keyword
MENU ▼
Read by QxMD icon Read
search

Behavioural insights

keyword
https://www.readbyqxmd.com/read/28534911/cellular-orientation-is-guided-by-strain-gradients
#1
Sophie Chagnon-Lessard, Hubert Jean-Ruel, Michel Godin, Andrew E Pelling
The strain-induced reorientation response of cyclically stretched cells has been well characterized in uniform strain fields. In the present study, we comprehensively analyse the behaviour of human fibroblasts subjected to a highly non-uniform strain field within a polymethylsiloxane microdevice. Our results indicate that the strain gradient amplitude and direction regulate cell reorientation through a coordinated gradient avoidance response. We provide critical evidence that strain gradient is a key physical cue that can guide cell organization...
May 23, 2017: Integrative Biology: Quantitative Biosciences From Nano to Macro
https://www.readbyqxmd.com/read/28532070/ribose-mediated-crosslinking-of-collagen-hydroxyapatite-hybrid-scaffolds-for-bone-tissue-regeneration-using-biomimetic-strategies
#2
Gopal Shankar Krishnakumar, Natalia Gostynska, Elisabetta Campodoni, Massimiliano Dapporto, Monica Montesi, Silvia Panseri, Anna Tampieri, Elizaveta Kon, Maurilio Marcacci, Simone Sprio, Monica Sandri
This study explores for the first time the application of ribose as a highly biocompatible agent for the crosslinking of hybrid mineralized constructs, obtained by bio-inspired mineralization of self-assembling Type I collagen matrix with magnesium-doped-hydroxyapatite nanophase, towards a biomimetic mineralized 3D scaffolds (MgHA/Coll) with excellent compositional and structural mimicry of bone tissue. To this aim, two different crosslinking mechanisms in terms of pre-ribose glycation (before freeze drying) and post-ribose glycation (after freeze drying) were investigated...
August 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28530460/unravelling-motor-learning-processes-in-theatre-performers
#3
Emmanuel Jacobs, Ann Hallemans, Jan Gielen, Luc Van den Dries, Annouk Van Moorsel, Jonas Rutgeerts, Nathalie Roussel
Theatre performers, more than common actors, experience high physical loadings. This study aimed at analysing the motor behaviour ofnovice performers (dancers/actors who were introduced to the acting method of Jan Fabre), by investigating the kinematics of a physical acting exercises in a prospective study. Two measurement sessions were organised, before and after the novice performers (n = 13) took part in seven workshops. Total body kinematics were registered using a 3D motion capture system. By using a Principal Component Analysis (PCA), six factors were disseminated out of 30 kinematic parameters: Pelvic Motion, Speed of Progression, Lower Limb Position, Foot Motion, Lower Limb Motion and Trunk Position...
May 22, 2017: Motor Control
https://www.readbyqxmd.com/read/28530040/adolescents-with-hiv-and-transition-to-adult-care-in-the-caribbean-central-america-and-south-america-eastern-europe-and-asia-and-pacific-regions
#4
Heather Bailey, Maria Letícia Santos Cruz, Wipaporn Natalie Songtaweesin, Thanyawee Puthanakit
INTRODUCTION: The HIV epidemics in the Caribbean, Central America and South America (CCASA), Eastern Europe (EE) and Asia and Pacific (AP) regions are diverse epidemics affecting different key populations in predominantly middle-income countries. This narrative review describes the populations of HIV-positive youth approaching adolescence and adulthood in CCASA, EE and AP, what is known of their outcomes in paediatric and adult care to date, ongoing research efforts and future research priorities...
May 16, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28528851/microstructure-evaluation-of-dermally-applicable-liquid-crystals-as-a-function-of-water-content-and-temperature-can-electron-paramagnetic-resonance-provide-complementary-data
#5
Mirjam Gosenca Matjaž, Janez Mravljak, Marija Bešter Rogač, Marjeta Šentjurc, Mirjana Gašperlin, Alenka Zvonar Pobirk
Insight into the microstructure of lyotropic liquid crystals (LCs) is of crucial importance for development of novel dermal delivery systems. Our aim was to evaluate the phase behaviour of dermally applicable LCs composed of isopropyl myristate/Tween 80/lecithin/water, along the dilution line, where phase transitions are predominantly driven by increased water content. Additionally, identification of LC temperature dependence is of great importance for skin application. Selected LCs were evaluated using electron paramagnetic resonance (EPR) plus conventionally used methods of polarization microscopy, small-angle X-ray scattering, differential scanning calorimetry, and rheological measurements...
May 18, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28528246/the-canadian-hypoglycemia-assessment-tool-program-insights-into-rates-and-implications-of-hypoglycemia-from-an-observational-study
#6
Ronnie Aronson, Ronald Goldenberg, Damir Boras, Rasmus Skovgaard, Harpreet Bajaj
OBJECTIVE: The true prevalence of hypoglycemia in insulin-treated patients with diabetes and its impact on patients, employers and healthcare providers is poorly appreciated owing to a paucity of real-world data. The global Hypoglycemia Assessment Tool (HAT) study addressed this issue, and here we report data from the Canadian cohort of patients. METHODS: This noninterventional, 6-month retrospective and 4-week prospective study enrolled patients aged ≥18 years receiving insulin treatment for >12 months from community endocrinology practices...
May 17, 2017: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/28526617/cyclin-dependent-kinase-5-a-novel-avenue-for-alzheimer-s-disease
#7
REVIEW
Anisha S Bhounsule, Lokesh Kumar Bhatt, Kedar S Prabhavalkar, Manisha Oza
Alzheimer's disease (AD) is one of the most frequently encountered diseases in adults with progressive loss of memory and behavioral changes. Inspite of there being an intense research in the field of AD, only a few chemical entities exhibiting anti-AD activity make it through the clinical trials and it is thus need of an hour to develop new drugs or repurpose the existing ones for better management of Alzheimer's disease. Novel therapeutic targets can influence drug discovery in the field of AD. Cyclin Dependent Kinase 5 (Cdk5) which is a serine/threonine kinase can prove to be an upcoming beneficial target to be studied for treating AD...
May 17, 2017: Brain Research Bulletin
https://www.readbyqxmd.com/read/28520432/insights-into-glycol-ethers-alkanol-mixtures-from-a-combined-experimental-and-theoretical-approach
#8
Rafael Alcalde, Alberto Gutiérrez, Mert Atilhan, Jose Luis Trenzado, Santiago Aparicio
The glycol ethers (glymes) + 1-alkanol binary liquid mixtures were characterized from the microscopic and macroscopic viewpoints through a combined experimental and theoretical study. Structuring, dynamics and intermolecular forces were determined using Density Functional Theory and classical molecular dynamics methods. The macroscopic behaviour was studied though the measurement of relevant physicochemical properties and Raman IR studies. The changes in intermolecular forces with mixtures composition, temperature and the effects from the types of glymes as well as 1-alkanols were considered...
May 18, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28517991/self-knowledge-and-risk-in-stratified-medicine
#9
Joshua Hordern
This article considers why and how self-knowledge is important to communication about risk and behaviour change by arguing for four claims. First, it is doubtful that genetic knowledge should properly be called 'self-knowledge' when its ordinary effects on self-motivation and behaviour change seem so slight. Second, temptations towards a reductionist, fatalist, construal of persons' futures through a 'molecular optic' should be resisted. Third, any plausible effort to change people's behaviour must engage with cultural self-knowledge, values and beliefs, catalysed by the communication of genetic risk...
April 2017: New Bioethics: a Multidisciplinary Journal of Biotechnology and the Body
https://www.readbyqxmd.com/read/28514992/sexual-difficulties-faced-by-men-in-the-solomon-islands-a-mixed-methods-study
#10
Paraniala Silas C Lui, Michael P Dunne, Philip Baker, Verzilyn Isom
Background: To date there has been little research into men's sexual and reproductive health in Pacific Island countries. The aim of this study was to describe men's sexual difficulties and barriers to their seeking reproductive health care in the Solomon Islands. Methods: The study included qualitative inquiry (17 individual interviews and three focus group discussions with a total of 21 men) and a quantitative quasi-randomised quota sample household survey (n=400). The prevalence of sexual difficulties and potential risk factors, such as chronic diseases, health risk behaviours, depression and psychological distress were measured using standardised questions translated into pidgin...
May 18, 2017: Sexual Health
https://www.readbyqxmd.com/read/28514523/the-views-of-older-people-and-health-professionals-about-dignity-in-acute-hospital-care
#11
Marcelle Tauber-Gilmore, Gulen Addis, Zainab Zahran, Sally Black, Lesley Baillie, Sue Procter, Christine Norton
AIMS AND OBJECTIVES: This paper reports the findings from interviews conducted as part of a wider study on interventions to support dignified care in older people in acute hospital care. The data in this paper present the interview data. BACKGROUND: Dignity is a complex concept. Despite a plethora of recommendations on how to achieve dignified care it remains unclear how to attain this in practice and what the priorities of patients and staff are in relation to dignity...
May 17, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28514142/non-monotonic-self-deformation-of-cell-nuclei-on-topological-surfaces-with-micropillar-array
#12
Xiangnan Liu, Ruili Liu, Yexin Gu, Jiandong Ding
Cells respond to the mechanical signals from their surroundings and integrate physiochemical signals to initiate intricate mechanochemical processes. While many studies indicate that topological features of biomaterials impact cellular behaviours profoundly, little research has focused on the nuclear response to a mechanical force generated by a topological surface. Here, we fabricated a polymeric micropillar array with an appropriate dimension to induce a severe self-deformation of cell nuclei and investigated how the nuclear shape changed over time...
May 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28513850/small-prey-species-behaviour-and-welfare-implications-for-veterinary-professionals
#13
REVIEW
E Anne McBride
People have obligations to ensure the welfare of animals under their care. Offences under the UK Animal Welfare Act are acts, or failures of action, causing unnecessary suffering. Veterinary professionals need to be able to provide current, scientifically based prophylactic advice, and respect the limits of their expertise. The ethical concept of a life worth living and the Five Freedoms are core to welfare. Behaviour is a central component, both influencing and influenced by physical health. Owners frequently misunderstand the behaviour of small prey mammals and how to meet their needs...
May 17, 2017: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/28511698/using-a-mobile-health-application-to-reduce-alcohol-consumption-a-mixed-methods-evaluation-of-the-drinkaware-track-calculate-units-application
#14
Sophie Attwood, Hannah Parke, John Larsen, Katie L Morton
BACKGROUND: Smartphone applications ("apps") offer promise as tools to help people monitor and reduce their alcohol consumption. To date, few evaluations of alcohol reduction apps exist, with even fewer considering apps already available to the public. The aim of this study was to evaluate an existing publically available app, designed by Drinkaware, a UK-based alcohol awareness charity. METHODS: We adopted a mixed-methods design, analysing routinely collected app usage data to explore user characteristics and patterns of usage...
May 17, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28511647/low-smoke-chulha-in-indian-slums-study-protocol-for-a-randomised-controlled-trial
#15
Megha Thakur, Esther A Boudewijns, Giridhara R Babu, Bjorn Winkens, Luc P de Witte, Jeroen Gruiskens, Preeti Sushama, Cristian T Ghergu, Onno C P van Schayck
BACKGROUND: Biomass fuel is used as a primary cooking source by more than half of the world's population, contributing to a high burden of disease. Although cleaner fuels are available, some households continue using solid fuels because of financial constraints and absence of infrastructure, especially in non-notified slums. The present study documents a randomised controlled study investigating the efficacy of improved cookstove on the personal exposure to air pollution and the respiratory health of women and children in an Indian slum...
May 16, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28511559/migrating-microbes-what-pathogens-can-tell-us-about-population-movements-and-human-evolution
#16
Charlotte J Houldcroft, Jean-Baptiste Ramond, Riaan F Rifkin, Simon J Underdown
BACKGROUND: The biology of human migration can be observed from the co-evolutionary relationship with infectious diseases. While many pathogens are brief, unpleasant visitors to human bodies, others have the ability to become life-long human passengers. The story of a pathogen's genetic code may, therefore, provide insight into the history of its human host. The evolution and distribution of disease in Africa is of particular interest, because of the deep history of human evolution in Africa, the presence of a variety of non-human primates, and tropical reservoirs of emerging infectious diseases...
May 16, 2017: Annals of Human Biology
https://www.readbyqxmd.com/read/28510575/electro-mechanical-dynamics-of-spiral-waves-in-a-discrete-2d-model-of-human-atrial-tissue
#17
Paul Brocklehurst, Haibo Ni, Henggui Zhang, Jianqiao Ye
We investigate the effect of mechano-electrical feedback and atrial fibrillation induced electrical remodelling (AFER) of cellular ion channel properties on the dynamics of spiral waves in a discrete 2D model of human atrial tissue. The tissue electro-mechanics are modelled using the discrete element method (DEM). Millions of bonded DEM particles form a network of coupled atrial cells representing 2D cardiac tissue, allowing simulations of the dynamic behaviour of electrical excitation waves and mechanical contraction in the tissue...
2017: PloS One
https://www.readbyqxmd.com/read/28508130/atmospheric-conditions-create-freeways-detours-and-tailbacks-for-migrating-birds
#18
Judy Shamoun-Baranes, Felix Liechti, Wouter M G Vansteelant
The extraordinary adaptations of birds to contend with atmospheric conditions during their migratory flights have captivated ecologists for decades. During the 21st century technological advances have sparked a revival of research into the influence of weather on migrating birds. Using biologging technology, flight behaviour is measured across entire flyways, weather radar networks quantify large-scale migratory fluxes, citizen scientists gather observations of migrant birds and mechanistic models are used to simulate migration in dynamic aerial environments...
May 15, 2017: Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology
https://www.readbyqxmd.com/read/28507771/association-between-suicidal-symptoms-and-repeat-suicidal-behaviour-within-a-sample-of-hospital-treated-suicide-attempters
#19
Derek P de Beurs, Claudia D van Borkulo, Rory C O'Connor
BACKGROUND: Suicidal behaviour is the end result of the complex relation between many factors which are biological, psychological and environmental in nature. Network analysis is a novel method that may help us better understand the complex association between different factors. AIMS: To examine the relationship between suicidal symptoms as assessed by the Beck Scale for Suicide Ideation and future suicidal behaviour in patients admitted to hospital following a suicide attempt, using network analysis...
May 2017: BJPsych Open
https://www.readbyqxmd.com/read/28493904/factors-associated-with-help-seeking-behaviour-among-individuals-with-major-depression-a-systematic-review
#20
Julia Luise Magaard, Tharanya Seeralan, Holger Schulz, Anna Levke Brütt
Psychological models can help to understand why many people suffering from major depression do not seek help. Using the 'Behavioral Model of Health Services Use', this study systematically reviewed the literature on the characteristics associated with help-seeking behaviour in adults with major depression. Articles were identified by systematically searching the MEDLINE, EMBASE and PsycInfo databases and relevant reference lists. Observational studies investigating the associations between individual or contextual characteristics and professional help-seeking behaviour for emotional problems in adults formally diagnosed with major depression were included...
2017: PloS One
keyword
keyword
77178
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"