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https://www.readbyqxmd.com/read/29766512/structured-radiology-reporting-on-an-institutional-level-benefit-or-new-administrative-burden
#1
REVIEW
Daniel Pinto Dos Santos, Elmar Kotter
Significant technical advances have been made in radiology since the first discovery of X-rays. Diagnostic techniques have become more and more complex, workflows have been digitized, and data production has increased exponentially. However, the radiology report as the main method for communicating examination results has largely remained unchanged. Growing evidence supports that more structured radiology reports offer various benefits over conventional narrative reports. Various efforts have been made to further develop and promote structured reporting...
May 16, 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29765762/tris-2-2-6-6-tetra-methyl-8-tri-methyl-sil-yl-benzo-1-2-d-4-5-d-bis-1-3-di-thiol-4-yl-methanol-diethyl-ether-monosolvate
#2
Nico Fleck, Gregor Schnakenburg, Alexander C Filippou, Olav Schiemann
The title compound, a tri-aryl-methanol, C46 H64 OS12 Si3 1 , was synthesized via li-thia-tion of tris-2,2,6,6-tetra-methyl-benzo[1,2- d ;4,5- d ']bis-[1,3]di-thiol-4-yl-methanol, 2 , and electrophilic quenching with tri-methyl-silyl chloride. The current crystal structure reveals information about the reactivity of this compound and compares well with the structure reported for the unsubstituted parent compound 2 [Driesschaert et al. (2012 ▸). Eur. J. Org. Chem. 33 , 6517-6525]. The title compound 1 forms mol-ecular propellers and crystallizes in P [Formula: see text], featuring an unusually long Si-Car bond of 1...
April 1, 2018: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/29753407/structured-head-and-neck-ct-angiography-reporting-reduces-resident-revision-rates
#3
Tucker F Johnson, Waleed Brinjikji, Derrick A Doolittle, Alex A Nagelschneider, Brian T Welch, Amy L Kotsenas
PURPOSE: This resident-driven quality improvement project was undertaken to assess the effectiveness of structured reporting to reduce revision rates for afterhours reports dictated by residents. METHODS: The first part of the study assessed baseline revision rates for head and neck CT angiography (CTA) examinations dictated by residents during afterhours call. A structured report was subsequently created based on templates on the RSNA informatics reporting website and critical findings that should be assessed for on all CTA examinations...
April 12, 2018: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/29752835/documentation-of-psychotropic-prn-medication-administration-an-evaluation-of-electronic-health-records-compared-with-paper-charts-and-verbal-reports
#4
Krystle Martin, Elke Ham, Zoe Hilton
AIMS AND OBJECTIVES: To describe the documentation of pro re nata (PRN) medication for anxiety, and to compare documentation at two hospitals providing similar psychiatric services, one that used paper charts and another that used an electronic health record (EHR). We also assessed congruence between nursing documentation and verbal reports from staff about the PRN administration process. BACKGROUND: The ability to accurately document patients' symptoms and the care given is considered a core competency of the nursing profession (Wilkinson, 2007); however, researchers have found poor concordance between nursing notes and verbal reports or observations of events (e...
May 12, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29745767/a-proof-of-concept-for-epidemiological-research-using-structured-reporting-with-pulmonary-embolism-as-a-use-case
#5
Pinto Dos Santos Daniel, Scheibl Sonja, Arnhold Gordon, Maehringer-Kunz Aline, Düber Christoph, Mildenberger Peter, Kloeckner Roman
OBJECTIVE: This paper studies the possibilities of an integrated IT-based workflow for epidemiological research in pulmonary embolism using freely available tools and structured reporting. METHODS: We included a total of 521 consecutive cases which had been referred to the radiology department for computed tomography pulmonary angiography (CTPA) with suspected pulmonary embolism (PE). Free-text reports were transformed into structured reports using a freely available IHE-MRRT-compliant reporting platform...
May 10, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29739407/work-shadowing-in-dental-teaching-practices-evaluation-results-of-a-collaborative-study-between-university-and-general-dental-practices
#6
Stefan J Heitkamp, Stefan Rüttermann, Susanne Gerhardt-Szép
BACKGROUND: The aim of this study was to investigate the acceptance and assessment of work shadowing carried out by students and dentists in dental practices. Furthermore, the extent to which students perceive an improvement in their specialised, communication and social competencies, was to be examined. METHODS: 61 dental students in their clinical semesters at a German university participated in work shadowing placements at 27 different general dental practices...
May 8, 2018: BMC Medical Education
https://www.readbyqxmd.com/read/29729037/using-focused-ethnography-to-explore-and-describe-the-process-of-nurses-shift-reports-in-a-psychiatric-intensive-care-unit
#7
Martin Salzmann-Erikson
AIMS AND OBJECTIVES: To explore and describe the cultural routine of shift reports among nursing staff in a psychiatric intensive care unit, and further to develop a taxonomic, thematic and theoretical understanding of the process. BACKGROUND: Lack of communication among healthcare staff is associated with risks for medical errors. Thus, handovers and shift reports are an essential and integral routine among nurses in order to pass on information about the patients' health status...
May 5, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29728815/structured-reporting-of-pelvic-mri-leads-to-better-treatment-planning-of-uterine-leiomyomas
#8
Evis Sala, Susan Freeman
No abstract text is available yet for this article.
May 4, 2018: European Radiology
https://www.readbyqxmd.com/read/29726867/use-multiscale-simulation-to-explore-the-effects-of-the-homodimerizations-between-different-conformation-states-on-the-activation-and-allosteric-pathway-for-the-%C3%AE-opioid-receptor
#9
Xi Zhang, Yuan Yuan, Longrong Wang, Yanzhi Guo, Menglong Li, Chuan Li, Xuemei Pu
Recently, oligomers of G-protein coupled receptors (GPCRs) have been an important topic in the GPCR fields. However, knowledge about their structures and activation mechanisms is very limited due to the absence of crystal structures reported. In this work, we used multiscale simulations to study the effects of homodimerization between different conformation states on their activation, dynamic behaviors, and allosteric communication pathways for μ-OR. The results indicated that the dimerization of one inactive monomer with either one inactive monomer or one active one could enhance its constitutive activation...
May 4, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29720635/hyperexpandable-self-healing-macromolecular-crystals-with-integrated-polymer-networks
#10
Ling Zhang, Jake B Bailey, Rohit H Subramanian, F Akif Tezcan
The formation of condensed matter typically involves a trade-off between structural order and flexibility. As the extent and directionality of interactions between atomic or molecular components increase, materials generally become more ordered but less compliant, and vice versa. Nevertheless, high levels of structural order and flexibility are not necessarily mutually exclusive; there are many biological (such as microtubules1,2 , flagella 3 , viruses4,5 ) and synthetic assemblies (for example, dynamic molecular crystals6-9 and frameworks10-13 ) that can undergo considerable structural transformations without losing their crystalline order and that have remarkable mechanical properties8,14,15 that are useful in diverse applications, such as selective sorption 16 , separation 17 , sensing 18 and mechanoactuation 19 ...
May 2018: Nature
https://www.readbyqxmd.com/read/29720399/crystal-structure-of-the-human-4-1bb-4-1bbl-complex
#11
Ryan N Gilbreth, Vaheh Y Oganesyan, Hamza Amdouni, Shabazz Novarra, Luba Grinberg, Arnita Barnes, Manuel Baca
4-1BBL is a member of the TNF superfamily and is the ligand for the TNFRsuperfamily receptor, 4-1BB. 4-1BB plays an immunomodulatory role in T cells and NK cells and agonists of this receptor have garnered strong attention as potentialimmunotherapy agents. Broadly speaking, the structural features of TNF superfamilymembers, their receptors and ligand/receptor complexes are similar. However, apublished crystal structure of human 4-1BBL suggests that it may be unique in thisregard, exhibiting a three-bladed propeller-like trimer assembly that is distinctly different from that observed in other family members...
May 2, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29697362/an-integrated-clinical-and-genomic-information-system-for-cancer-precision-medicine
#12
Yeongjun Jang, Taekjin Choi, Jongho Kim, Jisub Park, Jihae Seo, Sangok Kim, Yeajee Kwon, Seungjae Lee, Sanghyuk Lee
BACKGROUND: Increasing affordability of next-generation sequencing (NGS) has created an opportunity for realizing genomically-informed personalized cancer therapy as a path to precision oncology. However, the complex nature of genomic information presents a huge challenge for clinicians in interpreting the patient's genomic alterations and selecting the optimum approved or investigational therapy. An elaborate and practical information system is urgently needed to support clinical decision as well as to test clinical hypotheses quickly...
April 20, 2018: BMC Medical Genomics
https://www.readbyqxmd.com/read/29679214/improvement-of-radiology-reporting-in-a-clinical-cancer-network-impact-of-an-optimised-multidisciplinary-workflow
#13
A W Olthof, J Borstlap, W W Roeloffzen, P M C Callenbach, P M A van Ooijen
PURPOSE: To assess the effectiveness of implementing a quality improvement project in a clinical cancer network directed at the response assessment of oncology patients according to RECIST-criteria. METHODS: Requests and reports of computed tomography (CT) studies from before (n = 103) and after (n = 112) implementation of interventions were compared. The interventions consisted of: a multidisciplinary working agreement with a clearly described workflow; subspecialisation of radiologists; adaptation of the Picture Archiving and Communication System (PACS); structured reporting...
April 20, 2018: European Radiology
https://www.readbyqxmd.com/read/29676356/current-practice-in-handling-and-reporting-needle-biopsies-a-hospital-based-survey
#14
Paritosh Garg, Priya Pathak, Rachna Goyal, Vinod K Arora, Navjeevan Singh
Context: Core-needle biopsy (CNB) is a minimally invasive screening and diagnostic tool which provides intact tissue fragments for histopathological examination. Aims: This study was conducted to review the current practices of handling and reporting CNBs performed for core-needle biopsies from four organ systems which are frequently encountered in our institution. These include breast, prostate, soft tissues, and lymph nodes. Settings and Design: This was a retrospective study conducted at a tertiary care hospital...
April 2018: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/29627139/structured-reporting-of-ct-angiography-runoff-examinations-of-the-lower-extremities
#15
Bastian O Sabel, Jessica L Plum, Michael Czihal, Christian Lottspeich, Frank Schönleben, Gabor Gäbel, Regina Schinner, Franziska Schoeppe, Felix G Meinel
OBJECTIVES: The aim was to evaluate the effect of structured reporting of computed tomography angiography (CTA) runoff studies on clarity, completeness, clinical relevance, usefulness of the radiology reports, further testing, and therapy in patients with known or suspected peripheral arterial disease. METHODS: Conventional reports (CRs) and structured reports (SRs) were generated for 52 patients who had been examined with a CTA runoff examination of the lower extremities...
April 4, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29621499/new-insight-into-the-allosteric-effect-of-l-tyrosine-on-mushroom-tyrosinase-during-l-dopa-production
#16
Sorour Hassani, Behzad Gharechaei, Somayeh Nikfard, Mostafa Fazli, Nematollah Gheibi, Renaud Hardré, Raymond L Legge, Kamahldin Haghbeen
Kinetics studies of L-tyrosine (LTy) ortho-hydroxylation by mushroom tyrosinase (MT) confirmed that MT was severely, but not completely, inhibited at higher concentrations of LTy. Despite the availability of the crystal structure reports, no allosteric site has been identified on MT. To examine the assumption that a non-specific binding site works as a regulatory site, docking simulations were run for the second molecule of L-tyrosine (LTy2 ) on the complexes of the first L-tyrosine molecule (LTy1 ) with the heavy chain (H) of MT (LTy1 /HMT) and its dimer with the light chain (Ty1 /LHMT)...
April 2, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29616496/how-to-use-the-kaiser-score-as-a-clinical-decision-rule-for-diagnosis-in-multiparametric-breast-mri-a-pictorial-essay
#17
REVIEW
Matthias Dietzel, Pascal A T Baltzer
Due to its superior sensitivity, breast MRI (bMRI) has been established as an important additional diagnostic tool in the breast clinic and is used for screening in patients with an elevated risk for breast cancer. Breast MRI, however, is a complex tool, providing multiple images containing several contrasts. Thus, reading bMRI requires a structured approach. A lack of structure will increase the rate of false-positive findings and sacrifice most of the advantages of bMRI as additional work-up will be required...
April 3, 2018: Insights Into Imaging
https://www.readbyqxmd.com/read/29605454/how-to-integrate-quantitative-information-into-imaging-reports-for-oncologic-patients
#18
L Martí-Bonmatí, E Ruiz-Martínez, A Ten, A Alberich-Bayarri
Nowadays, the images and information generated in imaging tests, as well as the reports that are issued, are digital and represent a reliable source of data. Reports can be classified according to their content and to the type of information they include into three main types: organized (free text in natural language), predefined (with templates and guidelines elaborated with previously determined natural language like that used in BI-RADS and PI-RADS), or structured (with drop-down menus displaying questions with various possible answers that have been agreed on with the rest of the multidisciplinary team, which use standardized lexicons and are structured in the form of a database with data that can be traced and exploited with statistical tools and data mining)...
March 28, 2018: Radiología
https://www.readbyqxmd.com/read/29600475/structured-reporting-adds-clinical-value-in-primary-ct-staging-of-diffuse-large-b-cell-lymphoma
#19
Franziska Schoeppe, Wieland H Sommer, Dominik Nörenberg, Mareike Verbeek, Christian Bogner, C Benedikt Westphalen, Martin Dreyling, Ernst J Rummeny, Alexander A Fingerle
OBJECTIVES: To evaluate whether template-based structured reports (SRs) add clinical value to primary CT staging in patients with diffuse large B-cell lymphoma (DLBCL) compared to free-text reports (FTRs). METHODS: In this two-centre study SRs and FTRs were acquired for 16 CT examinations. Thirty-two reports were independently scored by four haematologists using a questionnaire addressing completeness of information, structure, guidance for patient management and overall quality...
March 29, 2018: European Radiology
https://www.readbyqxmd.com/read/29589903/changes-in-protein-dynamics-in-escherichia-coli-sufs-reveal-a-possible-conserved-regulatory-mechanism-in-type-ii-cysteine-desulfurase-systems
#20
Dokyong Kim, Harsimran Singh, Yuyuan Dai, Guangchao Dong, Laura S Busenlehner, Franklin Wayne Outten, Patrick A Frantom
In the Suf Fe-S cluster assembly pathway, the activity of the cysteine desulfurase, SufS, is regulated by interactions with the accessory sulfotransferase protein, SufE. SufE has been shown to stimulate SufS activity, likely through inducing conformational changes in the SufS active site that promote the desulfurase step and by acting as an efficient persulfide acceptor in the transpersulfuration step. Previous results point toward an additional level of regulation through a 'half-sites' mechanism that affects the stoichiometry and affinity for SufE as the dimeric SufS shifts between desulfurase and transpersulfuration activities...
March 28, 2018: Biochemistry
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