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https://www.readbyqxmd.com/read/28438012/smartphone-based-dual-modality-imaging-system-for-quantitative-detection-of-color-or-fluorescent-lateral-flow-immunochromatographic-strips
#1
Yafei Hou, Kan Wang, Kun Xiao, Weijian Qin, Wenting Lu, Wei Tao, Daxiang Cui
Nowadays, lateral flow immunochromatographic assays are increasingly popular as a diagnostic tool for point-of-care (POC) test based on their simplicity, specificity, and sensitivity. Hence, quantitative detection and pluralistic popular application are urgently needed in medical examination. In this study, a smartphone-based dual-modality imaging system was developed for quantitative detection of color or fluorescent lateral flow test strips, which can be operated anywhere at any time. In this system, the white and ultra-violet (UV) light of optical device was designed, which was tunable with different strips, and the Sobel operator algorithm was used in the software, which could enhance the identification ability to recognize the test area from the background boundary information...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28438009/modulation-format-free-and-automatic-bias-control-for-optical-iq-modulators-based-on-dither-correlation-detection
#2
Xiaolei Li, Lei Deng, Xiaoman Chen, Mengfan Cheng, Songnian Fu, Ming Tang, Deming Liu
A novel automatic bias control (ABC) method for optical in-phase and quadrature (IQ) modulator is proposed and experimentally demonstrated. In the proposed method, two different low frequency sine wave dither signals are generated and added on to the I/Q bias signal respectively. Instead of power monitoring of the harmonics of the dither signal, dither-correlation detection is proposed and used to adjust the bias voltages of the optical IQ modulator. By this way, not only frequency spectral analysis isn't required but also the directional bias adjustment could be realized, resulting in the decrease of algorithm complexity and the growth of convergence rate of ABC algorithm...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437993/integrated-optical-force-sensors-using-focusing-photonic-crystal-arrays
#3
Jingkun Guo, Richard A Norte, S Gröblacher
Mechanical oscillators are at the heart of many sensor applications. Recently several groups have developed oscillators that are probed optically, fabricated from high-stress silicon nitride films. They exhibit outstanding force sensitivities of a few aN/Hz<sup>1/2</sup> and can also be made highly reflective, for efficient detection. The optical read-out usually requires complex experimental setups, including positioning stages and bulky cavities, making them impractical for real applications. In this paper we propose a novel way of building fully integrated all-optical force sensors based on low-loss silicon nitride mechanical resonators with a photonic crystal reflector...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437954/microstructured-fbg-hydrogen-sensor-based-on-pt-loaded-wo-sub-3-sub
#4
Xian Zhou, Yutang Dai, Joseph Muna Karanja, Fufei Liu, Minghong Yang
Hydrogen gas sensing properties of Pt-WO<sub>3</sub> films on spiral microstructured fiber Bragg grating (FBG) has been demonstrated. Pt-WO<sub>3</sub> film was prepared by hydrothermal method. The spiral microsturctured FBG was fabricated using femtosecond laser. Spiral microstructure FBG hydrogen sensor can detect hydrogen concentration from 0.02% H<sub>2</sub> to 4% H<sub>2</sub> at room temperature, and the response time is shortened from a few minutes to 10~30 s...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437948/uv-sensitive-superconducting-nanowire-single-photon-detectors-for-integration-in-an-ion-trap
#5
D H Slichter, V B Verma, D Leibfried, R P Mirin, S W Nam, D J Wineland
We demonstrate superconducting nanowire single photon detectors with 76 ± 4% system detection efficiency at a wavelength of 315 nm and an operating temperature of 3.2 K, with a background count rate below 1 count per second at saturated detection efficiency. We propose integrating these detectors into planar surface electrode radio-frequency Paul traps for use in trapped ion quantum information processing. We operate detectors integrated into test ion trap structures at 3.8 K both with and without typical radio-frequency trapping electric fields...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437935/terahertz-artificial-material-based-on-integrated-metal-rod-array-for-phase-sensitive-fluid-detection
#6
Borwen You, Ching-Yu Chen, Chin-Ping Yu, Tze-An Liu, Toshiaki Hattori, Ja-Yu Lu
A terahertz artificial material composed of metal rod array is experimentally investigated on its transmission spectral property and successfully incorporated into microfluidics as a miniaturized terahertz waveguide with an extended optical-path-length for label-free fluidic sensing. Theoretical and experimental characterizations of terahertz transmission spectra show that the wave guidance along the metal rod array originates from the resonance of transverse-electric-polarized waves within the metal rod slits...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437934/dual-channel-multilayer-coated-surface-plasmon-resonance-sensor-for-dual-refractive-index-range-measurements
#7
Mengdi Lu, Wei Peng, Qiang Liu, Yun Liu, Lixia Li, Yuzhang Liang, Jean-Francois Masson
We present a novel multilayer-coated surface plasmon resonance sensor for dual refractive index range measurements based on a capillary structure. The sensing elements include an internally coated Ag layer and an externally coated bilayer of Au with an overlayer of thin indium tin oxide (ITO). The internal Ag layer was sensitive to higher refractive index (RI) medium while the external Au/ITO layer was sensitive to lower refractive index medium. We evaluated the sensor performance by measuring RI changes in two channels, RI sensitivities were -1951 nm/RIU and 2496 nm/RIU, respectively...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437907/back-focal-plane-displacement-detection-using-side-scattered-light-in-dual-beam-fiber-optic-traps
#8
Wei Xiong, Guangzong Xiao, Xiang Han, Jinhua Zhou, Xinlin Chen, Hui Luo
In optical traps the position of a trapped bead is usually determined by measuring the intensity distribution of the forward-scattered light and the back-scattered light. In this paper we demonstrate that this position can be determined using the side-scattered light. A quadrant photodiode is used to monitor the position of an optically trapped object in a dual-beam fiber-optic trap by measurement of intensity shifts in the back focal plane of the objective that is perpendicular to the propagating beam. An approximated model based on ray optics is presented with numerical results that describe the use of the side-scattered light for position detection...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437896/variability-of-apparent-and-inherent-optical-properties-of-sediment-laden-waters-in-large-river-basins-lessons-from-in-situ-measurements-and-bio-optical-modeling
#9
Sylvain Pinet, Jean-Michel Martinez, Sylvain Ouillon, Bruno Lartiges, Raul Espinoza Villar
We investigated the relationships between inherent and apparent optical properties (IOP and AOP, respectively) and suspended sediment concentrations (SSC) in the main Amazonian river waters. In situ measurements of SSC, remote sensing reflectance (R<sub>rs</sub>), the diffuse light attenuation coefficient (K<sub>d</sub>) and the total and non-algal particle (NAP) absorption coefficients (a<sub>TOT</sub> and a<sub>NAP</sub>, respectively) were conducted during three sampling trips along different streams of the Amazon River catchment (104 stations)...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437741/use-of-nuclear-receptor-luciferase-based-bioassays-to-detect-endocrine-active-chemicals-in-a-biosolids-biochar-amended-soil
#10
Carolyn G Anderson, Geetika Joshi, Daniel A Bair, Charlotte Oriol, Guochun He, Sanjai J Parikh, Michael S Denison, Kate M Scow
Biosolids are a potentially valuable source of carbon and nutrients for agricultural soils; however, potential unintended impacts on human health and the environment must be considered. Virtually all biosolids contain trace amounts endocrine-disrupting chemicals derived from human use of pharmaceuticals and personal care products (PPCPs). One potential way to reduce the bioavailability of PPCPs is to co-apply biosolids with biochar to soil, because biochar's chemical (e.g., aromaticity) and physical properties (e...
April 8, 2017: Chemosphere
https://www.readbyqxmd.com/read/28437719/matrix-assisted-laser-desorption-ionization-mass-spectrometric-imaging-of-olanzapine-in-a-single-hair-using-esculetin-as-a-matrix
#11
Hang Wang, Ying Wang, Ge Wang, Lizhi Hong
Matrix-assisted laser desorption/ionization-mass spectrometric imaging (MALDI-MSI) for the analysis of intact hair is a powerful tool for monitoring changes in drug consumption. The embedding of a low drug concentration in the hydrophobic hair matrix makes it difficult to extract and detect, and requires an improved method to increase detection sensitivity. In this study, an MSI method using MALDI-Fourier transform ion cyclotron resonance was developed for direct identification and imaging of olanzapine in hair samples using the positive ion mode...
April 18, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28437716/development-of-a-derivatization-method-for-the-quantification-of-hydrogen-sulfide-and-its-application-in-vascular-calcification-rats
#12
Xiao-Xin Tan, Kao-Qi Lian, Xiang Li, Nan Li, Wei Wang, Wei-Jun Kang, Hong-Mei Shi
Hydrogen sulfide (H2S) plays major functional and structural roles in diverse physiological functions and the pathogenesis of a variety of disorders in biological matrices. The significance of H2S has prompted the development of sensitive and selective methods to determine its concentration in biological samples. The fluorescent reagent monobromobimane (MBB) has been widely used to measure various thiol-containing species through alkylation. MBB may prevent the oxidation of sulfide and the reaction of sulfide with several different species (such as superoxide radicals, hydrogen peroxide and peroxynitrite)...
April 13, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28437701/a-high-performance-and-highly-controllable-core-shell-imprinted-sensor-based-on-the-surface-enhanced-raman-scattering-for-detection-of-r6g-in-water
#13
Hongji Li, Jiaqi Jiang, Zirun Wang, Xiaonan Wang, Xiqing Liu, Yongsheng Yan, Chunxiang Li
A novel, sensitive sensor material combined the technique of surface enhance Raman scattering (SERS) and molecular imprinting was prepared. It was used the amino-functionalized SiO2 nanospheres as the supporting materials and anchored Ag nanoparticles on the surface by the function of coordination between Ag(+) and NH2(-). Then, it was used that the Rhodamine 6G (R6G) as the template, acrylamide (AM) as functional monomer, ethyleneglycol dimethacrylate (EGDMA) as cross-linker, 2,2'-azobis(2-methylpropionitrile) (AIBN) as initiator to prepare the core-shell molecular imprinted polymers...
April 6, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28437700/nanomolar-electrochemical-detection-of-caffeic-acid-in-fortified-wine-samples-based-on-gold-palladium-nanoparticles-decorated-graphene-flakes
#14
Kokulnathan Thangavelu, Nehru Raja, Shen-Ming Chen, Wei-Cheng Liao
Amalgamation of noble metal nanomaterials on graphene flakes potentially paves one way to improve their physicochemical properties. This paper deals with the simultaneous electrochemical deposition of gold and palladium nanoparticles on graphene flakes (Au/PdNPs-GRF) for the sensitive determination of caffeic acid (CA). The physiochemical properties of the prepared Au/PdNPs-GRF was characterized by using numerous analytical techniques such as scanning electron microscopy, electron dispersive X-ray spectroscopy, Fourier transform infrared spectroscopy, X-ray powder diffraction, Raman spectroscopy and electrochemical impedance spectroscopy...
April 13, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28437689/aie-active-turn-off-fluorescent-probe-for-the-detection-of-cu-2-ions
#15
Mehboobali Pannipara, Abdullah G Al-Sehemi, Abul Kalam, Abdullah M Asiri, Muhammad Nadeem Arshad
A novel AIE active Schiff base compound (receptor 1) has been designed, synthesized and characterized spectroscopically. Receptor 1 show weak emission in solution state but emit strongly in solid state. The investigation on the AIE behavior of receptor 1 using solvent-non-solvent (THF-Water) interaction reveals a maximum PL intensity on reaching the water fraction 90% (fw=90) due to nanoaggregation. Furthermore, demonstration of metal ion sensing application of receptor 1 unravel that it could act as selective and sensitive sensor for Cu(2+) ions in aqueous solution via fluorescence "turn-off" manner...
April 20, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28437685/rapid-label-free-identification-of-klebsiella-pneumoniae-antibiotic-resistant-strains-by-the-drop-coating-deposition-surface-enhanced-raman-scattering-method
#16
Youjin Cheong, Young Jin Kim, Heeyoon Kang, Samjin Choi, Hee Joo Lee
Although many methodologies have been developed to identify unknown bacteria, bacterial identification in clinical microbiology remains a complex and time-consuming procedure. To address this problem, we developed a label-free method for rapidly identifying clinically relevant multilocus sequencing typing-verified quinolone-resistant Klebsiella pneumoniae strains. We also applied the method to identify three strains from colony samples, ATCC70063 (control), ST11 and ST15; these are the prevalent quinolone-resistant K...
April 20, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28437640/the-woven-fiber-organic-electrochemical-transistors-based-on-polypyrrole-nanowires-reduced-graphene-oxide-composites-for-glucose-sensing
#17
Yuedan Wang, Xing Qing, Quan Zhou, Yang Zhang, Qiongzhen Liu, Ke Liu, Wenwen Wang, Mufang Li, Zhentan Lu, Yuanli Chen, Dong Wang
Novel woven fiber organic electrochemical transistors based on polypyrrole (PPy) nanowires and reduced graphene oxide (rGO) have been prepared. SEM revealed that the introduction of rGO nanosheets could induce the growth and increase the amount of PPy nanowires. Moreover, it could enhance the electrical performance of fiber transistors. The hybrid transistors showed high on/off ratio of 10(2), fast switch speed, and long cycling stability. The glucose sensors based on the fiber organic electrochemical transistors have also been investigated, which exhibited outstanding sensitivity, as high as 0...
April 14, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28437639/a-novel-biosensor-based-on-boronic-acid-functionalized-metal-organic-frameworks-for-the-determination-of-hydrogen-peroxide-released-from-living-cells
#18
Hongxia Dai, Wenjuan Lü, Xianwei Zuo, Qian Zhu, Congjie Pan, Xiaoying Niu, Juanjuan Liu, HongLi Chen, Xingguo Chen
In this work, we report a durable and sensitive H2O2 biosensor based on boronic acid functionalized metal-organic frameworks (denoted as MIL-100(Cr)-B) as an efficient immobilization matrix of horseradish peroxidase (HRP). MIL-100(Cr)-B features a hierarchical porous structure, extremely high surface area, and sufficient recognition sites, which can significantly increase HRP loading and prevent them from leakage and deactivation. The H2O2 biosensor can be easily achieved without any complex processing. Meanwhile, the immobilized HRP exhibited enhanced stability and remarkable catalytic activity towards H2O2 reduction...
April 18, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28437507/effects-of-experimental-pain-and-lidocaine-on-mechanical-somatosensory-profile-and-face-perception
#19
Yuri Martins Costa, Eduardo E Castrillon, Leonardo Rigoldi Bonjardim, Paulo César Rodrigues Conti, Lene Baad-Hansen, Peter Svensson
AIMS: To assess the effects of experimental muscle pain and topical lidocaine applied to the skin overlying the masseter muscle on the mechanical somatosensory profile and face perception of the masseter muscle in healthy participants. METHODS: A total of 28 healthy participants received a 45-minute application of a lidocaine or placebo patch to the skin overlying the masseter muscle followed by one injection of 0.2 mL sterile solution of monosodium glutamate. Measurements were taken four times during each session of quantitative sensory testing (QST) (T0 = baseline, T1 = 45 minutes after patch application, T2 = immediately after glutamate injection, and T3 = 25 minutes after the glutamate injection), and the following variables were measured: mechanical detection threshold (MDT), mechanical pain threshold (MPT), pressure pain threshold (PPT), pain report (pain on palpation, pain spreading on palpation, and pain intensity), pain drawing, and perceptual distortion...
April 2017: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/28437466/stage-call-cardiovascular-reactivity-to-audition-stress-in-musicians
#20
Theerasak Chanwimalueang, Lisa Aufegger, Tricia Adjei, David Wasley, Cinzia Cruder, Danilo P Mandic, Aaron Williamon
Auditioning is at the very center of educational and professional life in music and is associated with significant psychophysical demands. Knowledge of how these demands affect cardiovascular responses to psychosocial pressure is essential for developing strategies to both manage stress and understand optimal performance states. To this end, we recorded the electrocardiograms (ECGs) of 16 musicians (11 violinists and 5 flutists) before and during performances in both low- and high-stress conditions: with no audience and in front of an audition panel, respectively...
2017: PloS One
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