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Behavioural insights

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https://www.readbyqxmd.com/read/28211179/what-do-patients-think-about-the-role-of-optometrists-in-providing-advice-about-smoking-and-nutrition
#1
Laura E Downie, Amanda Douglass, Daryl Guest, Peter R Keller
PURPOSE: Tobacco smoking and nutrition are key lifestyle factors with long-term effects on eye health. However, little is known about patients' perceptions and experiences in these areas in relation to the care received from optometrists. The main aim was to survey patients' perceptions and prior experience regarding the role of optometrists in enquiring and providing advice about tobacco smoking and nutrition. METHODS: An anonymous, paper-based survey was distributed to a convenience sample of 225 adults attending the University of Melbourne eye care clinic...
March 2017: Ophthalmic & Physiological Optics: the Journal of the British College of Ophthalmic Opticians (Optometrists)
https://www.readbyqxmd.com/read/28208883/fostering-educational-research-among-medical-teachers-evaluation-of-a-faculty-development-program-in-india
#2
Tripti K Srivastava, Lalitbhushan S Waghmare, Alka Rawekar, Ved Prakash Mishra
INTRODUCTION: Medical education can be enormously benefitted from research. Since clinicians/medical teachers are directly involved in teaching learning processes, they should participate in Educational Research (ER) practices to generate evidence and insights about teaching learning. Faculty Development Program (FDP) has a positive influence amongst health professionals and therefore can prove to be of consequence in instilling a strong educational research culture. AIM: Present study was undertaken to evaluate the efficacy of a Faculty Development Fellowship Program in Medical Education to foster educational research culture amongst medical teachers...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28205226/an-investigation-into-the-effects-of-real-vs-stimulated-cases-and-level-of-experience-on-the-distribution-of-visual-attention-during-induction-of-general-anaesthesia
#3
T Grundgeiger, C Klöffel, S Mohme, T Wurmb, O Happel
In anaesthesia, patient simulators have been used for training and research. However, insights from simulator-based research may only translate to real settings if the simulation elicits the same behaviour as the real setting. To this end, we investigated the effects of the case (simulated case vs. real case) and experience level (junior vs. senior) on the distribution of visual attention during the induction of general anaesthesia. We recorded eye-tracking data from 12 junior and 12 senior anaesthetists inducing general anaesthesia in a simulation room and in an actual operating room (48 recordings)...
February 16, 2017: Anaesthesia
https://www.readbyqxmd.com/read/28202961/early-brain-development-in-infants-at-high-risk-for-autism-spectrum-disorder
#4
Heather Cody Hazlett, Hongbin Gu, Brent C Munsell, Sun Hyung Kim, Martin Styner, Jason J Wolff, Jed T Elison, Meghan R Swanson, Hongtu Zhu, Kelly N Botteron, D Louis Collins, John N Constantino, Stephen R Dager, Annette M Estes, Alan C Evans, Vladimir S Fonov, Guido Gerig, Penelope Kostopoulos, Robert C McKinstry, Juhi Pandey, Sarah Paterson, John R Pruett, Robert T Schultz, Dennis W Shaw, Lonnie Zwaigenbaum, Joseph Piven
Brain enlargement has been observed in children with autism spectrum disorder (ASD), but the timing of this phenomenon, and the relationship between ASD and the appearance of behavioural symptoms, are unknown. Retrospective head circumference and longitudinal brain volume studies of two-year olds followed up at four years of age have provided evidence that increased brain volume may emerge early in development. Studies of infants at high familial risk of autism can provide insight into the early development of autism and have shown that characteristic social deficits in ASD emerge during the latter part of the first and in the second year of life...
February 15, 2017: Nature
https://www.readbyqxmd.com/read/28195685/stigmatization-among-people-living-with-hiv-in-hong-kong-a%C3%A2-qualitative-study
#5
Phoenix K H Mo, Charlson T Y Ng
BACKGROUND: HIV/AIDS is one of the most stigmatized medical conditions across the world. Self-stigma is prevalent among people living with HIV (PLHIV) and a major obstacle to HIV prevention and care. OBJECTIVE: This study aimed to describe the experiences of stigmatization and explore the possible factors that might be associated with stigmatization among PLHIV in Hong Kong. DESIGN: Qualitative in-depth interviews were conducted. SETTING AND PARTICIPANTS: 15 PLHIV were recruited from two local non-governmental organizations on HIV prevention...
February 14, 2017: Health Expectations: An International Journal of Public Participation in Health Care and Health Policy
https://www.readbyqxmd.com/read/28193748/medical-students-unique-experience-of-army-leadership-training-a-qualitative-study
#6
John Earis, J Garner, D Haddock, J Jenkins, V Jha
OBJECTIVES: To assess the interactive experience of first year medical students attending the leadership and management course hosted by a British Army Reserve Field Hospital developed in partnership with Liverpool University. METHODS: 244 students submitted a 1000-word structured reflective learning assignment about their reaction to, learning from and any behaviour and attitude changes as a result of, the training. The assignments were thematically analysed to identify how aspects of the training had impacted upon the students' understanding of leadership and teamwork...
February 13, 2017: Journal of the Royal Army Medical Corps
https://www.readbyqxmd.com/read/28193176/telemonitoring-and-or-self-monitoring-of-blood-pressure-in-hypertension-tasminh4-protocol-for-a-randomised-controlled-trial
#7
Marloes Franssen, Andrew Farmer, Sabrina Grant, Sheila Greenfield, Carl Heneghan, Richard Hobbs, James Hodgkinson, Susan Jowett, Jonathan Mant, Una Martin, Siobhan Milner, Mark Monahan, Emma Ogburn, Rafael Perera-Salazar, Claire Schwartz, Ly-Mee Yu, Richard J McManus
BACKGROUND: Self-monitoring of hypertension is associated with lower systolic blood pressure (SBP). However, evidence for the use of self-monitoring to titrate antihypertensive medication by physicians is equivocal. Furthermore, there is some evidence for the efficacy of telemonitoring in the management of hypertension but it is not clear what this adds over and above self-monitoring. This trial aims to evaluate whether GP led antihypertensive titration using self-monitoring results in lower SBP compared to usual care and whether telemonitoring adds anything to self-monitoring alone...
February 13, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28192650/facile-adhesion-tuning-of-superhydrophobic-surfaces-between-lotus-and-petal-effect-and-their-influence-on-icing-and-de-icing-properties
#8
Md Julker Nine, Tran Thanh Tung, Faisal Khalid Alotaibi, Diana N H Tran, Dusan Losic
Adhesion behaviour of superhydrophobic (SH) surfaces is an active research field related to various engineering applications in controlled microdroplet transportation, self-cleaning, de-icing, biochemical separation, tissue engineering, and water harvesting. Herein, we report a facile approach to control droplet adhesion, bouncing and rolling on properties of SH surfaces by tuning their air-gap and roughness-height by altering the concentrations of poly-dimethyl-siloxane (PDMS). The optimal use of PDMS (4 wt% to 16 wt%) in a dual-scale (nano and micro-particles) composite enables to control specific surface area (SSA), pore-volume, and roughness of matrices that results in a well-controlled adhesion between water droplets and SH surfaces...
February 13, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28187917/oxygen-and-placental-development-parallels-and-differences-with-tumour-biology
#9
Graham J Burton, Eric Jauniaux, Andrew J Murray
Human placentation involves the invasion of the conceptus into the wall of the uterus, and establishment of a blood supply from the maternal spiral arteries. The placenta has therefore been likened to a malignant tumour, albeit a highly regulated one. Oxygen plays an important role in controlling both placental development and tumour behaviour. In the placenta, early development takes place in a physiological low oxygen environment, which undergoes a transition with onset of the full maternal arterial circulation towards the end of the first trimester...
February 1, 2017: Placenta
https://www.readbyqxmd.com/read/28185025/constipation-pathophysiology-and-current-therapeutic-approaches
#10
Amol Sharma, Satish Rao
Chronic constipation is a common, persistent condition affecting many patients worldwide, presenting significant economic burden and resulting in substantial healthcare utilization. In addition to infrequent bowel movements, the definition of constipation includes excessive straining, a sense of incomplete evacuation, failed or lengthy attempts to defecate, use of digital manoeuvres for evacuation of stool, abdominal bloating, and hard consistency of stools. After excluding secondary causes of constipation, chronic idiopathic or primary constipation can be classified as functional defecation disorder, slow-transit constipation (STC), and constipation-predominant irritable bowel syndrome (IBS-C)...
February 10, 2017: Handbook of Experimental Pharmacology
https://www.readbyqxmd.com/read/28183308/reasons-for-unmet-need-for-family-planning-with-attention-to-the-measurement-of-fertility-preferences-protocol-for-a-multi-site-cohort-study
#11
Kazuyo Machiyama, John B Casterline, Joyce N Mumah, Fauzia Akhter Huda, Francis Obare, George Odwe, Caroline W Kabiru, Sharifa Yeasmin, John Cleland
BACKGROUND: Unmet need for family planning points to the gap between women's reproductive desire to avoid pregnancy and contraceptive behaviour. An estimated 222 million women in low- and middle-income countries have unmet need for modern contraception. Despite its prevalence, there has been little rigorous research during the past fifteen years on reasons for this widespread failure to implement childbearing desires in contraceptive practice. There is demographic survey data on women's self-reported reasons for non-use, but these data provide limited insight on the full set of possible obstacles to use, and one may doubt the meaningfulness of explanations provided by non-users alone...
February 9, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28181624/in-situ-tem-observation-of-the-boudouard-reaction-multi-layered-graphene-formation-from-co-on-cobalt-nanoparticles-at-atmospheric-pressure
#12
G Marien Bremmer, Eirini Zacharaki, Anja O Sjåstad, Violeta Navarro, Joost W M Frenken, Patricia J Kooyman
Using a MEMS nanoreactor in combination with a specially designed in situ Transmission Electron Microscope (TEM) holder and gas supply system, we imaged the formation of multiple layers of graphene encapsulating a cobalt nanoparticle, at 1 bar CO : N2 (1 : 1) and 500 °C. The cobalt nanoparticle was imaged live in a TEM during the Boudouard reaction. The in situ/operando TEM studies give insight into the behaviour of the catalyst at the nanometer-scale, under industrially relevant conditions. When switching from Fischer-Tropsch syngas conditions (CO : H2 : N2 1 : 2 : 3 at 1 bar) to CO-rich conditions (CO : N2 1 : 1 at 1 bar), we observed the formation of multi-layered graphene on Co nanoparticles at 500 °C...
February 9, 2017: Faraday Discussions
https://www.readbyqxmd.com/read/28181616/na-k-atpase-as-a-target-for-anticancer-metal-based-drugs-insights-into-molecular-interactions-with-selected-gold-iii-complexes
#13
Aleksandra M Bondžić, Goran V Janjić, Miroslav D Dramićanin, Luigi Messori, Lara Massai, Tatjana N Parac Vogt, Vesna M Vasić
Na/K-ATPase is emerging as an important target for a variety of anticancer metal-based drugs. The interactions of Na/K-ATPase (in its E1 state) with three representative and structurally related cytotoxic gold(iii) complexes, i.e. [Au(bipy)(OH)2][PF6], bipy = 2,2'-bipyridine; [Au(py(dmb)-H)(CH3COO)2], py(dmb)-H = deprotonated 6-(1,1-dimethylbenzyl)-pyridine and [Au(bipy(dmb)-H)(OH)][PF6], bipy(c)-H = deprotonated 6-(1,1-dimethylbenzyl)-2,2'-bipyridine, are investigated here in depth using a variety of spectroscopic methods, in combination with docking studies...
February 9, 2017: Metallomics: Integrated Biometal Science
https://www.readbyqxmd.com/read/28181208/individual-environment-interactions-in-swimming-the-smallest-unit-for-analysing-the-emergence-of-coordination-dynamics-in-performance
#14
Brice Guignard, Annie Rouard, Didier Chollet, John Hart, Keith Davids, Ludovic Seifert
Displacement in competitive swimming is highly dependent on fluid characteristics, since athletes use these properties to propel themselves. It is essential for sport scientists and practitioners to clearly identify the interactions that emerge between each individual swimmer and properties of an aquatic environment. Traditionally, the two protagonists in these interactions have been studied separately. Determining the impact of each swimmer's movements on fluid flow, and vice versa, is a major challenge. Classic biomechanical research approaches have focused on swimmers' actions, decomposing stroke characteristics for analysis, without exploring perturbations to fluid flows...
February 8, 2017: Sports Medicine
https://www.readbyqxmd.com/read/28179164/metacognitive-ability-correlates-with-hippocampal-and-prefrontal-microstructure
#15
Micah Allen, James C Glen, Daniel Müllensiefen, Dietrich Samuel Schwarzkopf, Francesca Fardo, Darya Frank, Martina F Callaghan, Geraint Rees
The ability to introspectively evaluate our experiences to form accurate metacognitive beliefs, or insight, is an essential component of decision-making. Previous research suggests individuals vary substantially in their level of insight, and that this variation is related to brain volume and function, particularly in the anterior prefrontal cortex (aPFC). However, the neurobiological mechanisms underlying these effects are unclear, as qualitative, macroscopic measures such as brain volume can be related to a variety of microstructural features...
February 4, 2017: NeuroImage
https://www.readbyqxmd.com/read/28178232/synthetic-vulnerabilities-of-mesenchymal-subpopulations-in-pancreatic-cancer
#16
Giannicola Genovese, Alessandro Carugo, James Tepper, Frederick Scott Robinson, Liren Li, Maria Svelto, Luigi Nezi, Denise Corti, Rosalba Minelli, Piergiorgio Pettazzoni, Tony Gutschner, Chia-Chin Wu, Sahil Seth, Kadir Caner Akdemir, Elisabetta Leo, Samirkumar Amin, Marco Dal Molin, Haoqiang Ying, Lawrence N Kwong, Simona Colla, Koichi Takahashi, Papia Ghosh, Virginia Giuliani, Florian Muller, Prasenjit Dey, Shan Jiang, Jill Garvey, Chang-Gong Liu, Jianhua Zhang, Timothy P Heffernan, Carlo Toniatti, Jason B Fleming, Michael G Goggins, Laura D Wood, Alessandro Sgambato, Abbas Agaimy, Anirban Maitra, Charles W M Roberts, Huamin Wang, Andrea Viale, Ronald A DePinho, Giulio F Draetta, Lynda Chin
Malignant neoplasms evolve in response to changes in oncogenic signalling. Cancer cell plasticity in response to evolutionary pressures is fundamental to tumour progression and the development of therapeutic resistance. Here we determine the molecular and cellular mechanisms of cancer cell plasticity in a conditional oncogenic Kras mouse model of pancreatic ductal adenocarcinoma (PDAC), a malignancy that displays considerable phenotypic diversity and morphological heterogeneity. In this model, stochastic extinction of oncogenic Kras signalling and emergence of Kras-independent escaper populations (cells that acquire oncogenic properties) are associated with de-differentiation and aggressive biological behaviour...
February 16, 2017: Nature
https://www.readbyqxmd.com/read/28173813/can-we-halt-health-workforce-deterioration-in-failed-states-insights-from-guinea-bissau-on-the-nature-persistence-and-evolution-of-its-hrh-crisis
#17
Giuliano Russo, Enrico Pavignani, Catia Sá Guerreiro, Clotilde Neves
BACKGROUND: Guinea-Bissau is one of the world's poorest and least developed countries. Amid poverty, political turmoil and state withdrawal, its health workforce (HW) has been swamped for the last four decades in a deepening crisis of under-resourcing, poor performance and laissez-faire. METHODS: The present study aimed at analysing the human resources for health (HRH) situation in Guinea-Bissau in light of the recent literature on distressed health systems, with the objective of contributing to understanding the ways health workers react to protracted turmoil, the resulting distortions and the counter-measures that might be considered...
February 7, 2017: Human Resources for Health
https://www.readbyqxmd.com/read/28167396/musical-friends-and-foes-the-social-cognition-of-affiliation-and-control-in-improvised-interactions
#18
Jean-Julien Aucouturier, Clément Canonne
A recently emerging view in music cognition holds that music is not only social and participatory in its production, but also in its perception, i.e. that music is in fact perceived as the sonic trace of social relations between a group of real or virtual agents. While this view appears compatible with a number of intriguing music cognitive phenomena, such as the links between beat entrainment and prosocial behaviour or between strong musical emotions and empathy, direct evidence is lacking that listeners are at all able to use the acoustic features of a musical interaction to infer the affiliatory or controlling nature of an underlying social intention...
February 2, 2017: Cognition
https://www.readbyqxmd.com/read/28164277/event-related-potential-measures-of-executive-functioning-from-preschool-to-adolescence
#19
REVIEW
Michelle Downes, Joe Bathelt, Michelle De Haan
Executive functions are a collection of cognitive abilities necessary for behavioural control and regulation, and are important for school success. Executive deficits are common across acquired and developmental disorders in childhood and beyond. This review aims to summarize how studies using event-related potential (ERP) can provide insight into mechanisms underpinning how executive functions develop in children from preschool to adolescence. We specifically focus on ERP components that are considered to be well-established markers of executive functioning, including the ability to resist distraction (inhibition, N200), hold scenes in mind (visuospatial working memory, contralateral delay activity), attend to specific stimuli (information processing, P300), follow rules (response monitoring, error-related negativity [ERN], and error-related positivity [Pe]), and adjust to feedback (outcome monitoring, feedback-related negativity)...
February 6, 2017: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/28163311/cyclic-di-gmp-second-messenger-extraordinaire
#20
REVIEW
Urs Jenal, Alberto Reinders, Christian Lori
Cyclic dinucleotides (CDNs) are highly versatile signalling molecules that control various important biological processes in bacteria. The best-studied example is cyclic di-GMP (c-di-GMP). Known since the late 1980s, it is now recognized as a near-ubiquitous second messenger that coordinates diverse aspects of bacterial growth and behaviour, including motility, virulence, biofilm formation and cell cycle progression. In this Review, we discuss important new insights that have been gained into the molecular principles of c-di-GMP synthesis and degradation, which are mediated by diguanylate cyclases and c-di-GMP-specific phosphodiesterases, respectively, and the cellular functions that are exerted by c-di-GMP-binding effectors and their diverse targets...
February 6, 2017: Nature Reviews. Microbiology
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