Shubham Singh, Sangeeta Saxena, Himani Sharma, Keshav Raj Paudel, Amlan Chakraborty, Ronan MacLoughlin, Brian G Oliver, Gaurav Gupta, Poonam Negi, Sachin Kumar Singh, Kamal Dua
Lung cancer (LC) is the second leading cause of death across the globe after breast cancer. There are two types of LC viz. small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). NSCLC accounts for approximately 85% of all LC cases. NSCLC affects smokers and people who do not smoke and mainly arises in bronchi and peripheral lungs tissue. LC is often characterized by the alterations of key genes such as EGFR, Wnt/β-catenin signaling, ALK, MET, K-Ras and p53 and downstream signaling pathways associated with tumor growth, differentiation, and survival...
February 23, 2024: Pathology, Research and Practice