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Language impairment

Anna Rita Giovagnoli, Valentina Manfredi, Letizia Schifano, Chiara Paterlini, Annalisa Parente, Fabrizio Tagliavini
Alzheimer's disease (AD) can impair language, but active music therapy (AMT) and memantine (M) can improve communication. This study aimed to clarify whether adding AMT to M may improve language in comparison with drugs alone in patients with moderate AD on stable therapy with acetylcholinesterase inhibitors (AchEI). Forty-five AD patients treated with stable dose of AchEI were randomized to receive AMT plus M 20 mg/day or M 20 mg/day for 24 weeks. The Severe Impairment Battery-Language (SIB-l), SIB, Mini Mental State Examination, Neuropsychiatric Inventory (NPI), Lubben Social Network Scale, Activities of Daily Living, and Instrumental Activities of Daily Living scores at baseline and 12 and 24 weeks assessed language (primary variable) and overall cognitive, psycho-behavior, social, and functional aspects (secondary variables)...
March 17, 2018: Neurological Sciences
Penelope Hannant
A number of studies have evidenced marked difficulties in language in autism spectrum conditions (ASC). Studies have also shown that language and word knowledge are associated with the same area of brain that is also responsible for visual perception in typically developing (TD) individuals. However, in ASC, research suggests word meaning is mapped differently, on to situational sensorimotor components within the brain. Furthermore, motor coordination is associated with communication skills. The current study explores whether motor coordination and visual perception are impaired in children with ASC, and whether difficulties in coordination and visual perception correlate with receptive language levels...
March 14, 2018: Human Movement Science
Giulia Prete, Anita D'Anselmo, Luca Tommasi, Alfredo Brancucci
Transcranial electrical stimulation (tES) has been increasingly adopted to modulate perceptual and cognitive functions, but the effects on auditory perception are still relatively uncharted. Starting from the evidence that a stronger right ear advantage effect (REA) in dichotic listening positively correlates with speech sound processing, the present study was aimed at modulating the REA by means of high-frequency transcranial Random Noise Stimulation (hf-tRNS). Stimulation was applied over the auditory cortex (AC) either unilaterally (Experiment 1, N = 50) or bilaterally (Experiment 2, N = 24) during a verbal dichotic listening task...
March 13, 2018: Brain and Cognition
Ellyn A Riley, Elena Barbieri, Sandra Weintraub, M Marsel Mesulam, Cynthia K Thompson
Prototypical items within a semantic category are processed faster than atypical items within the same category. This typicality effect reflects normal representation and processing of semantic categories and when absent may be reflective of lexical-semantic deficits. We examined typicality effects in individuals with semantic and nonsemantic variants of primary progressive aphasia (PPA; semantic-PPA-S, agrammatic-PPA-G), a neurodegenerative disorder characterized by specific decline in language function, and age-matched controls...
January 1, 2018: American Journal of Alzheimer's Disease and Other Dementias
Alessandro Bosco, Justine Schneider, Donna Maria Coleston-Shields, Lidia Sousa, Martin Orrell
OBJECTIVES: Good interaction with family caregivers helps maintain positive identity in people with dementia. However, research in this area is limited. We aimed to systematically review the dyadic experience of dementia caring. METHOD: We searched on five databases: MedLine, EMBASE, PsycInfo, ASSIA, and CINAHL. Eligible studies employed qualitative or mixed method design, reported the experience of dyads of dementia with no comorbid organic or psychiatric disorders...
March 15, 2018: Aging & Mental Health
Teenu Sanjeevan, David A Rosenbaum, Elina Mainela-Arnold
Purpose: Specific language impairment (SLI) affects many children, but its symptomatology is still being characterized. An emerging view, which challenges the notion that SLI is specific to language, is that SLI may actually reflect a domain-general deficit in procedural learning. We explored an extension of this hypothesis that a core deficit in SLI involves a domain-general problem in planning. Method: We used a dowel-transport task to study the extent to which 13 children with SLI and 14 typically developing (TD) controls (ages over both groups between 8;10 [years;months] and 12;11) would adopt initially awkward grasps that ensured comfortable final grasps when reaching out to move a dowel from 1 position to another (the end-state comfort effect)...
March 14, 2018: Journal of Speech, Language, and Hearing Research: JSLHR
Audra Sterling
Purpose: Some boys with autism spectrum disorder (ASD) and boys with fragile X syndrome and a codiagnosis of ASD (FXS+ASD) have impairments in expressive grammatical abilities. The current study compared grammatical performance in these 2 groups of school-age boys. Method: Thirty-seven boys similar on mean length of utterance participated in the current study (FXS: n = 19, ASD: n = 18). Participants completed an ASD assessment, nonverbal IQ testing, and conversation language samples...
March 14, 2018: Journal of Speech, Language, and Hearing Research: JSLHR
Yi Wang, Jian-Ning Zhang, Wei Hu, Ji-Jun Li, Jia-Xuan Zhou, Jian-Ping Zhang, Guo-Feng Shi, Ping He, Zai-Wang Li, Ming Li
Introduction: Subjective chronic tinnitus is a common medical syndrome with a high frequency of cognitive impairment; however, the characteristics of cognitive impairment in chronic tinnitus are poorly understood. Investigating the scope of cognitive impairment across the severity spectrum of tinnitus patients may shed light on the issue. Methods: A consecutive series of 207 subjective chronic tinnitus patients were classified into mild tinnitus group ( n  = 95) and severe tinnitus group ( n  = 112) by THI score (the cutoff THI scores were 37/38)...
March 2018: Brain and Behavior
Mauro Mancuso, Nele Demeyere, Laura Abbruzzese, Alessio Damora, Valentina Varalta, Fabio Pirrotta, Gabriella Antonucci, Alessandro Matano, Marina Caputo, Maria Giovanna Caruso, Giovanna Teresa Pontiggia, Michela Coccia, Irene Ciancarelli, Pierluigi Zoccolotti
Background: The Oxford Cognitive Screen (OCS) was recently developed with the aim of describing the cognitive deficits after stroke. The scale consists of 10 tasks encompassing five cognitive domains: attention and executive function, language, memory, number processing, and praxis. OCS was devised to be inclusive and un-confounded by aphasia and neglect. As such, it may have a greater potential to be informative on stroke cognitive deficits of widely used instruments, such as the Mini-Mental State Examination (MMSE) or the Montreal Cognitive Assessment, which were originally devised for demented patients...
2018: Frontiers in Neurology
Lozina Shoaib, Sharifullah Khan, Muhammad Azeem Abbas, Ahmad Salman
OBJECTIVE: To mitigate the communication barriers of profound hearing-impaired children by enabling their word articulation ability. METHODS: This pre-experimental pilot study was conducted from September 2016 to March 2017 at the National Special Education Centre for Hearing Impaired Children, Islamabad, Pakistan, and comprised deaf children of both genders aged 5-8 years. A specially designed software application for lip-reading was employed to help the subjects articulate words...
March 2018: JPMA. the Journal of the Pakistan Medical Association
Ondrej Bezdicek, Tommaso Ballarini, Filip Růžička, Jan Roth, Karsten Mueller, Robert Jech, Matthias L Schroeter
Mild cognitive impairment (MCI) affects approximately one-third of non-demented Parkinson's Disease (PD) patients. We aimed at investigating the neural correlates of MCI in PD combining multimodal magnetic resonance imaging (MRI) with large-scale data from the literature. We analyzed 31 PD patients and 30 matched controls. The standard neuropsychological assessment of PD-MCI covered memory, attention, executive functions, language and visuospatial abilities. Following validated criteria, 16 patients were classified as showing MCI...
March 11, 2018: Neuropsychologia
Jong Min Kim, Seung Beom Woo, Zeeihn Lee, Sung Jae Heo, Donghwi Park
RATIONALE: Verbal auditory agnosia is the selective inability to recognize verbal sounds. Patients with this disorder lose the ability to understand language, write from dictation, and repeat words with reserved ability to identify nonverbal sounds. However, to the best of our knowledge, there was no report about verbal auditory agnosia in adult patient with traumatic brain injury. PATIENT CONCERNS: He was able to clearly distinguish between language and nonverbal sounds, and he did not have any difficulty in identifying the environmental sounds...
March 2018: Medicine (Baltimore)
Khetsiwe P Masuku, Munyane Mophosho, Muziwakhe Tshabalala
Background: Aphasia is an acquired impairment in language and in the cognitive processes that underlie language. Aphasia affects the quality of life of the person with aphasia (PWA) and his or her families in various ways in diverse contexts and cultures. It is therefore important that speech language therapists understand how different contextual and cultural factors may mediate experiences. Purpose: The aim of the study was to describe the caregiving experience of female caregivers of PWA residing in Tembisa, a township situated in the east of Johannesburg...
2018: African Journal of Disability
Kimi Estela Kobayashi-Cuya, Ryota Sakurai, Hiroyuki Suzuki, Susumu Ogawa, Toru Takebayashi, Yoshinori Fujiwara
BACKGROUND: Deterioration of hand motor function is a possible risk factor of cognitive impairment in older adults. Despite a growing body of research, a lack of clarity exists regarding the relationships. This review offers a synthesis of existing observational studies evaluating the associations of handgrip strength and hand dexterity with cognitive performance in community-dwelling older adults. METHODS: PubMed, PsycINFO, and ScienceDirect were systematically searched (search dates: 1990-2016), and relevant articles were cross-checked for related and relevant publications...
March 10, 2018: Journal of Epidemiology
Nuria Mendoza Laiz, Sagrario Del Valle Díaz, Natalia Rioja Collado, Javier Gomez-Pilar, Roberto Hornero
BACKGROUND: Dementia is a disease that is constantly evolving in older people. Its diverse symptoms appear with varying degrees of severity affecting the daily life of those who suffer from it. The rate in which dementia progresses depends on different aspects of the treatment, chosen to try to control and slow down the development of the illness. OBJECTIVE: The aim of this study is to assess the effectiveness of cognitive training through a Brain Computer Interface (BCI) and the NeuronUp platform in two age groups whose MMSE is between 18-23 MCI (mild dementia)...
2018: Restorative Neurology and Neuroscience
Zhang Huihong, Wang Pan, Zhang Chunfeng, Wang Yan, Zhang Hui, Cai Li, Zhou Yuying
Objectives: Cognition and speech disorders are the most common symptoms of dementia in neurodegenerative disease. Here, we present a detailed clinical evaluation of a case of logopenic variant of primary progressive aphasia (lv-PPA), an atypical form of Alzheimer disease (AD), including cognitive testing over time, brain imaging, electrophysiology, and tests of olfactory function. Case report: We present the case of a 58-year-old man suffering from progressive language difficulties who was finally diagnosed with lv-PPA...
2018: Translational Neuroscience
Vicky L Ng, Lisa G Sorensen, Estella M Alonso, Emily M Fredericks, Wen Ye, Jeff Moore, Saul J Karpen, Benjamin L Shneider, Jean P Molleston, Jorge A Bezerra, Karen F Murray, Kathleen M Loomes, Philip Rosenthal, Robert H Squires, Kasper Wang, Ronen Arnon, Kathleen B Schwarz, Yumirle P Turmelle, Barbara H Haber, Averell H Sherker, John C Magee, Ronald J Sokol
OBJECTIVES: To assess neurodevelopmental outcomes among participants with biliary atresia with their native liver at ages 12 months (group 1) and 24 months (group 2), and to evaluate variables predictive of neurodevelopmental impairment. STUDY DESIGN: Participants enrolled in a prospective, longitudinal, multicenter study underwent neurodevelopmental testing with either the Bayley Scales of Infant Development, 2nd edition, or Bayley Scales of Infant and Toddler Development, 3rd edition...
March 5, 2018: Journal of Pediatrics
P Ortiz-Sanchez, F Mulas, L Abad-Mas, P Roca, R Gandia-Beneto
INTRODUCTION: Autism spectrum disorder (ASD) is a neurodevelopmental disorder associated with impairments in executive function, language, emotional function, and social function. Its anatomofunctional substrate is related to a disorganization of the brain's functional connections. The aim is to investigate the cerebral connections in subjects with ASD through the analysis of the interhemispheric coherence (IHC) of the quantified electroencephalogram and its changes after dolphin assisted therapy (DAT) versus therapeutical intervention without dolphins (TIWD)...
March 1, 2018: Revista de Neurologia
Merle Boerrigter, Anneke Vermeulen, Henri Marres, Margreet Langereis
The aim of this study was to compare the personality traits of adolescents with cochlear implants (CIs) to a reference group (normal-hearing peers). In the past, the personality development of hearing impaired adolescents was severely compromised. Improved speech perception with CI significantly increased their perspectives. In addition, differences between the reference group and CI users were investigated on personality traits according to level of speech perception skills (high/low) and level of language comprehension (adequate/poor)...
2018: Frontiers in Psychology
Yan Guo, Mei Yang, Yaqiong Yan, Liang Wang, Jie Gong
This study aimed to explore the sex differentials in correlations between functional fitness (FF) and cognitive impairment (CI) in older adults without dementia. A community-based cross-sectional study was conducted using 2096 adults more than 65 years of age. The Senior Fitness test and Mini-mental State Examination (MMSE) were used to measure FF and cognitive performance. Canonical correlation analysis (CCA) was performed to evaluate the relationships between FF and MMSE. Our results confirmed the relationships between FF and CI, furthermore FF and MMSE were significantly different between men and women (P < 0...
March 7, 2018: Scientific Reports
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