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https://www.readbyqxmd.com/read/29759854/a-meta-analysis-of-reduced-leaflet-motion-for-surgical-and-transcatheter-aortic-valves-relationship-to-cerebrovascular-events-and-valve-degeneration
#1
Nader Makki, Satya Shreenivas, Dean Kereiakes, Scott Lilly
BACKGROUND: Reduced leaflet motion (RLM) of transcatheter aortic valves (TAV) is observed in up to 4% of cases with similar frequency in surgical valves, with an overall incidence that differs based on prosthesis type and size. This phenomenon likely represents subclinical leaflet thrombosis. Herein we sought to analyze the existing reported literature to assess whether or not RLM is associated with subsequent valve degeneration or cerebrovascular events. METHODS AND RESULTS: We searched PubMed, and EMBASE (2008-2017) to identify relevant studies...
April 5, 2018: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29755075/-huge-left-thrombosis-after-mitral-valvuloplasty-and-maze-procedure-report-of-a-case
#2
Hitomi Naruse, Noriyasu Kawada, Koichi Muramatsu, Hirokuni Naganuma, Kazuhiro Hashimoto
Generally, anticoagulation therapy is not essential for patients who maintain sinus rhythm after mitral valvuloplasty. A 66-year-old woman who had undergone mitral valvuloplasty and maze procedure for treatment of mitral valve regurgitation and atrial fibrillation 4 years ago was diagnosed as having left atrial thrombosis despite maintenance of sinus rhythm on electrocardiography. Echocardiography showed narrow mitral valvular area(1.5 cm2), loss of A wave and a huge left atrium. Repeat surgery was performed to replace the mitral valve and to remove the thrombus...
March 2018: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/29746313/avalonelite-double-lumen-cannula-for-total-cavopulmonary-assist-in-failing-fontan-sheep-model-with-valved-extracardiac-conduit
#3
Cheng Zhou, Dongfang Wang, Francesca Condemi, Guangfeng Zhao, Stephen Topaz, Cherry Ballard-Croft, Joseph B Zwischenberger
The AvalonElite double lumen cannula (DLC) provides total cavopulmonary assist (CPA) in failing Fontan sheep, but recirculation limits reliability. To improve CPA performance, a two-valve extracardiac conduit (ECC) was used to bracket infusion blood toward pulmonary artery (PA). A total cavopulmonary connection with failing Fontan circulation adult sheep model was created with valved ECC (n = 6). The valved ECC was connected to superior/inferior venae cavae (SVC/IVC) and right PA. The AvalonElite DLC was inserted from right jugular vein with infusion opening between the ECC valves...
May 8, 2018: ASAIO Journal: a Peer-reviewed Journal of the American Society for Artificial Internal Organs
https://www.readbyqxmd.com/read/29736556/-correct-positioning-of-central-venous-catheters-in-pediatrics-are-current-formulae-really-useful
#4
REVIEW
C Cleff, M Boensch, F Eifinger, J Hinkelbein
BACKGROUND: Correct positioning of a central venous catheter (CVC) tip in pediatric patients is very important. Malpositioning may lead to direct complications, such as arrhythmia and increase the risk of thrombosis, infections, valve failures or pericardial tamponade. OBJECTIVE: The aim of this review was to identify and summarize published formulae for the correct positioning of the CVC tip in children and to discuss the benefits of these formulae for the daily routine...
May 7, 2018: Der Anaesthesist
https://www.readbyqxmd.com/read/29726041/reoperation-for-composite-valve-graft-failure-operative-results-and-midterm-survival
#5
Luis C Maroto, Manuel Carnero, Javier Cobiella, Mónica García, Isidre Vilacosta, Fernando Reguillo, Enrique Villagrán, Carmen Olmos
BACKGROUND AND AIM OF THE STUDY: The replacement of a failed composite valve graft is technically more demanding and is associated with increased morbidity and mortality. We present our technique and outcomes for reoperations for composite graft failures. METHODS: Between September 2011 and June 2017, 14 patients underwent a redo composite graft replacement. Twelve patients (85.7%) were male, and mean age was 58.4 years ± 12 standard deviation (SD). One patient had two previous root replacements...
May 3, 2018: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/29701388/trifecta-bioprothesis-for-aortic-valve-replacement-our-experience
#6
João Pedro Monteiro, Diogo Rijo, Sara Simões Costa, Rodolfo Pereira, Ricardo Ferraz, Miguel Guerra
INTRODUCTION: Bioprosthesis are increasingly used for aortic valve replacement (AVR), as a result of increasing elderly patients, as well as, continuous improvements in durability and hemodynamic performance of pericardial prosthesis. The Trifecta aortic prosthesis is a latest-generation trileaflet stented pericardial valve designed for supra-annular placement in the aortic position. This study establishes the safety and early clinical and hemodynamic performance of the Trifecta valve...
July 2017: Revista Portuguesa de Cirurgia Cardio-torácica e Vascular
https://www.readbyqxmd.com/read/29701120/comparison-of-two-types-of-catheters-through-femoral-vein-catheterization-in-patients-with-lung-cancer-undergoing-chemotherapy-a-retrospective-study
#7
Binbin Xu, Jinghui Zhang, Siyuan Tang, Jianmei Hou, Mengdan Ma
PURPOSE: This study aimed to investigate the effects and complications of different types of peripherally inserted central catheters through femoral vein catheterization in patients with lung cancer undergoing chemotherapy. METHODS: A retrospective analysis of 158 patients with lung cancer undergoing implantation of a venous access through femoral vein catheterization was performed. The patients were divided into two groups by convenience sampling: the single-lumen silicone Groshong peripherally inserted central catheters with valved tip were used in patients in group A, the single-lumen power-injectable polyurethane peripherally inserted central catheters with no valve were used in patients in group B...
April 1, 2018: Journal of Vascular Access
https://www.readbyqxmd.com/read/29697545/transcatheter-valvular-interventions-in-2017-some-things-old-some-things-new
#8
Hasan Rehman, Neal S Kleiman, Ankur Kalra
PURPOSE OF REVIEW: Transcatheter valvular interventions have changed the landscape of valvular therapies. We examine some studies on transcatheter valvular interventions published in the year 2017 to better understand their implications on clinical practice and future research. RECENT FINDINGS: Findings from the SURTAVI study suggest TAVR to be a reasonable option in intermediate risk patients with aortic stenosis. Recent studies indicate that valve leaflet thrombosis is associated with poor outcomes...
April 24, 2018: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/29696409/valvular-heart-disease-and-pregnancy
#9
REVIEW
Emily S Lau, Nandita S Scott
With improving reproductive assistive technologies, advancing maternal age, and improved survival of patients with congenital heart disease, valvular heart disease has become an important cause of morbidity and mortality in pregnant women. In general, stenotic lesions, even those in the moderate range, are poorly tolerated in the face of hemodynamic changes of pregnancy. Regurgitant lesions, however, fare better due to the physiologic afterload reduction that occurs. Intervention on regurgitant valve preconception follows the same principles as a non-pregnant population...
April 26, 2018: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29695530/modeling-venous-thrombosis-in-vitro-more-than-just-valve-pocket-change
#10
EDITORIAL
Alisa S Wolberg
No abstract text is available yet for this article.
May 2018: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/29689593/transcatheter-technologies-for-valvular-replacement-an-update
#11
Antonio Nenna, Sanjeet Singh Avtaar Singh, Simone Morganti, Laura Mazzocchi, Ferdinando Auricchio, Massimo Chello, Francesco Nappi
This report provides a brief overview of the basic principles, recent advances, and recommendations for the treatment of severe aortic stenosis with transcatheter aortic valve replacement (TAVR) in adults. Approaches that avoid neurological, cardiac and peripheral vascular complications have been developed. In addition, TAVR can be performed in intermediate- and low-risk patients. However, these procedures require specialized training and may not allow for complete resolution of the underlying issue. Even if cardiologists learn to perform the procedure and despite advancements in device technology, TAVR is still susceptible to structural valve degeneration, thrombosis and late cerebral embolization...
April 23, 2018: Surgical Technology International
https://www.readbyqxmd.com/read/29667205/application-of-heparin-collagen-redv-selective-active-interface-on-eptfe-films-to-enhance-endothelialization-and-anticoagulation
#12
Yaping Shan, Bing Jia, Ming Ye, Hua Shen, Weicheng Chen, Huifeng Zhang
Expanded polytetrafluoroethylene (ePTFE) prosthetic valves have been widely used in clinical applications in Asian countries. However, these valves still have limits with regard to thrombosis, neointimal hyperplasia, restenosis, and valvar vegetation. The achievement of in situ endothelialization on implant materials is a promising way to overcome those limits. Here, heparin/collagen multilayers were fabricated on ePTFE films via a layer-by-layer (LBL) self-assembly technique, and then, the endothelial cell (EC) adhesive peptide sequence Arg-Glu-Asp-Val (REDV) was immobilized on the multilayers...
April 18, 2018: Artificial Organs
https://www.readbyqxmd.com/read/29666072/left-ventricular-assist-device-inflow-cannula-angle-and-thrombosis-risk
#13
Venkat Keshav Chivukula, Jennifer A Beckman, Anthony R Prisco, Todd Dardas, Shin Lin, Jason W Smith, Nahush A Mokadam, Alberto Aliseda, Claudius Mahr
BACKGROUND: As heart failure prevalence continues to increase in the setting of a static donor supply, left ventricular assist device (LVAD) therapy for end-stage heart failure continues to grow. Anecdotal evidence suggests that malalignment of the LVAD inflow cannula may increase thrombosis risk, but this effect has not been explored mechanistically or quantified statistically. Our objective is to elucidate the impact of surgical angulation of the inflow cannula on thrombogenicity. METHODS AND RESULTS: Unsteady computational fluid dynamics is used in conjunction with computational modeling and virtual surgery to model flow through the left ventricle for 5 different inflow cannula angulations...
April 2018: Circulation. Heart Failure
https://www.readbyqxmd.com/read/29649341/how-does-your-piccompare-a-pilot-randomized-controlled-trial-comparing-various-picc-materials-in-pediatrics
#14
Tricia Kleidon, Amanda J Ullman, Li Zhang, Gabor Mihala, Brett Chaseling, Jason Schoutrop, Claire M Rickard
BACKGROUND: Despite the popularity of peripherally inserted central catheters (PICCs), recent literature highlights their potential injurious complications. Innovative PICC materials have been developed to prevent thrombosis and infection formation (Endexo®) and antireflux valves to prevent occlusion (pressure-activated safety valve®). No large randomized controlled trial has assessed these technologies. Our primary aim was to evaluate the feasibility of a large randomized controlled efficacy trial of PICC materials and design to reduce PICC complication in pediatrics...
February 8, 2018: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/29644227/pathologic-confirmation-of-valve-thrombosis-detected-by-four-dimensional-computed-tomography-following-valve-in-valve-transcatheter-aortic-valve-replacement
#15
Ambarish Gopal, Nathalia Ribeiro, John J Squiers, Elizabeth M Holper, Michael Black, Deepika Gopal, Molly Szerlip, Katherine B Harrington, Srinivas Potluri, J Michael DiMaio, David L Brown, Paul A Grayburn, Michael J Mack, William T Brinkman
A major concern regarding transcatheter aortic valve replacement (TAVR) is leaflet thrombosis. Four-dimensional computed tomography (4D-CT) is the preferred imaging modality to evaluate patients with suspected valve thrombosis. To date, the abnormal findings visualized by 4D-CT suggestive of leaflet thrombosis have lacked pathologic confirmation from a surgically explanted valve in a surviving patient. Herein, we provide pathologic confirmation of thrombus formation following surgical explantation of a thrombosed TAVR prosthesis that was initially identified by 4D-CT...
June 30, 2017: Global Cardiology Science & Practice
https://www.readbyqxmd.com/read/29629921/assessment-of-cardiac-thrombosis-in-patients-with-left-ventricular-assist-device-using-multidetector-cardiac-computed-tomography
#16
Chukwuemeka A Obi, Nicholas Chan, Monica G Rizkalla, John N Makaryus
: A 79-year-old man with nonischemic cardiomyopathy who underwent left ventricular assist device HeartMate II and automated implantable cardioverter defibrillator placement presented with recurrent refractory sustained ventricular tachycardia, elevated lactate dehydrogenase, and low haptoglobin. Echocardiography demonstrated no thrombosis; cardiac computed tomography showed patent inflow and outflow cannulas while detecting an irregularly shaped mass adherent to the left coronary cusp of the aortic valve, suggesting a thrombus...
April 7, 2018: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/29623558/why-i-choose-to-repair-and-not-to-replace-the-aortic-valve
#17
Athanasios Antoniou, Amer Harky, Mohamad Bashir, Gebrine El Khoury
Aortic valve replacement whether surgical or transcutaneous remains an option for the treatment of severe aortic valve disease; however, current prosthetic devices are associated with complications including, but no limited to, valve thrombosis and thromboembolic events, bleeding events associated with anticoagulation use, prosthetic valve endocarditis and structural valve deterioration. In this effect, aortic valve repair (AVr) has become an attractive alternative in circumventing these potential complications by preservation of the native aortic valve apparatus...
April 5, 2018: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29618696/subclinical-leaflet-thrombosis-in-transcatheter-aortic-valve-replacement-detected-by-multidetector-computed-tomography-a-review-of-current-evidence
#18
Hashrul N Rashid, Adam J Brown, Liam M McCormick, Ameera S Amiruddin, Kim K Be, James D Cameron, Arthur Nasis, Robert P Gooley
Subclinical leaflet thrombosis (SLT) following transcatheter aortic valve replacement (TAVR) has been increasingly recognized. SLT has the hallmark features of hypo-attenuated leaflet thickening (HALT) on multidetector computed tomography (MDCT), which may result in hypoattenuation affecting motion (HAM). The actual prevalence of this condition is uncertain, with limited observational registries. SLT has caught the attention of the cardiovascular community because of concerns regarding its clinical sequelae, specifically the potential increased incidence of cerebrovascular events...
April 4, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29595637/high-mobility-group-box-1-was-associated-with-thrombosis-in-patients-with-atrial-fibrillation
#19
Qiwen Xu, Lin Bo, Jiaxin Hu, Jin Geng, Yuhan Chen, Xuelin Li, Fu Chen, Jie Song
INTRODUCTION: High mobility group box 1 (HMGB1) is a member of the HMGB family that is involved in inflammatory disease-related thrombosis. We hypothesize that HMGB1 and its downstream factors are associated with thrombosis in atrial fibrillation (AF). MATERIALS AND METHODS: Our experimental materials were the left atrial appendage (LAA) tissues from patients undergoing valve replacement. The samples were divided into 3 groups: a sinus rhythm group (n = 15), an AF(+)thrombus(-)group (n = 15), and an AF(+) thrombus (+)group (n = 15)...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29593835/assessing-the-risk-of-leaflet-motion-abnormality-following-transcatheter-aortic-valve-implantation
#20
Luca Testa, Azeem Latib
Leaflet motion abnormalities are a relatively new entity in the field of transcatheter aortic valve implantation and are associated with a range of different conditions, the extreme being prosthetic valve dysfunction with high gradients or central regurgitation and possibly early thrombotic degeneration. Another extreme condition is the incidental finding of leaflet thickening, but with normal transvalvular gradients. Transthoracic echocardiography is a useful screening tool for the detection of symptomatic thrombosis, but it has limited use in the detection of subclinical thrombosis and/or motion abnormalities alone...
January 2018: Interventional Cardiology
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