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https://www.readbyqxmd.com/read/29151262/the-founding-fathers-of-the-international-neuroendocrine-society-ins
#1
EDITORIAL
Víctor D Ramirez
It seems appropriate in this Special Issue of Journal of Neuroendocrinology, which marks the new Pan American Neuroendocrine Society (PANS), to recognize the first group of international scientists who were linked by their common purpose to promote neuroendocrinology throughout the world. This article is protected by copyright. All rights reserved.
November 19, 2017: Journal of Neuroendocrinology
https://www.readbyqxmd.com/read/29151179/comparison-of-three-analgesic-drug-regimens-with-twelfth-subcostal-nerve-block-for-pain-control-during-extracorporeal-shock-wave-lithotripsy
#2
Miguel Maldonado-Avila, Leopoldo Mateo Garduño-Arteaga, Roberto Alejandro Vela-Mollinedo, Jorge Jaspersen-Gastelum, Francisco Virgen-Gutierrez, Marcos Del Rosario-Santiago, Victor Rios-Davila
INTRODUCTION AND OBJECTIVE: Extracorporeal shock wave lithotripsy (ESWL) is the first-line treatment in the majority of cases of upper urinary tract stones. Since its introduction, attempts have been made to establish the ideal accompanying analgesic method to enable the application of shock waves of adequate duration and intensity for efficacious stone fragmentation. An open, randomized, prospective, longitudinal, comparative, and experimental clinical study was conducted to evaluate the efficacy of subcostal nerve block with lidocaine, comparing it in combination with tramadol or diclofenac for pain control during ESWL...
November 18, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/29150826/rethinking-human-nonhuman-primate-contact-and-pathogenic-disease-spillover
#3
REVIEW
Victor Narat, Lys Alcayna-Stevens, Stephanie Rupp, Tamara Giles-Vernick
Zoonotic transmissions are a major global health risk, and human-animal contact is frequently raised as an important driver of transmission. A literature examining zooanthroponosis largely agrees that more human-animal contact leads to more risk. Yet the basis of this proposition, the term contact, has not been rigorously analyzed. To understand how contact is used to explain cross-species spillovers, we conducted a multi-disciplinary review of studies addressing human-nonhuman primate (NHP) engagements and pathogenic transmissions and employing the term contact...
November 17, 2017: EcoHealth
https://www.readbyqxmd.com/read/29150737/risk-of-active-tuberculosis-in-patients-with-inflammatory-arthritis-receiving-tnf-inhibitors-a-look-beyond-the-baseline-tuberculosis-screening-protocol
#4
Alina Soare, Ana Maria Gheorghiu, Victoria Aramă, Dragoș Bumbăcea, Rucsandra Dobrotă, Raida Oneaţă, Simona Pintilie, Mihaela Milicescu, Ioan Ancuţa, Andrei Martin, Mariana Sasu, Claudia Ciofu, Liviu Macovei, Victor Stoica, Mihai Bojincă, Carina Mihai
Tuberculosis (TB) is a major concern in patients receiving TNF inhibitors (TNFi). This study aimed to assess the incidence of active TB and the efficacy of TB prevention measures used over the years, and to determine risk factors for developing TB, in a single-centre cohort of patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA) and ankylosing spondylitis (AS) receiving TNFi. Data of all patients in whom treatment with TNFi was initiated in our rheumatology clinic until December 1st 2014 have been retrospectively analysed...
November 17, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/29149706/exploring-the-impact-of-route-of-administration-on-medication-acceptance-in-hospitalized-patients-implications-for-venous-thromboembolism-prevention
#5
Victor O Popoola, Farrah Tavakoli, Brandyn D Lau, Matthew Lankiewicz, Patricia Ross, Peggy Kraus, Dauryne Shaffer, Deborah B Hobson, Jonathan K Aboagye, Norma A Farrow, Elliott R Haut, Michael B Streiff
BACKGROUND: Non-administration of venous thromboembolism (VTE) prophylaxis contributes to preventable patient harm. We hypothesized that non-administration would be more common for parenteral VTE prophylaxis than oral infectious disease or cardiac prophylaxis or for treatment medications. The primary study goal was to determine if non-administration of parenteral VTE prophylaxis is more frequent than other prophylactic or treatment medications. METHODS: In this retrospective cohort study of consecutive admissions we used descriptive statistics and risk ratios (RR) to compare the number of non-administered doses of VTE prophylaxis, oral infectious disease and cardiovascular prophylaxis and treatment medications...
October 21, 2017: Thrombosis Research
https://www.readbyqxmd.com/read/29149682/signalling-for-b-cell-survival
#6
REVIEW
Edina Schweighoffer, Victor Lj Tybulewicz
The number of mature B cells is carefully controlled by signalling from receptors that support B cell survival. The best studied of these are the B cell antigen receptor (BCR) and BAFFR. Recent work has shown that signalling from these receptors is closely linked, involves the CD19 co-receptor, and leads to activation of canonical and non-canonical NF-κB pathways, ERK1, ERK2 and ERK5 MAP kinases, and PI-3 kinases. Importantly, studies show that investigation of the importance of signalling molecules in cell survival requires the use of inducible gene deletions within mature B cells...
November 14, 2017: Current Opinion in Cell Biology
https://www.readbyqxmd.com/read/29149669/effective-clinical-classification-of-chronic-epilepsy-into-focal-and-generalized-a-cross-sectional-study
#7
Shambhu Kumar, Mamta Bhushan Singh, Garima Shukla, Sreenivas Vishnubhatla, M V Padma Srivastava, Vinay Goyal, Kameshwar Prasad, Victor Patterson
PURPOSE: Investigations such as EEG and brain imaging are often difficult to obtain in primary care settings of resource-limited regions impacting millions of epilepsy patients. We wanted to test the hypothesis that classification of chronic epilepsy into focal and generalized based on clinical history and examination alone would be comparable to making such a classification with additional inputs from EEG and brain imaging. METHODS: Two investigators independently classified consecutive chronic epilepsy patients into focal, generalized and unclassified epilepsy...
November 9, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/29149141/music-induced-analgesia-in-chronic-pain-conditions-a-systematic-review-and-meta-analysis
#8
Eduardo A Garza-Villarreal, Victor Pando, Peter Vuust, Christine Parsons
BACKGROUND: Music is increasingly used as an adjuvant for the management of chronic pain (CP), as it is non-invasive, inexpensive, and patients usually report positive experiences with it. However, little is known about its clinical efficacy in chronic pain patients. OBJECTIVES: We aimed to determine the effect of music as an adjuvant for chronic pain, as well as to identify characteristics of music interventions associated with positive clinical outcomes. STUDY DESIGN: In this systematic review and meta-analysis, we investigated randomized controlled trials (RCTs) of adult patients that reported any type of music intervention for chronic pain, chosen by the researcher or patient, lasting for any duration...
November 2017: Pain Physician
https://www.readbyqxmd.com/read/29148982/a-dentin-derived-hydrogel-bioink-for-3d-printing-of-cell-laden-scaffolds-for-regenerative-dentistry
#9
Avathamsa Athirasala, Anthony Tahayeri, Greeshma Thrivikraman, Cristiane Miranda Franca, Nelson Monteiro, Victor Tran, Jack Ferracane, Luiz Bertassoni
Recent studies in tissue engineering have adopted extracellular matrix (ECM) derived scaffolds as natural and cytocompatible microenvironments for tissue regeneration. The dentin matrix, specifically, has been shown to be associated with a host of soluble and insoluble signaling molecules that can promote odontogenesis. Here, we have developed a novel bioink, blending printable alginate (3% w/v) hydrogels with the soluble and insoluble fractions of the dentin matrix. We have optimized the printing parameters and the concentrations of the individual components of the bioink for print accuracy, cell viability and odontogenic potential...
November 17, 2017: Biofabrication
https://www.readbyqxmd.com/read/29148920/the-unexpected-impact-of-vaccines-on-secondary-bacterial-infections-following-influenza
#10
Amber M Smith, Victor C Huber
Influenza virus infections remain a significant health burden worldwide, despite available vaccines. Factors that contribute to this include a lack of broad coverage by current vaccines and continual emergence of novel virus strains. Further complicating matters, when influenza viruses infect a host, severe infections can develop when bacterial pathogens invade. Secondary bacterial infections (SBIs) contribute to a significant proportion of influenza-related mortality, with Streptococcus pneumoniae, Staphylococcus aureus, Streptococcus pyogenes, and Haemophilus influenzae as major coinfecting pathogens...
November 17, 2017: Viral Immunology
https://www.readbyqxmd.com/read/29148238/use-of-resin-based-provisional-material-to-create-the-posterior-palatal-seal-in-complete-denture-definitive-impressions
#11
Victor Eduardo de Souza Batista, Aljomar José Vechiato-Filho, Eduardo Piza Pellizzer, Fellippo Ramos Verri
The purpose of this article was to present an alternative procedure using resin-based provisional material to create the posterior palatal seal (PPS). This method offers more practicality in clinical routine and increased control for addition of material to create the PPS when compared to traditional techniques such as the use of impression wax.
November 17, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/29148183/trends-and-predictors-of-appropriate-complementary-feeding-practices-in-nepal-an-analysis-of-national-household-survey-data-collected-between-2001-and-2014
#12
Muzi Na, Victor M Aguayo, Mary Arimond, Pradiumna Dahal, Bikash Lamichhane, Rajkumar Pokharel, Stanley Chitekwe, Christine P Stewart
There is evidence that suboptimal complementary feeding contributes to poor child growth. However, little is known about time trends and determinants of complementary feeding in Nepal, where the prevalence of child undernutrition remains unacceptably high. The objective of the study was to examine the trends and predictors of suboptimal complementary feeding in Nepali children aged 6-23 months using nationally representative data collected from 2001 to 2014. Data from the 2001, 2006, and 2011 Nepal Demographic and Health Surveys and the 2014 Multiple Indicator Cluster Survey were used to estimate the prevalence, trends and predictors of four WHO-UNICEF complementary feeding indicators: timely introduction of complementary foods (INTRO), minimum meal frequency (MMF), minimum dietary diversity (MDD), and minimum acceptable diet (MAD)...
November 17, 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/29148156/long-term-outcomes-for-different-surgical-strategies-to-treat-left-ventricular-outflow-tract-obstruction-in-hypertrophic-cardiomyopathy
#13
Richard Collis, Oliver Watkinson, Constantinos O'Mahony, Oliver P Guttmann, Antonis Pantazis, Maria Tome-Esteban, Victor Tsang, Venkatachalam Chandrasekaran, Christopher G A McGregor, Perry M Elliott
AIMS: Surgical intervention is used to treat dynamic left ventricular outflow tract obstruction (LVOTO) in hypertrophic cardiomyopathy. This study assesses the effect of different surgical strategies on long-term mortality and morbidity. METHODS AND RESULTS: In total, 347 patients underwent surgical intervention for LVOTO (1988-2015). Group A (n = 272) underwent septal myectomy; Group B (n = 33), septal myectomy and mitral valve (MV) repair; Group C (n = 22), myectomy and MV replacement; and Group D (n = 20), MV replacement alone...
November 16, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29147578/modelling-historical-changes-in-the-force-of-infection-of-chagas-disease-to-inform-control-and-elimination-programmes-application-in-colombia
#14
Zulma M Cucunubá, Pierre Nouvellet, Lesong Conteh, Mauricio Javier Vera, Victor Manuel Angulo, Juan Carlos Dib, Gabriel Jaime Parra-Henao, María Gloria Basáñez
Background: WHO's 2020 milestones for Chagas disease include having all endemic Latin American countries certified with no intradomiciliary Trypanosoma cruzi transmission, and infected patients under care. Evaluating the variation in historical exposure to infection is crucial for assessing progress and for understanding the priorities to achieve these milestones. Methods: Focusing on Colombia, all the available age-structured serological surveys (undertaken between 1995 and 2014) were searched and compiled...
2017: BMJ Global Health
https://www.readbyqxmd.com/read/29147547/multi-dimensional-charge-transport-in-supramolecular-helical-foldamer-assemblies
#15
Alejandro Méndez-Ardoy, Nagula Markandeya, Xuesong Li, Yu-Tang Tsai, Gilles Pecastaings, Thierry Buffeteau, Victor Maurizot, Luca Muccioli, Frédéric Castet, Ivan Huc, Dario M Bassani
Aromatic foldamers are bioinspired architectures whose potential use in materials remains largely unexplored. Here we report our investigation of vertical and horizontal charge transport over long distances in helical oligo-quinolinecarboxamide foldamers organized as single monolayers on Au or SiO2. Conductive atomic force microscopy showed that vertical conductivity is efficient and that it displays a low attenuation with foldamer length (0.06 Å(-1)). In contrast, horizontal charge transport is found to be negligible, demonstrating the strong anisotropy of foldamer monolayers...
October 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/29146983/precise-control-of-alloying-sites-of-bimetallic-nanoclusters-via-surface-motif-exchange-reaction
#16
Qiaofeng Yao, Yan Feng, Victor Fung, Yong Yu, De-En Jiang, Jun Yang, Jianping Xie
Precise control of alloying sites has long been a challenging pursuit, yet little has been achieved for the atomic-level manipulation of metallic nanomaterials. Here we describe utilization of a surface motif exchange (SME) reaction to selectively replace the surface motifs of parent [Ag44(SR)30](4-) (SR = thiolate) nanoparticles (NPs), leading to bimetallic NPs with well-defined molecular formula and atomically-controlled alloying sites in protecting shell. A systematic mass (and tandem mass) spectrometry analysis suggests that the SME reaction is an atomically precise displacement of SR-Ag(I)-SR-protecting modules of Ag NPs by the incoming SR-Au(I)-SR modules, giving rise to a core-shell [Ag32@Au12(SR)30](4-)...
November 16, 2017: Nature Communications
https://www.readbyqxmd.com/read/29146860/complete-genome-sequence-of-a-novel-nonnodulating-rhizobium-species-isolated-from-agave-americana-l-rhizosphere
#17
Víctor Manuel Ruíz-Valdiviezo, Marco Antonio Rogel-Hernandez, Gabriela Guerrero, Clara Ivette Rincón-Molina, Luis Galdino García-Perez, Federico Antonio Gutiérrez-Miceli, Juan José Villalobos-Maldonado, Aline López-López, Esperanza Martinez-Romero, Reiner Rincón-Rosales
We report here the complete genome sequence of Rhizobium sp. strain ACO-34A, isolated from Agave americana L. rhizosphere. No common nod genes were found, but there were nif genes for nitrogen fixing. A low average nucleotide identity to reported species supports its designation as a novel Rhizobium species that has a complete ribosomal operon in a plasmid.
November 16, 2017: Genome Announcements
https://www.readbyqxmd.com/read/29146660/changing-physical-activity-behaviour-for-people-with-multiple-sclerosis-protocol-of-a-randomised-controlled-feasibility-trial-istep-ms
#18
Jennifer M Ryan, Jennifer Fortune, Andrea Stennett, Cherry Kilbride, Nana Anokye, Christina Victor, Wendy Hendrie, Mohamed Abdul, Lorraine DeSouza, Grace Lavelle, Debbie Brewin, Lee David, Meriel Norris
INTRODUCTION: Although physical activity may reduce disease burden, fatigue and disability, and improve quality of life among people with multiple sclerosis (MS), many people with MS are physically inactive and spend significant time in sedentary behaviour. Behaviour change interventions may assist people with MS to increase physical activity and reduce sedentary behaviour. However, few studies have investigated their effectiveness using objective measures of physical activity, particularly in the long term...
November 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/29146553/impact-of-marital-status-on-outcomes-following-st-segment-elevation-myocardial-infarction
#19
Moo Hyun Kim, Kwang Min Lee, Soo Jin Kim, So Yeon Kim, Jong Seong Park, Young Rak Cho, Kyungil Park, Tae Ho Park, Young Dae Kim, Victor Serebruany
BACKGROUND: Mood disorders, depression, and loneliness are established risk factors for thrombotic occlusions. Social relationships in general, and marital status in particular may play a role in predicting cardiovascular outcomes and survival after ST-segment elevation myocardial infarction (STEMI), but the evidence is inconclusive especially in Asians. METHODS: The Korean patients presented with STEMI (n=980) constituted married (n=780); or widowed, divorced, or single (WDS, n=200) groups...
July 22, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29146485/in-frame-variants-in-flna-proximal-rod-1-domain-associate-with-a-predominant-cardiac-valvular-phenotype
#20
Luis Fernández, Jair Tenorio, Coral Polo-Vaquero, Elena Vallespín, María Palomares-Bralo, Sixto García-Miñaúr, Fernando Santos-Simarro, Pedro Arias, Hernán Carnicer, Silvina Giannivelli, Juan Medina, Rosa Pérez-Piaya, Jorge Solís, Mónica Rodríguez, Alexandra Villagrá, Laura Rodríguez, Julián Nevado, Víctor Martínez-Glez, Karen E Heath, Pablo Lapunzina
INTRODUCTION AND OBJECTIVES: X-linked cardiac valvular dysplasia is a rare form of male-specific congenital heart defect mainly characterized by myxomatous degeneration of the atrioventricular valves with variable hemodynamic consequences. It is caused by genetic defects in FLNA-encoded filamin A, a widely expressed actin-binding protein that regulates cytoskeleton organization. Filamin A loss of function has also been associated with often concurring neurologic and connective tissue manifestations, with mutations in the first half of the Rod 1 domain apparently expressing the full cardiac phenotype...
November 13, 2017: Revista Española de Cardiología
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