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https://www.readbyqxmd.com/read/29218835/-we-just-follow-the-patients-lead-healthcare-professional-perspectives-on-the-involvement-of-teenagers-with-cancer-in-decision-making
#1
Emma Day, Louise Jones, Richard Langner, L Caroline Stirling, Rachael Hough, Myra Bluebond-Langner
PURPOSE: We report on an in-depth interview and participant observation study that uses data from multiple sources to determine how the involvement of teenagers with leukaemia is understood and enacted in healthcare. In this article, we investigate healthcare professionals' (HCP) views of teenagers' involvement in decisions about their care and treatment for leukaemia. METHODS: We conducted participant observation at 98 multi-disciplinary meetings and 95 open-ended, semi-structured interviews and informal conversations with clinical teenage cancer teams at one UK tertiary referral centre...
December 8, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29194695/a-grounded-theory-study-of-how-couples-desist-from-intimate-partner-violence
#2
Lisa V Merchant, Jason B Whiting
Intimate partner violence is a common and damaging experience for many couples, and therapists struggle to address it adequately (Johnson, 2008). Despite its negative effects, many violent couples stay together, with some stopping their violent behaviors. Unfortunately, we know little about the systemic factors affecting violence desistance. This study used grounded theory methods to analyze the process of desistance in formerly violent couples. A model of desistance consisting of three categories was developed, which for most couples included a (a) Turning Point, (b) Decision to Change, and (c) Doing Things Differently...
December 1, 2017: Journal of Marital and Family Therapy
https://www.readbyqxmd.com/read/29186214/things-we-do-for-no-reason-electrolyte-testing-in-pediatric-acute-gastroenteritis
#3
Carrie H Lind, David P Johnson
BACKGROUND: HASH(0x3cd7e58) OBJECTIVE: HASH(0x3bf4c58) DESIGN, SETTING, PATIENTS: HASH(0x2dadf20) INTERVENTION: HASH(0x3395690) MEASUREMENTS: HASH(0x3c0cff8) CONCLUSIONS: HASH(0x3cdac70)
November 22, 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29186072/a-dependable-localization-algorithm-for-survivable-belt-type-sensor-networks
#4
Mingqiang Zhu, Fei Song, Lei Xu, Jung Taek Seo, Ilsun You
As the key element, sensor networks are widely investigated by the Internet of Things (IoT) community. When massive numbers of devices are well connected, malicious attackers may deliberately propagate fake position information to confuse the ordinary users and lower the network survivability in belt-type situation. However, most existing positioning solutions only focus on the algorithm accuracy and do not consider any security aspects. In this paper, we propose a comprehensive scheme for node localization protection, which aims to improve the energy-efficient, reliability and accuracy...
November 29, 2017: Sensors
https://www.readbyqxmd.com/read/29170321/24%C3%A2-an-audit-into-the-number-of-patients-suffering-out-of-hospital-cardiac-arrest-that-are-resuscitated-despite-a-high-likelihood-of-futility
#5
Mia Cokljat, Gareth Clegg, Scott Clarke
BACKGROUND: For a significant number of patients suffering out-of-hospital cardiac arrest (OHCA) cardiopulmonary resuscitation (CPR) is likely to be futile and attempting it may be the wrong thing to do. Anticipatory care plans with do-not-attempt cardiopulmonary resuscitation (DNACPR) instructions exist to prevent this. Anecdotally we felt that many patients present to our Emergency Department (ED) with ongoing resuscitation which was not in their best interests. The aim of this study was to establish the proportion of patients arriving in our ED with ongoing CPR who had low, intermediate or high risk of futility...
December 2017: Emergency Medicine Journal: EMJ
https://www.readbyqxmd.com/read/29154483/evaluating-the-effectiveness-of-mental-health-nursing-interventions
#6
EDITORIAL
Marie Crowe
While acknowledging that not all that we do as mental health nurses is quantifiable and much of the art of our practice defies measurement, it is important to consider whether what we do is effective for service users on their journey to recovery. The evaluation of what we do is important for the survival of mental health nursing as a profession and for ensuring that the interventions we provide are useful for service users and their families. We are long past the days of doing things just because that is what has always been done and we are moving on from an emphasis on nurse-focussed research...
November 20, 2017: Journal of Psychiatric and Mental Health Nursing
https://www.readbyqxmd.com/read/29152537/halfhearted-action-and-control
#7
Joshua Shepherd
Some of the things we do intentionally we do halfheartedly. I develop and defend an account of halfheartedness with respect to action on which one is halfhearted with respect to an action A if one's overall motivation to A is weak. This requires getting clear on what it is to have some level of overall motivation with respect to an action, and on what it means to say one's overall motivation is weak or strong. After developing this account, I defend the claim that one key functional expression of halfhearted action is the possession of impaired control over the action in question...
2017: Ergo: An Open Access Journal of Philosophy
https://www.readbyqxmd.com/read/29149257/eleven-telomere-epigenetic-clock-and-biomarker-composite-quantifications-of-biological-aging-do-they-measure-the-same-thing
#8
Daniel W Belsky, Terrie E Moffitt, Alan A Cohen, David L Corcoran, Morgan E Levine, Joseph A Prinz, Jonathan Schaefer, Karen Sugden, Benjamin Williams, Richie Poulton, Avshalom Caspi
The geroscience hypothesis posits that therapies to slow biological processes of aging can prevent disease and extend healthy years of life. To test such "gero-protective" therapies in humans, outcome measures are needed that can assess extension of disease-free lifespan. This need has spurred development of different methods to quantify biological aging. But different methods have not been systematically compared in the same humans. We implemented seven methods to quantify biological aging using repeated-measures physiological and genomic data in 964 middle-aged humans in the Dunedin Study...
November 15, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29148049/editorial-what-is-depression
#9
EDITORIAL
Argyris Stringaris
'Depression is a common, debilitating, and potentially lethal disorder.' This is a standard opening to many a scientific paper on depression. And it is often followed by some very grim statistics. Over 300 million people in the world are estimated to live with depression, and the disorder is ranked by WHO as the single largest contributor to global disability. Most worryingly, adolescents with major depressive disorder are up to 30 times more likely to commit suicide. Yet, what exactly is depression? Do all 300 million depressed people in the world suffer from the same thing, with the same aetiology? Is depression one disorder that comes in different shades of severity or is it best thought of as heterogeneous mix of problems that we have given one common name to? And, more practically, should we be treating all depression in similar ways?...
December 2017: Journal of Child Psychology and Psychiatry, and Allied Disciplines
https://www.readbyqxmd.com/read/29145906/-a-rose-is-a-rose-is-a-rose
#10
C H Vinkers
Over a century ago in 1913, the poet Gertrude Stein wrote these famous words: sometimes things are just what they are. There has been a recent debate centred around the question whether or not schizophrenia exists. Is there a brain disease that can be called schizophrenia? What difference does it make to patients how we define schizophrenia? This editorial explores said questions, concluding that there is still much to be done to improve the recovery of patients diagnosed with disorders of the schizophrenia spectrum...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/29122382/using-biological-insight-and-pragmatism-when-thinking-about-pseudoreplication
#11
REVIEW
Nick Colegrave, Graeme D Ruxton
Pseudoreplication is controversial across experimental biology. Researchers in the same field can disagree on whether a given study suffers from pseudoreplication and on to what extent any pseudoreplication undermines the value of a study. A recent survey indicated that concerns about pseudoreplication can strongly impact peer review of manuscripts submitted for publication. Here we explore controversies around pseudoreplication, identify issues requiring resolution, and in each case offer a resolution. We emphasise that having non-independence in data points and pseudoreplicating are not the same thing...
November 6, 2017: Trends in Ecology & Evolution
https://www.readbyqxmd.com/read/29108485/minimising-the-risk-of-mycobacterium-chimaera-infection-during-cardiopulmonary-bypass-by-the-removal-of-heater-cooler-units-from-the-operating-room
#12
Thomas A Barker, Uday Dandekar, Nina Fraser, Lincoln Dawkin, Paul Sweeney, Fraser Heron, Jacqui Simmons, Jitendra Parmar
INTRODUCTION: Mycobacterium chimaera ( M. chimaera) is a recently characterised bacterium that can cause life-threatening infections in small numbers of patients who undergo cardiopulmonary bypass during cardiac surgery. The likely mode of transmission is thought to occur through aerosolisation from contaminated water reservoirs. The airborne bacteria then contaminate the surgical field, leading to an infection months or even years later. The preferred practical solution to disrupt the transmission of these airborne bacteria to the patient is to remove the heater-cooler units (HCUs) from the operating room (OR)...
November 1, 2017: Perfusion
https://www.readbyqxmd.com/read/29097997/the-more-the-better-do-the-right-thing-for-natural-killer-immunotherapy-in-acute-myeloid-leukemia
#13
REVIEW
Sarah Parisi, Mariangela Lecciso, Darina Ocadlikova, Valentina Salvestrini, Marilena Ciciarello, Dorian Forte, Giulia Corradi, Michele Cavo, Antonio Curti
Natural killer (NK) cells are circulating CD3(-) lymphocytes, which express CD56 or CD16 and an array of inhibitory receptors, called killer-immunoglobulin-like receptors (KIRs). Alloreactive KIR-ligand mismatched NK cells crucially mediate the innate immune response and have a well-recognized antitumor activity. Adoptive immunotherapy with alloreactive NK cells determined promising clinical results in terms of response in acute myeloid leukemia (AML) patients and several data demonstrated that response can be influenced by the composition of NK graft...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29073313/things-we-do-for-no-reason-echocardiogram-in-unselected-patients-with-syncope
#14
Charles L Madeira, Michael J Craig, Andrew Donohoe, John R Stephens
Syncope is a common cause of emergency department visits and hospitalizations. Echocardiogram is frequently used as a diagnostic tool in the evaluation of syncope, performed in 39% to 91% of patients. The diagnostic yield of echocardiogram for detecting clinically important abnormalities in patients with a normal history, physical examination, and electrocardiogram (ECG), however, is extremely low. In contrast, echocardiograms performed on patients with syncope with a positive cardiac history, abnormal examination, and/or ECG identify an abnormality in up to 29% of cases, though these abnormalities are not always defi nitively the cause of symptoms...
October 18, 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29062526/learning-to-work-together-lessons-from-a-reflective-analysis-of-a-research-project-on-public-involvement
#15
A Howe, E Mathie, D Munday, M Cowe, C Goodman, J Keenan, S Kendall, F Poland, S Staniszewska, P Wilson
PLAIN ENGLISH SUMMARY: Patient and public involvement (PPI) in research is very important, and funders and the NHS all expect this to happen. What this means in practice, and how to make it really successful, is therefore an important research question. This article analyses the experience of a research team using PPI, and makes recommendations on strengthening PPI in research. There were different PPI roles in our study - some people were part of the research team: some were on the advisory group; and there were patient groups who gave specific feedback on how to make research work better for their needs...
2017: Research Involvement and Engagement
https://www.readbyqxmd.com/read/29042022/state-of-the-field-paper-tools
#16
REVIEW
Boris Jardine
Paper occupies a special place in histories of knowledge. It is the substrate of communication, the stuff of archives, the bearer of marks that make worlds. For the early-modern period in particular we now have a wealth of studies of 'paper tools', of the ways in which archives were assembled and put to use, of the making of lists and transcribing of observations, and so on. In other fields, too, attention has turned to the materiality of information. How far is it possible to draw a stable methodology out of the insights of literary and book historians, bibliographers, anthropologists, and those working in media studies? Do these diverse fields in fact refer to the same thing when they talk of paper, its qualities, affordances and limitations? In attempting to answer these questions, the present essay begins in the rich territory of early-modern natural philosophy - but from there opens out to take in recent works in a range of disciplines...
August 2017: Studies in History and Philosophy of Science
https://www.readbyqxmd.com/read/29034806/exploring-the-east-west-divide-in-prevalence-of-affective-disorder-a-case-for-cultural-differences-in-coping-with-negative-emotion
#17
June De Vaus, Matthew J Hornsey, Peter Kuppens, Brock Bastian
Lifetime rates of clinical depression and anxiety in the West tend to be approximately 4 to 10 times greater than rates in Asia. In this review, we explore one possible reason for this cross-cultural difference, that Asian cultures think differently about emotion than do Western cultures and that these different systems of thought help explain why negative affect does not escalate into clinical disorder at the same rate. We review research from multiple disciplines-including cross-cultural psychology, social cognition, clinical psychology, and psychiatry-to make the case that the Eastern holistic principles of contradiction (each experience is associated with its opposite), change (the world exists in a state of constant flux), and context (the interconnectedness of all things) fundamentally shape people's experience of emotions in different cultures...
October 1, 2017: Personality and Social Psychology Review
https://www.readbyqxmd.com/read/29030309/hearing-the-voice-of-the-resident-in-long-term-care-facilities-an-internationally-based-approach-to-assessing-quality-of-life
#18
John N Morris, Anja Declercq, John P Hirdes, Harriet Finne-Soveri, Brant E Fries, Mary L James, Leon Geffen, Vahe Kehyayan, Kai Saks, Katarzyna Szczerbińska, Eva Topinkova
OBJECTIVES: interRAI launched this study to introduce a set of standardized self-report measures through which residents of long-term care facilities (LTCFs) could describe their quality of life and services. This article reports on the international development effort, describing measures relative to privacy, food, security, comfort, autonomy, respect, staff responsiveness, relationships with staff, friendships, and activities. First, we evaluated these items individually and then combined them in summary scales...
October 10, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28992277/advances-in-abscission-signaling
#19
O Rahul Patharkar, John C Walker
Abscission is a process in plants for shedding unwanted organs such as leaves, flowers, fruits, or floral organs. Shedding of leaves in the fall is the most visually obvious display of abscission in nature. The very shape plants take is forged by the processes of growth and abscission. Mankind manipulates abscission in modern agriculture to do things such as prevent pre-harvest fruit drop prior to mechanical harvesting in orchards. Abscission occurs specifically at abscission zones that are laid down as the organ that will one day abscise is developed...
September 7, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/28961118/advanced-boundary-electrode-modeling-for-tes-and-parallel-tes-eeg
#20
S Pursiainen, B Agsten, S Wagner, C H Wolters
This paper explores advanced electrode modeling in the context of separate and parallel transcranial electrical stimulation (tES) and electroencephalography (EEG) measurements.We focus on boundary condition based approaches that do not necessitate adding auxiliary elements, e.g. sponges, to the computational domain. In particular, we investigate the complete electrode model (CEM) which incorporates a detailed description of the skin-electrode interface including its contact surface, impedance and normal current distribution...
September 28, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
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