTIVE: HIV AIDS has currently become a chronic manageable condition with HAART, but with its chronicity and lifelong therapy currently the adverse drug reactions to these drugs are the main concern for any treating physician. Hepatotoxicity is one of the prime concerns of any physician managing HIV patients. We observe a number of patients reporting hepatotoxicity in our cohort and this had great impact on the efficacy and intake of the HAART drugs, this led us to explore this area and to find out the prevalence and etiologies in our cohort...
May 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28585604/drug-addiction-and-diabetes-south-asian-action
#2
Yatan Pal Singh Balhara, Sanjay Kalra
Both diabetes and drug addiction are common phenomena across the world. Drug abuse impacts glycaemic control in multiple ways. It becomes imperative, therefore, to share guidance on drug deaddiction in persons with diabetes. The South Asian subcontinent is home to specific forms and patterns of drug abuse. Detailed study is needed to ensure good clinical practice regarding the same. This communication provides a simple and pragmatic framework to address this issue, while calling for concerted action on drug deaddiction in South Asia...
June 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28262143/prevalence-of-dual-diagnosis-among-clinic-attending-patients-in-a-de-addiction-centre-of-a-tertiary-care-hospital
#3
Bhagyalakshmi Nanjayya Subodh, Nandita Hazari, Deeksha Elwadhi, Debasish Basu
BACKGROUND & AIMS: Indian research on dual diagnosis is mostly on prevalence of co-morbidity in a particular type of substance use disorder or psychiatric disorder. They were not on overall prevalence of dual diagnosis in a clinical sample. The study aims to assess prevalence of dual diagnosis among first time visitors to a tertiary care deaddiction centre. METHODOLOGY: The study participants were recruited using computer-generated random number table from 10th Apr 2013 to 28 June 2013 from a deaddiction centre in North India...
February 2017: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/28207998/benzodiazepine-and-z-drug-dependence-data-from-a-tertiary-care-center
#4
Lekhansh Shukla, Spandana Bokka, Tulika Shukla, Arun Kandasamy, Prabhat Chand, Vivek Benegal, Pratima Murthy
Objective: To examine the clinical characteristics and course of benzodiazepine and �Z-drug� dependence in patients presenting to a tertiary deaddiction center in southern India. Methods: Case files of 950 inpatients admitted between January 2007 and January 2014 who reported benzodiazepine or Z-drug use were reviewed. Patients (n = 170) with an ICD-10 diagnosis of mental and behavioral disorders due to the use of sedatives or hypnotics-dependence syndrome currently using substance (F13...
February 16, 2017: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/27891376/smokeless-tobacco-and-stroke-a-clinico-epidemiological-follow-up-study-in-a-tertiary-care-hospital
#5
Subhransu Sekhar Jena, Shobhitendu Kabi, Baikuntha Nath Panda, B C Kameswari, Payal, Ishwar Chandra Behera, Subrat Kumar Tripathy, Seemanchana Mahanta
INTRODUCTION: Among the modifiable risk factors for stroke, tobacco smoking is well recognized. In some studies the use of Smokeless Tobacco (ST) has also been contributed as a risk factor for ischemic stroke. Use of ST is very common in South-East Asia. The form of ST varies according to the geographical and cultural variation. AIM: To study the various clinical symptoms and radiological findings of stroke due to different types of ST. MATERIALS AND METHODS: This was a prospective hospital based study carried out over a period of 2 years...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/25568482/a-case-report-of-pornography-addiction-with-dhat-syndrome
#6
M S Darshan, T S Sathyanarayana Rao, Sam Manickam, Abhinav Tandon, Dushad Ram
A case of pornography addiction with dhat syndrome was diagnosed applying the existing criteria for substance dependence in International Classification for Diseases-10 and Diagnostic and Statistical Manual of Mental Disorders Fourth Edition, Text Revision. There is a lack of clear-cut criteria for identifying and defining such behavioural addictions and also lack of medical documents on pornography addiction. An applied strategy in lines with any substance addiction is used, and we found it helped our patient to gradually deaddict and then completely quit watching pornography...
October 2014: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/25013316/relationship-of-reasons-and-fears-of-treatment-with-outcome-in-substance-using-population-attending-a-de-addiction-centre
#7
Siddharth Sarkar, Naresh Nebhinani, Jasveen Kaur, Kamalpreet Kaur, Sandhya Ghai, Debasish Basu
BACKGROUND: Substance users approach a treatment facility for a variety of reasons as well as avoid or delay in help seeking due to perceived fears with treatment facilities. Sometimes these factors might be associated with treatment outcomes. OBJECTIVES: We studied the relationship of reasons and fears of treatment seeking with treatment outcome in substance users. MATERIALS AND METHODS: One hundred subjects, attending the Drug Deaddiction and Treatment Centre, PGIMER, were prospectively recruited by purposive sampling...
July 2013: Industrial Psychiatry Journal
https://www.readbyqxmd.com/read/24459376/metabolic-syndrome-among-substance-dependent-men-a-study-from-north-india
#8
Surendra Kumar Mattoo, Naresh Nebhinani, Munish Aggarwal, Debasish Basu, Parmanand Kulhara
BACKGROUND: Substance abuse, alcohol in particular, is associated with increased risk of diabetes and metabolic syndrome (MS). The relationship between the substance abuse and MS is complex and the literature is sparse. OBJECTIVES: The present research was aimed to study the prevalence and predictors of MS among outpatients with substance dependence. MATERIALS AND METHODS: Patients with substance dependence were recruited from a deaddiction center in North India, who attended outpatient clinic from 1(st) January, 2010-31(st) December, 2010...
January 2013: Industrial Psychiatry Journal
https://www.readbyqxmd.com/read/24459367/demographic-and-clinical-profile-of-substance-abusing-women-seeking-treatment-at-a-de-addiction-center-in-north-india
#9
Naresh Nebhinani, Siddharth Sarkar, Sunil Gupta, Surendra Kumar Mattoo, Debasish Basu
BACKGROUND: In the recent decades increasing number of women have been seeking deaddiction services. Despite that the report data is very limited from India. OBJECTIVES: The present research aimed to study the demographic and clinical profile of women seeking deaddiction treatment at a tertiary care center in North India. MATERIALS AND METHODS: Retrospective structured chart review of 100 women substance abusers seeking treatment at a deaddiction center between September 1978 and December 2011...
January 2013: Industrial Psychiatry Journal
https://www.readbyqxmd.com/read/24309871/seroprevalence-of-human-immunodeficiency-virus-hepatitis-b-surface-antigen-and-hepatitis-c-in-substance-dependents-admitted-in-a-tertiary-hospital-at-amritsar-india
#10
Harsh Chalana, Harjot Singh, Jasmine Kaur Sachdeva, Shivangi Sharma
Substance dependents often seek help for deaddiction and are detected positive during routine viral markers testing. We screened such patients in our hospital ShriGuru RamDas Institute of Medical Sciences and Research (SGRDIMSR) which is situated in a rural area adjoining the city of Amritsar; being a tertiary care centre it caters to a large population. A total of 1382 patients were admitted to the psychiatry ward from 01 July 2009 to 31 December 2012 and screened for study, out of whom 4.63% (n=64) refused to consent for participation in the study...
December 2013: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/24049231/metabolic-syndrome-in-alcohol-dependent-men-a-cross-sectional-study
#11
Jitender Aneja, Debasish Basu, Surendra Kumar Mattoo, Krishan Kumar Kohli
BACKGROUND: In the context to mental illness metabolic syndrome (MS) has gained significant attention in the last decade. The present research aimed to study the prevalence of MS and its correlates among the alcohol-dependent men at a deaddiction center in Northern India. MATERIALS AND METHODS: A cross-sectional analysis was done for consecutive male subjects who met the diagnosis of alcohol-dependence syndrome currently using alcohol according to the International Clinical Diagnostic criteria- tenth revision mental and behavioral disorder- Clinical description and diagnostic guidelines criteria (ICD-10)...
April 2013: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/23814713/effect-of-alcohol-withdrawl-on-glutathione-s-transferase-total-antioxidant-capacity-and-amylase-in-blood-and-saliva-of-alcohol-dependent-males
#12
Neethumol Peter, Kevin J Chiramel, Shivashankara A R
INTRODUCTION: Alcohol biomarkers help in the early detection of alcoholism and its complications. There is a paucity of studies in India on the salivary markers of systemic diseases in general and on salivary alcohol biomarkers in particular. OBJECTIVES: The present study was aimed at assessing the effect of alcohol withdrawal on the antioxidants and amylase in blood and saliva, and at finding the correlation between the blood and the salivary parameters in alcoholics...
May 2013: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/23302058/comparison-of-craving-between-smoked-and-smokeless-tobacco-across-a-variety-of-cue-exposures
#13
COMPARATIVE STUDY
Siddharth Sarkar, Akhilesh Sharma, Debasish Basu
Smokeless tobacco use is a major health issue but has received less attention in craving research. The present non-funded study aimed to assess craving associated with smokeless tobacco compared to smoked forms. Forty-eight nicotine dependent male subjects attending a deaddiction center in India were recruited. The subjects were exposed to six nicotine related and two control cues in random order for variable time durations. The urge to consume the tobacco product was rated. Tobacco-related cues produced different patterns and degrees of craving among users of smoked and smokeless tobacco...
February 2013: Substance Use & Misuse
https://www.readbyqxmd.com/read/23162192/reasons-for-help-seeking-and-associated-fears-in-subjects-with-substance-dependence
#14
Naresh Nebhinani, Siddharth Sarkar, Sandhya Ghai, Debasish Basu
BACKGROUND: Patients seek treatment for substance use disorders because of certain reasons that they consider significant and important, but on the other hand, they do have various fears or apprehensions about the treatment, which act as barriers for treatment-seeking. In this study, we aim to assess their reasons for seeking treatment, the associated fears about treatment, their social support and locus of control, and also to find the relationship among these variables. MATERIALS AND METHODS: One hundred subjects attending the Drug Deaddiction and Treatment Center, Postgraduate Institute of Medical Education and Research (PGIMER) were prospectively recruited, with purposive sampling from 15 June to 14 July, 2011...
April 2012: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/23105741/association-of-hyperhomocysteinemia-to-alcohol-withdrawal-in-chronic-alcoholics
#15
K Devika Rani, N Suneetha, Shruti Mohanty, Pragna Rao
This study is conducted in chronic alcoholics to assess the association of an Individual's level of serum homocysteine with the success of achieving alcohol deaddiction in the patient. The patients' nutrition status is also assessed. 50 chronic alcoholics admitted to a deaddiction center were inducted into the study. Patients underwent an 8 weeks holistic program to promote rehabilitation from alcoholism. All the patients were addicted to alcohol for 8 - 10 years. Of the 50 patients enrolled, 39 of them completed the 8 weeks program including complete abstinence from alcohol during this period...
April 2008: Indian Journal of Clinical Biochemistry: IJCB
https://www.readbyqxmd.com/read/23050896/tramadol-versus-clonidine-in-management-of-heroin-withdrawl
#16
Somsubhra Chattopadhyay, O P Singh, Amit Bhattacharyya, Subrata Sen, Paromita Roy, Sharmistha Debnath
UNLABELLED: Opiod dependence is one of the leading psychiatric morbidities in India. The deaddiction centres are meager in number; stigma attached to admission in deaddiction centre is high and most addicts want outpatient treatment so that they do not miss daily wages. Several recent reports stated effectiveness of tramadol in treating opioid withdrawal. This study attempts to compare effectiveness of tramadol with clonidine in opioid withdrawal. METHODOLOGY: A total of 60 patients having heroin dependence were selected and out of them 30 got clonidine treatment and the other 30 got tramadol treatment...
December 2010: Asian Journal of Psychiatry
https://www.readbyqxmd.com/read/21965954/rapid-increase-of-heroin-dependence-in-delhi-some-initial-observations
#17
S Saxena, D Mohan
The present paper documents and discusses the rapid increase in the problem of heroin dependence in the city of Delhi in the recent years. Initial observations on patients with heroin dependence attending the Deaddiction Clinic of a large general hospital are described with difficulties encountered in the clinical management of these patients. It is suggested that sustained efforts be made to control this problem because heroin is likely to give rise to medical and social consequences of serious nature in the near future...
January 1984: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/21897457/agnihotra-in-the-treatment-of-alcoholism
#18
G R Golechha, I G Sethi, Deshpande, U Rani
Agnihotra is a Vedic ritual of litting fire in a copper pyramid pot with use of Mantras at sunrise and sunset time. It is found to have neurophysiological effect on human body and brain. Clinically it produces mental tranquility and reported to have useful adjunct effect on deaddiction. In our present study effect of Agnihotra was studied on 18 cases of alcoholism. It is found that it leads to total abstinence without other restrain after 2 weeks of continuous Agnihotra practice. An obsessive compliance to perform Agnihotra develops...
January 1991: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/21743630/a-psychodemographic-study-of-the-patients-of-a-deaddiction-centre-in-madras
#19
R Ponnudurai, J Jayakar, B Raju, R Pattamuthu
Sixty patients who reported to a Deaddiction Centre were investigated with regard to their psychodemographic profile. 53.3% of them turned out to be exclusively alcohol abusers, 35% were abusers of alcohol concurrently with other substances and 11.7% were abusers of exclusively drugs. Those who consumed alcohol alone, commenced their intake at a mean age of 24.4 years and reported for treatment only at 39.2 years; this was in contrast to the mean age of 17.9 years at which alcohol use begin in those who took alcohol in combination with other substances...
July 1993: Indian Journal of Psychiatry
https://www.readbyqxmd.com/read/21584114/coping-behaviours-in-recent-abstinence-attempt-in-opioid-dependent-subjects
#20
H R Pal, B S Chavan
Failure of coping machanisms in handling urges when exposed to high risk situations has been posited as one of the factors associated with relapse of drug use. In the present study there has been an attempt to study the coping mechanisms used by opioid dependent subjects in a recent abstinence attempt. The sample consisted of 100 opioid dependent subjects admitted to the deaddiction centre at A.I.I.M.S. New Delhi. The subjects should have had an abstinence longer than a month's period in the 1 year prior to the study...
January 1996: Indian Journal of Psychiatry
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