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https://www.readbyqxmd.com/read/29134238/a-comparison-of-anterograde-versus-retrograde-approaches-for-neonatal-balloon-aortic-valvuloplasty
#1
Namrita Mozumdar, Edmund Burke, Melissa Schweizer, Matthew J Gillespie, Yoav Dori, Hari K Narayan, Jonathan J Rome, Andrew C Glatz
In neonates requiring balloon aortic valvuloplasty, both anterograde and retrograde approaches are feasible. A recent comparison of these two approaches is lacking. A retrospective cohort study of neonates at a single center undergoing BAV from 9/00 to 7/14 was performed. Records were reviewed including pre- and post-intervention echocardiograms and catheterization data. Comparisons of acute efficacy and procedural safety were made based on type of approach utilized. Forty-two neonates underwent BAV. Eleven cases utilized exclusively an anterograde approach, while 31 included a retrograde approach (including 4 with both approaches used)...
November 13, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29127117/very-early-subclinical-valve-thrombosis-after-transcatheter-aortic-valve-replacement
#2
Natalia Berry, Neal Sawlani, Alice Kim, Tsuyoshi Kaneko, Pinak Shah, Marc Pelletier, Piotr Sobieszczyk
No abstract text is available yet for this article.
November 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29106831/-transcatheter-aortic-valve-thrombosis
#3
D Leguay, S Duval, M Leroux, A Monnier, Y Davienne, C Brasselet
GOALS: Transcatheter aortic valve or leaflets thrombosis are mainly misapprehended. It negatively impacts the long-term efficiency of such prosthesis. Moreover, its incidence is presumably higher than previously described. EPIDEMIOLOGY: Recently reported subclinical leaflet thrombosis, occurring between first to third months after implantation, is about 10to 15%. All prosthesis are concerned by potential thrombosis. DIAGNOSIS: Transcatheter aortic valve thrombosis is usually detected on the basis of increased transvalvular pressure gradients or symptoms at routine follow-up...
October 26, 2017: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/29100908/quality-of-life-in-children-participating-in-a-non-selective-inr-self-monitoring-vka-education-programme
#4
Pascal Amedro, Fanny Bajolle, Helena Bertet, Radhia Cheurfi, Dominique Lasne, Erika Nogue, Pascal Auquier, Marie-Christine Picot, Damien Bonnet
BACKGROUND: The quality of life (QoL) of children receiving vitamin K antagonist (VKA) treatment has been scarcely studied. AIM: To assess QoL of children, and its evolution, throughout our non-selective international normalized ratio (INR) self-monitoring education programme. METHODS: Children and parents completed QoL questionnaires (Qualin, PedsQL) during education sessions. Scores were compared with those from controls. RESULTS: A total of 111 children (mean±standard deviation age 8...
October 31, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/29096024/antithrombotic-therapy-in-atrial-fibrillation-associated-with-valvular-heart-disease-a-joint-consensus-document-from-the-european-heart-rhythm-association-ehra-and-european-society-of-cardiology-working-group-on-thrombosis-endorsed-by-the-esc-working-group
#5
Gregory Y H Lip, Jean Philippe Collet, Raffaele de Caterina, Laurent Fauchier, Deirdre A Lane, Torben B Larsen, Francisco Marin, Joao Morais, Calambur Narasimhan, Brian Olshansky, Luc Pierard, Tatjana Potpara, Nizal Sarrafzadegan, Karen Sliwa, Gonzalo Varela, Gemma Vilahur, Thomas Weiss, Giuseppe Boriani, Bianca Rocca
Atrial fibrillation (AF) is a major worldwide public health problem, and AF in association with valvular heart disease (VHD) is also common. However, management strategies for this group of patients have been less informed by randomized trials, which have largely focused on 'non-valvular AF' patients. Thrombo-embolic risk also varies according to valve lesion and may also be associated with CHA2DS2VASc score risk factor components, rather than only the valve disease being causal. Given marked heterogeneity in the definition of valvular and non-valvular AF and variable management strategies, including non-vitamin K antagonist oral anticoagulants (NOACs) in patients with VHD other than prosthetic heart valves or haemodynamically significant mitral valve disease, there is a need to provide expert recommendations for professionals participating in the care of patients presenting with AF and associated VHD...
November 1, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29092122/treatment-of-prosthetic-valve-thrombosis-with-bolus-dose-tenecteplase-an-experience-from-a-developing-country
#6
Rajesh Kumar Jha, Sandeep Bansal, H S Issar, Mayuresh Chaudhary, Sonu Sharma
BACKGROUND: Prosthetic valve thrombosis (PVT) in metallic prosthetic cardiac valves is not an uncommon condition, and has high mortality and morbidity. Although surgery is the traditional choice for PVT therapy, thrombolysis with newer agents has achieved good success rates. Many studies described in the western literature have used tissue plasminogen activators, while studies from developing countries have been largely based on the use of streptokinase and urokinase. Data regarding the use of newer agents such as tenecteplase are scant...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29092121/obstructive-thrombosis-of-left-sided-mechanical-heart-valves-clinical-profile-and-thrombolytic-therapy
#7
Arumugam Chandrakasu, Avinash Jayachandran, Pradeep Gopinath Nayar, Chokkalingam Meyyappan, Ganesh Narayan, Ahamed Basha Abdul Bari, Prince Johnson Samuel
BACKGROUND: Thrombosis of a mechanical prosthetic heart valve is a potentially life-threatening complication associated with a high mortality. Although thrombolytic therapy has been considered highly beneficial in this situation, very few studies have been conducted to monitor the effectiveness of such thrombolytic therapy among Asian populations. Hence, the study aim was to evaluate the clinical profile, efficacy and safety of the thrombolytic agent streptokinase (SK) in patients with obstructive thrombosis of a left-sided mechanical heart valve...
May 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29081172/-effect-of-transcatheter-aortic-valve-replacement-using-venus-a-valve-for-treating-patients-with-severe-aortic-stenosis
#8
G Y Song, M Y Wang, Y Wang, X B Liu, Y Feng, X Q Kong, Y J Wu
Objective: To evaluate the effect of transcatheter aortic valve replacement(TAVR) using Venus-A valve for treating patients with severe aortic stenosis. Methods: In this prospective study, 101 consecutive severe aortic stenosis patients with high surgical risk(Society of Thoracic Surgeon(STS) score ≥4%) or at prohibitive surgical risk were enrolled from 5 academic cardiovascular centers in China(Fuwai hospital, the second affiliated hospital of Zhejiang university school of medicine, West China hospital of Sichuan university, the first affiliated hospital of Nanjing medical university, Ruijin hospital of Shanghai Jiaotong university school of medicine) from September 2012 to January 2015, and Venus-A valves were used in TAVR for these patients...
October 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29068163/bioprosthetic-tricuspid-valve-thrombosis-percutaneous-pfo-closure-to-improve-hypoxia-and-respiratory-failure
#9
Peter Flueckiger, Matthew Singleton, Sujethra Vasu, David Zhao
Prosthetic valve thrombosis (PVT) is an increasingly recognized complication of bioprosthetic valve replacement, often resulting in abnormal hemodynamic, endothelial, and hemostatic conditions. Bioprosthetic PVT may lead to significant hemodynamic and clinical effects. In hemodynamically stable patients, first-line treatment for bioprosthetic PVT is systemic anticoagulation. However, concomitant cardiovascular pathology may lead to additional clinical sequalae that requires acute therapeutic interventions. We describe two cases in which bioprosthetic PVT leads to hemodynamically significant intracardiac shunting through pre-existing patent foramen ovales requiring percutaneous closure with a Cribriform AMPLATZER occluder device...
October 25, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29066342/bioprosthesis-leaflet-thrombosis-following-self-expanding-valve-in-valve-transcatheter-aortic-valve-replacement-in-patient-taking-factor-xa-inhibitor-and-warfarin-a-case-report
#10
Kyle D Buchanan, M Chadi Alraies, Gaby Weissman, Itsik Ben-Dor, Lowell F Satler, Ron Waksman
An 87-year-old female with symptomatic severe aortic stenosis underwent transcatheter valve replacement (TAVR) via the transfemoral approach with a 29mm self-expanding device. Moderate to severe paravalvular regurgitation led to the development of congestive heart failure and hospital readmission 1 month following TAVR. A second 29mm valve was placed to abolish the paravalvular regurgitation. Routine follow-up computed tomography (CT) imaging demonstrated leaflet thickening and decreased leaflet mobility suggesting valve thrombosis, despite adherence to Factor Xa inhibitor...
May 11, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29065242/ageing-of-the-venous-valves-as-a-new-risk-factor-for-venous-thrombosis-in-the-elderly-the-batavia-study
#11
A Karasu, A Šrámek, F R Rosendaal, R J van der Geest, A van Hylckama Vlieg
BACKGROUND: Increasing age is the strongest risk factor for venous thrombosis (VT). Increasing age has been related to a thickening of the venous valves and a decreased valvular function. The association between valve thickness and the risk of VT is not known. OBJECTIVES: To assess the association between increased valve thickness and valve closure time (VCT) and the risk of VT. METHODS: Analyses were performed in the BATAVIA study, including 70 cases aged 70+ with a first VT and 96 controls...
October 24, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/29062744/transcatheter-aortic-valve-replacement-in-intermediate-and-low-risk-patients-clinical-evidence
#12
Sameer Arora, John P Vavalle
The encouraging results of the PARTNER 2 (Placement of AoRtic TraNscathetER Valves 2) trial led to the approval of transcatheter aortic valve replacement (TAVR) in intermediate-surgical-risk patients. Recently, the SURTAVI (SUrgical Replacement and Transcatheter Aortic Valve Implantation) investigators demonstrated the feasibility of TAVR with self-expanding valves in intermediate-risk patients. The focus has now shifted to clinical trials comparing TAVR to surgery in low-surgical-risk populations with a goal to expand TAVR to all-risk patients...
September 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29062739/pros-and-cons-of-transcatheter-aortic-valve-implantation-tavi
#13
REVIEW
Juan A Terré, Isaac George, Craig R Smith
Transcatheter aortic valve implantation (TAVI) or replacement (TAVR) was recently approved by the FDA for intermediate risk patients with severe aortic stenosis (AS). This technique was already worldwide adopted for inoperable and high-risk patients. Improved device technology, imaging analysis and operator expertise has reduced the initial worrisome higher complications rate associated with TAVR, making it comparable to surgical aortic valve replacement (SAVR). However, many answers need to be addressed before adoption in lower risk patients...
September 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29061574/anatomy-and-flow-characteristics-of-neosinus-important-consideration-for-thrombosis-of-transcatheter-aortic-valves
#14
EDITORIAL
Samir Kapadia, E Murat Tuzcu, Lars G Svensson
No abstract text is available yet for this article.
October 24, 2017: Circulation
https://www.readbyqxmd.com/read/29055768/acute-obstructive-thrombosis-of-sapien%C3%A2-3%C3%A2-valve-after-valve-in-valve-transcatheter-aortic-valve-replacement-for-degenerated-mosaic-21-valve
#15
Caterina Gandolfo, Marco Turrisi, Fabrizio Follis, Francesco Clemenza, Calogero Falletta, Giovanni Gentile, Rosa Liotta, Giuseppe M Raffa, Michele Pilato
No abstract text is available yet for this article.
October 12, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29055629/early-prosthetic-valve-dysfunction-due%C3%A2-to%C3%A2-bioprosthetic-valve-thrombosis-the-role-of-echocardiography
#16
Alexander Egbe, Sorin V Pislaru, Mahmoud A Ali, Arooj R Khan, Amber N Boler, Hartzell V Schaff, Emmanuel Akintoye, Heidi M Connolly, Vuyisile T Nkomo, Patricia A Pellikka
OBJECTIVES: The purpose of this study was to review the institutional practice of surveillance transthoracic echocardiography (TTE) for diagnosing early prosthetic valve dysfunction (PVD). BACKGROUND: Bioprosthetic valve thrombosis (BPVT) is an important cause of PVD, and guidelines do not recommend routine TTE during the first 5 years after valve implantation. METHODS: The authors performed a retrospective case-control study of all suspected (imaging diagnosis) or confirmed (histopathological diagnosis) cases of BPVT from January 1997 through December 2016...
October 14, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29053434/alpha-gal-inactivated-heart-valve-bioprostheses-exhibit-an-anti-calcification-propensity-similar-to-knockout-tissues
#17
Filippo Naso, Ugo Stefanelli, Edward Buratto, Giovanna Lazzari, Andrea Perota, Cesare Galli, Alessandro Gandaglia
BACKGROUND: Glutaraldehyde (GLA) has been used to crosslink bioprosthetic heart valve (BHVs) tissues to enhance their stability, besides ensuring a satisfactory degree of immunological tolerance. Unfortunately, GLA fixation does not guarantee a complete tissue biocompatibility of BHVs in currently used devices. The interaction between preformed human anti-alpha-Gal antibody and alpha-Gal antigens promotes the calcification of GLA-treated alpha-Gal-positive tissue. Recently, an alarming correlation between the presence of the alpha-Gal epitope and a premature BHVs degeneracy was reported...
October 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/29045647/mechanical-aortic-valve-replacement-in-non-elderly-adults-meta-analysis-and-microsimulation
#18
Nelleke M Korteland, Jonathan R G Etnel, Bardia Arabkhani, M Mostafa Mokhles, Arezo Mohamad, Jolien W Roos-Hesselink, Ad J J C Bogers, Johanna J M Takkenberg
Aims: To support decision-making regarding prosthetic valve selection in non-elderly adults, we aim to provide a detailed overview of outcome after contemporary mechanical aortic valve replacement (AVR). Methods and results: A systematic review was conducted for papers reporting clinical outcome after AVR with bileaflet mechanical valves with a mean patient age ≥18 and ≤55 years, published between 1 January 1995 and 31 December 2015. Through meta-analysis outcomes were pooled and entered into a microsimulation model to calculate (event-free) life expectancy and lifetime event risk...
May 10, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29045310/risk-of-stroke-after-transcatheter-prosthetic-aortic-valve-implant-with-aortic-bioprosthesis-subclinical-thrombosis-and-possible-therapeutic-implications
#19
Giuseppe Di Pasquale, Gloria V Coutsoumbas, Silvia Zagnoni
: Many factors could increase the risk of stroke after transcatheter prosthetic aortic valve implant, mainly related to the procedure itself, or to the type of valvular prosthesis, or to the presence of atrial fibrillation. There is a wide variability in the antithrombotic treatment utilized in clinical practice, as far as the choice of drugs (anticoagulant, single or dual antiplatelet treatment), and its optimal duration. The most popular therapeutic strategy, also recommended by the Scientific Societies, is dual antiplatelet (aspirin and clopidogrel) for the first 3-6 months then switching to single antiplatelet (usually aspirin), limiting oral anticoagulant therapy only to those patients with other primary indication to the treatment...
October 16, 2017: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/29044386/valve-thrombosis-after-tavi
#20
Philipp Ruile, Franz-Josef Neumann
No abstract text is available yet for this article.
September 21, 2017: European Heart Journal
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