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https://www.readbyqxmd.com/read/28639415/anti-vascular-endothelial-growth-factor-for-diabetic-macular-oedema-a-network-meta-analysis
#1
REVIEW
Gianni Virgili, Mariacristina Parravano, Jennifer R Evans, Iris Gordon, Ersilia Lucenteforte
BACKGROUND: Diabetic macular oedema (DMO) is a common complication of diabetic retinopathy. Antiangiogenic therapy with anti-vascular endothelial growth factor (anti-VEGF) modalities can reduce oedema and thereby improve vision and prevent further visual loss. These drugs have replaced laser photocoagulation as the standard of care for people with DMO. OBJECTIVES: The 2014 update of this review found high-quality evidence of benefit with antiangiogenic therapy with anti-VEGF modalities, compared to laser photocoagulation, for the treatment of DMO...
June 22, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28636099/spectators-or-participants-how-can-setac-become-more-engaged-in-international-climate-change-research-programs
#2
Ralph G Stahl, Jennifer L Stauber, William H Clements
Environmental toxicologists and chemists have been crucial to evaluating the chemical fate and toxicological effects of environmental contaminants, including chlorinated pesticides, before and after Rachel Carson's publication of Silent Spring in 1962. Like chlorinated pesticides previously, global climate change is widely considered to be one of the most important environmental challenges of our time. Over the past 30 yr, climate scientists and modelers have shown that greenhouse gases such as CO2 and CH4 cause radiative forcing (climate forcing) and lead to increased global temperatures...
June 21, 2017: Environmental Toxicology and Chemistry
https://www.readbyqxmd.com/read/28604491/spinal-flexibility-assessment-on-the-patients-with-adolescent-idiopathic-scoliosis-ais-a-literature-review
#3
Chen He, Man-Sang Wong
STUDY DESIGN: Literature review OBJECTIVE.: To review the contemporary methods for spinal flexibility assessment on the patients with adolescent idiopathic scoliosis (AIS). SUMMARY OF BACKGROUND DATA: Spinal flexibility is one of the essential parameters for clinical decisions on the patients with AIS. Various methods of spinal flexibility assessment are proposed, but which method(s) could better reveal spinal flexibility or predict treatment effect is unclear. METHODS: The databases of AbleData, IBSS, Academic Search Premier, MEDLINE/PubMed, CINAHL, Recal Legacy, REHABDATA, Embase and Web of Science were searched...
June 9, 2017: Spine
https://www.readbyqxmd.com/read/28562238/the-orthopedic-trauma-symposium-improving-care-of-orthopedic-injuries-in-haiti
#4
Ryan Normore, Helena Greene, Allison DeLong, Andrew Furey
BACKGROUND: Although single-trip volunteer medical teams can provide much-needed acute trauma care following natural disasters, their ability to leave a legacy of improved care in the region is often limited. One way to improve treatment of traumatic injuries is through conference-based teaching, such as the Orthopedic Trauma Symposium (OTS), which took place in Haiti in 2014. However, there is little research evaluating the effectiveness of such teaching tools. We evaluated the OTS and the potential benefits of future iterations of the course...
June 1, 2017: Canadian Journal of Surgery. Journal Canadien de Chirurgie
https://www.readbyqxmd.com/read/28560765/an-amazonian-rainforest-and-its-fragments-as-a-laboratory-of-global-change
#5
William F Laurance, José L C Camargo, Philip M Fearnside, Thomas E Lovejoy, G Bruce Williamson, Rita C G Mesquita, Christoph F J Meyer, Paulo E D Bobrowiec, Susan G W Laurance
We synthesize findings from one of the world's largest and longest-running experimental investigations, the Biological Dynamics of Forest Fragments Project (BDFFP). Spanning an area of ∼1000 km(2) in central Amazonia, the BDFFP was initially designed to evaluate the effects of fragment area on rainforest biodiversity and ecological processes. However, over its 38-year history to date the project has far transcended its original mission, and now focuses more broadly on landscape dynamics, forest regeneration, regional- and global-change phenomena, and their potential interactions and implications for Amazonian forest conservation...
May 30, 2017: Biological Reviews of the Cambridge Philosophical Society
https://www.readbyqxmd.com/read/28547884/lack-of-transgene-and-glyphosate-effects-on-yield-and-mineral-and-amino-acid-content-of-glyphosate-resistant-soybean
#6
Stephen O Duke, Agnes M Rimando, Krishna N Reddy, James V Cizdziel, Nacer Bellaloui, David R Shaw, Martin M Williams, Jude E Maul
BACKGROUND: There has been controversy as to whether the glyphosate resistance gene and/or glyphosate applied to glyphosate-resistant (GR) soybean affect the content of cationic minerals (especially Mg, Mn, and Fe), yield and amino acid content of GR soybean. A two-year field study (2013 and 2014) examined these questions at sites in Mississippi, USA. RESULTS: There were no effects of glyphosate, the GR transgene, or field crop history (for a field with both no history of glyphosate use versus one with a long history of glyphosate use) on grain yield...
May 25, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28527498/electronic-health-record-transition-considerations
#7
REVIEW
Louis E Penrod
After an initial phase of electronic health record (EHR) solutions for both independent practices and larger health care organizations, we are now entering a period in which transitioning between EHRs is becoming more common. Many of the decisions and implementation processes for an EHR transition are similar to those encountered during the transition from paper records to an EHR. Detailed project planning and management are essential to keep the effort on track and within budget to a successful conclusion...
May 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28509679/the-impact-of-next-generation-sequencing-in-immunogenetics-current-status-and-future-directions
#8
Valia Bravo-Egana, Dimitri Monos
PURPOSE OF REVIEW: Next-generation sequencing (NGS) has now been established, and widely recognized, to be the preferred choice for human leukocyte antigen (HLA) typing. This transformation is based upon the many scientific, operational and economic benefits this technology affords. In this report, we review the major advantages, existing limitations and significant promise derived from adopting this technology in immunogenetics. RECENT FINDINGS: Significant benefits have emerged from the usage of NGS in a relatively short period, whereby we realize that this technology not only helps addressing the technical and operational problems we have had with the legacy methods for HLA typing, but equally important, it also allows for creative applications in stem cell and organ transplantation, new ways to investigate associations of the major histocompatibility complex (MHC) with many diseases and enhance our understanding regarding the MHC and non-MHC genomic interactions...
May 13, 2017: Current Opinion in Organ Transplantation
https://www.readbyqxmd.com/read/28493680/legacy-and-current-use-insecticides-in-agricultural-sediments-from-south-china-impact-of-application-pattern-on-occurrence-and-risk
#9
Yanli Wei, Huizhen Li, Junjie Zhang, Jingjing Xiong, Xiaoyi Yi, Jing You
Legacy and current-use insecticides were analyzed in sediments collected from a typical rice-planting region in South China. Total concentrations of insecticides varied from 1.63 to 775 ng g(-1) with mean and median values of 67.0 and 11.5 ng g(-1), respectively. Pyrethroids predominated pesticide composition (31.7%), followed by organophosphates (23.0%) and fiproles (20.8%). Sediment risk analysis showed that pyrethroids, fiproles, and abamectin posed significant risk to benthic invertebrates in one-third of sediments...
May 31, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28486928/patterns-of-divergence-in-fish-species-separated-by-the-isthmus-of-panama
#10
Christine E Thacker
BACKGROUND: The Pleistocene closure of Isthmus of Panama, separating the basins of the Eastern Pacific and the Caribbean Sea, created a unique natural experiment that reveals how marine faunas respond to environmental change. To explore how fishes have been affected by this tectonic event, I compare transisthmian patterns in phylogeny and morphology for geminate lineages in two families, Eleotridae (sleepers) and Apogonidae (cardinalfishes). RESULTS: Time-calibrated phylogenies for these families show different diversification patterns...
May 10, 2017: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/28464396/asymmetric-effects-of-cooler-and-warmer-winters-on-beech-phenology-last-beyond-spring
#11
Constant Signarbieux, Ester Toledano, Paula Sanginés de Carcer, Yongshuo H Fu, Rodolphe Schlaepfer, Alexandre Buttler, Yann Vitasse
In temperate trees, the timings of plant growth onset and cessation affect biogeochemical cycles, water and energy balance. Currently, phenological studies largely focus on specific phenophases and on their responses to warming. How differently spring phenology responds to the warming and cooling, and affects the subsequent phases, has not been yet investigated in trees. Here, we exposed saplings of Fagus sylvatica L. to warmer and cooler climate during the winter 2013-2014 by conducting a reciprocal transplant experiment between two elevations (1340 vs...
May 2, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28423918/expanding-the-palliative-care-domains-to-meet-the-needs-of-a-community-based-supportive-care-model
#12
Eric W Anderson, Monica S Frazer, Sandra E Schellinger
BACKGROUND: Whole person care is appropriate for seriously ill persons. The current framework of palliative care domains in the National Consensus Project (NCP) Guidelines for Quality Palliative Care offers an opportunity to reassess the domains of care delivered at home, earlier in the course of illness. OBJECTIVE: This qualitative study was used to test the applicability of a proposed, expanded set of domains. The results were used to inform a home-based, upstream model of supportive care for serious illness...
January 1, 2017: American Journal of Hospice & Palliative Care
https://www.readbyqxmd.com/read/28408134/norm-contaminated-area-identification-using-radionuclides-activity-concentration-pattern-in-a-soil-profile
#13
Bogusław Michalik
According to the requirements set by European BSS the exposure of humans and biota to ionizing radiation originating from natural radionuclides but under anthropogenically changed conditions should be managed within the same regulatory framework as other practices. Such situation creates the strong needs to have a reliable method to distinguish whether the particular case of natural radioactivity occurrence has resulted from human activity or it is pure natural phenomenon. In case of current activity of particular NORM industry there are no doubts however, in case of a legacy site, such question becomes crucial...
July 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28406389/the-informational-turn-in-food-politics-the-us-fda-s-nutrition-label-as-information-infrastructure
#14
Xaq Frohlich
This article traces the history of the US FDA regulation of nutrition labeling, identifying an 'informational turn' in the evolving politics of food, diet and health in America. Before nutrition labeling was introduced, regulators actively sought to segregate food markets from drug markets by largely prohibiting health information on food labels, believing such information would 'confuse' the ordinary food consumer. Nutrition labeling's emergence, first in the 1970s as consumer empowerment and then later in the 1990s as a solution to information overload, reflected the belief that it was better to manage markets indirectly through consumer information than directly through command-and-control regulatory architecture...
April 2017: Social Studies of Science
https://www.readbyqxmd.com/read/28398809/tagging-of-test-tubes-with-electronic-p-chips-for-use-in-biorepositories
#15
Wlodek Mandecki, Wesley M Kopacka, Ziye Qian, Von Ertwine, Katie Gedzberg, Maryann Gruda, David Reinhardt, Efrain Rodriguez
A system has been developed to electronically tag and track test tubes used in biorepositories. The system is based on a light-activated microtransponder, also known as a "p-Chip." One of the pressing problems with storing and retrieving biological samples at low temperatures is the difficulty of reliably reading the identification (ID) number that links each storage tube with the database containing sample details. Commonly used barcodes are not always reliable at low temperatures because of poor adhesion of the label to the test tube and problems with reading under conditions of frost and ice accumulation...
February 23, 2017: Biopreservation and Biobanking
https://www.readbyqxmd.com/read/28398195/mass-fainting-in-garment-factories-in-cambodia
#16
Maurice Eisenbruch
This paper reports an ethnographic study of mass fainting among garment factory workers in Cambodia. Research was undertaken in 2010-2015 in 48 factories in Phnom Penh and 8 provinces. Data were collected in Khmer using nonprobability sampling. In participant observation with monks, factory managers, health workers, and affected women, cultural understandings were explored. One or more episodes of mass fainting occurred at 34 factories, of which 9 were triggered by spirit possession. Informants viewed the causes in the domains of ill-health/toxins and supernatural activities...
April 2017: Transcultural Psychiatry
https://www.readbyqxmd.com/read/28377805/no-such-thing-as-mental-illness-critical-reflections-on-the-major-ideas-and-legacy-of-thomas-szasz
#17
EDITORIAL
Tony B Benning
Enfant terrible of psychiatry and widely known as one of its most indefatigable as well as iconoclastic critics, Thomas Szasz (1961-2012) had a prolific writing career that extended some 51 years beyond the publication of his first book, The Myth of Mental Illness, in 1961. This editorial identifies and critically discusses three major themes in Szasz's writings: his contention that there is no such thing as mental illness, his contention that individual responsibility is never compromised in those suffering from what is generally considered as mental illness, and his perennial interest in calling attention to the political nature of psychiatric diagnosis...
December 2016: BJPsych Bulletin
https://www.readbyqxmd.com/read/28373653/clinical-praxis-and-the-place-of-the-analyst-a-chilean-perspective
#18
Juan Flores
Since its inception, psychoanalytic theory has considered that, conceptually, it is impossible to maintain the division between the individual and society and that the constitution of one necessarily involves the other. Despite this clear legacy of Freudian thought, followed by most of the first and second generations of psychoanalysts, analytic clinical practice started to change almost exclusively into private practice by later generations of psychoanalysts. As a result, a space for information, data gathering, and theoretical production has been gradually configured that is structured in a slanted way...
April 2017: American Journal of Psychoanalysis
https://www.readbyqxmd.com/read/28372820/air-water-exchange-of-pahs-and-opahs-at-a-superfund-mega-site
#19
Lane G Tidwell, L Blair Paulik, Kim A Anderson
Chemical fate is a concern at environmentally contaminated sites, but characterizing that fate can be difficult. Identifying and quantifying the movement of chemicals at the air-water interface are important steps in characterizing chemical fate. Superfund sites are often suspected sources of air pollution due to legacy sediment and water contamination. A quantitative assessment of polycyclic aromatic hydrocarbons (PAHs) and oxygenated PAH (OPAHs) diffusive flux in a river system that contains a Superfund Mega-site, and passes through residential, urban and agricultural land, has not been reported before...
March 31, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28367483/the-pesticide-dieldrin-disrupts-proteins-related-to-oxidative-respiration-and-mitochondrial-stress-in-the-central-nervous-system
#20
Andrew M Cowie, Kathleena I Sarty, Angella Mercer, Jin Koh, Karen A Kidd, Christopher J Martyniuk
Quantitative proteins analysis was carried out in the hypothalamus of zebrafish following dietary exposure to the legacy pesticide dieldrin. Data were collected using iTRAQ labeling methodology and data were acquired using a hybrid quadrupole Orbitrap (Q Exactive) MS system (Thermo Fisher Scientific, Bremen, Germany). There were 3941 proteins identified in the hypothalamus of zebrafish, and these proteins comprised 23 unique expression patterns for proteins based on the three doses of dieldrin. There were 226 proteins that were regulated in one or more doses of dieldrin and 3715 proteins that were not affected...
April 2017: Data in Brief
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