keyword
https://read.qxmd.com/read/38652004/comprehensive-characterization-of-hearing-loss-and-tinnitus-in-military-affiliated-and-non-military-affiliated-individuals
#1
JOURNAL ARTICLE
Namitha Jain, Yihsin Tai, Caterina Wilson, Elsa C Granato, Carlos Esquivel, Anthony Tsao, Fatima T Husain
PURPOSE: Military-affiliated individuals (MIs) are at a higher risk of developing hearing loss and tinnitus. While these disorders are well-studied in MIs, their impact relative to non-military-affiliated individuals (non-MIs) remains understudied. Our study compared hearing, speech-in-noise (SIN) perception, and tinnitus characteristics between MIs and non-MIs. METHOD: MIs ( n = 84) and non-MIs ( n = 193) underwent hearing threshold assessment and Quick Speech-in-Noise Test...
April 23, 2024: American Journal of Audiology
https://read.qxmd.com/read/38651852/vitiligo-as-a-first-sign-of-vogt-koyanagi-harada-disease
#2
JOURNAL ARTICLE
Marija Vukojević, Nenad Vukojevic, Ante Vuković, Borna Rupčić, Mislav Blažević, Ante Blažević
Vogt-Koyanagi-Harada (VKH) disease is a multisystem disorder characterized by bilateral granulomatous panuveitis resulting in serous retinal detachments, disk edema, and a sunset glow fundus development. Furthermore, it is associated with various extraocular findings, such as tinnitus, hearing loss, vertigo, poliosis, and vitiligo (1). VKH is considered to be an autoimmune disease mediated by T-cells targeting melanocyte antigen tyrosinase peptide (2). Moreover, VKH more often occurs in individuals with a genetic predisposition to the disease, including those of Asian and Hispanic heritage (3)...
December 2023: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/38651553/binaural-hearing-in-monaural-conductive-or-mixed-hearing-loss-fitted-with-unilateral-bonebridge
#3
JOURNAL ARTICLE
Andrea Canale, Anastasia Urbanelli, Roberto Albera, Maria Gragnano, Valerio Bordino, Giuseppe Riva, Eugenio Sportoletti Baduel, Andrea Albera
OBJECTIVE: To determine the benefits of binaural hearing rehabilitation in patients with monaural conductive or mixed hearing loss treated with a unilateral bone conduction implant (BCI). METHODS: This monocentric study includes 7 patients with monaural conductive or mixed hearing loss who underwent surgical implantation of a unilateral BCI (Bonebridge, Med-El). An ITA Matrix test was performed by each patient included in the study - without and with the BCI and in three different settings - to determine the summation effect, squelch effect and head shadow effect...
April 2024: Acta Otorhinolaryngologica Italica
https://read.qxmd.com/read/38649993/enhancing-biostatistics-education-for-medical-students-in-poland-factors-influencing-perception-and-educational-recommendations
#4
JOURNAL ARTICLE
Michal Ordak
BACKGROUND: A number of recommendations for the teaching of biostatistics have been published to date, however, student opinion on them has not yet been studied. For this reason, the aim of the manuscript was to find out the opinions of medical students at universities in Poland on two forms of teaching biostatistics, namely traditional and practical, as well as to indicate, on the basis of the results obtained, the related educational recommendations. METHODS: The study involved a group of 527 students studying at seven medical faculties in Poland, who were asked to imagine two different courses...
April 22, 2024: BMC Medical Education
https://read.qxmd.com/read/38649854/prevalence-associated-risk-factors-and-patient-and-economic-impact-of-multiple-sensory-impairment-in-a-multi-ethnic-elderly-population-in-singapore-the-pioneer-study
#5
JOURNAL ARTICLE
Preeti Gupta, Aurora Chan, Vu Tai-Anh, Ryan E K Man, Eva K Fenwick, Amudha Aravindhan, Chay Junxing, Joanne M Wood, Alex A Black, Jia Hui Ng, Ching-Yu Cheng, Charumathi Sabanayagam, Ecosse L Lamoureux
BACKGROUND: To determine the prevalence, risk factors; and impact on patient health and economic outcomes across the laterality spectrum of multiple sensory impairment (MSI) in a multi-ethnic older Asian population. METHODS: In this population-based study of Singaporeans aged ≥ 60 years, MSI was defined as concomitant vision (visual acuity > 0.3 logMAR), hearing (pure-tone air conduction average > 25 dB), and olfactory (score < 12 on the Sniffin' Sticks test) impairments across the spectrum of laterality (any, unilateral, combination [of unilateral and bilateral], and bilateral)...
April 22, 2024: BMC Public Health
https://read.qxmd.com/read/38649797/genetic-and-phenotypic-analysis-of-225-chinese-children-with-developmental-delay-and-or-intellectual-disability-using-whole-exome-sequencing
#6
JOURNAL ARTICLE
Heqian Ma, Lina Zhu, Xiao Yang, Meng Ao, Shunxiang Zhang, Meizhen Guo, Xuelin Dai, Xiuwei Ma, Xiaoying Zhang
Developmental delay (DD), or intellectual disability (ID) is a very large group of early onset disorders that affects 1-2% of children worldwide, which have diverse genetic causes that should be identified. Genetic studies can elucidate the pathogenesis underlying DD/ID. In this study, whole-exome sequencing (WES) was performed on 225 Chinese DD/ID children (208 cases were sequenced as proband-parent trio) who were classified into seven phenotype subgroups. The phenotype and genomic data of patients with DD/ID were further retrospectively analyzed...
April 22, 2024: BMC Genomics
https://read.qxmd.com/read/38649691/single-unit-data-for-sensory-neuroscience-responses-from-the-auditory-nerve-of-young-adult-and-aging-gerbils
#7
JOURNAL ARTICLE
Amarins N Heeringa
This dataset was collected to study the functional consequences of age-related hearing loss for the auditory nerve, which carries acoustic information from the periphery to the central auditory system. Using high-impedance glass electrodes, raw voltage traces and spike times were recorded from more than one thousand single fibres of the auditory nerve of young-adult, middle-aged, and old Mongolian gerbils raised in a quiet environment. The dataset contains not only responses to simple acoustic stimuli to characterize the fibres, but also to more complex stimuli, such as speech logatomes in background noise and Schroeder-phase stimuli...
April 22, 2024: Scientific Data
https://read.qxmd.com/read/38649263/a-retrospective-analysis-of-liraglutide-glp-1-agonist-use-in-a-chinchilla-chinchilla-lanigera-model-of-auditory-blast-injury
#8
JOURNAL ARTICLE
Deidra Marchi, Clarissa Cerepaka, Lori Garman, Wendy R Williams
Chinchillas are a relatively novel research model compared with other rodent species. They require special considerations when it comes to their husbandry and daily care. Chinchillas tend to be shy animals that are well adapted to masking clinical signs of illness. These characteristics can make them a difficult species to maintain in a research setting. The authors' institution has maintained chinchillas and established standardized daily animal care procedures for them. Chinchillas are most commonly used for auditory research...
April 22, 2024: Comparative Medicine
https://read.qxmd.com/read/38648830/audiometry-interpretation-for-hearing-loss-in-adults
#9
JOURNAL ARTICLE
Mandi Sehgal, Alexandra Sellers, Wendy S Biggs
Hearing loss is a prevalent, chronic condition in the United States; it is often gradual and progressive and is underreported by patients and undertreated by physicians. The impaired ability to effectively hear and communicate may result in negative emotional, cognitive, economic, and social consequences for individuals and may pose a safety risk. Questionnaires and smartphone apps are available to help identify and evaluate self-perceived hearing loss. Physicians should assess for objective hearing impairment when the patient or family member raises a concern or if cognitive or mood symptoms are present that could be influenced by hearing loss...
April 2024: American Family Physician
https://read.qxmd.com/read/38648562/inferential-comprehension-abilities-in-french-speaking-preschoolers-exposed-to-neglect-in-the-early-longitudinal-language-and-neglect-study
#10
JOURNAL ARTICLE
Pamela Filiatrault-Veilleux, Chantal Desmarais, Caroline Bouchard, Breanne Esau, Audette Sylvestre
PURPOSE: Using a longitudinal design, this study aimed to describe inferential comprehension abilities of neglected French-speaking preschool children from 42 to 66 months of age in comparison to non-neglected peers, to examine the association with receptive vocabulary, and to determine whether rates of change in inferential abilities over time was stable between the two group conditions. METHOD: An inferential comprehension task and the French version of the Peabody Picture Vocabulary Test-Fourth Edition were administered to a group of neglected children ( n = 37-40) and to a group of same-age non-neglected children ( n = 71-91) at 42, 54, and 66 months old, as part of the Early Longitudinal Language and Neglect study...
April 22, 2024: Journal of Speech, Language, and Hearing Research: JSLHR
https://read.qxmd.com/read/38648534/viewpoint-on-the-benefit-of-hearing-care-on-cognitive-health
#11
JOURNAL ARTICLE
Maren Stropahl, Sigrid Scherpiet, Stefan Launer
PURPOSE: The purpose of this article is to provide a viewpoint on the recently published results showing the positive effect hearing intervention can have on mitigating the risk of cognitive decline in elderly individuals with hearing impairment. We intend to trigger a broader discussion on the implications of these results from an implementation science perspective. METHODS: Recently published results were reviewed and contextualized. RESULTS: In our view, these recent findings provide a great opportunity for hearing care professionals to change the perspective on hearing care being an essential service that contributes not only to managing challenges with audibility but to enabling healthy living and aging...
April 22, 2024: American Journal of Audiology
https://read.qxmd.com/read/38648533/evaluating-hearing-status-and-word-recognition-ability-in-the-hmong-population-using-four-validated-monosyllabic-white-hmong-dialect-word-recognition-tests
#12
JOURNAL ARTICLE
Maichou Lor, Elizabeth O'Donnell, Roger Brown, Amanda E Mravec, Sara M Misurelli
PURPOSE: The study's aims were (a) to evaluate hearing status and (b) word recognition ability of Hmong speakers using four validated monosyllabic word recognition tests in the White Hmong dialect and (c) to assess the relationship between the participant's language and the average word recognition percent correct scores, adjusting for age, gender, and degree of hearing loss. METHOD: Participants listened to two randomly assigned validated Hmong word lists (male/female talker) for each ear...
April 22, 2024: American Journal of Audiology
https://read.qxmd.com/read/38647666/-cochlear-implantation-in-patients-with-autoimmune-hearing-loss
#13
JOURNAL ARTICLE
Maximilian Armstorfer, Lennart Weitgasser, Stefan Tschani, Sebastian Rösch
BACKGROUND: Autoimmune inner ear disease (AIED) manifests with recurrent fluctuating sensorineural hearing loss and vestibular symptoms. Treatment includes steroids and a variety of immunosuppressants. Despite adequate treatment, sensorineural hearing loss can be progressive to the point of deafness. In these patients, a cochlear implant (CI) is indicated. We present the case of a 25-year-old male who underwent cochlear implantation in the left ear. After implantation we noticed brisk variations in impedances which were related to application of the previously prescribed tumor necrosis alpha (TNFα) inhibitor adalimumab...
April 22, 2024: HNO
https://read.qxmd.com/read/38647665/-to-implant-or-not-to-implant-electrically-evoked-auditory-brainstem-response-audiometry-for-decision-making-in-vestibular-schwannoma-resection-with-ci
#14
REVIEW
Valerie Dahm, Anselm Joseph Gadenstaetter, Christoph Arnoldner
Vestibular schwannomas (VS) are often associated with debilitating hearing loss. Therefore, preservation and rehabilitation of hearing have become major therapeutic goals of VS management. Recently, cochlear implantation (CI) has been established as an effective treatment option for VS-associated hearing loss. Nevertheless, the integrity and proper function of the cochlear nerve must be evaluated before conducting CI to ensure optimal CI outcomes. Various methods to determine cochlear nerve integrity and functionality have emerged in the last few years...
April 22, 2024: HNO
https://read.qxmd.com/read/38647204/noninvasive-twin-genotyping-for-recessive-monogenic-disorders-by-relative-haplotype-dosage
#15
JOURNAL ARTICLE
Lingrong Kong, Zhenhua Zhao, Xinyu Fu, Huanyun Li, Jingqi Zhu, Di Wu, Xiangdong Kong, Luming Sun
OBJECTIVE: To establish a haplotype-based noninvasive prenatal testing (NIPT) workflow for single-gene recessive disorders that adapt to dizygotic (DZ) twin pregnancies. METHOD: Twin pregnancies at risk of Duchenne muscular dystrophy, Becker muscular dystrophy, hemophilia B, spinal muscular atrophy, phenylketonuria, and nonsyndromic hearing loss were recruited. For subsequent analysis, capture sequencing targeting highly heterozygotic single nucleotide polymorphism sites was conducted...
April 22, 2024: Prenatal Diagnosis
https://read.qxmd.com/read/38646219/parents-perception-and-use-of-skin-to-skin-care-in-jeddah-saudi-arabia-a-cross-sectional-study
#16
JOURNAL ARTICLE
Ahmad Ismail, Amnah Mahdi, Karimeh M Al-Nuaimi
BACKGROUND: Skin-to-skin care (SSC) between newborns and their parents provides many positive outcomes for both newborns and their parents. However, there is a lack of research assessing the perception of parents, especially fathers, of SSC in Saudi Arabia. PURPOSE: The aim of the study is to assess parents' perception of SSC in Saudi Arabia. METHODS: This cross-sectional study used an online survey. Data were collected from a convenience sample of 140 parents of hospitalized neonates between January and June 2023...
March 2024: Curēus
https://read.qxmd.com/read/38643754/psychometric-validation-of-a-hearing-screening-questionnaire-for-preschoolers-based-on-language-development-evaluation-by-caregivers
#17
JOURNAL ARTICLE
Lorena Gabrielle Ribeiro Bicalho de Castro, Sirley Alves da Silva Carvalho, Ana Cristina Côrtes Gama, Denise Utsch Gonçalves, Luciana Macedo Resende, Fabrice Giraudet, Amelia Augusta de Lima Friche, Erika Parlato-Oliveira, Paul Avan
INTRODUCTION: This study aimed to validate three age-adjusted versions of a Hearing Screening Questionnaire for Preschoolers, in Brazilian Portuguese, based on parents' perception of their children's hearing and oral language. METHODS: Psychometric validation was conducted on three questionnaires, each comprising nine items with Yes/No responses. Three items focused on hearing screening at birth, and six assessed hearing and oral language. The study included 152 parents and their children, who attended day care centers in Belo Horizonte, Brazil...
April 20, 2024: Folia Phoniatrica et Logopaedica
https://read.qxmd.com/read/38642031/regression-of-endolymphatic-hydrops-in-patient-with-meniere-s-disease-treated-with-vestibular-neurectomy-a-case-report
#18
JOURNAL ARTICLE
Agnieszka Jasińska-Nowacka, Tomasz Wojciechowski, Emilia Wnuk, Kazimierz Niemczyk
Vestibular neurectomy is an effective method eliminating vertigo attacks in patients suffering from disabling Meniere's disease with no clinical improvement despite conservative and intratympanic therapy. Magnetic resonance imaging allows in vivo evaluation of changes manifesting in the inner ear after treatment; however, downgrading of the endolymphatic hydrops after vestibular neurectomy had not been previously described in the literature. In the present article, a case of a patient with unilateral severe Meniere's disease treated with selective vestibular nerve section from middle fossa approach was described...
April 20, 2024: Ear, Nose, & Throat Journal
https://read.qxmd.com/read/38640886/long-term-follow-up-of-a-series-of-24-congenital-cmv-infected-babies-with-false-negative-amniocentesis
#19
JOURNAL ARTICLE
Caroline De Coninck, Catherine Donner, Elena Costa, Serine Abbas, Marie-Luce Delforge
BACKGROUND: Congenital CMV infection is the most common congenital infection worldwide and a major cause of neurological impairment and sensorineural hearing loss. Fetal CMV infection is confirmed by a positive PCR test in the amniotic fluid (amniocentesis performed after 18-20 weeks of gestation and at least 8 weeks after maternal infection). However, despite a negative antenatal CMV PCR result, some newborns can be tested positive at birth. Although not widely documented, the prognosis for these babies appears to be good...
April 8, 2024: Journal of Clinical Virology
https://read.qxmd.com/read/38640279/case-report-of-a-novel-mutation-in-the-tnc-gene-in-chinese-patients-with-nonsyndromic-hearing-loss
#20
JOURNAL ARTICLE
Shouxia Li, Shurui Li, Dingli Chen, Subin Zhao, Cairu Liu, Ruimin Zhang, Yongxue Chen, Xiangrui Guo, Xuedong Song
RATIONALE: Hereditary hearing loss is known to exhibit a significant degree of genetic heterogeneity. Herein, we present a case report of a novel mutation in the tenascin-C (TNC) gene in Chinese patients with nonsyndromic hearing loss (NSHL). PATIENT CONCERNS: This includes a young deaf couple and their 2-year-old baby. DIAGNOSES: Based on the clinical information, hearing test, metagenomic next-generation sequencing (mNGS), Sanger sequencing, protein function and structure analysis, and model prediction, in our case, the study results revealed 2 heterozygous mutations in the TNC gene (c...
April 19, 2024: Medicine (Baltimore)
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