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https://www.readbyqxmd.com/read/28736924/evaluation-of-spiral-acquisition-variants-for-functional-imaging-of-human-superior-colliculus-at-3t-field-strength
#1
Vimal Singh, Josef Pfeuffer, Tiejun Zhao, David Ress
PURPOSE: High-resolution functional magnetic resonance imaging of human subcortical brain structures is challenging because of their deep location in the cranium, and their comparatively weak blood oxygen level dependent responses to strong stimuli. Magnetic resonance imaging data for subcortical brain regions exhibit both low signal-to-noise ratio and low functional contrast-to-noise ratio. To overcome these challenges, this work evaluates the use of dual-echo spiral variants that combine outward and inward trajectories...
July 24, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28736704/visualization-of-photoacoustic-images-in-a-limited-view-measuring-system-using-eigenvalues-of-a-photoacoustic-transmission-matrix
#2
Hiroshi Abe, Tsuyoshi Shiina
Photoacoustic imaging is a unique imaging method that involves extracting information from points at different depths, an advantage of ultrasound imaging, while maintaining functional information, a key feature of conventional photo imaging. This makes it easy to add functional images to ultrasound images by adding a laser pulse source to the conventional ultrasound imaging device and detecting a photo-ultrasound signal via a conventional ultrasound probe. One challenge when using normal one-dimensional (1D) probes and generating photoacoustic images is the limited-view problem, in which artefacts are observed due to the positions of the ultrasound transducers...
December 2017: Photoacoustics
https://www.readbyqxmd.com/read/28736307/local-striatal-reward-signals-can-be-predicted-from-corticostriatal-connectivity
#3
Peter Smittenaar, Zeb Kurth-Nelson, Siawoosh Mohammadi, Nikolaus Weiskopf, Raymond J Dolan
A defining feature of the basal ganglia is their anatomical organization into multiple cortico-striatal loops. A central tenet of this architecture is the idea that local striatal function is determined by its precise connectivity with cortex, creating a functional topography that is mirrored within cortex and striatum. Here we formally test this idea using both human anatomical and functional imaging, specifically asking whether within striatal subregions one can predict between-voxel differences in functional signals based on between-voxel differences in corticostriatal connectivity...
July 20, 2017: NeuroImage
https://www.readbyqxmd.com/read/28728155/morphological-and-functional-imaging-for-detecting-and-assessing-the-resectability-of-neuroendocrine-liver-metastases
#4
Maxime Ronot, Ashley K Clift, Richard P Baum, Aviral Singh, Harshad R Kulkarni, Andrea Frilling, Valérie Vilgrain
No abstract text is available yet for this article.
July 21, 2017: Neuroendocrinology
https://www.readbyqxmd.com/read/28720413/multiparametric-magnetic-resonance-imaging-of-the-prostate-for-tumour-detection-and-local-staging-imaging-in-1-5t-and-histopathologic-correlation
#5
Dimitra Loggitsi, Anastasios Gyftopoulos, Nikolaos Economopoulos, Aikaterini Apostolaki, Theodoros Kalogeropoulos, Anastasios Thanos, Efthimia Alexopoulou, Nikolaos L Kelekis
PURPOSE: The study sought to prospectively evaluate which technique among T2-weighted images, dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI), diffusion-weighted (DW) MRI, or a combination of the 2, is best suited for prostate cancer detection and local staging. METHODS: Twenty-seven consecutive patients with biopsy-proven adenocarcinoma of the prostate underwent MRI on a 1.5T scanner with a surface phased-array coil prior radical prostatectomy...
July 15, 2017: Canadian Association of Radiologists Journal, Journal L'Association Canadienne des Radiologistes
https://www.readbyqxmd.com/read/28718164/advances-in-imaging-in-prostate-and-bladder-cancer
#6
REVIEW
Abhishek Srivastava, Laura M Douglass, Victoria Chernyak, Kara L Watts
Recent advancements in urologic imaging techniques aim to improve the initial detection of urologic malignancies and subsequent recurrence and to more accurately stage disease. This allows the urologist to make better informed treatment decisions. In particular, exciting advances in the imaging of prostate cancer and bladder cancer have recently emerged including the use of dynamic, functional imaging with MRI and PET. In this review, we will explore these imaging modalities, in addition to new sonography techniques and CT, and how they hope to improve the diagnosis and management of prostate and bladder cancer...
September 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28717412/diffusion-magnetic-resonance-imaging-a-molecular-imaging-tool-caught-between-hope-hype-and-the-real-world-of-personalized-oncology
#7
REVIEW
Abhishek Mahajan, Sneha S Deshpande, Meenakshi H Thakur
"Personalized oncology" is a multi-disciplinary science, which requires inputs from various streams for optimal patient management. Humongous progress in the treatment modalities available and the increasing need to provide functional information in addition to the morphological data; has led to leaping progress in the field of imaging. Magnetic resonance imaging has undergone tremendous progress with various newer MR techniques providing vital functional information and is becoming the cornerstone of "radiomics/radiogenomics"...
June 28, 2017: World Journal of Radiology
https://www.readbyqxmd.com/read/28716235/psychosis-in-parkinson-s-disease-from-the-soft-signs-to-the-hard-science
#8
REVIEW
Abhishek Lenka, Priyantha Herath, Rita Christopher, Pramod Kumar Pal
Patients with Parkinson's disease (PD) may develop a wide spectrum of non-motor symptoms during the course of illness. Psychosis is one such commonly observed non-motor symptoms of PD. Although several studies based on neuroimaging, genetics, retinal imaging, and neuropsychological evaluations have explored the pathogenesis of psychosis in PD; exact neural correlates are yet to be understood. Identification of factors related to psychosis in PD is important, as psychosis has been reported to be associated with higher rates of mortality, caregiver distress, and nursing home placements...
August 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28715675/resting-state-brain-networks-in-patients-with-parkinson-s-disease-and-impulse-control-disorders
#9
Alessandro Tessitore, Gabriella Santangelo, Rosa De Micco, Alfonso Giordano, Simona Raimo, Marianna Amboni, Fabrizio Esposito, Paolo Barone, Gioacchino Tedeschi, Carmine Vitale
INTRODUCTION: To investigate intrinsic neural networks connectivity changes in Parkinson's disease (PD) patients with and without impulse control disorders (ICD). METHODS: Fifteen patients with PD with ICD (ICD+), 15 patients with PD without ICD (ICD-) and 24 age and sex-matched healthy controls (HC) were enrolled in the study. To identify patients with and without ICD and/or punding, we used the Minnesota Impulsive Disorders Interview (MIDI) and a clinical interview based on diagnostic criteria for each symptom...
June 24, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28715124/chemical-imaging-of-fresh-vascular-smooth-muscle-cell-response-by-epi-detected-stimulated-raman-scattering
#10
Delong Zhang, Wei Chen, Huan Chen, Han-Qing Yu, Ghassan Kassab, Ji-Xin Cheng
An understanding of deformation of cardiovascular tissue under hemodynamic load is crucial for understanding the health and disease of blood vessels. In the present work, an epi-detected stimulated Raman scattering (epi-SRS) imaging platform was designed for in situ functional imaging of vascular smooth muscle cells (VMSCs) in fresh coronary arteries. For the first time, the pressure-induced morphological deformation of fresh VSMCs was imaged with no fixation and in a label free manner. The relation between the loading pressure and the morphological parameters, including angle and length of the VSMCs, were apparent...
July 17, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/28712282/deformable-image-registration-in-radiation-therapy
#11
REVIEW
Seungjong Oh, Siyong Kim
The number of imaging data sets has significantly increased during radiation treatment after introducing a diverse range of advanced techniques into the field of radiation oncology. As a consequence, there have been many studies proposing meaningful applications of imaging data set use. These applications commonly require a method to align the data sets at a reference. Deformable image registration (DIR) is a process which satisfies this requirement by locally registering image data sets into a reference image set...
June 2017: Radiation Oncology Journal
https://www.readbyqxmd.com/read/28711954/imaging-in-children-with-unilateral-ureteropelvic-junction-obstruction-time-to-reduce-investigations
#12
Nadin Abadir, Maria Schmidt, Guido F Laube, Marcus Weitz
The objective of the study was the development of an abridged risk-stratified imaging algorithm for the management of children with unilateral ureteropelvic junction obstruction (UPJO). Data on timing, frequency and duration of diagnostic imaging in children with unilateral UPJO was extracted retrospectively. Based on these findings, an abridged imaging algorithm was developed without changing the intended management by the clinicians and the outcome of the individual patient. The potential reduction of imaging studies was analysed and stratified by risk and management groups...
July 15, 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/28707737/-18-f-sodium-fluoride-positron-emission-tomography-of-the-equine-distal-limb-exploratory-study-in-three-horses
#13
M Spriet, P Espinosa, A Z Kyme, K L Phillips, S A Katzman, L D Galuppo, P Stepanov, D Beylin
BACKGROUND: Positron Emission Tomography (PET) is a cross-sectional, functional imaging modality that has recently become available to the horse. The use of (18) F-sodium fluoride ((18) F-NaF), a PET bone tracer, has never been reported in this species. OBJECTIVES: To assess the feasibility of (18) F-NaF PET in the equine distal limb and explore possible applications in the horse in comparison with other imaging modalities. STUDY DESIGN: Exploratory descriptive study involving three research horses...
July 14, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/28706270/comprehensive-multi-dimensional-mri-for-the-simultaneous-assessment-of-cardiopulmonary-anatomy-and-physiology
#14
Joseph Y Cheng, Tao Zhang, Marcus T Alley, Martin Uecker, Michael Lustig, John M Pauly, Shreyas S Vasanawala
Diagnostic testing often assesses the cardiovascular or respiratory systems in isolation, ignoring the major pathophysiologic interactions between the systems in many diseases. When both systems are assessed currently, multiple modalities are utilized in costly fashion with burdensome logistics and decreased accessibility. Thus, we have developed a new acquisition and reconstruction paradigm using the flexibility of MRI to enable a comprehensive exam from a single 5-15 min scan. We constructed a compressive-sensing approach to pseudo-randomly acquire highly subsampled, multi-dimensionally-encoded and time-stamped data from which we reconstruct volumetric cardiac and respiratory motion phases, contrast-agent dynamics, and blood flow velocity fields...
July 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28699016/position-related-renal-perfusion-disturbances-as-a-possible-underestimated-mechanism-in-patients-with-resistant-hypertension-a-case-vignette
#15
Jan Schiefer, Holger Amthauer, Philipp Genseke, Peter R Mertens, Christos Chatzikyrkou
PURPOSE: In patients with resistant hypertension and large blood pressure fluctuations, the role of orthostatic hypertension, associated with position-dependent renal perfusion disturbances, has not been investigated in detail yet. METHODS: In this regard, four patients from our outpatient clinic were investigated by the use of 24-h ambulatory blood pressure monitoring (ABPM), active standing test, renal duplex sonography and Tc99m-mercaptoacetyltriglycine [MAG3] renal scintigraphy in supine and upright position...
July 11, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28697192/a-prototype-pet-spect-x-rays-scanner-dedicated-for-whole-body-small-animal-studies
#16
Maritina Rouchota, Maria Georgiou, Eleftherios Fysikopoulos, Eirini Fragogeorgi, Konstantinos Mikropoulos, Panagiotis Papadimitroulas, George Kagadis, George Loudos
OBJECTIVE: To present a prototype tri-modal imaging system, consisting of a single photon emission computed tomography (SPET), a positron emission tomography (PET), and a computed tomography (CT) subsystem, evaluated in planar mode. MATERIALS AND METHODS: The subsystems are mounted on a rotating gantry, so as to be able to allow tomographic imaging in the future. The system, designed and constructed by our group, allows whole body mouse imaging of competent performance and is currently, to the best of our knowledge, unequaled in a national and regional level...
July 12, 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28697186/whiplash-syndrome-a-disorder-of-the-brain
#17
EDITORIAL
Jennifer Biendara, Andreas Otte
In the past two decades much has been published on whiplash injury, yet both the confusion regarding the condition, and the medicolegal discussion about it have increased. In this paper, functional imaging research results are summarized using MRIcroGL 3D visualization software and assembled in an image comprising regions of cerebral activation and deactivation.
July 12, 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28696028/pretransplant-functional-imaging-and-outcome-in-pediatric-patients-with-relapsed-refractory-hodgkin-lymphoma-undergoing-autologous-transplantation
#18
Nmazuo W Ozuah, Hisham M Dahmoush, Frederick D Grant, Leslie E Lehmann, Ann S LaCasce, Amy L Billett, Steven P Margossian
BACKGROUND: Pretransplant functional imaging (FI), particularly a negative positron emission tomography (PET), is a strong predictor of outcome in adults with relapsed or refractory Hodgkin lymphoma (HL), but data in pediatrics are limited. METHODS: The medical records of 49 consecutive pediatric patients, who received autologous transplant at a single institution, were retrospectively analyzed. All patients had either gallium or PET scan before transplant and were conditioned with carmustine, etoposide, cytarabine, and melphalan (BEAM)...
July 11, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28694303/single-molecule-fluorescence-microscopy-review-shedding-new-light-on-old-problems
#19
Sviatlana Shashkova, Mark C Leake
Fluorescence microscopy is an invaluable tool in the biosciences, a genuine workhorse technique offering exceptional contrast in conjunction with high specificity of labelling with relatively minimal perturbation to biological samples compared to many competing biophysical techniques. Improvements in detector and dye technologies coupled to advances in image analysis methods have fuelled recent development towards single-molecule fluorescence microscopy, which can utilise light microscopy tools to enable the faithful detection and analysis of single fluorescent molecules used as reporter tags in biological samples...
July 10, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/28690357/federating-heterogeneous-datasets-to-enhance-data-sharing-and-experiment-reproducibility
#20
Juan C Prieto, Beatriz Paniagua, Marilia S Yatabe, Antonio C O Ruellas, Liana Fattori, Luciana Muniz, Martin Styner, Lucia Cevidanes
Recent studies have demonstrated the difficulties to replicate scientific findings and/or experiments published in past.(1) The effects seen in the replicated experiments were smaller than previously reported. Some of the explanations for these findings include the complexity of the experimental design and the pressure on researches to report positive findings. The International Committee of Medical Journal Editors (ICMJE) suggests that every study considered for publication must submit a plan to share the de-identified patient data no later than 6 months after publication...
February 11, 2017: Proceedings of SPIE
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