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Juvenile Bipolar Disorder

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https://www.readbyqxmd.com/read/29788699/psychiatric-disorders-and-recidivism-among-korean-adolescents-on-probation-or-parole
#1
Yooli Lim, Eun-Jin Park, Bongseog Kim
Objective: The percentage of repeat offenders is increasing among juvenile offenders in Korea. The assessment and treatment of the mental health of young offenders may play an important role in reducing the recidivism rate of adolescents. This study examined the prevalence of psychiatric disorders among adolescents on probation or parole and the risk of recidivism associated with specific psychiatric disorders. Methods: We studied 120 adolescents on probation. The Mini-International Neuropsychiatric Interview and Conners' Rating Scale-Revised were used to diagnose psychiatric disorders...
May 24, 2018: Psychiatry Investigation
https://www.readbyqxmd.com/read/29540121/psychotropic-polypharmacy-among-youths-with-serious-emotional-and-behavioral-disorders-receiving-coordinated-care-services
#2
Benjamin Wu, Eric J Bruns, Ming-Hui Tai, Bethany R Lee, Ramesh Raghavan, Susan dosReis
OBJECTIVE: The study examined differences in psychotropic polypharmacy among youths with serious emotional and behavioral disorders who received coordinated care services (CCS) that used a wraparound model and a matched sample of youths who received traditional services. METHODS: A quasi-experimental design compared psychotropic polypharmacy one year before and one year after discharge from CCS. The cohort was youths with serious emotional and behavioral disorders who were enrolled in CCS from December 2009 through May 2014...
March 15, 2018: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/29446039/adhd-juvenile-bipolar-disorder-mimics-and-chameleons
#3
Ahmed Naguy
No abstract text is available yet for this article.
February 14, 2018: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/29317193/an-essential-role-for-neuregulin-4-in-the-growth-and-elaboration-of-developing-neocortical-pyramidal-dendrites
#4
Blanca Paramo, Sean Wyatt, Alun M Davies
Neuregulins, with the exception of neuregulin-4 (NRG4), have been shown to be extensively involved in many aspects of neural development and function and are implicated in several neurological disorders, including schizophrenia, depression and bipolar disorder. Here we provide the first evidence that NRG4 has a crucial function in the developing brain. We show that both the apical and basal dendrites of neocortical pyramidal neurons are markedly stunted in Nrg4-/- neonates in vivo compared with Nrg4+/+ littermates...
April 2018: Experimental Neurology
https://www.readbyqxmd.com/read/29228982/electroconvulsive-therapy-for-manic-state-with-mixed-and-psychotic-features-in-a-teenager-with-bipolar-disorder-and-comorbid-episodic-obsessive-compulsive-disorder-a-case-report
#5
Olof Rask, Klara Suneson, Eva Holmström, Beata Bäckström, Björn Axel Johansson
BACKGROUND: Comorbidity of bipolar disorder and obsessive-compulsive disorder is common in adolescence. Obsessive-compulsive disorder symptoms may be episodic and secondary to alterations in mood, and display specific features. Management of pediatric bipolar disorder-obsessive-compulsive disorder is challenging, as pharmacotherapy of obsessive-compulsive disorder may induce or exacerbate manic episodes and there is limited evidence of treatment efficacy. Electroconvulsive therapy is sparsely used in children and adolescents, but is documented to be a safe and efficacious intervention in adults with bipolar disorder...
December 12, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28942804/suicide-attempts-in-juvenile-bipolar-versus-major-depressive-disorders-systematic-review-and-meta-analysis
#6
REVIEW
Franco De Crescenzo, Giulia Serra, Francesco Maisto, Mai Uchida, Hilary Woodworth, Maria Pia Casini, Ross J Baldessarini, Stefano Vicari
OBJECTIVE: Suicide attempts are prevalent in association with major mood disorders, and risk is greater with bipolar disorder (BD) than major depressive disorder (MDD) in adults. There may be similar relationships in juvenile mood disorders, but the evidence has not been compiled systematically and quantitatively. METHOD: We searched for reports of studies comparing rates of suicide attempts in children or adolescents diagnosed with BD or MDD, and applied random-effects meta-analysis...
October 2017: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/28866299/clinical-experience-using-intranasal-ketamine-in-the-longitudinal-treatment-of-juvenile-bipolar-disorder-with-fear-of-harm-phenotype
#7
Demitri Papolos, Mark Frei, Daniel Rossignol, Steven Mattis, Laura C Hernandez-Garcia, Martin H Teicher
OBJECTIVES: Fear of Harm (FOH) is a pediatric onset phenotype of bipolar disorder (BD) characterized by BD plus treatment resistance, separation anxiety, aggressive obsessions, parasomnias, and thermal dysregulation. Intranasal ketamine (InK) in 12 youths with BD-FOH produced marked improvement during a two-week trial. Here we report on the open effectiveness and safety of InK in maintenance treatment of BD-FOH from the private practice of one author. METHODS: As part of a chart review, patients 18 years or older and parents of younger children responded to a clinical effectiveness and safety survey...
January 1, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28341336/valproic-acid-malabsorption-in-30-year-old-female-patient-case-study
#8
Anna Jopowicz, Agnieszka Piechal, Iwona Kurkowska-Jastrzębska
AIM: Valproic acid (VPA) is used in epilepsy treatment and as a stabilizer in bipolar affective disorder for over 40 years. Although, the pharmacokinetic properties of valproic acid are well known, it is often forgotten that the formulation of the drug significantly influences its gastrointestinal absorption. CASE: We are describing the case of 30 year-old female patient, diagnosed at the age of 13 with juvenile myoclonic epilepsy. Complete ineffectiveness of the treatment was caused by malabsorption of sodium valproate and valproic acid in the patient...
May 2017: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/28289475/combined-genome-wide-linkage-and-targeted-association-analysis-of-head-circumference-in-autism-spectrum-disorder-families
#9
M Woodbury-Smith, D A Bilder, J Morgan, L Jerominski, T Darlington, T Dyer, A D Paterson, H Coon
BACKGROUND: It has long been recognized that there is an association between enlarged head circumference (HC) and autism spectrum disorder (ASD), but the genetics of HC in ASD is not well understood. In order to investigate the genetic underpinning of HC in ASD, we undertook a genome-wide linkage study of HC followed by linkage signal targeted association among a sample of 67 extended pedigrees with ASD. METHODS: HC measurements on members of 67 multiplex ASD extended pedigrees were used as a quantitative trait in a genome-wide linkage analysis...
2017: Journal of Neurodevelopmental Disorders
https://www.readbyqxmd.com/read/28262260/-suicidal-attempts-in-child-and-adolescent-and-bipolar-disorders
#10
N Dugand, S Thümmler, C Pradier, F Askenazy
BACKGROUND: Child and adolescent psychiatrists are frequently confronted with suicide attempts and comorbid mood disorders. Diagnoses of juvenile bipolar disorders (BD) are rare and controversial and standardized assessment is helpful for a reliable diagnosis. The main objective of this study was to identify the number of juvenile bipolar disorder diagnoses according to DSM-5 criteria in a population of children and adolescents hospitalized for suicide attempts. Secondary objectives were the assessment of a patient's characteristics and the comparison of suicide attempt recurrence during 12 months of follow-up...
March 2, 2017: L'Encéphale
https://www.readbyqxmd.com/read/28119084/effects-of-amphetamine-on-pro-social-ultrasonic-communication-in-juvenile-rats-implications-for-mania-models
#11
K-Alexander Engelhardt, Eberhard Fuchs, Rainer K W Schwarting, Markus Wöhr
Communication is the act of information transfer between sender and receiver. In rats, vocal communication can be studied through ultrasonic vocalizations (USV). 50-kHz USV occur in appetitive situations, most notably juvenile play, likely expressing the sender׳s positive affective state. Such appetitive 50-kHz USV serve important pro-social communicative functions and elicit social exploratory and approach behavior in the receiver. Emission of 50-kHz USV can be induced pharmacologically by the administration of psychostimulant drugs, such as amphetamine...
March 2017: European Neuropsychopharmacology: the Journal of the European College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27988864/the-potential-relevance-of-docosahexaenoic-acid-and-eicosapentaenoic-acid-to-the-etiopathogenesis-of-childhood-neuropsychiatric-disorders
#12
REVIEW
Alessandra Tesei, Alessandro Crippa, Silvia Busti Ceccarelli, Maddalena Mauri, Massimo Molteni, Carlo Agostoni, Maria Nobile
Over the last 15 years, considerable interest has been given to the potential role of omega-3 polyunsaturated fatty acids (PUFAs) for understanding pathogenesis and treatment of neurodevelopmental and psychiatric disorders. This review aims to systematically investigate the scientific evidence supporting the hypothesis on the omega-3 PUFAs deficit as a risk factor shared by different pediatric neuropsychiatric disorders. Medline PubMed database was searched for studies examining blood docosahexaenoic acid (DHA) or eicosapentaenoic acid (EPA) status in children with neuropsychiatric disorders...
September 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/27134318/adult-onset-offenders-is-a-tailored-theory-warranted
#13
Amber L Beckley, Avshalom Caspi, Honalee Harrington, Renate M Houts, Tara Renae Mcgee, Nick Morgan, Felix Schroeder, Sandhya Ramrakha, Richie Poulton, Terrie E Moffitt
PURPOSE: To describe official adult-onset offenders, investigate their antisocial histories and test hypotheses about their origins. METHODS: We defined adult-onset offenders among 931 Dunedin Study members followed to age 38, using criminal-court conviction records. RESULTS: Official adult-onset offenders were 14% of men, and 32% of convicted men, but accounted for only 15% of convictions. As anticipated by developmental theories emphasizing early-life influences on crime, adult-onset offenders' histories of antisocial behavior spanned back to childhood...
September 1, 2016: Journal of Criminal Justice
https://www.readbyqxmd.com/read/27045389/bipolar-disorder-type-1-in-a-17-year-old-girl-with-wolfram-syndrome
#14
Jean Xavier, Nadège Bourvis, Antoine Tanet, Tatiana Ramos, Didier Perisse, Isabelle Marey, David Cohen, Angèle Consoli
OBJECTIVE: Wolfram syndrome (WS, MIM 222300) is a rare autosomal, recessive neurodegenerative disorder associated with mutations in WFS1, a gene that has been associated with bipolar disorder (BD). WS, characterized by the association of juvenile-onset diabetes mellitus (DM) and bilateral progressive optic atrophy (BPOA), encompasses several other clinical features, including cognitive impairments and psychiatric disorders. Detailed data on the psychiatric phenotype are still scarce, and how WS relates to BD is still unknown...
October 2016: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/26986855/structural-recovery-of-the-retina-in-a-retinoschisin-deficient-mouse-after-gene-replacement-therapy-by-solid-lipid-nanoparticles
#15
P S Apaolaza, A Del Pozo-Rodríguez, M A Solinís, J M Rodríguez, U Friedrich, J Torrecilla, B H F Weber, A Rodríguez-Gascón
X-linked juvenile retinoschisis (XLRS) is a retinal degenerative disorder caused by mutations in the RS1 gene encoding a protein termed retinoschisin. The disease is an excellent candidate for gene replacement therapy as the majority of mutations have been shown to lead to a complete deficiency of the secreted protein in the retinal structures. In this work, we have studied the ability of non-viral vectors based on solid lipid nanoparticles (SLN) to induce the expression of retinoschisin in photoreceptors (PR) after intravitreal administration to Rs1h-deficient mice...
June 2016: Biomaterials
https://www.readbyqxmd.com/read/26873182/juvenile-clinical-predictors-of-clinical-course-and-outcome-in-adult-bipolar-disorder
#16
COMMENT
Giulia Serra
No abstract text is available yet for this article.
April 2016: Lancet Psychiatry
https://www.readbyqxmd.com/read/26519764/attention-deficit-hyperactivity-disorder-its-pharmacotherapy-and-the-risk-of-developing-bipolar-disorder-a-nationwide-population-based-study-in-taiwan
#17
Liang-Jen Wang, Yu-Chiau Shyu, Shin-Sheng Yuan, Chun-Ju Yang, Kang-Chung Yang, Tung-Liang Lee, Sheng-Yu Lee
UNLABELLED: In this study, we aimed to evaluate the relationship between attention-deficit/hyperactivity disorder (ADHD) during childhood and subsequent diagnoses of bipolar disorder (BD), as well as to determine whether the pharmacotherapy for ADHD (methylphenidate and atomoxetine) influence the risks of developing BD. A nationwide cohort of patients newly diagnosed with ADHD (n = 144,920) and age- and gender-matching controls (n = 144,920) were found in Taiwan's National Health Insurance database from January 2000 to December 2011...
January 2016: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/26405242/predictors-of-rapid-reincarceration-in-mentally-ill-young-offenders
#18
John Kasinathan
OBJECTIVE: Describe characteristics of mentally ill young offenders released from custody and predictors of those who rapidly returned to custody. METHOD: Ambidirectional cohort study of 51 young males with mental disorders released from the largest New South Wales Juvenile Justice Centre (2005-2007), a health file audit at time of release and prospective determination of reincarceration. RESULTS: Overall 47% were Aboriginal, 43% originated from regional communities, substance disorders were highly prevalent and only 12% accessed prior community mental health care...
October 2015: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
https://www.readbyqxmd.com/read/26237382/cortical-volume-alterations-in-conduct-disordered-adolescents-with-and-without-bipolar-disorder
#19
Rene L Olvera, David C Glahn, Louise O'Donnell, Carrie E Bearden, Jair C Soares, Anderson M Winkler, Steven R Pliszka
BACKGROUND: There is increasing evidence that bipolar disorder (BD) and conduct disorder (CD) are co-occurring disorders. Magnetic resonance imaging has revealed differences in the structure and function of the frontal cortex in these disorders when studied separately; however, the impact of BD comorbidity on brain structure in adolescents with CD has not yet been examined. METHOD: We conducted an optimized voxel based morphometry (VBM) study of juvenile offenders with the following diagnoses: conduct disorder with comorbid bipolar disorder (CD-BD; n = 24), conduct disorder without bipolar disorder (CD; n = 24) and healthy controls (HC, n = 24)...
2014: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/26035191/precursors-of-bipolar-disorders-a-systematic-literature-review-of-prospective-studies
#20
REVIEW
Gianni L Faedda, Ciro Marangoni, Giulia Serra, Paola Salvatore, Gabriele Sani, Gustavo H Vázquez, Leonardo Tondo, Paolo Girardi, Ross J Baldessarini, Athanasios Koukopoulos
OBJECTIVE: To evaluate the presence of affective signs and symptoms as precursors of bipolar disorder in prospective studies, including assessment of their prevalence, duration, and predictive value. DATA SOURCES: We followed PRISMA guidelines to search PubMed, CINAHL, PsycINFO, EMBASE, SCOPUS, and ISI Web of Science databases to May 31, 2013, using the terms bipolar disorder AND (antecedent* OR predict* OR prodrom* OR prospect*) AND (diagnosis OR development). Hand searching of identified reports led to additional relevant references...
May 2015: Journal of Clinical Psychiatry
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