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affective touch

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https://www.readbyqxmd.com/read/28641990/do-negative-emotions-expressed-during-follow-up-consultations-with-adolescent-survivors-of-childhood-cancer-reflect-late-effects
#1
Anneli V Mellblom, Ellen Ruud, Jon Håvard Loge, Hanne C Lie
OBJECTIVE: To explore whether negative emotions expressed by adolescent cancer survivors during follow-up consultations were associated with potential late effects (persisting disease or treatment-related health problems). METHODS: We video-recorded 66 follow-up consultations between 10 pediatricians and 66 adolescent survivors of leukemia, lymphoma or stem-cell transplantations. In transcripts of the recordings, we identified utterances coded as both 1) expressions of negative emotions (VR-CoDES), and 2) late effect-related discussions...
June 14, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28632108/swallowing-in-parkinson-s-disease-clinical-issues-and-management
#2
Nick Miller
Changes to swallowing affect most people with Parkinson's disease (PD). Changes may not initially exercise a decisive impact, but can later pose significant threats to nutritional, hydration and respiratory health and psychosocial quality of life. This review, from a largely clinical viewpoint, outlines the nature of changes in PD and considers the issue of how many people are affected and in what ways. It outlines main approaches to assessment and management, with an emphasis on aspects relevant to PD. Dysphagia contributes to drooling in PD...
June 20, 2017: Neurodegenerative Disease Management
https://www.readbyqxmd.com/read/28630661/intrainsular-connectivity-and-somatosensory-responsiveness-in-young-children-with-asd
#3
Michelle D Failla, Brittany R Peters, Haleh Karbasforoushan, Jennifer H Foss-Feig, Kimberly B Schauder, Brynna H Heflin, Carissa J Cascio
BACKGROUND: The human somatosensory system comprises dissociable paths for discriminative and affective touch, reflected in separate peripheral afferent populations and distinct cortical targets. Differences in behavioral and neural responses to affective touch may have an important developmental role in early social experiences, which are relevant for autism spectrum disorder (ASD). METHODS: Using probabilistic tractography, we compared the structural integrity of white matter pathways for discriminative and affective touch in young children with ASD and their typically developing (TD) peers...
2017: Molecular Autism
https://www.readbyqxmd.com/read/28623280/ev-3-an-endogenous-human-erythropoietin-isoform-with-distinct-functional-relevance
#4
Christel Bonnas, Liane Wüstefeld, Daniela Winkler, Romy Kronstein-Wiedemann, Ekrem Dere, Katja Specht, Melanie Boxberg, Torsten Tonn, Hannelore Ehrenreich, Herbert Stadler, Inge Sillaber
Generation of multiple mRNAs by alternative splicing is well known in the group of cytokines and has recently been reported for the human erythropoietin (EPO) gene. Here, we focus on the alternatively spliced EPO transcript characterized by deletion of exon 3 (hEPOΔ3). We show co-regulation of EPO and hEPOΔ3 in human diseased tissue. The expression of hEPOΔ3 in various human samples was low under normal conditions, and distinctly increased in pathological states. Concomitant up-regulation of hEPOΔ3 and EPO in response to hypoxic conditions was also observed in HepG2 cell cultures...
June 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28619286/neuroprotective-potential-of-aloe-arborescens-against-copper-induced-neurobehavioral-features-of-parkinson-s-disease-in-rat
#5
Abdellatif Abbaoui, Omar El Hiba, Halima Gamrani
Copper (Cu) is an important trace element for the organism survival, which ensures the normal functioning of different biosystems. However, excessive levels of this heavy metal are responsible for profound physiological alterations including the central nervous system. Numerous findings sustain the involvement of heavy metals, as an environmental risk factor such as copper (Cu), in the neuropathology of Parkinson's disease (PD) which is a chronic neurodegenerative disorder that principally affects the motor system...
June 12, 2017: Acta Histochemica
https://www.readbyqxmd.com/read/28610830/mutual-regulation-between-infant-facial-affect-and-maternal-touch-in-depressed-and-nondepressed-dyads
#6
Ida Egmose, Katharina Cordes, Johanne Smith-Nielsen, Mette Skovgaard Væver, Simo Køppe
The ability to regulate affect is important for later adaptive child development. In the first months of life, infants have limited resources for regulating their own affects (e.g. by gaze aversion), and for this reason they are dependent on external affect regulation from their parents. Previous research suggests that touch is an important means through which parents regulate their infants' affects. Also, previous research has shown that post-partum depressed (PPD) mothers and nonclinical mothers differ in their touching behaviors when interacting with their infants...
June 10, 2017: Infant Behavior & Development
https://www.readbyqxmd.com/read/28609626/water-droplet-spreading-and-wicking-on-nanostructured-surfaces
#7
Xue Chen, Jian-Nan Chen, Xiaolong Ouyang, Yu Song, Ruina Xu, Pei-Xue Jiang
Phase-change heat transfer on nanostructured surfaces is an efficient cooling method for high heat flux devices due to its superior wettability. Liquid droplet spreading and wicking effect then dominate the heat transfer. Therefore, this study investigates the flow behavior after a droplet touches a nanostructured surface focusing on the ZnO nanowire surface with three different nanowire sizes and two array types (regular and irregular). The spreading diameter and the wicking diameter are measured against time...
June 13, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28608687/upconverting-nanoparticles-as-optical-sensors-of-nano-to-micro-newton-forces
#8
Alice Lay, Derek S Wang, Michael D Wisser, Randy D Mehlenbacher, Yu Lin, Miriam B Goodman, Wendy L Mao, Jennifer A Dionne
Mechanical forces affect a myriad of processes, from bone growth to material fracture to touch-responsive robotics. While nano- to micro-Newton forces are prevalent at the microscopic scale, few methods have the nanoscopic size and signal stability to measure them in vivo or in situ. Here, we develop an optical force-sensing platform based on sub-25 nm NaYF4 nanoparticles (NPs) doped with Yb(3+), Er(3+), and Mn(2+). The lanthanides Yb(3+) and Er(3+) enable both photoluminescence and upconversion, while the energetically coupled d-metal Mn(2+) adds force tunability through its crystal field sensitivity...
June 13, 2017: Nano Letters
https://www.readbyqxmd.com/read/28607672/prevalence-and-associated-risk-factors-of-violence-against-conflict-affected-female-adolescents-a-multi-country-cross-sectional-study
#9
Lindsay Stark, Khudejha Asghar, Gary Yu, Caroline Bora, Asham Assazenew Baysa, Kathryn L Falb
BACKGROUND: Over half of displaced civilians in humanitarian emergencies are children, and these settings pose unique threats to children's safety with long-lasting consequences. Our study broadens the limited evidence on violence against adolescent girls in emergencies by estimating prevalence and predictors of violence among adolescent girls aged 13-14 in South Kivu, Democratic Republic of the Congo (DRC), and aged 13-19 in refugee camps in the Benishangul-Gumuz region of Ethiopia. METHODS: Survey data were collected from a sample of 1296 adolescent girls using Computer-Assisted Personal Interview and Audio Computer-Assisted Self-Interview programming...
June 2017: Journal of Global Health
https://www.readbyqxmd.com/read/28599119/dendrites-enable-a-robust-mechanism-for-neuronal-stimulus-selectivity
#10
Romain D Cazé, Sarah Jarvis, Amanda J Foust, Simon R Schultz
Hearing, vision, touch: underlying all of these senses is stimulus selectivity, a robust information processing operation in which cortical neurons respond more to some stimuli than to others. Previous models assume that these neurons receive the highest weighted input from an ensemble encoding the preferred stimulus, but dendrites enable other possibilities. Nonlinear dendritic processing can produce stimulus selectivity based on the spatial distribution of synapses, even if the total preferred stimulus weight does not exceed that of nonpreferred stimuli...
June 9, 2017: Neural Computation
https://www.readbyqxmd.com/read/28597994/corneal-sensitivity-and-tear-production-in-108-horses-with-ocular-disease
#11
Kelly E Knickelbein, Nicole M Scherrer, Mary Lassaline
PURPOSE: To compare corneal sensitivity and tear production in horses with keratitis to horses with other ocular disease. METHOD: Retrospective medical record review was used to identify equine patients presented during a 1-year period for an ocular complaint who had Schirmer Tear Test (STT) or Corneal Touch Threshold (CTT) measured. Variables studied included patient age and sex; affected eye; category of presenting ocular complaint (keratitis vs. other ocular complaint); STT; and CTT...
June 9, 2017: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/28596902/the-effect-of-gender-norms-on-the-association-between-violence-and-hope-among-girls-in-the-democratic-republic-of-the-congo
#12
L Stark, K Asghar, S Meyer, G Yu, T Bakemore, C Poulton, K Falb
BACKGROUND: Girls at early stages of adolescence are vulnerable to violence victimization in humanitarian contexts, but few studies examine factors that affect girls' hope in these settings. We assessed attitudes toward traditional gender norms as an effect modifier of the relationship between violence exposure and future orientation in displaced girls. METHODS: Secondary analysis, using multivariable regression of cross-sectional data from girls ages 10-14 in South Kivu, Democratic Republic of the Congo...
2017: Global Mental Health
https://www.readbyqxmd.com/read/28589012/-they-will-be-afraid-to-touch-you-lgbti-people-and-sex-workers-experiences-of-accessing-healthcare-in-zimbabwe-an-in-depth-qualitative-study
#13
Jennifer Hunt, Katherine Bristowe, Sybille Chidyamatare, Richard Harding
OBJECTIVES: To examine experiences of key populations (lesbian, gay, bisexual, trans and intersex (LGBTI) people, men who have sex with men (MSM) and sex workers) in Zimbabwe regarding access to, and experiences of, healthcare. DESIGN: Qualitative study using in-depth interviews and focus groups, with thematic analysis. PARTICIPANTS: Sixty individuals from key populations in Zimbabwe. SETTING: Participants were recruited from four locations (Harare, Bulawayo, Mutare, Beitbridge/Masvingo)...
March 2017: BMJ Global Health
https://www.readbyqxmd.com/read/28576774/aff-1-fusogen-can-rejuvenate-the-regenerative-potential-of-adult-dendritic-trees-via-self-fusion
#14
Veronika Kravtsov, Meital Oren-Suissa, Benjamin Podbilewicz
The aging brain undergoes structural changes, affecting brain homeostasis, neuronal function and consequently cognition. The complex architecture of dendritic arbors poses a challenge to understanding age-dependent morphological alterations, behavioral plasticity and remodeling following brain injury. Here, we use the PVD polymodal neurons of C. elegans as a model to study how aging affects neuronal plasticity. Using confocal live imaging of C. elegans PVD neurons, we demonstrate age-related progressive morphological alterations of intricate dendritic arbors...
June 2, 2017: Development
https://www.readbyqxmd.com/read/28566678/the-relation-between-human-hair-follicle-density-and-touch-perception
#15
Emma H Jönsson, Johanna Bendas, Kerstin Weidner, Johan Wessberg, Håkan Olausson, Helena Backlund Wasling, Ilona Croy
Unmyelinated low threshold C-tactile fibers moderate pleasant aspects of touch. These fibers respond optimally to stroking stimulation of the skin with slow velocities (1-10 cm/s). Low threshold mechanoreceptors are arranged around hair follicles in rodent skin. If valid also in humans, hair follicle density (HFD) may relate to the perceived pleasantness of stroking tactile stimulation. We conducted two studies that examined the relation between HFD and affective touch perception in humans. In total, 138 healthy volunteers were stroked on the forearm and rated the pleasantness and intensity...
May 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28565998/gabab-receptors-mediated-tonic-inhibition-of-glutamate-release-from-a%C3%AE-fibers-in-rat-laminae-iii-iv-of-the-spinal-cord-dorsal-horn
#16
Chiara Salio, Adalberto Merighi, Rita Bardoni
Presynaptic GABAB receptors (GABABRs) are highly expressed in dorsal root ganglion neurons and spinal cord dorsal horn. GABABRs located in superficial dorsal horn play an important antinociceptive role, by acting at both pre- and postsynaptic sites. GABABRs expressed in deep dorsal horn could be involved in the processing of touch sensation and possibly in the generation of tactile allodynia in chronic pain. The objective of this study was to characterize the morphological and functional properties of GABABRs expressed on Aβ fibers projecting to lamina III/IV and to understand their role in modulating excitatory synaptic transmission...
January 2017: Molecular Pain
https://www.readbyqxmd.com/read/28560494/spatial-limits-of-visuotactile-interactions-in-the-presence-and-absence-of-tactile-stimulation
#17
Laura Mirams, Ellen Poliakoff, Donna M Lloyd
The presence of a light flash near to the body not only increases the ability to detect a weak touch but also increases reports of feeling a weak touch that did not occur. The somatic signal detection task (SSDT) provides a behavioural marker by which to clarify the spatial extent of such visuotactile interactions in peripersonal space. Whilst previous evidence suggests a limit to the spatial extent over which visual input can distort the perception of tactile stimulation during the rubber hand illusion, the spatial boundaries of light-induced tactile sensations are not known...
May 30, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28552388/characteristics-of-brief-sticky-mittens-training-that-lead-to-increases-in-object-exploration
#18
Amy Work Needham, Sarah E Wiesen, Jennifer N Hejazi, Klaus Libertus, Caroline Christopher
The onset of independent prehension marks the beginning of infants' direct interaction with the physical world. The success infants have in contacting objects with their hands and arms can have both visual and auditory consequences; objects may move and collide with other objects or fall onto table surfaces. Seeing and hearing these events could have important consequences for infants' learning about objects and their subsequent behavior toward objects. The current research assessed the effects of brief object manipulation experiences and how a specific characteristic of training, auditory feedback produced by hard plastic toys colliding with a tabletop surface, affects pre-reaching infants' subsequent object exploration...
May 25, 2017: Journal of Experimental Child Psychology
https://www.readbyqxmd.com/read/28544429/diabetes-and-cardiometabolic-risk-factors-in-cambodia-results-from-two-screening-studies
#19
Julie Wagner, Diana Naranjo, Touch Khun, Serey Seng, Ien Srey Horn, Sakinah Carter Suttiratana, Lim Keuky
BACKGROUND: Despite growing attention to diabetes throughout Asia, data from Southeast Asia are limited. This article reports rates of diabetes, hypertension and obesity in Cambodia. METHODS: Two studies were conducted across different regions of Cambodia: a 2012 screening study across urban, semi-urban and rural areas that used point of care capillary glucose for determination of diabetes (n = 13,997) and a 2005 epidemiological study with random selection from two main urban areas that used oral glucose tolerance tests for determination of diabetes (n = 1,863)...
May 22, 2017: Journal of Diabetes
https://www.readbyqxmd.com/read/28539934/stigma-sensitivity-and-the-duration-of-temporary-closure-are-affected-by-pollinator-identity-in-mazus-miquelii-phrymaceae-a-species-with-bilobed-stigma
#20
Xiao-Fang Jin, Zhong-Ming Ye, Grace M Amboka, Qing-Feng Wang, Chun-Feng Yang
A sensitive bilobed stigma is thought to assure reproduction, avoid selfing and promote outcrossing. In addition, it may also play a role in pollinator selection since only pollinators with the appropriate body size can trigger this mechanism. However, no experimental study has investigated how the sensitive stigma responds to different pollinators and its potential effects on pollination. Mazus miquelii (Phrymaceae), a plant with a bilobed stigma was studied to investigate the relationship between stigma behaviors and its multiple insect pollinators...
2017: Frontiers in Plant Science
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