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https://www.readbyqxmd.com/read/28072730/bortezomib-combined-with-lenalidomide-as-the-first-line-treatment-for-the-rare-synchronous-occurrence-of-multiple-myeloma-and-pulmonary-adenocarcinoma-a-case-report
#1
Wenli Zuo, Xinghu Zhu, Jingke Yang, Zhenyang Mei, Mei Deng, Quande Lin, Yongping Song, Qingsong Yin
BACKGROUND: Simultaneous multiple myeloma (MM) and pulmonary adenocarcinoma is a rare occurrence, and thus, treatment is a challenge. This study reports on 1 such case of MM with concurrent lung cancer, where an accurate diagnosis was made and the patient underwent treatment for both cancers. CASE SUMMARY: A 68-year-old man presented with 2 months of progressive lower back pain. Visualization with magnetic resonance imaging (MRI) revealed multiple collapsed vertebrae from T12 to S3, as well as an altered signal intensity at the T3 vertebra...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28067202/pulmonary-fibrosis-tissue-characterization-using-late-enhanced-mri-compared-with-unenhanced-anatomic-high-resolution-ct
#2
Lisa P Lavelle, Darragh Brady, Sinead McEvoy, David Murphy, Brian Gibney, Annika Gallagher, Marcus Butler, Fionnula Shortt, Marie McMullen, Aurelie Fabre, David A Lynch, Michael P Keane, Jonathan D Dodd
PURPOSE: We aimed to prospectively evaluate anatomic chest computed tomography (CT) with tissue characterization late gadolinium-enhanced magnetic resonance imaging (MRI) in the evaluation of pulmonary fibrosis (PF). METHODS: Twenty patients with idiopathic pulmonary fibrosis (IPF) and twelve control patients underwent late-enhanced MRI and high-resolution CT. Tissue characterization of PF was depicted using a segmented inversion-recovery turbo low-angle shot MRI sequence...
January 9, 2017: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/28051221/contribution-of-cardiac-magnetic-resonance-imaging-in-the-diagnosis-of-acute-coronary-syndrome-with-normal-coronary-angiography
#3
Rana Dahmani, Rim Ben Said, Younes Arous, Houaida Mahfoudhi, Chedia Chourabi, Mehdi Ghommidh, Badii Jedaida, Nizar Ben Mansour, Abdeddayem Haggui, Nadhem Hajlaoui, Dhaker Lahidheb, Wafa Fehri, Habib Haouala
Background - Acute coronary syndrome with high level of troponin is a common pattern for emergency consultation. In 10% of cases, coronary angiography concluded that there were no significant coronary lesions. The contribution of cardiac magnetic resonance imaging (MRI) in the etiological investigation is increasing in these conditions. Aim - We analyzed the diagnostic value of cardiac MRI in case of acute coronary syndromes with elevated troponin and normal coronary angiography. Methods - It's a retrospective analytical study including 31 patients presenting with acute coronary syndrome with positive troponins and normal coronary angiography...
June 2016: La Tunisie Médicale
https://www.readbyqxmd.com/read/28048364/we-fg-207a-01-introduction-to-dedicated-breast-ct-early-studies
#4
S Vedantham
: Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048140/mo-fg-campus-jep2-05-mri-guided-single-fraction-boost-delivery-on-individual-axillary-lymph-nodes
#5
T C F van Heijst, N Hoekstra, M E P Philippens, D Eschbach, J J W Lagendijk, H J G D van den Bongard, B van Asselen
PURPOSE: The Utrecht MRI-linac (MRL) design enables new MR-guided radiotherapy (RT) approaches. This is a feasibility study for a single-fraction high dose (boost) to individual lymph nodes (LNs) in breast-cancer patients, after breast-conserving surgery (BCS) and hypofractionated whole-breast irradiation (WBI) with conventional axillary RT (AxRT). METHODS: After written informed consent, 5 breast-cancer patients (cT1-3N0) were enrolled (NL500460.041.14 trial) and underwent 1...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047717/we-fg-207a-02-why-we-need-breast-ct-clinical-perspective
#6
A O'Connell
: Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047587/th-cd-207a-01-evaluation-of-lung-tumor-motion-management-strategy-with-dynamic-mri
#7
R Farah, S Park, S Shea, E Tryggestad, J Wong, R Hales, J Lee
PURPOSE: The purpose of this study is to develop a method to track and examine the correlation between the 3D motion of a lung tumor and an external surrogate with dynamic MRI. METHODS: Dynamic MRI was obtained from lung cancer patients. To examine the motion correlation between external surrogates and the tumor, we placed four fiducials on the patient's chest at different locations. We acquired a contiguous multi-slice 2D cine MRI (sagittal) to capture the lung and whole tumor, followed by a two-slice 2D cine MRI (sagittal) to simultaneously track the tumor and fiducials...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047520/we-fg-207a-05-dedicated-breast-ct-as-a-diagnostic-imaging-tool-physics-and-clinical-feasibility
#8
A Karellas
: Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047251/tu-h-campus-jep2-02-interobserver-variability-of-ct-pet-ct-and-mri-based-primary-tumor-delineation-for-lung-cancer
#9
K Karki, G Hugo, S Saraiya, N Jan, J Schuster, M Schutzer, L Fahrner, R Groves, J Ford, E Weiss
PURPOSE: Target delineation in lung cancer radiotherapy has, in general, large variability. MRI has so far not been investigated in detail for lung cancer delineation variability. The purpose of this study is to investigate delineation variability for lung tumors using MRI and compare it to CT alone and PET-CT based delineations. METHODS: Seven physicians delineated the primary tumor volumes of nine patients for the following scenarios: (1) CT only; (2) post-contrast T1-weighted MRI registered with diffusion-weighted MRI; and (3) PET-CT fusion images...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047068/we-fg-207a-03-low-dose-cone-beam-breast-ct-physics-and-technology-development
#10
J Boone
: Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046938/su-f-i-21-unfolding-of-aliased-dynamic-acquisitions-for-the-acceleration-of-breast-dynamic-contrast-enhanced-mri-dce-mri
#11
F Pineda, M Medved, X Fan, G Karczmar
PURPOSE: To determine the feasibility of increasing temporal resolution in breast DCE-MRI by reducing the field-of-view (FOV) and unfolding the aliased images using un-aliased subtraction images as guides. METHODS: Experience with an 'ultrafast' protocol for breast DCE-MRI (6-10s acquisitions) showed that the number of significantly enhancing voxels was very low (<7% of the FOV) in the first 30-45s after contrast injection. The sparse enhancement in these images suggests that if the FOV is reduced in the phase-encoding direction (reducing acquisition time) and aliasing occurs, the likelihood of two significantly-enhancing voxels overlapping in the aliased image is relatively low...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046408/we-fg-207a-04-performance-characteristics-of-photon-counting-breast-ct
#12
W Kalender
: Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046298/th-cd-207b-11-multi-vendor-phantom-study-of-ct-lung-density-metrics-is-a-reproducibility-of-less-than-1-hu-achievable
#13
H Chen-Mayer, P Judy, S Fain, B Hoppel, D Lynch, M Fuld
PURPOSE: To standardize the calibration procedures of CT lung density measurements using low-density reference foams in a phantom, and to demonstrate a reproducibility of less than 1 HU for lung equivalent foam densities measured across CT vendor platforms and protocols. METHODS: A phantom study was conducted on CT scanner models from 4 vendors at 100, 120, and 135/140 kVp and 1.5, 3, and 6 mGy dose settings, using a lung density phantom containing air, water, and 3 reference foams (indirectly calibrated) with discrete densities simulating a 5-cm slice of the human chest...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046291/we-fg-207a-00-advances-in-dedicated-breast-ct
#14
Srinivasan Vedantham, Sabee Molloi
: Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28040479/chest-imaging-in-cystic-fibrosis-studies-what-counts-and-can-be-counted
#15
REVIEW
Rhonda Szczesniak, Lidija Turkovic, Eleni-Rosalina Andrinopoulou, Harm A W M Tiddens
BACKGROUND: The dawn of precision medicine and CFTR modulators require more detailed assessment of lung structure in cystic fibrosis (CF) clinical studies. Various imaging markers have emerged and are measurable, but clarity is needed to identify what markers should count for clinical studies. High-resolution chest computed tomography (CT) scoring has yielded sensitive markers for the study of CF disease progression. Once completed, CT scores from ongoing randomized controlled trials can be used to examine relationships between imaging endpoints and therapeutic effectiveness...
December 28, 2016: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
https://www.readbyqxmd.com/read/28032913/correction-of-hysteretic-respiratory-motion-in-spect-myocardial-perfusion-imaging-simulation-and-patient-studies
#16
Paul K R Dasari, Arda Könik, P Hendrik Pretorius, Karen L Johnson, William P Segars, Mohammed S Shazeeb, Michael A King
PURPOSE: Amplitude based respiratory gating is known to capture the extent of respiratory motion (RM) accurately but results in residual motion in the presence of respiratory hysteresis. In our previous study, we proposed and developed a novel approach to account for respiratory hysteresis by applying the Bouc-Wen (BW) model of hysteresis to external surrogate signals of anterior / posterior motion of the abdomen and chest with respiration. In this work using simulated and clinical SPECT myocardial perfusion imaging (MPI) studies, we investigate the effects of respiratory hysteresis and evaluate the benefit of correcting it using the proposed BW model in comparison with the abdomen signal typically employed clinically...
December 29, 2016: Medical Physics
https://www.readbyqxmd.com/read/28028503/cardiac-hydatid-cyst-a-case-report
#17
Esfandiar Shojaei, Zeynab Yassin, Omid Rezahosseini
Hydatid disease commonly involves liver but in rare cases, it can involve cardiac structures. A 75-yr-old farmer from Parsabad-Moghan, northwestern Iran was presented to the Emergency Room of Tehran Imam Khomeini Hospital, Tehran, Iran with dyspnea and without chest pain in 2014. A lesion compatible with hydatid cyst was found in echocardiography and confirmed by serology and MRI. Surgical treatment was done but the patient was died in recovery room because of cardiac arrhythmia. In endemic areas, hydatid cyst should be considered in differential diagnosis of heterogeneous echogenic lesions even if the serologic tests are negative...
November 2016: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28027747/imaging-findings-of-kaposiform-hemangioendothelioma-in-children
#18
Young Jin Ryu, Young Hun Choi, Jung-Eun Cheon, Woo Sun Kim, In-One Kim, Ji Eun Park, Yu Jin Kim
PURPOSE: Kaposiform hemangioendothelioma (KHE) is a rare, aggressive vascular tumor that typically occurs during infancy or early childhood. Though several case reports have discussed the imaging findings of KHE, larger comprehensive studies are lacking. The purpose of this study was to evaluate the imaging findings of KHE in children. MATERIALS AND METHODS: A total of twelve cases of pathologically proven KHE were collected by searching our institution's pathology database for children diagnosed between January 2004 and April 2016 (6 male, 6 female; median age: 3 months; age range 7days - 18 years)...
January 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28027517/-18-f-fdg-pet-ct-surveillance-for-the-detection-of-recurrence-in-patients-with-head-and-neck-cancer
#19
Shin-Ae Kim, Jong-Lyel Roh, Jae Seung Kim, Jeong Hyun Lee, Sang Hoon Lee, Seung-Ho Choi, Soon Yuhl Nam, Sang Yoon Kim
BACKGROUND: Posttreatment detection of recurrence may lead to salvage treatment and prognostic prediction in patients with head and neck squamous cell carcinoma (HNSCC). We evaluated the diagnostic and prognostic values of (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography (PET)/computed tomography (CT) after definitive treatment of HNSCC. METHODS: This prospective study included 278 consecutive patients who underwent curative surgery (n = 143, 51...
December 24, 2016: European Journal of Cancer
https://www.readbyqxmd.com/read/28025408/a-case-of-anti-aquapolin-4-antibody-positive-myelitis-with-hyperhidrosis-following-herpes-zoster
#20
Machiko Suda, Michiko Tsutsumiuchi, Yoshikazu Uesaka, Nobukazu Hayashi
We report an acute myelitis in a 53-year-old woman that occurred in 7 days after the diagnosis of Th5-6 herpes zoster. Clinical examination revealed hyperhidrosis of left side of her face, neck, arm and upper chest. She also had muscle weakness of her left leg and sensory impairment for light touch and temperature in her chest and legs. Spinal cord MRI demonstrated a longitudinal T2-hyperintense lesion extending from Th1 to 7. In the axial imaging, the lesion dominantly located in the left side gray matter...
December 23, 2016: Rinshō Shinkeigaku, Clinical Neurology
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