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vitamin d and infertility

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https://www.readbyqxmd.com/read/28500824/vitamin-d-and-aspects-of-female-fertility
#1
REVIEW
Nick Voulgaris, Labrini Papanastasiou, George Piaditis, Anna Angelousi, Gregory Kaltsas, George Mastorakos, Eva Kassi
The role of vitamin D in female reproduction has been intensively examined over the last few decades. A large body of evidence suggests that vitamin D might have beneficial effects on metabolic/hormonal parameters of PCOS and endometriosis, while it appears to be associated with IVF outcomes. However, due to the heterogeneity among observational and interventional studies, no cause-effect relationship has yet been established. The aim of this review is to analyze recent in vitro animal and human studies which examined the association of vitamin D with disease entities affecting female fertility potential...
January 2017: Hormones: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28466668/concordance-of-vitamin-d-peripheral-levels-in-infertile-couples-partners
#2
Alessio Paffoni, Stefania Ferrari, Alice Mangiarini, Stefania Noli, Alessandro Bulfoni, Paola Vigano, Fabio Parazzini, Edgardo Somigliana
A large number of evidence supports the role of vitamin D insufficiency in both women and men infertility. However, no studies have evaluated the rate of concordance of vitamin D status between the partners. This finding might open new scenarios in the interpretation of the available data linking vitamin D insufficiency and infertility. In the present cross-sectional study, 103 consecutive infertile couples were recruited between April and May 2014. Both partners concomitantly provided a serum sample for the assessment of 25-hydroxy-vitamin D [25-(OH)-D]...
May 3, 2017: Gynecological Endocrinology
https://www.readbyqxmd.com/read/28436761/androgen-and-estrogen-shifts-in-men-before-and-after-bariatric-surgery-and-links-to-vitamins-and-trace-elements
#3
Alberto Rosenblatt, Joel Faintuch, Ivan Cecconello
Androgens and estrogens play a key role regarding sexual life and reproduction. Along with hypotestosteronemia, obese men exhibit a 2-fold increase in estradiol concentration, adversely infl uencing these parameters. Estrogens and adipokines also infl uence bone metabolism, exerting a direct effect on vitamin D, calcium homeostasis and bone health. Bariatric procedures normalize some sex hormones, and may reverse several obesity-related conditions. Estrogens levels may remain elevated postoperatively, and despite its protective effect on the skeleton, bariatric patients are more prone to fractures when compared to the general population...
April 24, 2017: International Journal for Vitamin and Nutrition Research. Journal International de Vitaminologie et de Nutrition
https://www.readbyqxmd.com/read/28435337/treatment-strategies-for-the-female-athlete-triad-in-the-adolescent-athlete-current-perspectives
#4
REVIEW
Jill Thein-Nissenbaum, Erin Hammer
Since the passage of Title IX in 1972, female sports participation has dramatically increased. The benefits of physical activity, including decreased risk for heart disease and diabetes as well as improved body image and self-esteem, far outweigh the risks. However, a select population of adolescent and young adult females may experience symptoms related to the female athlete triad (Triad), which refers to the interrelatedness of energy availability, menstrual function, and bone mineral density (BMD). These conditions often manifest clinically as disordered eating behaviors, menstrual irregularity, and stress fractures; an individual may suffer from 1 or all of the Triad components simultaneously...
2017: Open Access Journal of Sports Medicine
https://www.readbyqxmd.com/read/28401798/most-frequently-reported-prescription-medications-and-supplements-in-couples-planning-pregnancy-the-life-study
#5
Kristin Palmsten, Katrina F Flores, Christina D Chambers, Lauren A Weiss, Rajeshwari Sundaram, Germaine M Buck Louis
OBJECTIVE: To identify frequently reported prescription medications and supplements among couples planning pregnancy because there is a lack of descriptive information on these agents in women and men who are trying to conceive. METHODS: Five hundred one couples enrolled in the Longitudinal Study of Infertility and the Environment, which took place between 2005 and 2009. Participants reported prescription medications as well as prescription and over-the-counter supplements used through interviews at study enrollment and through daily dairies during the 12-month follow-up...
January 1, 2017: Reproductive Sciences
https://www.readbyqxmd.com/read/28333357/dietary-patterns-foods-and-nutrients-in-male-fertility-parameters-and-fecundability-a-systematic-review-of-observational-studies
#6
Albert Salas-Huetos, Mònica Bulló, Jordi Salas-Salvadó
BACKGROUND: Infertility is a global public health issue, affecting 15% of all couples of reproductive age. Male factors, including decreased semen quality, are responsible for ~25% of these cases. The dietary pattern, the components of the diet and nutrients have been studied as possible determinants of sperm function and/or fertility. OBJECTIVE AND RATIONALE: Previous systematic reviews have been made of the few heterogeneous low-quality randomized clinical trials (RCTs) conducted in small samples of participants and investigating the effect of specific nutrients and nutritional supplements on male infertility...
March 10, 2017: Human Reproduction Update
https://www.readbyqxmd.com/read/28326519/influence-of-diet-on-the-risk-of-developing-endometriosis
#7
Joanna Jurkiewicz-Przondziono, Magdalena Lemm, Anna Kwiatkowska-Pamuła, Ewa Ziółko, Mariusz K Wójtowicz
Endometriosis is a hormone-dependent chronic inflammatory disease characterized by the presence of endometrium beyond the uterine cavity. The disease affects 5-15% of women of child-bearing age, 30-50% of whom suffer from infertility. Understanding the role of dietary factors in the development of endometriosis is critical to development of effective dietary instructions for prevention. Existing studies concerning nutrition and endometriosis suggest that diet is a potentially modifiable risk factor for endometriosis...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28131909/differential-gene-expression-by-1-25-oh-2d3-in-an-endometriosis-stromal-cell-line
#8
Sue Ann Ingles, Liang Wu, Benjamin T Liu, Yibu Chen, Chun-Yeh Wang, Claire Templeman, Doerthe Brueggmann
Endometriosis is a common female reproductive disease characterized by invasion of endometrial cells into other organs, frequently causing pelvic pain and infertility. Alterations of the vitamin D system have been linked to endometriosis incidence and severity. To shed light on the potential mechanism for these associations, we examined the effects of 1,25(OH)2D3 on gene expression in endometriosis cells. Stromal cell lines derived from endometriosis tissue were treated with 1,25(OH)2D3, and RNA-seq was used to identify genes differentially expressed between treated and untreated cells...
January 28, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28119950/optimizing-inflammatory-bowel-disease-for-successful-in-vitro-fertilization
#9
Jason J Pan, Mora Cannon, Edward Kane, Gauree Konijeti
We present a nulliparous woman with mild to moderate ulcerative colitis (UC) and multiple failed cycles of in vitro fertilization (IVF) in whom we achieved a successful, viable pregnancy following clinical and endoscopic UC remission. Infertile patients with inflammatory bowel disease who have failed multiple cycles of IVF should try to achieve clinical remission and mucosal healing (absence of erosions or ulcers) prior to reattempting conception. Furthermore, deficiencies in vitamin B12, vitamin D, and iron should be addressed...
August 2016: ACG Case Reports Journal
https://www.readbyqxmd.com/read/28102491/shedding-new-light-on-female-fertility-the-role-of-vitamin-d
#10
REVIEW
Giovanna Muscogiuri, Barbara Altieri, Cristina de Angelis, Stefano Palomba, Rosario Pivonello, Annamaria Colao, Francesco Orio
In the last decades several studies suggested that vitamin D is involved in the modulation of the reproductive process in women due to the expression of VDR and 1α-hydroxylase in reproductive tissues such as ovary, uterus, placenta, pituitary and hypothalamus. Vitamin D has also a role in the regulation of sex hormone steroidogenesis. Increasing evidence suggests that vitamin D might have a regulatory role in polycystic ovary syndrome (PCOS)-associated symptoms, including ovulatory dysfunction, insulin resistance and hyperandrogenism...
January 19, 2017: Reviews in Endocrine & Metabolic Disorders
https://www.readbyqxmd.com/read/28090459/anti-m%C3%A3-llerian-hormone-as-a-predictor-of-polycystic-ovary-syndrome-treated-with-clomiphene-citrate
#11
Andon Hestiantoro, Yuwono Sri Negoro, Yohana Afrita, Budi Wiweko, Kanadi Sumapradja, Muharam Natadisastra
OBJECTIVE: This study aimed to determine the threshold of anti-Müllerian hormone (AMH) as predictor of follicular growth failure in polycystic ovary syndrome (PCOS) patients treated with clomiphene citrate (CC). METHODS: Fifty female subjects with PCOS were recruited and divided into two groups based on successful and unsuccessful follicular growth. Related variables such as age, infertility duration, cigarette smoking, use of Moslem hijab, sunlight exposure, fiber intake, body mass index, waist circumference, AMH level, 25-hydroxy vitamin D level, and growth of dominant follicles were obtained, assessed, and statistically analyzed...
December 2016: Clinical and Experimental Reproductive Medicine
https://www.readbyqxmd.com/read/28030942/the-role-of-vitamin-d-in-reproductive-dysfunction-in-women-a-systematic-review
#12
REVIEW
Patrycja Skowrońska, Ewa Pastuszek, Waldemar Kuczyński, Mariusz Jaszczoł, Paweł Kuć, Grzegorz Jakiel, Izabela Wocławek-Potocka, Krzysztof Łukaszuk
Vitamin D is essential for the proper functioning of the human body. There is also evidence of its strong association with fertility problems in women. This review aims to evaluate the relationship between vitamin D and diseases affecting women's fertility (polycystic ovarian syndrome (PCOS), uterine leiomyomas and endometriosis), and in vitro fertilization (IVF) outcome. A systematic review of the literature was conducted in Scopus and PubMed for relevant English language publications since 1989. Vitamin D influences the functioning of the reproductive system in women and has been associated with PCOS, uterine leiomyomas, endometriosis and in vitro fertilization (IVF) outcome...
December 23, 2016: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/27977320/selection-of-high-quality-spermatozoa-may-be-promoted-by-activated-vitamin-d-in-the-woman
#13
Lasse Bøllehuus Hansen, Anders Rehfeld, Rosanna de Neergaard, John Erik Nielsen, Lea Hedegaard Iversen, Ida Marie Boisen, Li Juel Mortensen, Beate Lanske, Kristian Almstrup, Elisabeth Carlsen, Anders Hayden Berg, Niels Jørgensen, Anders Nyboe Andersen, Anders Juul, Martin Blomberg Jensen
Context: The vitamin D receptor (VDR) and enzymes involved in activation (CYP2R1, CYP27B1) and inactivation (CYP24A1) of vitamin D are expressed in ovary, testes, and spermatozoa. Objective: Determine responsiveness to 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] in spermatozoa from normal and infertile men, and identify the site of exposure and how 1,25(OH)2D3 influences sperm function. Design: Spermatozoa expressing VDR, CYP2R1, CYP27B1, and CYP24A1 were analyzed in normal and infertile men...
March 1, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27927849/the-effect-of-serum-vitamin-d-levels-on-ovarian-reserve-markers-a-prospective-cross-sectional-study
#14
Panagiotis Drakopoulos, Arne van de Vijver, Valerie Schutyser, Stevan Milatovic, Ellen Anckaert, Johan Schiettecatte, Christophe Blockeel, Michel Camus, Herman Tournaye, Nikolaos P Polyzos
STUDY QUESTION: Is there any association between serum 25-OH vitamin D levels and ovarian reserve markers in infertile women? SUMMARY ANSWER: Vitamin D is not associated with the ovarian reserve markers, anti-mullerian hormone (AMH) and antral follicle count (AFC), in infertile women. WHAT IS KNOWN ALREADY: The mechanism underlying the relationship between vitamin D deficiency and reproduction is still unclear; however, evidence indicates a potential direct negative impact on ovarian function...
January 2017: Human Reproduction
https://www.readbyqxmd.com/read/27795706/inositol-treatment-and-art-outcomes-in-women-with-pcos
#15
REVIEW
Deepika Garg, Reshef Tal
Polycystic ovary syndrome (PCOS) affects 5-10% of women in reproductive age and is characterized by oligo/amenorrhea, androgen excess, insulin resistance, and typical polycystic ovarian morphology. It is the most common cause of infertility secondary to ovulatory dysfunction. The underlying etiology is still unknown but is believed to be multifactorial. Insulin-sensitizing compounds such as inositol, a B-complex vitamin, and its stereoisomers (myo-inositol and D-chiro-inositol) have been studied as an effective treatment of PCOS...
2016: International Journal of Endocrinology
https://www.readbyqxmd.com/read/27792863/association-of-vitamin-d-status-with-semen-quality-and-reproductive-hormones-in-iranian-subfertile-men
#16
Sh Abbasihormozi, A Kouhkan, A R Alizadeh, A H Shahverdi, M H Nasr-Esfahani, M A Sadighi Gilani, R Salman Yazdi, A Matinibehzad, Z Zolfaghari
Although vitamin D deficiency is one of the most common health problems throughout the world, including Iran, conflicting information exists on the potential association between serum vitamin D levels and semen quality. This study intended to evaluate the association between serum vitamin D [25(OH) D3] with semen quality and hormones in Iranian subfertile men. We also compared mean vitamin D and hormone levels in normospermic men with oligoasthenoteratozoospermia (OAT) men. This cross-sectional study was conducted on 278 men who were referred to Royan Infertility Clinic (Tehran, Iran) from March to September 2014...
January 2017: Andrology
https://www.readbyqxmd.com/read/27737331/highly-prevalence-of-vitamin-d-deficiency-among-brazilian-women-of-reproductive-age
#17
Vinicius Medina Lopes, Joaquim Roberto Costa Lopes, Jean Pierre Barguil Brasileiro, Ingrid de Oliveira, Ricardo Peclat Lacerda, Marcos Renato Dib Andrade, Natália Ivet Zavattiero Tierno, Roberto Costa Cavalcante de Souza, Luiz Augusto Casulari Roxo da Motta
Objective: Vitamin D has several metabolic functions and possible reproductive functions. This study aimed to determine the prevalence of vitamin D deficiency among Brazilian women of reproductive age, and to evaluate the relationship between serum 25-hydroxyvitamin D [25(OH)D] concentrations and infertility causes. Subjects and methods: This retrospective cross-sectional study evaluated data from a private Brazilian assisted reproduction center that were collected between January 1 and May 5, 2012...
January 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27693423/possible-influence-of-vitamin-d-on-male-reproduction
#18
Ida Marie Boisen, Lasse Bøllehuus Hansen, Li Juel Mortensen, Beate Lanske, Anders Juul, Martin Blomberg Jensen
Vitamin D is a versatile signaling molecule with an established role in the regulation of calcium homeostasis and bone health. In recent years the spectrum of vitamin D target organs has expanded and a reproductive role is supported by the presence of the vitamin D receptor (VDR) and the vitamin D metabolizing enzymes in the gonads, reproductive tract, and human spermatozoa. Interestingly, expression levels of VDR and the vitamin D inactivating enzyme CYP24A1 in human spermatozoa serve as positive predictive markers of semen quality and are higher expressed in spermatozoa from normal than infertile men...
September 28, 2016: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/27584605/body-weight-and-25-hidroxyvitamin-d-follicular-levels-a-prospective-study-of-women-submitted-to-in-vitro-fertilization
#19
Vitor As Deriquehem, Roberto A Antunes, Mila W Reginatto, Ana C Mancebo, Patricia Areas, Enrrico Bloise, Maria do Carmo B de Souza, Tania M Ortiga-Carvalho
OBJECTIVE: Vitamin D deficiency has been largely related to infertility in animals. However, data demonstrating a direct association between hypovitaminosis D and infertility in humans are still conflicting. Increased body weight and an elevated body mass index (BMI) are known for their association with infertility. Therefore, this study attempted to verify whether increases in body weight and the BMI were associated with lower 25-hidroxyvitamin D [25(OH)D3] levels in the follicular fluid (FF) of patients treated for infertility with intracytoplasmic sperm injections (ICSI)...
August 1, 2016: JBRA Assisted Reproduction
https://www.readbyqxmd.com/read/27496946/vitamin-d-deficiency-and-low-ionized-calcium-are-linked-with-semen-quality-and-sex-steroid-levels-in-infertile-men
#20
Martin Blomberg Jensen, Jacob Gerner Lawaetz, Anna-Maria Andersson, Jørgen Holm Petersen, Loa Nordkap, Anne Kirstine Bang, Pia Ekbom, Ulla Nordström Joensen, Lisbeth Prætorius, Peter Lundstrøm, Vibeke Hartvig Boujida, Beate Lanske, Anders Juul, Niels Jørgensen
STUDY QUESTION: Are low vitamin D levels linked with semen quality and sex steroids in infertile men? SUMMARY ANSWER: Infertile men with vitamin D deficiency had lower sperm motility, total numbers of motile sperm, Inhibin B, sex-hormone-binding-globulin (SHBG) and testosterone/estradiol ratio, but higher levels of free sex steroids, than infertile men with normal vitamin D levels. WHAT IS KNOWN ALREADY: Low vitamin D levels have been associated with decreased sperm motility in healthy men, but a relationship between vitamin D and calcium with semen quality and especially sex steroids has not been sufficiently described in infertile men...
August 2016: Human Reproduction
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