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Guo ping shi

Yi Wang, Jian-Ning Zhang, Wei Hu, Ji-Jun Li, Jia-Xuan Zhou, Jian-Ping Zhang, Guo-Feng Shi, Ping He, Zai-Wang Li, Ming Li
Introduction: Subjective chronic tinnitus is a common medical syndrome with a high frequency of cognitive impairment; however, the characteristics of cognitive impairment in chronic tinnitus are poorly understood. Investigating the scope of cognitive impairment across the severity spectrum of tinnitus patients may shed light on the issue. Methods: A consecutive series of 207 subjective chronic tinnitus patients were classified into mild tinnitus group ( n  = 95) and severe tinnitus group ( n  = 112) by THI score (the cutoff THI scores were 37/38)...
March 2018: Brain and Behavior
Wei Jiang, Min Guo, Min Gong, Li Chen, Yang Bi, Yun Zhang, Yuan Shi, Ping Qu, Youxue Liu, Jie Chen, Tingyu Li
Our previous studies demonstrated that vitamin A deficiency (VAD) can impair the postnatal cognitive function of rats by damaging the hippocampus. The present study examined the effects of retinoic acid (RA) on apoptosis induced by hypoxic-ischemic damage in vivo and in vitro, and investigated the possible signaling pathway involved in the neuroprotective anti-apoptotic effects of RA. Flow cytometry, immunofluorescence staining and behavioral tests were used to evaluate the neuroprotective and anti-apoptotic effects of RA...
March 13, 2018: Molecular Brain
Yan-Ping Zhang, Hai-Feng Liu, Hai-Long Hu, Rui-Shi Xie, Guo-Hua Ma, Ji-Chuan Huo, Hai-Bin Wang
LaCoO3 epitaxial films were grown on (100), (110) and (111) oriented LaAlO3 substrates by the polymer-assisted deposition method. Crystal structure measurement and cross-section observation indicate that all the LaCoO3 films are epitaxially grown in accordance with the orientation of LaAlO3 substrates, with biaxial compressive strain in the ab plane. Owing to the different strain directions of CoO6 octahedron, the mean Co-O bond length increases by different amounts in (100), (110) and (111) oriented films compared with that of bulk LaCoO3 , and the (100) oriented LaCoO3 has the largest increase...
February 2018: Royal Society Open Science
Yong Liu, Kai-Hong Chen, Shi-Qun Chen, Li-Ling Chen, Chong-Yang Duan, Kun Wang, Xiao-Sheng Guo, Hua-Long Li, Wei-Jie Bei, Kai-Yan Lin, Ping-Yan Chen, Ying Xian, Ning Tan, Ying-Ling Zhou, Qing-Shan Geng, Ji-Yan Chen
[This corrects the article DOI: 10.18632/oncotarget.19034.].
February 6, 2018: Oncotarget
Guang-Jiang Shi, Guang-Rui Shi, Jia-Yin Zhou, Wen-Jin Zhang, Chen-Ying Gao, Ya-Ping Jiang, Zhen-Guo Zi, Hai-Hong Zhao, Yong Yang, Jian-Qiang Yu
Diabetes mellitus (DM) is a major endocrine metabolic disease and is marked by a lack of insulin. The complication of DM is one of the most difficult problems in medicine. The initial translational studies revealed that growth factors have a major role in integrating tissue physiology and in embryology as well as in growth, maturation and tissue repair. In some tissues affected by diabetes, growth factors are induced by a relative deficit or excess. Fibroblast growth factor 21 (FGF21) is a promising regulator of glucose and lipid metabolism with multiple beneficial effects including hypoglycemic and lipid-lowering...
March 1, 2018: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
Yong-Jie Liu, Shi-Qing Gao, Yi-Miao Tang, Jie Gong, Xiao Zhang, Yong-Bo Wang, Li-Ping Zhang, Ren-Wei Sun, Quan Zhang, Zhao-Bo Chen, Xiang Wang, Cai-Juan Guo, Sheng-Quan Zhang, Feng-Ting Zhang, Jian-Gang Gao, Hui Sun, Wei-Bing Yang, Wei-Wei Wang, Chang-Ping Zhao
Transcriptome analysis was carried out for wheat seedlings and spikes from hybrid Jingmai 8 and both inbred lines to unravel mechanisms underlying heterosis. Heterosis, known as one of the most successful strategies for increasing crop yield, has been widely exploited in plant breeding systems. Despite its great importance, the molecular mechanism underlying heterosis remains elusive. In the present study, RNA sequencing (RNA-seq) was performed on the seedling and spike tissues of the wheat (Triticum aestivum) hybrid Jingmai 8 (JM8) and its homozygous parents to unravel the underlying mechanisms of wheat heterosis...
March 5, 2018: Planta
Kai-Bo Chen, Yi-Qiao Lu, Jian-De Chen, Di-Ke Shi, Zhi-Hui Huang, Yi-Xiong Zheng, Xiao-Li Jin, Zhe-Fang Wang, Wei-Dong Zhang, Yi Huang, Zhi-Wei Wu, Guo-Ping Zhang, Hang Zhang, Ying-Hao Jiang, Li Chen
AIM: To investigate the efficacy and safety of transcutaneous electroacupuncture (TEA) to alleviate postoperative ileus (POI) after gastrectomy. METHODS: From April 2014 to February 2017, 63 gastric cancer patients were recruited from the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China. After gastrectomy, the patients were randomly allocated to the TEA ( n = 33) or control ( n = 30) group. The patients in the TEA group received 1 h TEA on Neiguan (ST36) and Zusanli (PC6) twice daily in the morning and afternoon until they passed flatus...
February 27, 2018: World Journal of Gastrointestinal Surgery
Ke Wang, Yansen Bai, Shi Chen, Jiao Huang, Jing Yuan, Weihong Chen, Ping Yao, Xiaoping Miao, Youjie Wang, Yuan Liang, Xiaomin Zhang, Meian He, Handong Yang, Qingyi Wei, Huan Guo, Sheng Wei
Although serum tumor biomarkers alpha-fetoprotein (AFP), carbohydrate antigen 19-9 (CA19-9) and carcinoembryonic antigen (CEA) have been used in digestive cancer risk prediction, the prediction efficiency remains unsatisfactory. The aim of this study was to evaluate whether genetic correction could improve the efficiency of these biomarkers for prediction of digestive cancer risk. We conducted a prospective analysis in 9,808 healthy individuals based on a cohort study in the elderly Chinese population. The genotypes of reported single nucleotide polymorphisms (SNPs) associated with serum AFP, CA19-9 and CEA were used to estimate the genetic corrected levels of these markers...
January 26, 2018: Oncotarget
Yi-Ping Hou, Xue-Wei Mao, Shi-Peng Lin, Xiu-Shi Song, Ya-Bing Duan, Jian-Xin Wang, Ming-Guo Zhou
Pyraziflumid is a novel member of succinate dehydrogenase inhibitor fungicides (SDHI). In this study, baseline sensitivity of Sclerotinia sclerotiorum (Lib.) de Bary to pyraziflumid was determined using 105 strains collected during 2015 and 2017 from different geographical regions in Jiangsu Province of China, and the average EC50 value was 0.0561 (±0.0263)μg/ml for mycelial growth. There was no cross-resistance between pyraziflumid and the widely used fungicides carbendazim, dimethachlon and the phenylpyrrole fungicide fludioxonil...
February 2018: Pesticide Biochemistry and Physiology
Changzheng Wang, Yang Zhang, Yajun Zhang, Ping Xu, Cuimin Feng, Tao Chen, Tao Guo, Fengnan Yang, Qiang Wang, Jingxiao Wang, Mengtong Shi, Louzhen Fan, Shaowei Chen
Highly ordered hierarchical Pt and PtNi nanowire arrays were prepared by using CdS hierarchical nanowire arrays (HNWAs) as sacrificial templates and demonstrated high electrochemical active surface areas. For the resulting Pt HNWAs sample, the peak current for methanol oxidation at +0.74 V was almost one order of magnitude higher than that of Pt solid nanowire arrays (SNWAs) prepared in a similar manner but without the use of CdS template, and the addition of a Ni cocatalyst effectively enhanced the tolerance against CO poisoning...
February 23, 2018: ACS Applied Materials & Interfaces
Xue-Wei Mao, Jiao-Sheng Li, Ya-Li Chen, Xiu-Shi Song, Ya-Bing Duan, Jian-Xin Wang, Chang-Jun Chen, Ming-Guo Zhou, Yi-Ping Hou
In the current study, sensitivity distribution of Sclerotinia sclerotiorum populations to fluazinam was determined using 103 strains collected from the fields of Jiangsu Province of China in 2016-2017 and the resistance risk of fluazinam was assessed. The average EC50 (50% effective concentration) values and MIC (minimum inhibitory concentration) values of 103 S. sclerotiorum strains against fluazinam were 0.0073±0.0045μg/ml and <0.3μg/ml for mycelial growth, respectively. Nine mutants with low resistance level were obtained from wild type sensitive strains exposed on PDA medium amended with fluazinam and the resistance was stable after their ten transfers on PDA without the fungicide...
January 2018: Pesticide Biochemistry and Physiology
Sun-Ting Ma, Guo-Jie Ding, Xue-Wei Huang, Zi-Wei Wang, Li Wang, Mei-Ling Yu, Wen Shi, Yan-Ping Jiang, Li-Jie Tang, Yi-Gang Xu, Yi-Jing Li
PURPOSE: Avian colibacillosis is responsible for economic losses to poultry producers worldwide. To combat this, we aimed to develop an effective oral vaccine for chicken against O78 avian pathogenic Escherichia coli (APEC) infection through a Lactobacillus delivery system. METHODOLOGY: Eight Lactobacillus strains isolated from the intestines of broiler chickens were evaluated based on their in vitro adherence ability to assess their potential as a delivery vector...
January 19, 2018: Journal of Medical Microbiology
Xue Gao, Yong-Yi Yuan, Qiong-Fen Lin, Jin-Cao Xu, Wei-Qian Wang, Yue-Hua Qiao, Dong-Yang Kang, Dan Bai, Feng Xin, Sha-Sha Huang, Shi-Wei Qiu, Li-Ping Guan, Yu Su, Guo-Jian Wang, Ming-Yu Han, Yi Jiang, Han-Kui Liu, Pu Dai
Background Hereditary sensorineural hearing loss is a genetically heterogeneous disorder. Objectives This study was designed to explore the genetic etiology of deafness in a large Chinese family with autosomal dominant, nonsyndromic, progressive sensorineural hearing loss (ADNSHL). Methods Whole exome sequencing and linkage analysis were performed to identify pathogenic mutation. Inner ear expression of Ifnlr1 was investigated by immunostaining in mice. ifnlr1 Morpholino knockdown Zebrafish were constructed to explore the deafness mechanism...
February 16, 2018: Journal of Medical Genetics
Feng Chen, Yaqiong Jin, Lin Feng, Jie Zhang, Jun Tai, Jin Shi, Yongbo Yu, Jie Lu, Shengcai Wang, Xin Li, Ping Chu, Shujing Han, Shujun Cheng, Yongli Guo, Xin Ni
Background: Papillary thyroid carcinoma (PTC) is one of the most frequent malignancies of the endocrine system, whose mechanisms of pathogenesis, progression and prognosis are still far from being clearly elucidated. Despite an increasing body of evidences highlights ribosome biogenesis regulator homolog (RRS1) as a ribosome biogenesis protein in yeast and plants, little is known about human RRS1 function. Methods: Proliferation, cell cycle and apoptosis of PTC cells were assessed following the knockdown of RRS1 expression though MTT, colony formation assay, and flow cytometry...
2018: Cancer Cell International
Teng Ma, Deyi Lu, Yin-Sheng Zhu, Xue-Feng Chu, Yong Wang, Guo-Ping Shi, Zheng-Dong Wang, Li Yu, Xiao-Yan Jiang, Xiao-Feng Wang
Objective: To examine the associations of the actinin alpha 3 gene (ACTN3) R577X polymorphism with physical performance and frailty in an older Chinese population. Methods: Data from 1,463 individuals (57.8% female) aged 70-87 years from the Rugao Longevity and Ageing Study were used. The associations between R577X and timed 5-m walk, grip strength, timed Up and Go test, and frailty index (FI) based on deficits of 23 laboratory tests (FI-Lab) were examined. Analysis of variance and linear regression models were used to evaluate the genetic effects of ACTN3 R577X on physical performance and FI-Lab...
February 13, 2018: Age and Ageing
Liang-Xing Fang, Xing-Ping Li, Guo-Hui Deng, Shu-Min Li, Run-Shi Yang, Zuo-Wei Wu, Xiao-Ping Liao, Jian Sun, Ya-Hong Liu
We report a novel fusion plasmid pP2-3T co-integrating ST3-IncHI2 with IncFII plasmid backbone mediating multidrug resistance and virulence. Phylogenetic analysis and comparative genomic revealed that pP2-3T and other MDR ST3-IncHI2 plasmids clustered together representing a unique IncHI2 lineage that exhibited high conservation in backbones of plasmid, but possessed highly genetic plasticity in variable regions via acquiring numerous ARGs and fusing with other plasmids. Surveillance studies should be taken to monitor multiresistance IncHI2 plasmids among Enterobacteriaceae...
February 5, 2018: Antimicrobial Agents and Chemotherapy
Jing-Xiu Li, Yang Li, Shu-Jun Yan, Bai-He Han, Zhao-Yan Song, Wei Song, Shi-Hao Liu, Ji-Wei Guo, Shuo Yin, Ye-Ping Chen, De-Jun Xia, Xin Li, Xue-Qi Li, En-Ze Jin
A challenge for antithrombotic treatment is patients who present with atrial fibrillation (AF) and acute coronary syndrome, particularly in patients who have undergone coronary percutaneous intervention with stenting (PCIS). In the present study, a total of nine observational trials published prior to July 2017 that investigated the effects of dual antiplatelet therapy (DAPT; aspirin + clopidogrel) and triple oral antithrombotic therapy (TOAT; DAPT + warfarin) among patients with AF concurrent to PCIS were collected from the Medline, Cochrane and Embase databases and conference proceedings of cardiology, gastroenterology and neurology meetings...
February 2018: Biomedical Reports
Yu-Hui Li, Ya-Ping Gao, Jie Dong, Lian-Jie Shi, Xiao-Lin Sun, Ru Li, Xue-Wu Zhang, Yu Liu, Li Long, Jing He, Qun-Jie Zhong, Eric Morand, Guang Yang, Zhan-Guo Li
BACKGROUND: Sjögren's syndrome (SS) is a primary autoimmune disease (pSS) or secondarily associated with other autoimmune diseases (sSS). The mechanisms underlying immune dysregulation in this syndrome remain unknown, and clinically it is difficult to diagnose owing to a lack of specific biomarkers. METHODS: We extracted immunoglobulins (Igs) from the sera of patients with sSS associated with rheumatoid arthritis (RA) and used them to screen a phage display library of peptides with random sequences...
February 12, 2018: Arthritis Research & Therapy
Xin-Wei Li, Qiu-Shi Xu, Ren-He Zhang, Wei Yang, Yu Li, Yu-Ming Zhang, Yu Tian, Min Zhang, Zhe Wang, Guo-Wen Liu, Cheng Xia, Xiao-Bing Li
BACKGROUND: The natural incidence of left displacement of abomasum (LDA) in dairy cows was high. The diagnosis of LDA usually relies on characteristic physical exam findings but that transabdominal ultrasound is a useful technique that has been applied to the diagnosis of gastrointestinal diseases of dairy cows in equivocal cases. METHODS: Forty dairy cows with LDA were clinically and ultrasonographically examined to determine the position and the echogenic property of the abomasum...
February 12, 2018: BMC Veterinary Research
Dong Guo, Zi-Ping Yang, Hui-Liang Li, Ying Wang, Jia-Hong Zhu, Shi-Qing Peng
Hevea brasiliensis is a key commercial natural rubber (cis 1,4-polyisoprene) source. In H. brasiliensis, rubber transferase is responsible for cis-1,4-polymerization of isoprene units from isopentenyl diphosphate and implicated in natual rubber yield. Little is known about the regulatory mechanism of rubber transferase gene at molecular levels. Here, we showed that 5'UTR intron of the promoter of rubber transferase gene (HRT2) suppresses the expression of HRT2. A Hevea RING zinc finger protein (designated as HbRZFP1) was able to interact specifically with the HRT2 promoter to down-regulate its transcription in vivo...
February 8, 2018: Journal of Experimental Botany
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