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https://www.readbyqxmd.com/read/28821841/bacterial-foraging-optimization-genetic-algorithm-for-multiple-sequence-alignment-with-multi-objectives
#1
P Manikandan, D Ramyachitra
This research work focus on the multiple sequence alignment, as developing an exact multiple sequence alignment for different protein sequences is a difficult computational task. In this research, a hybrid algorithm named Bacterial Foraging Optimization-Genetic Algorithm (BFO-GA) algorithm is aimed to improve the multi-objectives and carrying out measures of multiple sequence alignment. The proposed algorithm employs multi-objectives such as variable gap penalty minimization, maximization of similarity and non-gap percentage...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28818670/depictive-and-metric-body-size-estimation-in-anorexia-nervosa-and-bulimia-nervosa-a-systematic-review-and-meta-analysis
#2
REVIEW
Simone Claire Mölbert, Lukas Klein, Anne Thaler, Betty J Mohler, Chiara Brozzo, Peter Martus, Hans-Otto Karnath, Stephan Zipfel, Katrin Elisabeth Giel
A distorted representation of one's own body is a diagnostic criterion and core psychopathology of both anorexia nervosa (AN) and bulimia nervosa (BN). Despite recent technical advances in research, it is still unknown whether this body image disturbance is characterized by body dissatisfaction and a low ideal weight and/or includes a distorted perception or processing of body size. In this article, we provide an update and meta-analysis of 42 articles summarizing measures and results for body size estimation (BSE) from 926 individuals with AN, 536 individuals with BN and 1920 controls...
August 10, 2017: Clinical Psychology Review
https://www.readbyqxmd.com/read/28817627/analysing-researchers-outreach-efforts-and-the-association-with-publication-metrics-a-case-study-of-kudos
#3
Mojisola Erdt, Htet Htet Aung, Ashley Sara Aw, Charlie Rapple, Yin-Leng Theng
With the growth of scholarly collaboration networks and social communication platforms, members of the scholarly community are experimenting with their approach to disseminating research outputs, in an effort to increase their audience and outreach. However, from a researcher's point of view, it is difficult to determine whether efforts to make work more visible are worthwhile (in terms of the association with publication metrics) and within that, difficult to assess which platform or network is most effective for sharing work and connecting to a wider audience...
2017: PloS One
https://www.readbyqxmd.com/read/28817569/long-term-assessment-of-whale-shark-population-demography-and-connectivity-using-photo-identification-in-the-western-atlantic-ocean
#4
Jennifer A McKinney, Eric R Hoffmayer, Jason Holmberg, Rachel T Graham, William B Driggers, Rafael de la Parra-Venegas, Beatriz E Galván-Pastoriza, Steve Fox, Simon J Pierce, Alistair D M Dove
The predictable occurrence of whale sharks, Rhincodon typus, has been well documented in several areas. However, information relating to their migratory patterns, residency times and connectivity across broad spatial scales is limited. In the present study photo-identification data is used to describe whale shark population structure and connectivity among known aggregation sites within the Western Central Atlantic Ocean (WCA). From 1999 to 2015, 1,361 individuals were identified from four distinct areas: the Yucatan Peninsula, Mexico (n = 1,115); Honduras (n = 146); northern Gulf of Mexico, United States (n = 112), and Belize (n = 49)...
2017: PloS One
https://www.readbyqxmd.com/read/28817430/beyond-citation-rates-a-real-time-impact-analysis-of-health-professions-education-research-using-altmetrics
#5
Lauren A Maggio, Holly S Meyer, Anthony R Artino
PURPOSE: To complement traditional citation-based metrics, which take years to accrue and indicate only academic attention, academia has begun considering altmetrics or alternative metrics, which provide timely feedback on an article's impact by tracking its dissemination via nontraditional outlets, such as blogs and social media, across audiences. This article describes altmetrics and examines altmetrics attention, outlets used, and top article characteristics for health professions education (HPE) research...
August 16, 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28817322/diverging-life-expectancies-and-voting-patterns-in-the-2016-us-presidential-election
#6
Jacob Bor
OBJECTIVES: To assess whether voting patterns in the 2016 US presidential election were correlated with long-run trends in county life expectancy. METHODS: I examined county-level voting data from the 2008 and 2016 presidential elections and assessed Donald Trump's share of the 2016 vote, change in the Republican vote share between 2008 and 2016, and changes in absolute numbers of Democratic and Republican votes. County-level estimates of life expectancy at birth were obtained for 1980 and 2014 from the Institute for Health Metrics and Evaluation...
August 17, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28815771/molstack-interactive-visualization-tool-for-presentation-interpretation-and-validation-of-macromolecules-and-electron-density-maps
#7
Przemyslaw J Porebski, Piotr Sroka, Heping Zheng, David R Cooper, Wladek Minor
Our understanding of the world of biomolecular structures is based upon the interpretation of macromolecular models, of which ∼ 90% are themselves the interpretation of electron density maps. This structural information guides scientific progress and exploration in many biomedical disciplines. The Protein Data Bank's web portals have made these structures available for mass scientific consumption and greatly broaden the scope of information presented in scientific publications. The portals provide numerous quality metrics; however, the portion of the structure that is most vital for interpretation of the function may have the most difficult to interpret electron density and this ambiguity is not reflected by any single metric...
August 17, 2017: Protein Science: a Publication of the Protein Society
https://www.readbyqxmd.com/read/28815261/author-impact-metrics-in-communication-sciences-and-disorder-research
#8
Andrew Stuart, Sarah P Faucette, William Joseph Thomas
Purpose: The purpose was to examine author-level impact metrics for faculty in the communication sciences and disorder research field across a variety of databases. Method: Author-level impact metrics were collected for faculty from 257 accredited universities in the United States and Canada. Three databases (i.e., Google Scholar, ResearchGate, and Scopus) were utilized. Results: Faculty expertise was in audiology (24.4%; n = 490) and speech-language pathology (75...
August 16, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28814265/a-genome-wide-transcriptome-map-of-pistachio-pistacia-vera-l-provides-novel-insights-into-salinity-related-genes-and-marker-discovery
#9
Maryam Moazzzam Jazi, Seyed Mahdi Seyedi, Esmaeil Ebrahimie, Mansour Ebrahimi, Gianluca De Moro, Christopher Botanga
BACKGROUND: Pistachio (Pistacia vera L.) is one of the most important commercial nut crops worldwide. It is a salt-tolerant and long-lived tree, with the largest cultivation area in Iran. Climate change and subsequent increased soil salt content have adversely affected the pistachio yield in recent years. However, the lack of genomic/global transcriptomic sequences on P. vera impedes comprehensive researches at the molecular level. Hence, whole transcriptome sequencing is required to gain insight into functional genes and pathways in response to salt stress...
August 17, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28812906/recent-advances-in-ct-imaging-in-chronic-obstructive-pulmonary-disease
#10
Sandeep Bodduluri, Joseph M Reinhardt, Eric A Hoffman, John D Newell, Surya P Bhatt
Lung imaging is increasingly being used to diagnose, quantify and phenotype chronic obstructive pulmonary disease (COPD). Although spirometry is the gold standard for the diagnosis of COPD and for severity staging, the role of computed tomography (CT) imaging has expanded in both clinical practice and research. COPD is a heterogeneous disease with considerable variability in clinical features, radiographic disease, progression and outcomes. Recent studies have examined the utility of CT imaging in enhancing diagnostic certainty, improving phenotyping, predicting disease progression and prognostication, patient selection for intervention, and also in furthering our understanding of the complex pathophysiology of this disease...
August 16, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28809686/salient-region-detection-using-diffusion-process-on-a-2-layer-sparse-graph
#11
Li Zhou, Zhaohui Yang, Zongtan Zhou, Dewen Hu
Diffusion-based salient region detection has recently received intense research attention. In this paper, we present some effective improvements concerning two important aspects of diffusion-based methods: the construction of the diffusion matrix and the seed vector. First, we construct a 2-layer sparse graph, which is generated by connecting each node to its neighboring nodes and the most similar node that shares common boundaries with its neighboring nodes. Compared with the most frequently used 2-layer neighborhood graph, our graph not only effectively uses local spatial relationships, but also removes dissimilar redundant nodes...
August 11, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28807753/a-critical-evaluation-of-validity-and-utility-of-translational-imaging-in-pain-and-analgesia-utilizing-functional-imaging-to-enhance-the-process
#12
REVIEW
Jaymin Upadhyay, Christian Geber, Richard Hargreaves, Frank Birklein, David Borsook
Assessing clinical pain and metrics related to function or quality of life predominantly relies on patient reported subjective measures. These outcome measures are generally not applicable to the preclinical setting where early signs pointing to analgesic value of a therapy are sought, thus introducing difficulties in animal to human translation in pain research. Evaluating brain function in patients and respective animal model(s) has the potential to characterize mechanisms associated with pain or pain-related phenotypes and thereby provide a means of laboratory to clinic translation...
August 11, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28807638/food-waste-in-the-national-school-lunch-program-1978-2015-a-systematic-review
#13
Carmen Byker Shanks, Jinan Banna, Elena L Serrano
BACKGROUND: Food waste studies have been used for more than 40 years to assess nutrient intake, dietary quality, menu performance, food acceptability, cost, and effectiveness of nutrition education in the National School Lunch Program (NSLP). OBJECTIVE: Describe methods used to measure food waste and respective results in the NSLP across time. METHODS: A systematic review using PubMed, Science Direct, Informaworld, and Institute of Scientific Information Web of Knowledge was conducted using the following search terms: waste, school lunch, plate waste, food waste, kitchen, half method, quarter method, weight, and photography...
August 11, 2017: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/28803527/science-s-disparate-responsibilities-patterns-across-european-countries
#14
Niels Mejlgaard
It is a distinctive feature of European science policy that science is expected to meet economic and broader societal objectives simultaneously. Science should be governed democratically and take significant responsibilities towards the economy, the political system and civil society, but the coherency of these multiple claims is underexplored. Using metrics that emerge from both quantitative and qualitative studies, we examine the interrelatedness of different responsibilities at the level of countries. A total of 33 European Union member states and associated countries are included in the analysis...
August 1, 2017: Public Understanding of Science
https://www.readbyqxmd.com/read/28802742/the-challenges-of-measuring-in-vivo-knee-collateral-ligament-strains-using-ultrasound
#15
Laura C Slane, Josh A Slane, Jan D'hooge, Lennart Scheys
Ultrasound-based methods have shown promise in their ability to characterize non-uniform deformations in large energy-storing tendons such as the Achilles and patellar tendons, yet applications to other areas of the body have been largely unexplored. The noninvasive quantification of collateral ligament strain could provide an important clinical metric of knee frontal plane stability, which is relevant in ligament injury and for measuring outcomes following total knee arthroplasty. In this pilot cadaveric experiment, we investigated the possibility of measuring collateral ligament strain with our previously validated speckle-tracking approach, but encountered a number of challenges during both data acquisition and processing...
July 31, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28801207/crediblemeds-org-what-does-it-offer
#16
REVIEW
Raymond L Woosley, Kristin Black, C William Heise, Klaus Romero
Since the 1990s, when numerous non-cardiac drugs were first recognized to have the potential to prolong the QT interval and cause torsades de pointes (TdP), clinicians, drug regulators, drug developers, and clinical investigators have become aware of the complexities of assessing evidence and determining TdP causality for the many drugs being marketed or under development. To facilitate better understanding, the Arizona Center for Education and Research on Therapeutics, known as AZCERT, has developed the CredibleMeds...
August 1, 2017: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28800717/multidimensional-inventory-of-hypochondriacal-traits-an-examination-of-a-bifactor-model-and-measurement-invariance-between-those-with-and-without-a-self-reported-medical-condition
#17
Joseph R Bardeen, Thomas A Fergus
The Multidimensional Inventory of Hypochondriacal Traits (MIHT) is a self-report measure that assesses four interrelated domains of health anxiety (i.e., Cognitive, Behavioral, Perceptual, Affective). Prior research has supported a correlated four-factor model, as well as a hierarchical model, in which each of the four factors load onto the higher order health anxiety construct. However, a bifactor modeling approach has yet to be used to examine the factor structure of the MIHT. Results supported a bifactor model of the MIHT in three different samples (i...
August 1, 2017: Assessment
https://www.readbyqxmd.com/read/28800135/network-analysis-of-gut-microbiota-literature-an-overview-of-the-research-landscape-in-non-human-animal-studies
#18
Emily L Pascoe, Heidi C Hauffe, Julian R Marchesi, Sarah E Perkins
A wealth of human studies have demonstrated the importance of gut microbiota to health. Research on non-human animal gut microbiota is now increasing, but what insight does it provide? We reviewed 650 publications from this burgeoning field (2009-2016) and determined that animals driving this research were predominantly 'domestic' (48.2%), followed by 'model' (37.5%), with least studies on 'wild' (14.3%) animals. Domestic studies largely experimentally perturbed microbiota (81.8%) and studied mammals (47.9%), often to improve animal productivity...
August 11, 2017: ISME Journal
https://www.readbyqxmd.com/read/28800111/translational-imaging-spectroscopy-for-proximal-sensing
#19
Christian Rogass, Friederike M Koerting, Christian Mielke, Maximilian Brell, Nina K Boesche, Maria Bade, Christian Hohmann
Proximal sensing as the near field counterpart of remote sensing offers a broad variety of applications. Imaging spectroscopy in general and translational laboratory imaging spectroscopy in particular can be utilized for a variety of different research topics. Geoscientific applications require a precise pre-processing of hyperspectral data cubes to retrieve at-surface reflectance in order to conduct spectral feature-based comparison of unknown sample spectra to known library spectra. A new pre-processing chain called GeoMAP-Trans for at-surface reflectance retrieval is proposed here as an analogue to other algorithms published by the team of authors...
August 11, 2017: Sensors
https://www.readbyqxmd.com/read/28798821/benchmarking-quality-for-renal-cancer-surgery-canadian-kidney-cancer-information-system-ckcis-perspective
#20
Keith A Lawson, Olli Saarela, Zhihui Liu, Luke T Lavallée, Rodney H Breau, Lori Wood, Michael A S Jewett, Anil Kapoor, Simon Tanguay, Ronald B Moore, Ricardo Rendon, Frederic Pouliot, Peter C Black, Jun Kawakami, Darrel Drachenberg, Antonio Finelli
INTRODUCTION: There is a lack of validated quality metrics to evaluate the care of patients receiving surgery for renal cell carcinoma (RCC). To address this, the Kidney Cancer Research Network of Canada defined a list of quality indicators (QI) to assess hospital-level performance. We have case-mix adjusted these QIs to benchmark RCC surgical care at Canadian academic centres. METHODS: The Canadian Kidney Cancer information system (CKCis) was used to measure six QIs: laparoscopic approach proportion (LA), partial nephrectomy proportion (PN), partial nephrectomy in patients with chronic kidney disease (CKDPN), positive margin rate (PMR), partial nephrectomy complication rate (PNCx), and warm ischemia time (WIT)...
August 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
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