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Pediatric ADHD

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https://www.readbyqxmd.com/read/28631372/patient-and-provider-characteristics-related-with-prescribing-of-adhd-medication-nationwide-health-insurance-claims-database-study-in-korea
#1
Inmyung Song, Mo Se Lee, Eui-Kyung Lee, Ju-Young Shin
BACKGROUND: Little is known about the association between prescribing of attention deficit hyperactivity disorder (ADHD) medication and the patient's age, gender, and type of medical institution in Asia region. INTRODUCTION: This study investigates the prevalence and factors of diagnosis and pharmacological treatment of ADHD in the pediatric population. METHODS: Using the Korea Health Insurance database, study participants were identified as pediatric patients (≤17 years) with at least 1 diagnosis of ADHD (ICD-10, F90) from January 1, 2007 to December 31, 2011...
June 20, 2017: Asia-Pacific Psychiatry: Official Journal of the Pacific Rim College of Psychiatrists
https://www.readbyqxmd.com/read/28616427/specific-genes-associated-with-adverse-events-of-methylphenidate-use-in-the-pediatric-population-a-systematic-literature-review
#2
REVIEW
Beinta Joensen, Morten Meyer, Lise Aagaard
The aim of this study was to review empirical studies examining associations between candidate genes and adverse events (AEs) from methylphenidate (MPH) use in children and adolescents. The PubMed, EMBASE, CINAHL, and Web of Science databases were searched from their inception until March 2017. We included empirically based articles on pharmacogenetic studies in 0-17-year-old patients that investigated associations between specific candidate genes, their polymorphisms, and reported AEs. We extracted information about study design, setting, type of AE reporter, studied genes and their polymorphisms, age and gender, administered doses, method of genotyping, outcome measures, and main findings...
April 2017: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/28604931/motor-vehicle-crash-risk-among-adolescents-and-young-adults-with-attention-deficit-hyperactivity-disorder
#3
Allison E Curry, Kristina B Metzger, Melissa R Pfeiffer, Michael R Elliott, Flaura K Winston, Thomas J Power
Importance: Attention-deficit/hyperactivity disorder (ADHD) often persists into adolescence, when motor vehicle crash risk peaks. We know little about when adolescents with ADHD get licensed and, once they do, the extent to which they have increased crash risk compared with adolescents without ADHD. Objectives: To examine the association between ADHD and both driver licensing and crash involvement and whether it varies by sex, licensing age, and/or being prescribed ADHD medication at licensure...
June 12, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28588625/change-in-bmi-after-radioactive-iodine-ablation-for-graves-disease
#4
Melinda Chen, Matthew Lash, Todd Nebesio, Erica Eugster
BACKGROUND: We aimed to determine the extent of post-treatment weight gain that occurs in pediatric patients in the first year following radioactive iodine (RAI) therapy for Graves disease (GD) and its relationship to clinical characteristics. METHODS: A retrospective chart review of patients receiving RAI therapy for GD between 1998-2015 was performed. Change in BMI SDS (∆BMI SDS) from baseline to one year after treatment was determined. We also investigated whether individual clinical and/or biochemical factors were associated with the weight trajectory in these patients...
2017: International Journal of Pediatric Endocrinology
https://www.readbyqxmd.com/read/28587507/adhd-is-comorbid-to-migraine-in-childhood-a-population-based-study
#5
Marco Antônio Arruda, Renato Arruda, Vincenzo Guidetti, Marcelo Eduardo Bigal
OBJECTIVE: Recurrent headaches and ADHD are prevalent in the pediatric population. Herein, we assess if ADHD is comorbid to headaches overall, to headache subtypes (e.g., migraine), and to headache frequency. METHOD: Informed consent and analyzable data were obtained for 5,671 children aged 5 to 12 years (65.9% of the target sample). Parents and teachers were interviewed using validated questionnaires based on the Diagnostic and Statistical Manual of Mental Disorders (5th ed...
June 1, 2017: Journal of Attention Disorders
https://www.readbyqxmd.com/read/28577701/challenges-of-developing-an-observable-parent-reported-measure-a-qualitative-study-of-functional-impact-of-adhd-in-children
#6
Louis S Matza, Mary Kay Margolis, Linda S Deal, Kimberly F Farrand, M Haim Erder
BACKGROUND: Informant-reported outcome measures, usually completed by parents, are often administered in pediatric clinical trials with the intention of collecting data to support claims in a medical product label. Recently, there has been an emphasis on limiting these measures to observable content, as recommended in the US Food and Drug Administration guidance on patient-reported outcomes. This qualitative study explores the concept of observability using the example of childhood attention deficit/hyperactivity disorder (ADHD)...
June 2017: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/28554265/secondary-attention-deficit-hyperactivity-disorder-following-perinatal-and-childhood-stroke-impact-on-cognitive-and-academic-outcomes
#7
Tricia S Williams, Samantha D Roberts, Andrea M Coppens, Jennifer Crosbie, Nomazulu Dlamini, Robyn Westmacott
This cross-sectional retrospective clinical research study examines a large group of children followed within a pediatric stroke program and a developmental attention-deficit/hyperactivity disorder (ADHD) clinic at the Hospital for Sick Children, between May 2004 and June 2016. All children with a history of stroke who participated in a neuropsychological assessment between the ages of 4 and 18 years were considered for inclusion. From a sample of 275 participants with a history of stroke, 36 children (13...
May 30, 2017: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
https://www.readbyqxmd.com/read/28545753/specific-components-of-pediatricians-medication-related-care-predict-attention-deficit-hyperactivity-disorder-symptom-improvement
#8
Jeffery N Epstein, Kelly J Kelleher, Rebecca Baum, William B Brinkman, James Peugh, William Gardner, Phil Lichtenstein, Joshua M Langberg
OBJECTIVE: The development of attention-deficit/hyperactivity disorder (ADHD) care quality measurements is a prerequisite to improving the quality of community-based pediatric care of children with ADHD. Unfortunately, the evidence base for existing ADHD care quality metrics is poor. The objective of this study was to identify which components of ADHD care best predict patient outcomes. METHOD: Parents of 372 medication-naïve children in grades 1 to 5 presenting to their community-based pediatrician (N = 195) for an ADHD-related concern and who were subsequently prescribed ADHD medication were identified...
June 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28544732/similar-familial-underpinnings-for-full-and-subsyndromal-pediatric-bipolar-disorder-a-familial-risk-analysis
#9
Janet Wozniak, Mai Uchida, Stephen V Faraone, Maura Fitzgerald, Carrie Vaudreuil, Nicholas Carrellas, Jacqueline Davis, Rebecca Wolenski, Joseph Biederman
OBJECTIVES: To examine the validity of subthreshold pediatric bipolar I disorder (BP-I), we compared the familial risk for BP-I in the child probands who had either full BP-I, subthreshold BP-I, ADHD, or were controls that neither had ADHD nor bipolar disorder. METHODS: BP-I probands were youth aged 6-17 years meeting criteria for BP-I, full (N=239) or subthreshold (N=43), and also included were their first-degree relatives (N=687 and N=120, respectively). Comparators were youth with ADHD (N=162), controls without ADHD or bipolar disorder (N=136), and their first-degree relatives (N=511 and N=411, respectively)...
May 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/28516426/characterization-of-medication-use-in-a-multicenter-sample-of-pediatric-inpatients-with-autism-spectrum-disorder
#10
Logan K Wink, Ernest V Pedapati, Ryan Adams, Craig A Erickson, Kahsi A Pedersen, Eric M Morrow, Desmond Kaplan, Matthew Siegel
Nearly 11% of youth with Autism Spectrum Disorder (ASD) undergo psychiatric hospitalization, and 65% are treated with psychotropic medication. Here we characterize psychotropic medication usage in subjects enrolled in the Autism Inpatient Collection. Participant psychotropic medication usage rates topped 90% at admission and discharge, though there was a decline at 2-month follow-up. Antipsychotics, ADHD medications, and sleep aids were the most commonly reported classes of medications. The impact of age, gender, and non-verbal IQ on medication usage rates was minimal, though age and IQ may play a role in prescribing practices...
May 17, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28493861/maternal-pre-pregnancy-obesity-and-neuropsychological-development-in-pre-school-children-a-prospective-cohort-study
#11
Maribel Casas, Joan Forns, David Martínez, Mònica Guxens, Ana Fernandez-Somoano, Jesus Ibarluzea, Nerea Lertxundi, Mario Murcia, Marisa Rebagliato, Adonina Tardon, Jordi Sunyer, Martine Vrijheid
BackgroundMaternal pre-pregnancy obesity may impair infant neuropsychological development, but it is unclear whether intrauterine or confounding factors drive this association.MethodsWe assessed whether maternal pre-pregnancy obesity was associated with neuropsychological development in 1,827 Spanish children. At 5 years, cognitive and psychomotor development was assessed using McCarthy Scales of Children's Abilities, attention deficit hyperactivity disorder (ADHD) symptoms using the Criteria of Diagnostic and Statistical Manual of Mental Disorders, and autism spectrum disorder symptoms using the Childhood Asperger Syndrome Test...
June 7, 2017: Pediatric Research
https://www.readbyqxmd.com/read/28490997/adhd-in-pediatric-epilepsy-fact-or-fiction
#12
COMMENT
Rochelle Caplan
No abstract text is available yet for this article.
March 2017: Epilepsy Currents
https://www.readbyqxmd.com/read/28490400/association-of-pediatric-allergic-rhinitis-with-the-ratings-of-attention-deficit-hyperactivity-disorder
#13
Bohai Feng, Haiyong Jin, Haijie Xiang, Bangliang Li, Xiuxiu Zheng, Ruru Chen, Yunbin Shi, Si Chen, Bobei Chen
BACKGROUND: Allergic rhinitis (AR) is currently the most prevalent allergic disease in children and adolescents. OBJECTIVE: Surveys conducted by population-based studies of East Asia revealed an increased prevalence of behavioral disorders in patients with AR. Thus, in this study, we explored the prevalence of attention-deficit/hyperactivity disorder (ADHD) in pediatric patients with AR. METHODS: A total of 333 children (6-12 years of age) with AR and a total of 322 age-matched controls were included in this study...
May 1, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/28490210/adhd-symptoms-and-quality-of-life-across-a-12-month-period-in-children-with-adhd-a-longitudinal-study
#14
Melissa Mulraney, Rebecca Giallo, Emma Sciberras, Kate Lycett, Fiona Mensah, David Coghill
OBJECTIVE: To describe the relationship between ADHD symptom severity and quality of life (QoL) across three time points over a 12-month period and investigate whether sleep modifies this relationship. METHOD: Children aged 5 to 13 years with ADHD were recruited from 21 pediatric practices across Victoria, Australia ( N = 392). Child QoL (parent-report) and ADHD symptoms (both parent- and teacher-report) were assessed at three time points (0, 6, and 12 months), and sleep was assessed at baseline (parent-report)...
May 1, 2017: Journal of Attention Disorders
https://www.readbyqxmd.com/read/28477289/predictors-of-relapse-or-maintenance-of-response-in-pediatric-and-adult-patients-with-attention-deficit-hyperactivity-disorder-following-discontinuation-of-long-term-treatment-with-atomoxetine
#15
Johannes Thome, Ralf W Dittmann, Laurence L Greenhill, Sarah Lipsius, Yoko Tanaka, Chris Bushe, Rodrigo Escobar, Alexandra N Heinloth, Himanshu Upadhyaya
We identified relapse/maintenance-of-response (MOR) predictors following discontinuation of long-term atomoxetine treatment in pediatric and adult patients with attention-deficit/hyperactivity disorder (ADHD) and assessed correlations between ADHD symptoms and quality of life (QoL). Post hoc analyses of data from two randomized, double-blind, placebo-controlled, phase 3 withdrawal studies in patients with ADHD meeting predefined response criteria before randomization. Study 1: patients (N = 163; 6-15 years) received atomoxetine (1...
May 5, 2017: Attention Deficit and Hyperactivity Disorders
https://www.readbyqxmd.com/read/28466614/do-you-see-it-my-way-the-clinical-evaluation-of-adhd-by-the-different-pediatric-subspecialties
#16
Yael Leitner, Alexis Mitelpunkt, Idit Posner, Noa Vardi
BACKGROUND: Six medical disciplines are responsible for assessment, diagnosis and treatment of people with attention deficiency hyperactivity disorder (ADHD) in Israel: family doctors, pediatricians, adult and child neurologists, adult and child psychiatrists. OBJECTIVES: To investigate differences in ADHD diagnostic practices between three different pediatric subspecialties in the clinical setting in order to establish a common ground for a future unified approach...
November 2016: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28466612/exploring-the-association-between-legg-calv%C3%A3-perthes-disease-and-attention-deficit-hyperactivity-disorder-in-children
#17
Julia Berman, Adi Aran, Tamar Berenstein-Weyel, Ehud Lebel
BACKGROUND: Legg-Calvé-Perthes disease (LCPD) is an idiopathic hip osteonecrosis prevalent in children < age 15 years. The etiology remains incompletely understood, partly because of multiple potential environmental risk factors and partly because of lack of genetic markers. It has been hypothesized that hyperactivity may induce mechanical stress and/or vascular damage at a fragile joint. OBJECTIVES: To assess children with LCPD for markers of attention deficit hyperactivity disorder (ADHD) relative to their unaffected comparably aged siblings to exclude the contribution of hyperactive behavior versus environmental and/or genetic factors in LCPD...
November 2016: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28459608/the-influence-of-comorbid-asthma-on-the-severity-of-symptoms-in-children-with-attention-deficit-hyperactivity-disorder
#18
Adrienne P Borschuk, Casey Rodweller, Cynthia F Salorio
OBJECTIVE: The current study examined the association between asthma and attention-deficit hyperactivity disorder (ADHD) symptoms in a clinical pediatric sample. METHODS: Demographic and neuropsychological data for children with a billing diagnosis of ADHD were extracted from a clinical database. Families completed standard rating scales. Seventy-one patients with a co-morbid asthma diagnosis were identified and matched by age to a group of 71 patients with only ADHD...
May 1, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28451624/tics-in-the-pediatric-population-pragmatic-management
#19
REVIEW
Christos Ganos, Davide Martino, Tamara Pringsheim
BACKGROUND: Primary tic disorders, notably Tourette syndrome, are very common movement disorders in childhood. However, the management of such patients still poses great therapeutic challenges to medical professionals. METHODS: Based on a synthesis of the available guidelines published in Europe, Canada, and the United States, coupled with more recent therapeutic developments, the authors provide a pragmatic guide to aid clinicians in deciding when and how to treat patients who have primary tic disorders...
March 2017: Movement Disorders Clinical Practice
https://www.readbyqxmd.com/read/28441363/mind-body-therapy-for-children-with-attention-deficit-hyperactivity-disorder
#20
REVIEW
Anne Herbert, Anna Esparham
Attention-deficit/hyperactivity disorder (ADHD) is pervasive among the pediatric population and new treatments with minimal adverse effects are necessary to be studied. The purpose of this article is to review current research studying mind-body therapies for treatment of children diagnosed with ADHD. Literature was reviewed pertaining to the effectiveness of movement-based therapies and mindfulness/meditation-based therapies for ADHD. Many positive effects of yoga, Tai Chi, physical activity, and meditation may significantly improve symptoms of ADHD among children...
April 25, 2017: Children
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