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https://www.readbyqxmd.com/read/28338492/the-evolution-of-current-research-impact-metrics-from-bibliometrics-to-altmetrics
#1
Joseph S Butler, I David Kaye, Arjun S Sebastian, Scott C Wagner, Patrick B Morrissey, Gregory D Schroeder, Christopher K Kepler, Alexander R Vaccaro
The prestige of publication has been based on traditional citation metrics, most commonly journal impact factor. However, the Internet has radically changed the speed, flow, and sharing of medical information. Furthermore, the explosion of social media, along with development of popular professional and scientific websites and blogs, has led to the need for alternative metrics, known as altmetrics, to quantify the wider impact of research. We explore the evolution of current research impact metrics and examine the evolving role of altmetrics in measuring the wider impact of research...
March 23, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28338355/the-potential-for-a-targeted-strength-training-programme-to-decrease-asymmetry-and-increase-performance-a-proof-of-concept-in-sprinting
#2
Scott R Brown, Erin R Feldman, Matt R Cross, Eric R Helms, Bruno Marrier, Pierre Samozino, Jean-Benoît Morin
The global application of horizontal force (FH) via hip extension is related to improvements in sprint performance (e.g. maximal velocity [vmax] and power [Pmax]). Little is known regarding the contribution of individual-leg FH and how a difference between the legs (asymmetry) might subsequently affect sprint performance. We assessed a single male athlete for pre-post outcomes of a targeted hip extension training programme on FH asymmetry and sprint performance metrics. An instrumented non-motorised treadmill was used to obtain individual-leg and global sprint kinetics and determine the athlete's strong and weak leg, with regards to the ability to produce FH while sprinting...
March 24, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28337734/diffusion-tensor-imaging-dti-findings-in-adult-civilian-military-and-sport-related-mild-traumatic-brain-injury-mtbi-a-systematic-critical-review
#3
Breton Michael Asken, Steven T DeKosky, James R Clugston, Michael S Jaffee, Russell M Bauer
This review seeks to summarize diffusion tensor imaging (DTI) studies that have evaluated structural changes attributed to the mechanisms of mild traumatic brain injury (mTBI) in adult civilian, military, and athlete populations. Articles from 2002 to 2016 were retrieved from PubMed/MEDLINE, EBSCOhost, and Google Scholar, using a Boolean search string containing the following terms: "diffusion tensor imaging", "diffusion imaging", "DTI", "white matter", "concussion", "mild traumatic brain injury", "mTBI", "traumatic brain injury", and "TBI"...
March 24, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/28337071/international-standards-for-genomes-transcriptomes-and-metagenomes
#4
Christopher E Mason, Ebrahim Afshinnekoo, Scott Tighe, Shixiu Wu, Shawn Levy
Challenges and biases in preparing, characterizing, and sequencing DNA and RNA can have significant impacts on research in genomics across all kingdoms of life, including experiments in single-cells, RNA profiling, and metagenomics (across multiple genomes). Technical artifacts and contamination can arise at each point of sample manipulation, extraction, sequencing, and analysis. Thus, the measurement and benchmarking of these potential sources of error are of paramount importance as next-generation sequencing (NGS) projects become more global and ubiquitous...
March 17, 2017: Journal of Biomolecular Techniques: JBT
https://www.readbyqxmd.com/read/28336790/prioritizing-functional-capacity-as-a-principal-end-point-for-therapies-oriented-to-older-adults-with-cardiovascular-disease-a-scientific-statement-for-healthcare-professionals-from-the-american-heart-association
#5
REVIEW
Daniel E Forman, Ross Arena, Rebecca Boxer, Mary A Dolansky, Janice J Eng, Jerome L Fleg, Mark Haykowsky, Arshad Jahangir, Leonard A Kaminsky, Dalane W Kitzman, Eldrin F Lewis, Jonathan Myers, Gordon R Reeves, Win-Kuang Shen
Adults are living longer, and cardiovascular disease is endemic in the growing population of older adults who are surviving into old age. Functional capacity is a key metric in this population, both for the perspective it provides on aggregate health and as a vital goal of care. Whereas cardiorespiratory function has long been applied by cardiologists as a measure of function that depended primarily on cardiac physiology, multiple other factors also contribute, usually with increasing bearing as age advances...
March 23, 2017: Circulation
https://www.readbyqxmd.com/read/28334136/a-review-of-network-based-approaches-to-drug-repositioning
#6
Maryam Lotfi Shahreza, Nasser Ghadiri, Sayed Rasoul Mousavi, Jaleh Varshosaz, James R Green
Experimental drug development is time-consuming, expensive and limited to a relatively small number of targets. However, recent studies show that repositioning of existing drugs can function more efficiently than de novo experimental drug development to minimize costs and risks. Previous studies have proven that network analysis is a versatile platform for this purpose, as the biological networks are used to model interactions between many different biological concepts. The present study is an attempt to review network-based methods in predicting drug targets for drug repositioning...
February 27, 2017: Briefings in Bioinformatics
https://www.readbyqxmd.com/read/28332310/arboreal-locomotion-in-eurasian-harvest-mice-micromys-minutus-rodentia-muridae-the-gaits-of-small-mammals
#7
Nikolaos-Evangelos Karantanis, Leszek Rychlik, Anthony Herrel, Dionisios Youlatos
Body size imposes significant constraints on arboreal locomotion. Despite the wealth of research in larger arboreal mammals, there is a lack of data on arboreal gaits of small mammals. In this context, the present study explores arboreal locomotion in one of the smallest rodents, the Eurasian harvest mice Micromys minutus (∼10 g). We examined gait metrics (i.e., diagonality, duty factor [DF], DF index, velocity, stride length, and stride frequency) of six adult male mice on simulated arboreal substrates of different sizes (2, 5, 10, and 25 mm) and inclinations (0(0) and 45(0) )...
March 23, 2017: Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology
https://www.readbyqxmd.com/read/28331951/failure-to-rescue-the-elderly-a-superior-quality-metric-for-trauma-centers
#8
G Barmparas, E J Ley, M J Martin, A Ko, M Harada, D Weigmann, K R Catchpole, B L Gewertz
BACKGROUND: Trauma centers require reliable metrics to better compare the quality of care delivered. We compared mortality after a reported complication, termed failure to rescue (FTR), and FTR in the elderly (age >65 years) (FTRE) to determine which is a superior metric to assess quality of care delivered by trauma centers. METHODS: This was a retrospective review of the National Trauma Databank (NTDB) research data sets 2010 and 2011. Patients ≥16 years admitted to centers reporting ≥80% of AIS and/or ≥ 20% of comorbidities with > 200 subjects in the NTDB were selected...
March 22, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/28330832/virtual-versus-in-person-focus-groups-comparison-of-costs-recruitment-and-participant-logistics
#9
Douglas J Rupert, Jon A Poehlman, Jennifer J Hayes, Sarah E Ray, Rebecca R Moultrie
BACKGROUND: Virtual focus groups-such as online chat and video groups-are increasingly promoted as qualitative research tools. Theoretically, virtual groups offer several advantages, including lower cost, faster recruitment, greater geographic diversity, enrollment of hard-to-reach populations, and reduced participant burden. However, no study has compared virtual and in-person focus groups on these metrics. OBJECTIVE: To rigorously compare virtual and in-person focus groups on cost, recruitment, and participant logistics...
March 22, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28328983/novel-keyword-co-occurrence-network-based-methods-to-foster-systematic-reviews-of-scientific-literature
#10
Srinivasan Radhakrishnan, Serkan Erbis, Jacqueline A Isaacs, Sagar Kamarthi
Systematic reviews of scientific literature are important for mapping the existing state of research and highlighting further growth channels in a field of study, but systematic reviews are inherently tedious, time consuming, and manual in nature. In recent years, keyword co-occurrence networks (KCNs) are exploited for knowledge mapping. In a KCN, each keyword is represented as a node and each co-occurrence of a pair of words is represented as a link. The number of times that a pair of words co-occurs in multiple articles constitutes the weight of the link connecting the pair...
2017: PloS One
https://www.readbyqxmd.com/read/28324322/measurement-invariance-of-the-satisfaction-with-life-scale-reviewing-three-decades-of-research
#11
REVIEW
Scott D Emerson, Martin Guhn, Anne M Gadermann
PURPOSE: The Satisfaction with Life Scale (SWLS) is a widely used measure of life satisfaction, a key aspect in quality of life. The SWLS has been used across many socio-demographic groups. Comparison of life satisfaction across different subgroups (e.g., cultures) is meaningful to researchers; such cross-group comparison presupposes that validity of the inferences from SWLS scores holds across various subgroups (measurement invariance: MI). The aim of the present review was to identify, summarize, and evaluate research testing measurement invariance of the SWLS...
March 21, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28323435/quantifying-selection-pressure
#12
Evert Haasdijk, Jacqueline Heinerman
Selection is an essential component of any evolutionary systemand analysing this fundamental force in evolution can provide relevant insights into the evolutionary development of a population. The 1990s and early 2000s saw a substantial number of publications that investigated selection pressure through methods such as takeover time and Markov chain analysis. Over the last decade, however, interest in the analysis of selection in evolutionary computing has waned. The established methods for analysis of selection pressure provide little insight when selection is based in more than comparison of fitness values...
March 21, 2017: Evolutionary Computation
https://www.readbyqxmd.com/read/28320690/use-of-getcheckedonline-a-comprehensive-web-based-testing-service-for-sexually-transmitted-and-blood-borne-infections
#13
Mark Gilbert, Travis Salway, Devon Haag, Christopher K Fairley, Jason Wong, Troy Grennan, Zhaida Uddin, Christopher S Buchner, Tom Wong, Mel Krajden, Mark Tyndall, Jean Shoveller, Gina Ogilvie
BACKGROUND: The British Columbia Centre for Disease Control implemented a comprehensive Web-based testing service GetCheckedOnline (GCO) in September 2014 in Vancouver, Canada. GCO's objectives are to increase testing for sexually transmitted and blood-borne infections (STBBIs), reach high-prevalence populations facing testing barriers, and increase clinical STI service capacity. GCO was promoted through email invitations to provincial STI clinic clients, access codes to clients unable to access immediate clinic-based testing (deferred testers), and a campaign to gay, bisexual, and other men who have sex with men (MSM)...
March 20, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28319741/influence-of-sampling-approach-on-concentrations-of-legacy-and-novel-brominated-flame-retardants-in-indoor-dust
#14
Layla Salih Al-Omran, Stuart Harrad
The study investigates the impact of sampling method on the concentrations of PBDEs (BDE-28, BDE-47, BDE-99, BDE-100, BDE-153, BDE-154, BDE-183, and BDE-209) and NBFRs (PBEB, EH-TBB, BEH-TEBP, BTBPE and DBDPE) in indoor dust. A total of 36 dust samples were collected from 12 homes in Birmingham, UK (3 samples per home comprising researcher collected dust - both RCD from the living room (RCDL) and bedroom (RCDB), with an additional householder vacuum dust sample - HHVD). BDE-209 was the predominant compound, with average concentrations of 2642, 2336 and 2634 ng/g in RCDL, RCDB and HHVD respectively...
February 22, 2017: Chemosphere
https://www.readbyqxmd.com/read/28319469/understanding-traditional-research-impact-metrics
#15
Joseph S Butler, Arjun S Sebastian, I David Kaye, Scott C Wagner, Patrick B Morrissey, Gregory D Schroeder, Christopher K Kepler, Alexander R Vaccaro
Traditionally, the success of a researcher has been judged by the number of publications he or she has published in peer-review, indexed, high impact journals. However, to quantify the impact of research in the wider scientific community, a number of traditional metrics have been used, including Impact Factor, SCImago Journal Rank, Eigenfactor Score, and Article Influence Score. This article attempts to provide a broad overview of the main traditional impact metrics that have been used to assess scholarly output and research impact...
March 17, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28317104/contact-and-contagion-bighorn-sheep-demographic-states-vary-in-probability-of-transmission-given-contact
#16
Kezia R Manlove, E Frances Cassirer, Raina K Plowright, Paul C Cross, Peter J Hudson
1.Understanding both contact and probability of transmission given contact are key to managing wildlife disease. However, wildlife disease research tends to focus on contact heterogeneity, in part because probability of transmission given contact is notoriously difficult to measure. Here we present a first step toward empirically investigating probability of transmission given contact in free-ranging wildlife. 2.We used measured contact networks to test whether bighorn sheep demographic states vary systematically in infectiousness or susceptibility to Mycoplasma ovipneumoniae, an agent responsible for bighorn sheep pneumonia...
March 20, 2017: Journal of Animal Ecology
https://www.readbyqxmd.com/read/28314841/academic-cancer-center-phase-i-program-development
#17
Arthur E Frankel, Keith T Flaherty, George J Weiner, Robert Chen, Nilofer S Azad, Michael J Pishvaian, John A Thompson, Matthew H Taylor, Daruka Mahadevan, A Craig Lockhart, Ulka N Vaishampayan, Jordan D Berlin, David C Smith, John Sarantopoulos, Matthew Riese, Mansoor N Saleh, Chul Ahn, Eugene P Frenkel
Multiple factors critical to the effectiveness of academic phase I cancer programs were assessed among 16 academic centers in the U.S. Successful cancer centers were defined as having broad phase I and I/II clinical trial portfolios, multiple investigator-initiated studies, and correlative science. The most significant elements were institutional philanthropic support, experienced clinical research managers, robust institutional basic research, institutional administrative efforts to reduce bureaucratic regulatory delays, phase I navigators to inform patients and physicians of new studies, and a large cancer center patient base...
March 17, 2017: Oncologist
https://www.readbyqxmd.com/read/28304360/traffic-related-air-pollution-and-childhood-asthma-recent-advances-and-remaining-gaps-in-the-exposure-assessment-methods
#18
REVIEW
Haneen Khreis, Mark J Nieuwenhuijsen
Background: Current levels of traffic-related air pollution (TRAP) are associated with the development of childhood asthma, although some inconsistencies and heterogeneity remain. An important part of the uncertainty in studies of TRAP-associated asthma originates from uncertainties in the TRAP exposure assessment and assignment methods. In this work, we aim to systematically review the exposure assessment methods used in the epidemiology of TRAP and childhood asthma, highlight recent advances, remaining research gaps and make suggestions for further research...
March 17, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28303327/rotational-error-in-path-integration-encoding-and-execution-errors-in-angle-reproduction
#19
Elizabeth R Chrastil, William H Warren
Path integration is fundamental to human navigation. When a navigator leaves home on a complex outbound path, they are able to keep track of their approximate position and orientation and return to their starting location on a direct homebound path. However, there are several sources of error during path integration. Previous research has focused almost exclusively on encoding error-the error in registering the outbound path in memory. Here, we also consider execution error-the error in the response, such as turning and walking a homebound trajectory...
March 16, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28303099/meet-spinky-an-open-source-spindle-and-k-complex-detection-toolbox-validated-on-the-open-access-montreal-archive-of-sleep-studies-mass
#20
Tarek Lajnef, Christian O'Reilly, Etienne Combrisson, Sahbi Chaibi, Jean-Baptiste Eichenlaub, Perrine M Ruby, Pierre-Emmanuel Aguera, Mounir Samet, Abdennaceur Kachouri, Sonia Frenette, Julie Carrier, Karim Jerbi
Sleep spindles and K-complexes are among the most prominent micro-events observed in electroencephalographic (EEG) recordings during sleep. These EEG microstructures are thought to be hallmarks of sleep-related cognitive processes. Although tedious and time-consuming, their identification and quantification is important for sleep studies in both healthy subjects and patients with sleep disorders. Therefore, procedures for automatic detection of spindles and K-complexes could provide valuable assistance to researchers and clinicians in the field...
2017: Frontiers in Neuroinformatics
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