Michitaka Funayama, Yoshitaka Nakagawa, Asuka Nakajima, Taketo Takata, Yu Mimura, Masaru Mimura
BACKGROUND: The timing of progression of logopenic variant primary progressive aphasia (lvPPA) to severe dementia has not been elucidated. To address this shortcoming, 10 patients with lvPPA were continuously followed. METHODS: Patients were assessed with the annual rate of change in the Clinical Dementia Rating (CDR) sum of boxes and period from lvPPA onset to the onset of benchmark signs, including mild, moderate, or severe dementia, episodic memory deficits, topographical disorientation, difficulties with using controls for electronic appliances, and conceptual apraxia...
December 2019: Neurological Sciences