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https://www.readbyqxmd.com/read/28727692/short-term-outcomes-following-cytoreductive-surgery-and-heated-intra-peritoneal-chemotherapy-at-waikato
#1
Ngov Jasen Ly, Linus Wu, Ralph Van Dalen, Simione Lolohea
AIM: Pseudomyxoma peritonei is a rare disease that affects 1-2 per million population per year. Treatment with cytoreductive surgery with heated intraperitoneal chemotherapy (CRS with IPC) has been well described. The purpose of this study was to look at the short-term outcomes following CRS with IPC for all such patients treated in Waikato. METHOD: Records for all patients presenting to surgery for CRS with IPC were retrospectively reviewed. CRS with IPC was performed in accordance with the techniques described by Sugarbaker...
July 21, 2017: New Zealand Medical Journal
https://www.readbyqxmd.com/read/28722092/-predictive-factors-of-intestinal-necrosis-in-acute-mesenteric-vascular-occlusive-diseases
#2
Dafang Liu, Yingjiang Ye, Qiwei Xie, Mujun Yin, Xiaodong Yang, Bin Liang, Shan Wang
OBJECTIVE: To explore the predictive factors of intestinal necrosis in acute mesenteric vascular occlusive diseases and its significance for the timing of exploratory laparotomy. METHODS: This retrospective study enrolled 63 patients diagnosed as acute mesenteric vascular occlusive diseases at Peking University People's Hospital between July 1995 and June 2015. Univariate analysis and multivariate logistic regression analysis were used to identify predictive factors for intestinal necrosis...
July 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28720378/a-novel-technique-carbon-dioxide-gas-assisted-total-peritonectomy-diaphragm-and-intestinal-meso-stripping-in-open-surgery-for-advanced-ovarian-cancer-%C3%A3-ukurova-technique
#3
Ghanim Khatib, Ahmet Baris Guzel, Umran Kucukgoz Gulec, Mehmet Ali Vardar
OBJECTIVE: Most of the ovarian cancers are diagnosed at advanced stages. As peritoneal carcinomatosis increases, especially when it extends to the diaphragm and intestinal mesos, probability of obtaining complete cytoreduction is reduced. Complete cytoreduction (residue zero: R0) is one of the main factors affecting survival [1-3]. Here we present a novel technique of stripping the peritoneal surfaces as a part of cytoreductive surgery in such cases. METHODS: A 55year-old woman diagnosed with peritoneal carcinomatosis was considered appropriate for primary cytoreduction after assessment of her thorax-abdominopelvic tomography, which revealed resectable intra-abdominal disease...
July 15, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28712777/reproducibility-for-histologic-parameters-in-peritoneal-mesothelioma
#4
Douglas J Hartman, Alain Borczuk, Sanja Dacic, Alyssa Krasinskas
Histologic subtype is recognized as a prognostic factor in malignant pleural mesothelioma. Specifically, epithelial morphology is associated with a better prognosis than other subtypes and the same association is observed in peritoneal malignant mesothelioma. Recently, prognostic differences based on morphologic subtypes of epithelial peritoneal malignant mesothelioma were reported. Herein, we report the interobserver variability across four pathologists at three institutions. The authors independently reviewed 67 cases of malignant peritoneal epithelioid mesotheliomas and subclassified them according to their epithelial subtype: papillary, tubulopapillary, trabecular, micropapillary, solid and/or pleomorphic...
July 13, 2017: Human Pathology
https://www.readbyqxmd.com/read/28710573/sutureless-inguinal-hernia-repair-with-creation-of-a-peritoneal-lesion-in-children-a-novel-laparoscopic-technique-with-a-low-recurrence-rate
#5
Alfonso Galván Montaño, Paul Manuel Ali Ouddane Robles, Silvia García Moreno
BACKGROUND: Hernia repair represents about 25% of all pediatric surgeries. Repair can be done using an open or laparoscopic technique. The open approach has a reported recurrence rate of 1.2% but requires an additional incision to repair for a contralateral hernia. With the laparoscopic approach, no additional incision is needed but the recurrence rate has been reported to be as high as 4%. The objective of this study was to assess the safety and efficacy of a novel sutureless laparoscopic inguinal hernia repair that has the advantages of both approaches...
July 14, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28708664/esmolol-administration-to-control-tachycardia-in-an-ovine-model-of-peritonitis
#6
Koji Hosokawa, Fuhong Su, Fabio Silvio Taccone, Emiel Hendrik Post, Adriano José Pereira, Antoine Herpain, Jacques Creteur, Jean-Louis Vincent
BACKGROUND: Excessive adrenergic signaling may be harmful in sepsis. Using β-blockers to reduce sympathetic overactivity may modulate sepsis-induced cardiovascular, metabolic, immunologic, and coagulation alterations. Using a randomized ovine fecal peritonitis model, we investigated whether administration of a short-acting β-blocker, esmolol, could control tachycardia without deleterious effects on hemodynamics, renal perfusion, cerebral perfusion, cerebral metabolism, or outcome. METHODS: After induction of fecal peritonitis, 14 anesthetized, mechanically ventilated, and hemodynamically monitored adult female sheep were randomly assigned to receive a continuous intravenous infusion of esmolol to control heart rate between 80 and 100 bpm (n = 7) or a saline infusion (control group, n = 7)...
July 13, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28707042/validity-of-neoadjuvant-chemotherapy-with-docetaxel-cisplatin-and-s-1-for-resectable-locally-advanced-gastric-cancer
#7
Kinro Sasaki, Shinichi Onodera, Kichiro Otsuka, Hitoshi Satomura, Eigo Kurayama, Tsukasa Kubo, Masakazu Takahashi, Jun Ito, Masanobu Nakajima, Satoru Yamaguchi, Kazuhito Miyachi, Hiroyuki Kato
Gastrectomy with D2 lymphadenectomy plus postoperative chemotherapy is the standard treatment for resectable locally advanced gastric cancer in Japan. However, the prognosis of patients with serosa-positive tumors remains unsatisfactory because of peritoneal recurrence. This study aimed to investigate the validity of neoadjuvant therapy with docetaxel, cisplatin, and S-1 (DCS) in patients with locally advanced gastric cancer. Thirty patients with locally advanced gastric cancer underwent neoadjuvant DCS therapy at Dokkyo Medical University Hospital between June 2013 and October 2015...
August 2017: Medical Oncology
https://www.readbyqxmd.com/read/28701190/a-novel-algorithm-for-the-treatment-strategy-for-advanced-epithelial-ovarian-cancer-consecutive-imaging-frailty-assessment-and-diagnostic-laparoscopy
#8
Kyung Jin Eoh, Jung Won Yoon, Jung-Yun Lee, Eun Ji Nam, Sunghoon Kim, Sang Wun Kim, Young Tae Kim
BACKGROUND: This study aimed to evaluate the perioperative outcomes and prognostic impact of the consecutive steps of imaging, frailty assessment, and diagnostic laparoscopy (DLS) in patients with advanced epithelial ovarian cancer (EOC). METHODS: Patients diagnosed with EOC during 2012-2015 were analyzed retrospectively. Surgical and survival outcomes were compared between three treatment groups: patients without high tumor dissemination (HTD) who underwent primary debulking surgery (PDS group); patients with HTD who underwent DLS (DLS group); and patients with HTD diagnosed by cytological confirmation of malignancy followed by neoadjuvant chemotherapy (NACT group)...
July 12, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28700008/animal-model-of-continuous-peritoneal-lavage-with-vacuum-peritoneostomy
#9
Adilson Costa Rodrigues, Luana Carla Dos Santos, Denise Aya Otsuki, Karen Ruggeri Saad, Paulo Fernandes Saad, Edna Frasson de Souza Montero, Edivaldo Massazo Utiyama
Purpose: To establish and evaluate the feasibility of continuous peritoneal lavage with vacuum peritoneostomy in an animal model. Methods: Eight pigs aged 3-4 months, females, were anesthetized and submitted to laparotomy and installation of a continuous peritoneal lavage with vacuum peritoneostomy. The sta-bility of the system, the physiological effects of washing with NaCl 0.9% and the sys-tem clearance were evaluated. Results: Stability of vacuum peritoneostomy was observed, with no catheter leaks or obstructions and the clearance proved adequate, however, the mean volume of fluids aspirated by the peritoneostomy at the end of the experiment was higher than the volume infused by the catheters (p=0...
June 2017: Acta Cirúrgica Brasileira
https://www.readbyqxmd.com/read/28698253/outcomes-of-corynebacterium-peritonitis-a-multicenter-registry-analysis
#10
Htay Htay, Yeoungjee Cho, Elaine M Pascoe, Darsy Darssan, Carmel M Hawley, Philip A Clayton, Monique Borlace, Sunil V Badve, Kamal Sud, Neil C Boudville, Stephen P McDonald, David W Johnson
BACKGROUND: Corynebacterium is a rare cause of peritonitis that is increasingly being recognized in peritoneal dialysis (PD) patients. The aims of this study were to compare Corynebacterium peritonitis outcomes with those of peritonitis caused by other organisms and to examine the effects of type and duration of antibiotic therapy on outcomes of Corynebacterium peritonitis. METHODS: Using Australia and New Zealand Dialysis and Transplant Registry (ANZDATA) data, we included all PD patients who developed peritonitis in Australia between 2004 and 2014...
July 11, 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/28695556/changing-trends-in-end-stage-renal-disease-patients-with-diabetes
#11
Yimin Lu, Christina Stamm, Dina Nobre, Menno Pruijm, Daniel Teta, Anne Cherpillod, Georges Halabi, Olivier Phan, Zina Fumeaux, Roberto Bullani, Thierry Gauthier, Claudine Mathieu, Michel Burnier, Anne Zanchi
BACKGROUND: Worldwide, diabetes has become the most common cause of end-stage renal disease (ESRD), yet Swiss data are largely lacking. METHODS: This observational study examined ESRD patients with diabetes mellitus (ESRD-DM) at end of 2009 and 2014. The prevalence and characteristics of ESRD-DM patients were collected in all dialysis facilities in the Canton of Vaud of Switzerland in 2009 and in 2014, and the 5-year mortality rate was assessed. RESULTS: A total of 107 and 140 ESRD-DM patients underwent dialysis at end of 2009 and 2014, respectively...
July 11, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/28693216/trifluridine-tipiracil-increases-survival-rates-in-peritoneal-dissemination-mouse-models-of-human-colorectal-and-gastric-cancer
#12
Norihiko Suzuki, Fumio Nakagawa, Teiji Takechi
A number of patients exhibit peritoneal dissemination of gastric or colorectal cancer, which is a predominant cause of cancer-associated mortality. Currently, there is no markedly effective treatment available. The present study was designed to determine the efficacy of trifluridine/tipiracil (TFTD), formerly known as TAS-102, which is used for the treatment of patients with unresectable advanced or recurrent colorectal cancer refractory to standard therapies. Four colorectal cancer cell lines and one gastric cancer cell line were intraperitoneally inoculated into nude mice, as models of peritoneal dissemination...
July 2017: Oncology Letters
https://www.readbyqxmd.com/read/28690217/-clinical-characteristics-and-the-factors-relevant-to-peritoneal-transport-function-in-patients-with-continuous-ambulatory-peritoneal-dialysis
#13
Yang Xie, Hao Zhang, Jianwen Wang, Jun Liu, Bin Yi, Ke Zhang, Jishi Liu
To observe the clinical characteristics with different peritoneal transport type in patients with continuous ambulatory peritoneal dialysis (CAPD), and to investigate the factors associated with peritoneal transport function.
 Methods: The clinical data of 158 CAPD patients were analyzed retrospectively. According to peritoneal equilibration test, a method for evaluation of the peritoneal transport function, the patients were divided into 2 groups: a high average and high peritoneal transport group (Group A, n=84) and a low average and low peritoneal transport group (Group B, n=74)...
June 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28689443/does-having-a-gastrectomy-delay-time-to-feeding-and-prolong-hospital-stay-in-patients-undergoing-cytoreductive-surgery-and-hyperthermic-intraperitoneal-chemotherapy
#14
Nicholas B Shannon, Grace Hwei Ching Tan, Claramae Shulyn Chia, Khee Chee Soo, Melissa Ching Teo
AIM: Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) are routinely used to treat selected patients with peritoneal carcinomatosis, but can be associated with prolonged hospital stay, significant morbidity and mortality. Our objective was to assess whether patients undergoing gastrectomy as part of CRS/HIPEC were at increased risk of delayed feeding time and prolonged hospital stay. METHOD: 214 consecutive patients with peritoneal carcinomatosis treated with CRS/HIPEC between 2001 and 2016 were stratified by whether CRS included gastrectomy (n = 19, 9%) and compared...
July 9, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28686967/the-anti-inflammatory-and-antinociceptive-activity-of-albumins-from-crotalaria-retusa-seeds
#15
Diego Passos Aragão, Bruna da Silva Souza, Tarcisio Vieira de Brito, Lucas de Araújo Bastos Santana, Renata Mariana de Paiva Silva, Ana Patrícia de Oliveira, Anna Carolina Toledo da Cunha Pereira, Gustavo Portela Ferreira, André Luiz Dos Reis Barbosa, Jefferson Soares de Oliveira
Seeds of Crotalaria retusa L. are used in popular medicine because of their pharmacological properties. The albumin fraction obtained from its seeds contains lectin, a protein known to have analgesic and anti-inflammatory properties. Thus, albumins extracted from C. retusa were investigated for their anti-inflammatory and antinociceptive effects. The intraperitoneal administration of different doses of albumins (5, 10 or 20mg/kg) significantly inhibited the mice paw edema induced by carrageenan (maximum inhibition rate of 80...
July 4, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28686925/recurrent-gastric-cancer-metastasizing-to-the-bone-marrow-a-case-report-of-a-rare-presentation
#16
Ernest Fonocho, Nail Aydin, Srini Reddy, Subhasis Misra
INTRODUCTION: Gastric cancer notoriously recurs post curative surgical resection. While there may be visceral metastasis to peritoneal surfaces, bone marrow involvement may also occur although with rarity. We present a case report of recurrent gastric cancer with bone marrow metastasis in a patient with no evidence of systemic disease on follow-up for two years post surgical resection. This case demonstrates the need of heightened clinical suspicion in these patients. METHODS: We reviewed the medical records of a patient who presented with metastatic gastric adenocarcinoma to the bone marrow two years post R0 subtotal gastrectomy with Roux-en-Y gastrojejunostomy without evidence of systemic disease on follow up for two years...
June 24, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28683053/assessing-the-safety-of-expanded-polytetrafluoroethylene-synthetic-grafts-in-living-donor-liver-transplantation-graft-migration-into-hollow-viscous-organs-diagnosis-and-treatment-options
#17
Shih-Chao Hsu, Ashok Thorat, Horng-Ren Yang, Kin-Shing Poon, Ping-Chun Li, Chun-Chieh Yeh, Te-Hung Chen, Long-Bin Jeng
BACKGROUND Our recent studies have highlighted the importance and safety of backtable venoplasty for middle hepatic vein (MHV) and inferior right hepatic veins (IRHV) reconstruction using expanded polytetrafluoroethylene (ePTFE) vascular grafts. In this study, we aim to analyze the complications associated with ePTFE graft use and discuss the management of the rare, but, potentially life threatening complications directly related to ePTFE conduits. MATERIAL AND METHODS From January 2012 to October 2015 a total of 397 patients underwent living donor liver transplantation (LDLT)...
July 6, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28682966/management-of-low-colorectal-anastomotic-leakage-in-the-laparoscopic-era-more-than-a-decade-of-experience
#18
Stephen Alexander Boyce, Craig Harris, Andrew Stevenson, John Lumley, David Clark
BACKGROUND: Anastomotic leak after colorectal surgery increases postoperative mortality, cancer recurrence, permanent stoma formation, and poor bowel function. Anastomosis between the colon and rectum is a particularly high risk. Traditional management mandates laparotomy, disassembly of the anastomosis, and formation of an often-permanent stoma. After laparoscopic colorectal surgery it may be possible to manage anastomotic failure with laparoscopy, thus avoiding laparotomy. OBJECTIVE: The purpose of this study was to determine the feasibility of the laparoscopic management of failed low colorectal anastomoses...
August 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28682568/-peritoneal-dialysis-in-italy-the-fourth-gsdp-sin-census-2012
#19
Giancarlo Marinangeli, Gianfranca Cabiddu, Loris Neri, Giusto Viglino, Roberto Corciulo, Anna Rachele Rocca, Alessandro Laudon, Viviana Finato
OBJECTIVE: To know PD modalities and results in Italy. METHODS: The Census was carried out by means of an on-line questionnaire in all the 224 non-pediatric public centers which performed PD in 2012. The results were compared with those of previous Censuses. RESULTS: Incidence. In 2012 PD was begun (first treatment for ESRD) by 1,433 pts (CAPD: 54.3%) and HD by 4,700 pts (%PD-incidence= Cs-12: 23.4%; Cs-10: 23.3%; Cs-08: 22.8%; Cs-05: 24.2%; p=NS), with a further increase in incremental PD (Cs-12: 28...
April 2017: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/28680295/risk-factors-of-mortality-from-all-asbestos-related-diseases-a-competing-risk-analysis
#20
Rafael Abós-Herràndiz, Teresa Rodriguez-Blanco, Isabel Garcia-Allas, Isabel-Magdalena Rosell-Murphy, Constança Albertí-Casas, Josep Tarrés, Illona Krier-Günther, Xavier Martinez-Artés, Ramon Orriols, Isidre Grimau-Malet, Jaume Canela-Soler
BACKGROUND: The mortality from all malignant and nonmalignant asbestos-related diseases remains unknown. The authors assessed the incidence and risk factors for all asbestos-related deaths. METHODS: The sample included 544 patients from an asbestos-exposed community in the area of Barcelona (Spain), between Jan 1, 1970, and Dec 31, 2006. Competing risk regression through a subdistribution hazard analysis was used to estimate risk factors for the outcomes. RESULTS: Asbestos-related deaths were observed in 167 (30...
2017: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
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