keyword
https://read.qxmd.com/read/38467878/author-correction-the-type-ii-raf-inhibitor-tovorafenib-in-relapsed-refractory-pediatric-low-grade-glioma-the-phase-2-firefly-1-trial
#1
Lindsay B Kilburn, Dong-Anh Khuong-Quang, Jordan R Hansford, Daniel Landi, Jasper van der Lugt, Sarah E S Leary, Pablo Hernáiz Driever, Simon Bailey, Sébastien Perreault, Geoffrey McCowage, Angela J Waanders, David S Ziegler, Olaf Witt, Patricia A Baxter, Hyoung Jin Kang, Timothy E Hassall, Jung Woo Han, Darren Hargrave, Andrea T Franson, Michal Yalon Oren, Helen Toledano, Valérie Larouche, Cassie Kline, Mohamed S Abdelbaki, Nada Jabado, Nicholas G Gottardo, Nicolas U Gerber, Nicholas S Whipple, Devorah Segal, Susan N Chi, Liat Oren, Enrica E K Tan, Sabine Mueller, Izzy Cornelio, Lisa McLeod, Xin Zhao, Ashley Walter, Daniel Da Costa, Peter Manley, Samuel C Blackman, Roger J Packer, Karsten Nysom
No abstract text is available yet for this article.
March 11, 2024: Nature Medicine
https://read.qxmd.com/read/37978284/the-type-ii-raf-inhibitor-tovorafenib-in-relapsed-refractory-pediatric-low-grade-glioma-the-phase-2-firefly-1-trial
#2
JOURNAL ARTICLE
Lindsay B Kilburn, Dong-Anh Khuong-Quang, Jordan R Hansford, Daniel Landi, Jasper van der Lugt, Sarah E S Leary, Pablo Hernáiz Driever, Simon Bailey, Sébastien Perreault, Geoffrey McCowage, Angela J Waanders, David S Ziegler, Olaf Witt, Patricia A Baxter, Hyoung Jin Kang, Timothy E Hassall, Jung Woo Han, Darren Hargrave, Andrea T Franson, Michal Yalon Oren, Helen Toledano, Valérie Larouche, Cassie Kline, Mohamed S Abdelbaki, Nada Jabado, Nicholas G Gottardo, Nicolas U Gerber, Nicholas S Whipple, Devorah Segal, Susan N Chi, Liat Oren, Enrica E K Tan, Sabine Mueller, Izzy Cornelio, Lisa McLeod, Xin Zhao, Ashley Walter, Daniel Da Costa, Peter Manley, Samuel C Blackman, Roger J Packer, Karsten Nysom
BRAF genomic alterations are the most common oncogenic drivers in pediatric low-grade glioma (pLGG). Arm 1 (n = 77) of the ongoing phase 2 FIREFLY-1 (PNOC026) trial investigated the efficacy of the oral, selective, central nervous system-penetrant, type II RAF inhibitor tovorafenib (420 mg m- 2 once weekly; 600 mg maximum) in patients with BRAF-altered, relapsed/refractory pLGG. Arm 2 (n = 60) is an extension cohort, which provided treatment access for patients with RAF-altered pLGG after arm 1 closure...
November 17, 2023: Nature Medicine
https://read.qxmd.com/read/37851859/optimizing-brain-health-of-united-states-special-operations-forces
#3
JOURNAL ARTICLE
Brian L Edlow, Natalie Gilmore, Samantha L Tromly, Katryna B Deary, Isabella R McKinney, Collin G Hu, Jessica N Kelemen, Chiara Maffei, Chieh-En J Tseng, Gabriel Ramos Llorden, Brian C Healy, Maryam Masood, Ryan J Cali, Timothy Baxter, Eveline F Yao, Heather G Belanger, Dan Benjamini, Peter J Basser, David S Priemer, W Taylor Kimberly, Jonathan R Polimeni, Bruce R Rosen, Bruce Fischl, Nicole R Zurcher, Douglas N Greve, Jacob M Hooker, Susie Y Huang, Adam Caruso, Gregory A Smith, Timothy G Szymanski, Daniel P Perl, Kristen Dams-O'Connor, Christine L Mac Donald, Yelena G Bodien
United States Special Operations Forces (SOF) personnel are frequently exposed to explosive blasts in training and combat. However, the effects of repeated blast exposure on the human brain are incompletely understood. Moreover, there is currently no diagnostic test to detect repeated blast brain injury (rBBI). In this "Human Performance Optimization" article, we discuss how the development and implementation of a reliable diagnostic test for rBBI has the potential to promote SOF brain health, combat readiness, and quality of life...
October 18, 2023: Journal of Special Operations Medicine: a Peer Reviewed Journal for SOF Medical Professionals
https://read.qxmd.com/read/37848036/serotonin-reduction-in-post-acute-sequelae-of-viral-infection
#4
JOURNAL ARTICLE
Andrea C Wong, Ashwarya S Devason, Iboro C Umana, Timothy O Cox, Lenka Dohnalová, Lev Litichevskiy, Jonathan Perla, Patrick Lundgren, Zienab Etwebi, Luke T Izzo, Jihee Kim, Monika Tetlak, Hélène C Descamps, Simone L Park, Stephen Wisser, Aaron D McKnight, Ryan D Pardy, Junwon Kim, Niklas Blank, Shaan Patel, Katharina Thum, Sydney Mason, Jean-Christophe Beltra, Michaël F Michieletto, Shin Foong Ngiow, Brittany M Miller, Megan J Liou, Bhoomi Madhu, Oxana Dmitrieva-Posocco, Alex S Huber, Peter Hewins, Christopher Petucci, Candice P Chu, Gwen Baraniecki-Zwil, Leila B Giron, Amy E Baxter, Allison R Greenplate, Charlotte Kearns, Kathleen Montone, Leslie A Litzky, Michael Feldman, Jorge Henao-Mejia, Boris Striepen, Holly Ramage, Kellie A Jurado, Kathryn E Wellen, Una O'Doherty, Mohamed Abdel-Mohsen, Alan L Landay, Ali Keshavarzian, Timothy J Henrich, Steven G Deeks, Michael J Peluso, Nuala J Meyer, E John Wherry, Benjamin A Abramoff, Sara Cherry, Christoph A Thaiss, Maayan Levy
Post-acute sequelae of COVID-19 (PASC, "Long COVID") pose a significant global health challenge. The pathophysiology is unknown, and no effective treatments have been found to date. Several hypotheses have been formulated to explain the etiology of PASC, including viral persistence, chronic inflammation, hypercoagulability, and autonomic dysfunction. Here, we propose a mechanism that links all four hypotheses in a single pathway and provides actionable insights for therapeutic interventions. We find that PASC are associated with serotonin reduction...
October 9, 2023: Cell
https://read.qxmd.com/read/37770427/integrated-molecular-and-multiparametric-mri-mapping-of-high-grade-glioma-identifies-regional-biologic-signatures
#5
JOURNAL ARTICLE
Leland S Hu, Fulvio D'Angelo, Taylor M Weiskittel, Francesca P Caruso, Shannon P Fortin Ensign, Mylan R Blomquist, Matthew J Flick, Lujia Wang, Christopher P Sereduk, Kevin Meng-Lin, Gustavo De Leon, Ashley Nespodzany, Javier C Urcuyo, Ashlyn C Gonzales, Lee Curtin, Erika M Lewis, Kyle W Singleton, Timothy Dondlinger, Aliya Anil, Natenael B Semmineh, Teresa Noviello, Reyna A Patel, Panwen Wang, Junwen Wang, Jennifer M Eschbacher, Andrea Hawkins-Daarud, Pamela R Jackson, Itamar S Grunfeld, Christian Elrod, Gina L Mazza, Sam C McGee, Lisa Paulson, Kamala Clark-Swanson, Yvette Lassiter-Morris, Kris A Smith, Peter Nakaji, Bernard R Bendok, Richard S Zimmerman, Chandan Krishna, Devi P Patra, Naresh P Patel, Mark Lyons, Matthew Neal, Kliment Donev, Maciej M Mrugala, Alyx B Porter, Scott C Beeman, Todd R Jensen, Kathleen M Schmainda, Yuxiang Zhou, Leslie C Baxter, Christopher L Plaisier, Jing Li, Hu Li, Anna Lasorella, C Chad Quarles, Kristin R Swanson, Michele Ceccarelli, Antonio Iavarone, Nhan L Tran
Sampling restrictions have hindered the comprehensive study of invasive non-enhancing (NE) high-grade glioma (HGG) cell populations driving tumor progression. Here, we present an integrated multi-omic analysis of spatially matched molecular and multi-parametric magnetic resonance imaging (MRI) profiling across 313 multi-regional tumor biopsies, including 111 from the NE, across 68 HGG patients. Whole exome and RNA sequencing uncover unique genomic alterations to unresectable invasive NE tumor, including subclonal events, which inform genomic models predictive of geographic evolution...
September 28, 2023: Nature Communications
https://read.qxmd.com/read/37735592/prior-vaccination-promotes-early-activation-of-memory-t-cells-and-enhances-immune-responses-during-sars-cov-2-breakthrough-infection
#6
JOURNAL ARTICLE
Mark M Painter, Timothy S Johnston, Kendall A Lundgreen, Jefferson J S Santos, Juliana S Qin, Rishi R Goel, Sokratis A Apostolidis, Divij Mathew, Bria Fulmer, Justine C Williams, Michelle L McKeague, Ajinkya Pattekar, Ahmad Goode, Sean Nasta, Amy E Baxter, Josephine R Giles, Ashwin N Skelly, Laura E Felley, Maura McLaughlin, Joellen Weaver, Oliva Kuthuru, Jeanette Dougherty, Sharon Adamski, Sherea Long, Macy Kee, Cynthia Clendenin, Ricardo da Silva Antunes, Alba Grifoni, Daniela Weiskopf, Alessandro Sette, Alexander C Huang, Daniel J Rader, Scott E Hensley, Paul Bates, Allison R Greenplate, E John Wherry
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of vaccinated individuals is increasingly common but rarely results in severe disease, likely due to the enhanced potency and accelerated kinetics of memory immune responses. However, there have been few opportunities to rigorously study early recall responses during human viral infection. To better understand human immune memory and identify potential mediators of lasting vaccine efficacy, we used high-dimensional flow cytometry and SARS-CoV-2 antigen probes to examine immune responses in longitudinal samples from vaccinated individuals infected during the Omicron wave...
October 2023: Nature Immunology
https://read.qxmd.com/read/37408850/effect-of-two-years-of-doxycycline-treatment-on-infrarenal-aortic-neck-diameter
#7
JOURNAL ARTICLE
Annalise M Panthofer, Sydney L Olson, Brooks L Rademacher, Larry W Kraiss, William C Blackwelder, B Timothy Baxter, Jason N MacTaggart, Barry T Katzen, Scott S Berman, Jon S Matsumura
OBJECTIVE: Endovascular aneurysm repair (EVAR) is a widely used option for patients with suitable vascular anatomy who have a large infrarenal abdominal aortic aneurysm (AAA). Neck diameter is the primary anatomical determinant of EVAR eligibility and device durability. Doxycycline has been proposed to stabilise the proximal neck after EVAR. This study explored doxycycline mediated aortic neck stabilisation in patients with small AAA, monitored by computed tomography over two years. METHODS: This was a multicentre prospective randomised clinical trial...
2023: EJVES vascular forum
https://read.qxmd.com/read/36798171/prior-vaccination-enhances-immune-responses-during-sars-cov-2-breakthrough-infection-with-early-activation-of-memory-t-cells-followed-by-production-of-potent-neutralizing-antibodies
#8
Mark M Painter, Timothy S Johnston, Kendall A Lundgreen, Jefferson J S Santos, Juliana S Qin, Rishi R Goel, Sokratis A Apostolidis, Divij Mathew, Bria Fulmer, Justine C Williams, Michelle L McKeague, Ajinkya Pattekar, Ahmad Goode, Sean Nasta, Amy E Baxter, Josephine R Giles, Ashwin N Skelly, Laura E Felley, Maura McLaughlin, Joellen Weaver, Oliva Kuthuru, Jeanette Dougherty, Sharon Adamski, Sherea Long, Macy Kee, Cynthia Clendenin, Ricardo da Silva Antunes, Alba Grifoni, Daniela Weiskopf, Alessandro Sette, Alexander C Huang, Daniel J Rader, Scott E Hensley, Paul Bates, Allison R Greenplate, E John Wherry
SARS-CoV-2 infection of vaccinated individuals is increasingly common but rarely results in severe disease, likely due to the enhanced potency and accelerated kinetics of memory immune responses. However, there have been few opportunities to rigorously study early recall responses during human viral infection. To better understand human immune memory and identify potential mediators of lasting vaccine efficacy, we used high-dimensional flow cytometry and SARS-CoV-2 antigen probes to examine immune responses in longitudinal samples from vaccinated individuals infected during the Omicron wave...
February 6, 2023: bioRxiv
https://read.qxmd.com/read/36450401/2022-canadian-surgery-forum-sept-15-17-2022-abstracts-presented-at-the-2022-canadian-surgery-forum-in-toronto-ontario
#9
JOURNAL ARTICLE
Yasser Selim, Élise Di Lena, Nadia Safa, Sid Rahman, Pepa Kaneva, Liane Feldman, Nawaf Abu-Omar, Zarrukh Baig, Nathan Ginther, Dilip Gill, Zarrukh Baig, Zaini Sarwar, Carlos Verdiales, Mike Moser, Kevin Verhoeff, Valentin Mocanu, Breanna Fang, Jerry Dang, Warren Sun, Noah Switzer, Daniel Birch, Shahzeer Karmali, Julie La, Anood Alqaydi, Xuejiao Wei, Genevieve Digby, Susan Brogly, Shaila Merchant, Kieran Purich, Kevin Verhoeff, Alexander Miles, Janice Y Kung, A M James Shapiro, David L Bigam, Samantha Albacete, Ashlee Matkin, Danielle Dumestre, Lashan Peiris, Rahim Valji, Simon Turner, Kieran Purich, Kevin Verhoeff, Brett Mador, Steffane McLennan, Ali Safar, Atif Jastaniah, Morgan Schellenberg, Natthida Owattanapanich, Areg Grigorian, Lydia Lam, Jeffry Nahmias, Kenji Inaba, Morgan Schellenberg, Panagiotis Liasidis, Kenji Inaba, Demetrios Demetriades, Morgan Schellenberg, Elizabeth R Benjamin, Shaun Cowan, Natthida Owattanapanich, Monica D Wong, Kenji Inaba, Demetrios Demetriades, Morgan Schellenberg, Natthida Owattanapanich, Brent Emigh, Lindsey Karavites, Damon H Clark, Lydia Lam, Kenji Inaba, Morgan Schellenberg, Elizabeth R Benjamin, Natthida Owattanapanich, Kenji Inaba, Demetrios Demetriades, Morgan Schellenberg, Geoffrey A Anderson, Natthida Owattanapanich, Vincent Cheng, Lydia Lam, Kenji Inaba, Lee Myers, Julian Daza, Brian Cuthbertson, Paul Myles, Mark Shulman, Duminda Wijeysundera, Lyndsay T Glass, Patrick B Murphy, Laura Allen, Kathryn Minkhorst, Dillon Bowker, Ephraim S Tang, Kenneth Leslie, Jeffrey E Hawel, Kevin Verhoeff, Odelle Ma, Kieran Purich, Samuel Skinner, Raveena Dhaliwal, Matt Strickland, Garrett Johnson, Jason Park, Ashley Vergis, Lawrence Gillman, Justin Rivard, Keegan Guidolin, Justin Lin, Anudari Zorigtbaatar, Minahil Nadeem, Tarek Ibrahim, Zdenka Neilson, Kyung Young Peter Kim, Luckshi Rajendran, Sami Chadi, Fayez Quereshy, Lyndsay T Glass, Malcolm Davidson, Emily Friedrich, Caitlin Champion, Saba Balvardi, Koorosh Semsar-Kazerooni, Pepa Kaneva, Carmen Mueller, Melina Vassiliou, Mohammed Al Mahroos, Julio Fiore, Kevin Schwartzman, Liane Feldman, Nada Gawad, Kieran Purich, Kevin Verhoeff, Blaire Anderson, Tyler McKechnie, Ryan Daniel, Colin Kruse, Marc Levin, Yung Lee, Aristithes Doumouras, Dennis Hong, Cagla Eskicioglu, Tyler McKechnie, Christopher Povolo, Jay Lee, Yung Lee, Lily Park, Aristithes Doumouras, Dennis Hong, Mohit Bhandari, Cagla Eskicioglu, Kieran Purich, Esther Lee, Kevin Verhoeff, Dasan Sydora, Simon Turner, Matt Strickland, Jessica Henley, Darrell Boone, Stephanie Roberts, Emma Imbert, Duncan McGrouther, Paul Manuel, Christine Li, Mark Dykstra, Haili Wang, Ryan Snelgrove, Samuel Skinner, Kevin Verhoeff, Kieran Purich, Troy Perry, Matthew Strickland, Raveena Dhaliwal, Tori Lenet, Stephanie Skanes, Joseph Tropiano, Daniel McIsaac, Alan Tinmouth, Julie Hallet, Stuart Nicholls, Dean Fergusson, Guillaume Martel, Tori Lenet, Joseph Tropiano, Stephanie Skanes, Victoria Ivankovic, Daniel McIsaac, Alan Tinmouth, Andrea Patey, Dean Fergusson, Guillaume Martel, Jeff Metz, Reza Naqvi, Ruediger Noppens, Jeff Hawel, Ahmad Elnahas, Christopher Schlachta, Nawar Alkhamesi, Hilalion San Ahn, Tori Lenet, Richard Gilbert, Ranjeeta Mallick, Julie Shaw, Daniel McIsaac, Guillaume Martel, Uyen Do, Makena Pook, Tahereh Najafi, Fateme Rajabiyazdi, Charbel El-Kefraoui, Saba Balvardi, Natasha Barone, Hiba Elhaj, Philip Nguyen-Powanda, Lawrence Lee, Gabriele Baldini, Liane Feldman, Julio Fiore, Armin Rouhi, Kieran Purich, Uzair Jogiat, Deng Mapiour, Michael Kim, Brianna Greenberg, Ashlie Nadler, Hala Muaddi, Theres Stukel, Charles De Mestral, Avery Nathens, Stephen Pautler, Bobby Shayegan, Wael Hanna, Christopher Schlachta, Rodney Breau, Laura Hopkins, Timothy Jackson, Paul Karanicolas, Lily Park, Christopher Griffiths, Sam Ali, Victoria Archer, Zacharie Cloutier, Dexter Choi, Tyler McKechnie, Pablo Serrano, Kelly Vogt, J Andrew McClure, Philip Jones, Marko Mrkobrada, Suzanne Flier, Blayne Welk, Luc Dubois, Nori Bradley, Kosar Khwaja, Laura Allen, Lily Tung, Morad Hameed, Karina Spoyalo, Jacinthe Lampron, Carlos Garcia-Ochoa, Atif Jastaniah, Paul Engels, Gaurav Talwar, Zacharie Cloutier, Sam Minor, Brad Moffat, Neil Parry, Kelly Vogt, Shirley Xiaoxuan Deng, Tega Ebeye, Bree T Sharma, Anas Samman, Amna Zulfiqar, Roderick H Purzner, Brittany Greene, Melanie Tsang, Shiva Jayaraman, Patrick Murphy, Laura Allen, Chad G Ball, Morad Hameed, Paul Engels, Rahima Nenshi, Sandy Widder, Sam Minor, Neil Parry, Nori Bradley, Brad Moffat, Kelly Vogt, Mostafa Alhabboubi, Sender Liberman, Evan Wong, Talat Chughtai, Joel Turner, Jessica Lie, Sam Wiseman, Jennifer Li, Nicole Mak, Simon Laplante, Babak Namazi, Parmiss Kiani, Daniel Hashimoto, Adnan Alseidi, Mauricio Pasten, L Michael Brunt, Sujata Gill, Brian Davis, Matthew Bloom, Luise Pernar, Allan Okrainec, Amin Madani, Jessica Lie, Trevor Hamilton, Kylie Nabata, Jenny W Zhang, Darren Zhao, Phil Dawe, Morad Hameed, Jeremy Drung, Laura Allen, Ken Leslie, Jeremy Drung, Thomas Nixon, Kieran Purich, Kevin Verhoeff, Samuel Skinner, Raveena Dhaliwal, Matt Strickland, Alexandra Allard-Coutu, Barbara Heller, Victoria Wright, Wanjae Cho, Michael Wong, Kevin Singh, Sarah Mansouri, Émilie Comeau, Yves Collin, Sonia Cheng Oviedo, Alex Lee, Luckshi Rajendran, Tyler Lamb, Morgann Reid, Anastasia Turner, Kimberly Bertens, Janelle Rekman, Fady Balaa, Jillian Tweedy, Katerina Neumann, Geoff Porter, Michael A D'Elia, Iris Teo, Catherine L Forse, Reilly Musselman, Brent Hopkins, Lily Grozman, Nawaf Alshawan, Shannon Fraser, Simon Bergman, Jean-Sebastien Pelletier, Tsafrir Vanounou, Evan G Wong, Ananya Srivastava, Brodie Nolan, Lyon Qiao, James Jung, Kameela Alibhai, Isabelle Raîche, Heather McDonald, Nada Gawad, Christina Lee, Rona Cheifetz, Philippa Hawley, Jeongyoon Jenny Moon, Zachary Rehany, Mehrshad Bakhshi, Tarek Razek, Jeremy Grushka, Nathalie Boulanger, Larry Watt, Alexandra Vivier, Greg Clark, Paola Fata, Dan Deckelbaum, Kosar Khwaja, Atif Jastaniah, Evan Wong, Nathan How, Kevin Ren, Yuan Qiu, Karyssa Hamann, Karina Spoyalo, Annie Lalande, Andrea MacNeill, Jason Park, Annie Lalande, Stephanie Alexis, Karina Spoyalo, Keiko Patterson, Neha Gadhari, Jiaying Zhao, Andrea MacNeill, Zarrukh Baig, Rubia Ahmed, Ameer Farooq, Ahmer Karimuddin, Christina Schweitzer, Sam Wiseman, Joshua Keogh, Allison Chhor, Housne Begum, Noori Akhtar-Danesh, Christian Finley, Bright Huo, Daria Manos, Zhaolin Xu, Kara Matheson, Samuel Chun, John Fris, Alison Wallace, Daniel French, Yogita S Patel, Jean-Marc Baste, Yaron Shargall, Thomas K Waddell, Kazuhiro Yasufuku, Tiago N Machuca, Feng Xie, Lehana Thabane, Wael C Hanna, Yogita S Patel, Marla K Beauchamp, Joshua Wald, Lawrence Mbuagbaw, Brenda L Key, Sheryl M Green, Wael C Hanna, Uzair Jogiat, Abdollah Behzadi, Laura Donahoe, Awrad Nasralla, Julius Poon, Najib Safieddine, Nazgol Seyednejad, Iran Tavakoli, Simon Turner, Anna L McGuire, Sohat Sharma, Roy A Hilzenrat, Melissa McConechy, Ingrid Frank, Curtis Hughsman, Stephen Yip, James J Choi, John Yee, Uzair Jogiat, Hannah Sasewich, Simon Turner, Vickie Baracos, Dean Eurich, Heather Filafilo, Eric Bedard, Yung Lee, Yasith Samarasinghe, Janhavi Patel, Adree Khondker, Tyler McKechnie, Nadeesha Samarasinghe, Christian Finley, Wael Hanna, Yaron Shargall, John Agzarian, Evan Barber, Melissa Whidden, Francisco Aguirre, Andrew Graham, Gileh-Gol Akhtar-Danesh, Allison Chhor, Housne Begum, Joycelyne Ewusie, Lawrence Mbuagbaw, Shargall Yaron, Adom Bondzi-Simpson, Melanie Keshishi, Yonas Ademe, Ayalew Tizazu, Marci Rose, Sameena Uddin, Michael Ko, Riley Bowker, Jimmy Ddamba, Daniel French, Alison Wallace, Negar Ahmadi, Najib Safieddine, Sayf Gazala, Carmine Simone, Sami A Abdul, Frances Wright, Christian Finley, Patrick J Villeneuve, Sebastian Gilbert, Sudhir Sundaresan, Andrew J E Seely, Donna E Maziak, Pooja Patel, Daria Manos, Alison Wallace, Madelaine Plourde, Lyndsay Harrison, Donna Turner, Jolie Ringash, Douglas Manuel, Biniam Kidane, Vaibhav Gupta, Kathleen Decker, Laura Davis, Gail Darling, Carolyn Compton, Natalie Coburn, Randy Boyes, Michael Pugliese, Alyson Mahar, Amy Hsu, Ge Shi, Andrew Kokavec, Edward Ho, Ryan Waterman, Edward Wang, Kiera Harnden, Richard Malthaner, Rahul Nayak, Mehdi Qiabi, Ge Shi, Richard Malthaner, Rahul Nayak, Mehdi Qiabi, Jacob A Alaichi, Yogita Patel, Forough Farrokhyar, Marko Simunovic, Wael C Hanna, Biniam Kidane, Stephen Gowing, Richard Liu, Sadeesh Srinathan, Larry Tan, Linda Chang Qu, Richard Malthaner, Jacob Alaichi, Peter Malik, Yogita Patel, Wael Hanna, Emily Mackay, Umeed Fahim, Ajmal Hafizi, Ahmad S Ashrafi, Jay Lee, Tyler McKechnie, Nalin Amin, Aristithes Doumouras, Dennis Hong, Cagla Eskicioglu, Kieran Purich, Courtney Streu, Clarence Wong, Dan Schiller, Matthew Castelo, Colin Sue-Chue-Lam, Lawrence Paszat, Adena Scheer, Bettina Hansen, Teruko Kishibe, Nancy Baxter, Antonio Caycedo-Marulanda, Emma Neary, Tarek Ibrahim, Chris Verschoor, Sunil Patel, Shaila Merchant, Sami Chadi, Luis Romagnolo, Antonio Caycedo-Marulanda, Chris Verschoor, Carl Brown, Ahmer Karimuddin, Manoj Raval, Terry Phang, Elena Vikis, George Melich, Sunil Patel, Kelly Brennan, Sunil Patel, Antonio Caycedo-Marulanda, Shaila Merchant, Christopher Booth, Weidong Kong, Chad McClintock, Clare Bankhead, Carl Heneghan, Kelly Brennan, Sunil Patel, Chad McClintock, Shaila Merchant, Antonio Caycedo-Marulanda, Christopher Booth, Clare Bankhead, Carl Heneghan, Kelly Brennan, Lisa Zhang, Jennifer Flemming, Maya Djerboua, Sulaiman Nanji, Antonio Caycedo-Marulanda, Shaila Merchant, Sunil Patel, Richard Garfinkle, Marie Demian, Sarah Sabboobeh, Jeongyoon Moon, Michael Hulme-Moir, A Sender Liberman, Stan Feinberg, Dana M Hayden, Sami A Chadi, Sebastian Demyttenaere, Louise Samuel, Nevart Hotakorzian, Laurence Quintin, Nancy Morin, Gabriela Ghitulescu, Julio Faria, Carol-Ann Vasilevsky, Marylise Boutros, Sahil Sharma, Tyler Mckechnie, Jigish Khamar, Simarpreet Ichhpuniani, Cagla Eskicioglu, Sydney Candy, Sunil Patel, Shaila Merchant, Antonio Caycedo-Marulanda, Clare Bankhead, Carl Heneghan, Tyler McKechnie, Shaylan Govind, Jay Lee, Yung Lee, Dennis Hong, Cagla Eskicioglu, Tyler McKechnie, Justin Lu, Jigish Khamar, Yung Lee, Nalin Amin, Dennis Hong, Cagla Eskicioglu, Tyler McKechnie, Luisa Cardenas, Daniel Schep, Aristithes Doumouras, Dennis Hong, Raimond Wong, Oren Levine, Cagla Eskicioglu, Lawrence Lee, Carmen Mueller, Barry Stein, Patrick Charlebois, Sender Liberman, Gerald Fried, Liane Feldman, Stephan Robitaille, Anna Wang, Sender Liberman, Patrick Charlebois, Barry Stein, Julio F Fiore, Liane Feldman, Lawrence Lee, Stephan Robitaille, Anna Wang, Sender Liberman, Patrick Charlebois, Barry Stein, Julio F Fiore, Liane Feldman, Lawrence Lee, Hamid Sadri, Alan Barkun, Sydney Selznick, Jordan Levy, Ruxandra Bogdan, Jeffrey Hawel, Ahmad Elnahas, Nawar A Alkhamesi, Christopher M Schlachta, Vanessa Wiseman, Antonio Caycedo-Marulanda, Natasha Iaboni, David Hurlbut, Martin Kaufmann, Kevin Yi Mi Ren, Amoon Jamzad, Parvin Mousavi, Gabor Fichtinger, Christopher J B Nicol, John F Rudan, Vanessa Wiseman, Kelly Brennan, Antonio Caycedo-Marulanda, Shaila Merchant, Chad McClintock, Sunil V Patel, Vanessa Wiseman, Chad McClintock, Clare Bankhead, Shaila Merchant, Antonio Caycedo-Marulanda, Chris Booth, Carl Heneghan, Kelly Brennan, Lisa Zhang, Bright Huo, Alexandra Donaldson, Jennifer Flemming, Sulaiman Nanji, Antonio Caycedo-Marulanda, Shaila Merchant, Susan Brogly, Sunil Patel, Laura Baker, Tori Lenet, Lily Park, Sanjay Murthy, Reilly Musselman, Simarpreet Ichhpuniani, Tyler McKechnie, Jay Lee, Jeremy Biro, Yung Lee, Lily Park, Aristithes Doumouras, Dennis Hong, Cagla Eskicioglu, Garrett Johnson, Harminder Singh, Ramzi Helewa, Kristin Reynolds, Kathryn Sibley, Malcolm Doupe, Lisa Zhang, Kelly Brennan, Jennifer Flemming, Sulaiman Nanji, Shaila Merchant, Maya Djerboua, Antonio Caycedo-Marulanda, Sunil Patel, James Holden, Garrett Johnson, David Hochman, Ramzi Helewa, Jeongyoon Jenny Moon, Richard Garfinkle, Sophie Dell'Aniello, Phyllis Zelkowitz, Carol-Ann Vasilevsky, Paul Brassard, Marylise Boutros, Jeongyoon Jenny Moon, Amine Zoughlami, Wusiman Abibula, Alex Amar, Gabriela Ghitulescu, Carol-Ann Vasilevsky, Paul Brassard, Marylise Boutros, Jeongyoon Jenny Moon, Théa Araji, Allison Pang, Carol-Ann Vasilevsky, Marylise Boutros, Jeongyoon Jenny Moon, Alexa Ehlebracht, Julio Faria, Gabriela Ghitulescu, Nancy Morin, Allison Pang, Carol-Ann Vasilevsky, Marylise Boutros, Tiffany Paradis, Stephan Robitaille, Mahalia Oliver, Patrick Charlebois, Barry Stein, Sender Liberman, Liane S Feldman, Lawrence Lee, Zubair Bayat, Erin Kennedy, Charles Victor, Anand Govindarajan, Sunil Patel, Lisa Zhang, Kelly Brennan, Maya Djerboua, Sulaiman Nanji, Shaila J Merchant, Antonio Caycedo-Marulanda, Jennifer Flemming, Michael Fares Maalouf, Stephan Robitaille, Ruxandra Penta, Makena Pook, Julio Flavio Fiore, Liane Feldman, Lawrence Lee, Alon Wachtel, Nathalie Wong-Chong, Daniel Marinescu, Sahir Bhatnagar, Nancy Morin, Gabriela Ghitulescu, Carol-Ann Vasilevsky, Julio Faria, Marylise Boutros, Victoria Baronas, Arif Arif, Gale Ladua, Eric Bhang, Carl Brown, Fergal Donellan, Heather Stuart, Jonathan Loree, Vanessa Wiseman, Sunil Patel, Lisa Zhang, Peter Hugh MacDonald, Shaila Merchant, Kathleen Wattie Barnett, Antonio Caycedo-Marulanda, Jessica Lie, Carl Brown, Ahmer Karimuddin, Heather Stuart, Amandeep Ghuman, Terry Phang, Manoj Raval, Hyea Min Yoon, Roy Hajjar, Gabriela Fragoso, Manon Oliero, Annie Calvé, Hervé Vennin Rendos, Emmanuel Gonzalez, Nicholas J B Brereton, Thibault Cuisiniere, Claire Gerkins, Souad Djediai, Borhane Annabi, Khoudia Diop, Bertrand Routy, Patrick Laplante, Jean-François Cailhier, Nassima Taleb, Hefzi Alratrout, François Dagbert, Rasmy Loungnarath, Herawaty Sebajang, Frank Schwenter, Ramses Wassef, Richard Ratelle, Eric Debroux, Carole Richard, Manuela M Santos, Alexa Ehlebracht, Doulia Hamad, Hatim Alsulaim, Olivia Monton, Daniel Marinescu, Allison Pang, Carol-Ann Vasilevsky, Marylise Boutros, Natasha Caminsky, Daniel Marinescu, Mohammed Alqahtani, Allison Pang, Gabriela Ghitulescu, Carol-Ann Vasilevsky, Marylise Boutros, Natasha Caminsky, Daniel Marinescu, Richard Garfinkle, Marylise Boutros, Richard Gilbert, Terry Zwiep, Joshua Greenberg, Tori Lenet, Reilly Musselman, Lara Williams, Isabelle Raiche, Daniel McIsaac, Kednapa Thavorn, Dean Fergusson, Husein Moloo, Geneviève Morin, Janyssa Charbonneau, Xavier Paré, Jonathan Frigault, François Letarte, Rebecca C Auer, Michael Ott, Paul Karanicolas, Muriel Brackstone, Shady Ashmalla, Joel Weaver, Vicky Tagalakis, Marylise Boutros, Peter Stotland, Antonio Caycedo-Marulanda, Husein Moloo, Shiva Jayaraman, Sunil Patel, Gregoire LeGal, Silvana Spadafora, Steven Maclellan, Daniel Trottier, Derek Jonker, Timothy Asmis, Ranjeeta Mallick, Timothy Ramsay, Marc Carrier, Terry Phang, Delaram Shojaei, Ali Motamedi, Anu Ghuman, Ahmer Karimuddin, Manoj Raval, Carl Brown, Delaram Shojaei, Jessica Hopkins, Haili Wang, Don Buie, Jessica Hopkins, Haili Wang, Don Buie, Yosef Levin, Nasra Al Busaidi, Fateme Rajabiyazdi, Marie Demian, Marylise Boutros, Armaghan Alam, Ameer Farooq, Carl Brown, Terry Phang, Amandeep Ghuman, Ahmer Karimuddin, Manoj Raval, Farhad Udwadia, Natasha Caminsky, Daniel Marinescu, Mohammed Alqahtani, Allison Pang, Carol-Ann Vasilevsky, Marylise Boutros, Sarah Mansouri, Sonia Cheng Oviedo, Nathalie McFadden, Philip Lagace, Richard Spence, Greg Hirsch, Katerina Neumann, Philip Lagace, Katerina Neumann, Richard Spence, Charbel El-Kefraoui, Garrett Johnson, Harminder Singh, Ramzi Helewa, Marguerite Mainprize, Ayse Yilbas, Fernando Spencer Netto, Joel Katz, Megan Melland-Smith, Bree Sharma, Usman Khan, Markus Selzner, Kevin Verhoeff, Valentin Mocanu, Jerry Dang, Hillary Wilson, Noah Switzer, Daniel Birch, Shahzeer Karmali, Kevin Verhoeff, Valentin Mocanu, Uzair Jogiat, Hayley Forbes, Noah Switzer, Daniel Birch, Shahzeer Karmali, Khadija Nasser, Kevin Verhoeff, Valentin Mocanu, Janice Kung, Kieran Purich, Noah Switzer, Daniel Birch, Shahzeer Karmali, Olivier Mailloux, Nicolas Tassé, André Tchernof, Mélanie Nadeau, Philip Dawe, Andrew Beckett, Laurent Biertho, Kieran Purich, Andrea Lin, Kevin Verhoeff, Valentin Mocanu, Janice Y Kung, Daniel W Birch, Shahzeer Karmali, Noah J Switzer, Marta Whyte, Melinda Fowler-Woods, Amanda Fowler-Woods, Geraldine Shingoose, Andrew Hatala, Felicia Daeninck, Ashley Vergis, Krista Hardy, Kathleen Clouston, Ting Li, Estifanos Debru, Mirza Shaharyar Ahmad, Warren Sun, Jerry Dang, Noah Switzer, Daniel Birch, Shahzeer Karmali, Christopher De Gara, Warren Sun, Jennifer Halasz, Jerry Dang, Noah Switzer, Aliyah Kanji, Daniel Birch, Renuca Modi, Shahzeer Karmali, Hilalion San Ahn, Jeffrey Gu, Amer Jarrar, Nicole Kolozsvari, Yung Lee, Yasith Samarasinghe, Lucy Chen, Akithma Hapugall, Arshia Javidan, Tyler McKechnie, Aristithes Doumouras, Dennis Hong, Eileen Roach, Simon Laplante, Shannon Stogryn, Azusa Maeda, Timothy Jackson, Allan Okrainec, Alexandra Chow, Daniel Birch, Shahzeer Karmali, Aliyah Kanji, Noah Switzer, Jessica Trac, Michael Balas, Denise Gee, Matthew Hutter, Ozanan Meireles, James Jung, Wenjing He, Ashley Vergis, Krista Hardy, Karim Ramji, Vanessa Boudreau, Dennis Hong, Mehran Anvari, Pouya Iranmanesh, Karen Barlow, Tyler Cookson, Rafik Bolis, Harsha Shanthanna, Jonah Shiroky, Ekaterina Kouzmina, Shaidah Deghan, Boris Zevin, Cypriana Koziak, Zacharie Cloutier, Tyler Cookson, Karen Barlow, Vanessa Boudreau, Mehran Anvari, Intekhab Hossain, Jane Brodie, Erin O'Brien, Katherine Tedman-Aucoin, Diana Lawlor, Raleen Murphy, Laurie Twells, David Pace, James Ellsmere, Bradley Evans, Valentin Mocanu, Terry Zhang, Edward Deehan, Dina Kao, Naomi Hotte, Daniel Birch, Shahzeer Karmali, Kalutota Samarasinghe, Jens Walter, Karen Madsen, Nader Hanna, Erin Williams, Weidong Kong, Adam Fundytus, Christopher Booth, Sunil Patel, Antonio Caycedo-Marulanda, Wiley Chung, Sulaiman Nanji, Shaila Merchant, Matthew Castelo, Bettina Hansen, Lawrence Paszat, Nancy Baxter, Adena Scheer, Makena Pook, Tahereh Najafi Ghezeljeh, Maxime Lapointe-Gagner, Philip Nguyen-Powanda, Hiba Elhaj, Fateme Rajabiyazdi, Lawrence Lee, Liane S Feldman, Julio Fiore, Jesse Zuckerman, Rinku Sutradhar, Barbara Haas, Matthew Guttman, Antoine Eskander, Natalie Coburn, Tyler Chesney, Bourke Tillman, Victoria Zuk, Alyson Mahar, Amy Hsu, Wing Chan, Julie Hallet, Woo Jin Choi, Keegan Guidolin, Filomena Servidio-Italiano, Fayez Quereshy, Gonzalo Sapisochin, Akie Watanabe, Eitan Prisman, Elliot Mitmaker, Ross Walker, Jonn Wu, Anne Nguyen, Sam Wiseman, Bianka Saravana-Bawan, Dennis Hong, Michael Gupta, Jesse Pasternak, David Cyr, Omar Vergara-Fernandez, Amanpreet Brar, James Conner, Richard Kirsch, Mantaj Brar, Erin Kennedy, Anand Govindarajan, Robert Gryfe, Helen MacRae, Zane Cohen, Robin McLeod, Carol Swallow, Muriel Brackstone, Farhad Ghasemi, Victoria Ivankovic, Megan Delisle, Dawn Stacey, Jad Abou-Khalil, Fady Balaa, Kimberly Bertens, Brittney Dingley, Guillaume Martel, Kristen McAlpine, Carolyn Nessim, Shaheer Tadros, Marc Carrier, Rebecca Auer, Ananya Gopika Nair, David Lim, Dhruvin Hirpara, Antoine Eskander, Natalie Coburn, Rinku Sutradhar, Wing Chan, Julie Hallet, Cecily Stockley, Felicia Pickard, Alexander Mathieson, Michael Hogan, Melanie Seal, Deanna Ng, Belkacem Acidi, Wendy Johnston, Dario Callegaro, Savtaj Brar, Rebecca Gladdy, Peter Chung, Charles Catton, Korosh Khalili, Charles Honore, Carol Swallow, Shelly Luu, Ning Fu, Karineh Kazazian, Karina Pacholczyk, Deanna Ng, Jossie Swett-Cosentino, Paul Savage, Yukiko Shibahara, Sangeetha Kalimuthu, Osvaldo Espin-Garcia, James Conner, Jonathan Yeung, Gail Darling, Carol Swallow, Léamarie Meloche-Dumas, Frédéric Mercier, Victoria Barabash, Calvin Law, Natalie Coburn, Simron Singh, Sten Myrehaug, Wing Chan, Julie Hallet, Michael A D'Elia, Rebecca C Auer, Ashley Eom, Narry Muhn, Barbara Heller, Peter Lovrics, Katelynn Tang, Shawn Khan, Deanna Ng, Daniel Koerber, Eisar Al-Sukhni, David Cyr, Karineh Kazazian, Carol Swallow, Erika Schmitz, Sameer Apte, Carolyn Nessim, Ko Ta Chen, Judy Ban, Leo Chen, Elaine McKevitt, Rebecca Warburton, Jin-Si Pao, Carol Dingee, Urve Kuusk, Amy Bazzarelli, Jieun Newman-Bremang, Nicole Look Hong, Anna Gagliardi, Bryanna Nyhof, Kevin Verhoeff, Braulio Marfil-Garza, Gurpal Sandha, David Cooper, Khaled Dajani, David Bigam, Blaire Anderson, Tatsuya Kin, Anna Lam, Doug O'Gorman, Peter Senior, Camillo Ricordi, A M James Shapiro, Nic Jette, Michael Moser, Zuhaib Mir, Henry Lam, Jennifer Flemming, Diederick Jalink, Sulaiman Nanji, Sean Bennett, Christopher Griffiths, Betty Zhang, Kasia Tywonek, Brandon Meyers, Pablo Serrano, Luckshi Rajendran, Tori Lenet, Risa Shorr, Jad Abou-Khalil, Kimberly Bertens, Fady Balaa, Guillaume Martel, Jesse Zuckerman, Shiva Jayaraman, Alice Wei, Alyson Mahar, Yosuf Kaliwal, Guillaume Martel, Natalie Coburn, Julie Hallet, Woo Jin Choi, Phil Williams, Marco Claasen, Tommy Ivanics, Marina Englesakis, Steven Gallinger, Bettina Hansen, Gonzalo Sapisochin, Woo Jin Choi, Tommy Ivanics, Marco Claasen, Steven Gallinger, Bettina Hansen, Gonzalo Sapisochin, Richard Gilbert, Tori Lenet, Jad Abou-Khalil, Fady Balaa, Guillaume Martel, Alexandre Brind'Amour, Kimberly Bertens, Tori Lenet, Fady Balaa, Kimberly Bertens, Guillaume Martel, Jad Abou-Khalil, Nawal Amhis, Yves Collin, Marco Claasen, Tommy Ivanics, Christian Toso, Rene Adam, Jan Ijzermans, Gonzalo Sapisochin, Wojtek Polak, Sarah Mansouri, Maxime Léveillé, Christine Lawson, Yves Collin, Lee-Hwa Tai, Adriana Workewych, Brittany Greene, Shiva Jayaraman, Melanie Tsang, Alex Lee, Ahmed Al-Arnawoot, Luckshi Rajendran, Tyler Lamb, Anastasia Turner, Morgann Reid, Janelle Rekman, Richard Mimeault, Jad Abou-Khalil, Kimberly Bertens, Guillaume Martel, Fady Balaa, Evelyn Waugh, Chris Zhang, Madeline Lemke, Juan Glinka, Ken Leslie, Anton Skaro, Ephraim Tang, Alice Zhu, Brittany Greene, Melanie Tsang, Shiva Jayaraman, Helia Nabavian, Lev Bubis, Shiva Jayaraman, Melanie E Tsang, Jorge Roldan, Olivia Ganescu, Tsafrir Vanounou, Jean-Sébastien Pelletier, Andrew Lagrotteria, Brittany Greene, Melanie Tsang, Shiva Jayaraman, Jorge Roldan, Olivia Ganescu, Jean-Sébastien Pelletier, Tsafrir Vanounou, Luckshi Rajendran, Woo Jin Choi, Hala Muaddi, Tommy Ivanics, Marco P A W Classen, Gonzalo Sapisochin
No abstract text is available yet for this article.
2022: Canadian Journal of Surgery. Journal Canadien de Chirurgie
https://read.qxmd.com/read/34695550/the-effect-of-diabetes-on-abdominal-aortic-aneurysm-growth-over-2-years
#10
JOURNAL ARTICLE
Matthew J Nordness, B Timothy Baxter, Jon Matsumura, Michael Terrin, Kevin Zhang, Fei Ye, Nancy R Webb, Ronald L Dalman, John A Curci
OBJECTIVE: Abdominal aortic aneurysm (AAA) is a common progressive disease and a significant cause of morbidity and mortality. Prior investigations have shown that diabetes mellitus (DM) may be relatively protective of AAA incidence and growth. The Non-invasive Treatment of Aortic Aneurysm Clinical Trial (N-TA3 CT) is a contemporary study of small AAA growth that provides a unique opportunity to validate and explore the effect of DM on AAA. Confirming the effect of DM on AAA growth in this study may present opportunities to explore for clues to potential biologic mechanisms as well as inform current patient management...
October 23, 2021: Journal of Vascular Surgery
https://read.qxmd.com/read/34655683/role-of-volume-in-small-abdominal-aortic-aneurysm-surveillance
#11
JOURNAL ARTICLE
Sydney L Olson, Annalise M Panthofer, William Blackwelder, Michael L Terrin, John A Curci, B Timothy Baxter, Fred A Weaver, Jon S Matsumura
OBJECTIVE: Current management of small abdominal aortic aneurysms (AAAs) primarily involves serial imaging surveillance of maximum transverse diameter (MTD) to estimate rupture risk. Other measurements, such as volume and tortuosity, are less well-studied and may help characterize and predict AAA progression. This study evaluated predictors of AAA volume growth and discusses the role of volume in clinical practice. METHODS: Subjects from the Non-invasive Treatment of Abdominal Aortic Aneurysm Clinical Trial (baseline AAA MTD, 3...
April 2022: Journal of Vascular Surgery
https://read.qxmd.com/read/34593819/austraits-a-curated-plant-trait-database-for-the-australian-flora
#12
JOURNAL ARTICLE
Daniel Falster, Rachael Gallagher, Elizabeth H Wenk, Ian J Wright, Dony Indiarto, Samuel C Andrew, Caitlan Baxter, James Lawson, Stuart Allen, Anne Fuchs, Anna Monro, Fonti Kar, Mark A Adams, Collin W Ahrens, Matthew Alfonzetti, Tara Angevin, Deborah M G Apgaua, Stefan Arndt, Owen K Atkin, Joe Atkinson, Tony Auld, Andrew Baker, Maria von Balthazar, Anthony Bean, Chris J Blackman, Keith Bloomfield, David M J S Bowman, Jason Bragg, Timothy J Brodribb, Genevieve Buckton, Geoff Burrows, Elizabeth Caldwell, James Camac, Raymond Carpenter, Jane A Catford, Gregory R Cawthray, Lucas A Cernusak, Gregory Chandler, Alex R Chapman, David Cheal, Alexander W Cheesman, Si-Chong Chen, Brendan Choat, Brook Clinton, Peta L Clode, Helen Coleman, William K Cornwell, Meredith Cosgrove, Michael Crisp, Erika Cross, Kristine Y Crous, Saul Cunningham, Timothy Curran, Ellen Curtis, Matthew I Daws, Jane L DeGabriel, Matthew D Denton, Ning Dong, Pengzhen Du, Honglang Duan, David H Duncan, Richard P Duncan, Marco Duretto, John M Dwyer, Cheryl Edwards, Manuel Esperon-Rodriguez, John R Evans, Susan E Everingham, Claire Farrell, Jennifer Firn, Carlos Roberto Fonseca, Ben J French, Doug Frood, Jennifer L Funk, Sonya R Geange, Oula Ghannoum, Sean M Gleason, Carl R Gosper, Emma Gray, Philip K Groom, Saskia Grootemaat, Caroline Gross, Greg Guerin, Lydia Guja, Amy K Hahs, Matthew Tom Harrison, Patrick E Hayes, Martin Henery, Dieter Hochuli, Jocelyn Howell, Guomin Huang, Lesley Hughes, John Huisman, Jugoslav Ilic, Ashika Jagdish, Daniel Jin, Gregory Jordan, Enrique Jurado, John Kanowski, Sabine Kasel, Jürgen Kellermann, Belinda Kenny, Michele Kohout, Robert M Kooyman, Martyna M Kotowska, Hao Ran Lai, Etienne Laliberté, Hans Lambers, Byron B Lamont, Robert Lanfear, Frank van Langevelde, Daniel C Laughlin, Bree-Anne Laugier-Kitchener, Susan Laurance, Caroline E R Lehmann, Andrea Leigh, Michelle R Leishman, Tanja Lenz, Brendan Lepschi, James D Lewis, Felix Lim, Udayangani Liu, Janice Lord, Christopher H Lusk, Cate Macinnis-Ng, Hannah McPherson, Susana Magallón, Anthony Manea, Andrea López-Martinez, Margaret Mayfield, James K McCarthy, Trevor Meers, Marlien van der Merwe, Daniel J Metcalfe, Per Milberg, Karel Mokany, Angela T Moles, Ben D Moore, Nicholas Moore, John W Morgan, William Morris, Annette Muir, Samantha Munroe, Áine Nicholson, Dean Nicolle, Adrienne B Nicotra, Ülo Niinemets, Tom North, Andrew O'Reilly-Nugent, Odhran S O'Sullivan, Brad Oberle, Yusuke Onoda, Mark K J Ooi, Colin P Osborne, Grazyna Paczkowska, Burak Pekin, Caio Guilherme Pereira, Catherine Pickering, Melinda Pickup, Laura J Pollock, Pieter Poot, Jeff R Powell, Sally A Power, Iain Colin Prentice, Lynda Prior, Suzanne M Prober, Jennifer Read, Victoria Reynolds, Anna E Richards, Ben Richardson, Michael L Roderick, Julieta A Rosell, Maurizio Rossetto, Barbara Rye, Paul D Rymer, Michael A Sams, Gordon Sanson, Hervé Sauquet, Susanne Schmidt, Jürg Schönenberger, Ernst-Detlef Schulze, Kerrie Sendall, Steve Sinclair, Benjamin Smith, Renee Smith, Fiona Soper, Ben Sparrow, Rachel J Standish, Timothy L Staples, Ruby Stephens, Christopher Szota, Guy Taseski, Elizabeth Tasker, Freya Thomas, David T Tissue, Mark G Tjoelker, David Yue Phin Tng, Félix de Tombeur, Kyle Tomlinson, Neil C Turner, Erik J Veneklaas, Susanna Venn, Peter Vesk, Carolyn Vlasveld, Maria S Vorontsova, Charles A Warren, Nigel Warwick, Lasantha K Weerasinghe, Jessie Wells, Mark Westoby, Matthew White, Nicholas S G Williams, Jarrah Wills, Peter G Wilson, Colin Yates, Amy E Zanne, Graham Zemunik, Kasia Ziemińska
We introduce the AusTraits database - a compilation of values of plant traits for taxa in the Australian flora (hereafter AusTraits). AusTraits synthesises data on 448 traits across 28,640 taxa from field campaigns, published literature, taxonomic monographs, and individual taxon descriptions. Traits vary in scope from physiological measures of performance (e.g. photosynthetic gas exchange, water-use efficiency) to morphological attributes (e.g. leaf area, seed mass, plant height) which link to aspects of ecological variation...
September 30, 2021: Scientific Data
https://read.qxmd.com/read/34108472/determinants-of-penetrance-and-variable-expressivity-in-monogenic-metabolic-conditions-across-77-184-exomes
#13
JOURNAL ARTICLE
Julia K Goodrich, Moriel Singer-Berk, Rachel Son, Abigail Sveden, Jordan Wood, Eleina England, Joanne B Cole, Ben Weisburd, Nick Watts, Lizz Caulkins, Peter Dornbos, Ryan Koesterer, Zachary Zappala, Haichen Zhang, Kristin A Maloney, Andy Dahl, Carlos A Aguilar-Salinas, Gil Atzmon, Francisco Barajas-Olmos, Nir Barzilai, John Blangero, Eric Boerwinkle, Lori L Bonnycastle, Erwin Bottinger, Donald W Bowden, Federico Centeno-Cruz, John C Chambers, Nathalie Chami, Edmund Chan, Juliana Chan, Ching-Yu Cheng, Yoon Shin Cho, Cecilia Contreras-Cubas, Emilio Córdova, Adolfo Correa, Ralph A DeFronzo, Ravindranath Duggirala, Josée Dupuis, Ma Eugenia Garay-Sevilla, Humberto García-Ortiz, Christian Gieger, Benjamin Glaser, Clicerio González-Villalpando, Ma Elena Gonzalez, Niels Grarup, Leif Groop, Myron Gross, Christopher Haiman, Sohee Han, Craig L Hanis, Torben Hansen, Nancy L Heard-Costa, Brian E Henderson, Juan Manuel Malacara Hernandez, Mi Yeong Hwang, Sergio Islas-Andrade, Marit E Jørgensen, Hyun Min Kang, Bong-Jo Kim, Young Jin Kim, Heikki A Koistinen, Jaspal Singh Kooner, Johanna Kuusisto, Soo-Heon Kwak, Markku Laakso, Leslie Lange, Jong-Young Lee, Juyoung Lee, Donna M Lehman, Allan Linneberg, Jianjun Liu, Ruth J F Loos, Valeriya Lyssenko, Ronald C W Ma, Angélica Martínez-Hernández, James B Meigs, Thomas Meitinger, Elvia Mendoza-Caamal, Karen L Mohlke, Andrew D Morris, Alanna C Morrison, Maggie C Y Ng, Peter M Nilsson, Christopher J O'Donnell, Lorena Orozco, Colin N A Palmer, Kyong Soo Park, Wendy S Post, Oluf Pedersen, Michael Preuss, Bruce M Psaty, Alexander P Reiner, Cristina Revilla-Monsalve, Stephen S Rich, Jerome I Rotter, Danish Saleheen, Claudia Schurmann, Xueling Sim, Rob Sladek, Kerrin S Small, Wing Yee So, Timothy D Spector, Konstantin Strauch, Tim M Strom, E Shyong Tai, Claudia H T Tam, Yik Ying Teo, Farook Thameem, Brian Tomlinson, Russell P Tracy, Tiinamaija Tuomi, Jaakko Tuomilehto, Teresa Tusié-Luna, Rob M van Dam, Ramachandran S Vasan, James G Wilson, Daniel R Witte, Tien-Yin Wong, Noël P Burtt, Noah Zaitlen, Mark I McCarthy, Michael Boehnke, Toni I Pollin, Jason Flannick, Josep M Mercader, Anne O'Donnell-Luria, Samantha Baxter, Jose C Florez, Daniel G MacArthur, Miriam S Udler
Hundreds of thousands of genetic variants have been reported to cause severe monogenic diseases, but the probability that a variant carrier develops the disease (termed penetrance) is unknown for virtually all of them. Additionally, the clinical utility of common polygenetic variation remains uncertain. Using exome sequencing from 77,184 adult individuals (38,618 multi-ancestral individuals from a type 2 diabetes case-control study and 38,566 participants from the UK Biobank, for whom genotype array data were also available), we apply clinical standard-of-care gene variant curation for eight monogenic metabolic conditions...
June 9, 2021: Nature Communications
https://read.qxmd.com/read/33758387/neurodevelopmental-outcome-of-preterm-infants-enrolled-in-myo-inositol-randomized-controlled-trial
#14
JOURNAL ARTICLE
Ira Adams-Chapman, Kristi L Watterberg, Tracy L Nolen, Shawn Hirsch, Carol A Cole, C Michael Cotten, William Oh, Brenda B Poindexter, Kristin M Zaterka-Baxter, Abhik Das, Conra Backstrom Lacy, Ann Marie Scorsone, Andrea F Duncan, Sara B DeMauro, Ricki F Goldstein, Tarah T Colaizy, Deanne E Wilson-Costello, Isabell B Purdy, Susan R Hintz, Roy J Heyne, Gary J Myers, Janell Fuller, Stephanie Merhar, Heidi M Harmon, Myriam Peralta-Carcelen, Howard W Kilbride, Nathalie L Maitre, Betty R Vohr, Girija Natarajan, Helen Mintz-Hittner, Graham E Quinn, David K Wallace, Richard J Olson, Faruk H Orge, Irena Tsui, Michael Gaynon, Amy K Hutchinson, Yu-Guang He, Timothy W Winter, Michael B Yang, Kathryn M Haider, Martin S Cogen, Denise Hug, Don L Bremer, John P Donahue, William R Lucas, Dale L Phelps, Rosemary D Higgins
OBJECTIVE: This study evaluates the 24-month follow-up for the NICHD Neonatal Research Network (NRN) Inositol for Retinopathy Trial. STUDY DESIGN: Bayley Scales of Infants Development-III and a standardized neurosensory examination were performed in infants enrolled in the main trial. Moderate/severe NDI was defined as BSID-III Cognitive or Motor composite score <85, moderate or severe cerebral palsy, blindness, or hearing loss that prevents communication despite amplification were assessed...
March 23, 2021: Journal of Perinatology: Official Journal of the California Perinatal Association
https://read.qxmd.com/read/33595625/evaluating-growth-patterns-of-abdominal-aortic-aneurysm-diameter-with-serial-computed-tomography-surveillance
#15
JOURNAL ARTICLE
Sydney L Olson, Marniker A Wijesinha, Annalise M Panthofer, William C Blackwelder, Gilbert R Upchurch, Michael L Terrin, John A Curci, B Timothy Baxter, Jon S Matsumura
Importance: Small abdominal aortic aneurysms (AAAs) are common in the elderly population. Their growth rates and patterns, which drive clinical surveillance, are widely disputed. Objective: To assess the growth patterns and rates of AAAs as documented on serial computed tomography (CT) scans. Design, Setting, and Participants: Cohort study and secondary analysis of the Non-Invasive Treatment of Abdominal Aortic Aneurysm Clinical Trial (N-TA3CT), a randomized, double-blind placebo-controlled clinical trial conducted from 2013 to 2018, with CT imaging every 6 months for 2 years...
April 1, 2021: JAMA Surgery
https://read.qxmd.com/read/33079148/doxycycline-and-growth-of-abdominal-aortic-aneurysms-reply
#16
LETTER
B Timothy Baxter, John A Curci, Michael L Terrin
No abstract text is available yet for this article.
October 20, 2020: JAMA
https://read.qxmd.com/read/32616814/enhanced-notch3-signaling-contributes-to-pulmonary-emphysema-in-a-murine-model-of-marfan-syndrome
#17
JOURNAL ARTICLE
Kathryn Jespersen, Zhibo Liu, Chenxin Li, Paul Harding, Kylie Sestak, Rishi Batra, Christopher A Stephenson, Ryan T Foley, Harrison Greene, Trevor Meisinger, B Timothy Baxter, Wanfen Xiong
Marfan syndrome (MFS) is a heritable disorder of connective tissue, caused by mutations in the fibrillin-1 gene. Pulmonary functional abnormalities, such as emphysema and restrictive lung diseases, are frequently observed in patients with MFS. However, the pathogenesis and molecular mechanism of pulmonary involvement in MFS patients are underexplored. Notch signaling is essential for lung development and the airway epithelium regeneration and repair. Therefore, we investigated whether Notch3 signaling plays a role in pulmonary emphysema in MFS...
July 2, 2020: Scientific Reports
https://read.qxmd.com/read/32453369/effect-of-doxycycline-on-aneurysm-growth-among-patients-with-small-infrarenal-abdominal-aortic-aneurysms-a-randomized-clinical-trial
#18
RANDOMIZED CONTROLLED TRIAL
B Timothy Baxter, Jon Matsumura, John A Curci, Ruth McBride, LuAnn Larson, William Blackwelder, Diana Lam, Marniker Wijesinha, Michael Terrin
Importance: Abdominal aortic aneurysms affect more than 3% of US older adults. Objective: To test whether doxycycline reduces the growth of abdominal aortic aneurysm over 2 years as measured by maximum transverse diameter. Design, Setting, and Participants: Parallel, 2-group, randomized clinical trial that was conducted at 22 US clinical centers between May 2013 and January 2017, and enrolled patients 50 years or older with small (3.5-5.0 cm for men, 3...
May 26, 2020: JAMA
https://read.qxmd.com/read/31980239/ex-vivo-expansion-of-regulatory-t-cells-from-abdominal-aortic-aneurysm-patients-inhibits-aneurysm-in-humanized-murine-model
#19
JOURNAL ARTICLE
Melissa K Suh, Rishi Batra, Jeffrey S Carson, Wanfen Xiong, Matthew A Dale, Trevor Meisinger, Cameron Killen, John Mitchell, B Timothy Baxter
OBJECTIVE: Abdominal aortic aneurysm (AAA) is a chronic inflammatory disease. Studies of human aneurysm tissue demonstrate dense inflammatory cell infiltrates with CD4+ T cells predominating. Regulatory T cells (Tregs) play an important role in inhibiting pro-inflammatory T cell proliferation, therefore, limiting collateral tissue destruction. The aim of this study was to investigate whether ex vivo augmentation of human Tregs attenuates aneurysm formation in humanized murine model of AAA...
January 21, 2020: Journal of Vascular Surgery
https://read.qxmd.com/read/30885555/variability-in-perioperative-evaluation-and-resource-utilization-in-pediatric-patients-with-suspected-biliary-dyskinesia-a-multi-institutional-retrospective-cohort-study
#20
JOURNAL ARTICLE
Sarah B Cairo, Arturo Aranda, Marisa Bartz-Kurycki, Katherine J Baxter, Patrick Bonasso, Melvin Dassinger, Katherine J Deans, Danielle Dorey, Pamela Emengo, Elizabeth Fialkowski, Christopher Gayer, Brandy Gonzales, Nakada Gusman, Russell B Hawkins, Karen Herzing, Eunice Huang, Saleem Islam, Timothy Jancelewicz, Matthew P Landman, Kevin P Lally, Aaron Lesher, Peter C Minneci, Mehul V Raval, Robert Russell, Sohail Shah, Bethany Slater, Leah J Schoel, Shawn St Peter, Joseph Sujka, Jennifer Waterhouse, David H Rothstein
INTRODUCTION: Biliary dyskinesia (BD) is a common indication for pediatric cholecystectomy. While diagnosis is primarily based on diminished gallbladder ejection fraction (GB-EF), work-up and management in pediatrics is controversial. METHODS: We conducted a multi-institutional retrospective review of children undergoing cholecystectomy for BD to compare perioperative work-up and outcomes. RESULTS: Six hundred seventy-eight patients across 16 institutions were included...
March 2, 2019: Journal of Pediatric Surgery
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