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https://www.readbyqxmd.com/read/29160561/can-overnight-stenting-be-safely-eliminated-following-a-pharyngeal-flap-a-matched-comparison-study
#1
Andre M Wineland, Jareen Meinzen-Derr, Paul Willging
OBJECTIVE: Determine if overnight stenting is warranted after pharyngeal flap for management of velopharyngeal insufficiency (VPI) in pediatric patients METHODS: This is a retrospective age-matched cohort study from a single tertiary pediatric facility. Patients who underwent a posterior pharyngeal flap for VPI from January 1, 2013, to December 31, 2016, were included. Two equal groups were constructed based on when their nasal stents were removed, that is, postoperative day (POD) 0 or POD 1...
November 21, 2017: Laryngoscope
https://www.readbyqxmd.com/read/29160153/voice-and-swallowing-dysfunction-in-neurofibromatosis-2
#2
Simon R Best, Julie Ahn, Shannon Langmead, Vaninder Dhillon, Alexander T Hillel, Lee M Akst, Jaishri O Blakeley
Objective Neurofibromatosis 2 (NF2) is a neuro-oncologic condition that presents with bilateral vestibular schwannomas of the cerebellopontine angle (CPA). Voice and swallowing impairment can occur from direct involvement or compression of the vagus nerve or as the result of surgical excision of CPA tumors. The objectives in this study are to (1) assess the prevalence of voice and swallowing impairments and (2) analyze the effects of vagal dysfunction in patients with NF2. Study Design Cross-sectional. Setting Academic tertiary care center...
November 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29150379/changes-in-maxillofacial-morphology-and-velopharyngeal-function-with-two-stage-maxillary-distraction-mandibular-setback-surgery-in-patients-with-cleft-lip-and-palate
#3
T Susami, Y Mori, K Ohkubo, M Takahashi, Y Hirano, H Saijo, T Takato
Maxillary distraction is increasingly used for the correction of severe maxillary retrusion in patients with cleft lip and palate. However, control of the maxillary movement is difficult, and the need to wear visible distractors for a long period of time causes psychosocial problems. A two-stage surgical approach consisting of maxillary distraction and mandibular setback was developed to overcome these problems. In this study, changes in maxillofacial morphology and velopharyngeal function were examined in 22 patients with cleft lip and palate who underwent this two-stage approach...
November 14, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29146179/soft-palate-reconstruction-after-radionecrosis-combined-anterolateral-thigh-adipofascial-and-nasoseptal-flaps
#4
Joseph Zenga, Jeffrey D Sharon, Jennifer Gross, Jay Gantz, Patrik Pipkorn
Although radiation-based treatment for nasopharyngeal cancer may achieve excellent long term oncologic results, late effects of therapy may lead to soft tissue radionecrosis and velopharyngeal insufficiency (VPI). Repair of these oro- and nasopharyngeal defects presents a complex reconstructive challenge. We present a case of a long-term survivor treated with chemoradiotherapy for nasopharyngeal cancer who developed progressive dysphagia, velopharyngeal insufficiency, and radionecrosis of the nasopharynx and soft palate, leading to tracheostomy and gastrostomy tube dependence...
November 13, 2017: Auris, Nasus, Larynx
https://www.readbyqxmd.com/read/29135733/treatment-of-maxillary-hypoplasia-in-cleft-lip-and-palate-segmental-distraction-osteogenesis-with-hyrax-device
#5
Rodrigo Fariña, Alejandro Diaz, Roberto Pantoja, Carolina Bidart
The objective of this work is to describe a segmental maxillary distraction osteogenesis (SDO) with segmental Lefort I with an inexpensive device.Four patients who presented severe class III and maxillary hypoplasia due to cleft lip and palate sequel were treated. A SDO was performed using a dental-anchored Hyrax device, achieving enlargement of the upper jaw without altering speech, with adequate and stable occlusion. Dental implants in a new formed bone were installed.The authors can conclude that SDO is a good treatment alternative for patients with maxillary hypoplasia...
November 9, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29084117/a-review-of-randomized-controlled-trials-in-cleft-and-craniofacial-surgery
#6
Jonathan M Bekisz, Elise Fryml, Roberto L Flores
This study presents a systematic review of randomized controlled trials (RCTs) in cleft and craniofacial surgery. All studies reporting on RCTs in cleft and craniofacial surgery were identified on PubMed using the search terms "cleft," "velopharyngeal insufficiency," "velopharyngeal dysfunction," "nasoalveolar molding," "gingivoperiosteoplasty," "Pierre Robin sequence," "craniofacial," "craniosynostosis," "craniofacial microsomia," "hemifacial microsomia," "hypertelorism," "Le Fort," "monobloc," "distraction osteogenesis," "Treacher Collins," and "Goldenhar...
October 27, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29082563/magnetic-resonance-imaging-of-the-upper-airway-in-patients-with-quadriplegia-and-obstructive-sleep-apnea
#7
Fergal J O'donoghue, Hailey Meaklim, Lynne Bilston, Alice Hatt, Alan Connelly, Graeme Jackson, Shawna Farquharson, Kate Sutherland, Peter A Cistulli, Douglas J Brown, David J Berlowitz
The aim of this study was to investigate upper airway anatomy in quadriplegics with obstructive sleep apnea. Fifty subjects were recruited from three hospitals in Australia: people with quadriplegia due to spinal cord injury and obstructive sleep apnea (n = 11), able-bodied people with obstructive sleep apnea (n = 18), and healthy, able-bodied controls (n = 19). All underwent 3-Tesla magnetic resonance imaging of their upper airway. A subgroup (n = 34) received a topical vasoconstrictor, phenylephrine and post-phenylephrine magnetic resonance imaging...
October 30, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/29077684/nasopharyngoscopic-analyses-through-anterior-maxillary-distraction-osteogenesis-for-adolescent-patients-with-cleft-palate
#8
Yoshimichi Imai, Tetsu Nakajo, Kazuaki Nishimura, Hiroyuki Kanzaki, Takayoshi Daimaruya, Akimitsu Satoh, Kaoru Igarashi, Masahiro Tachi
Anterior maxillary distraction osteogenesis (AMDO) is a novel technique for correcting hypoplastic maxilla by sagittal expansion of the maxilla. Recent reports suggest that AMDO does not have an effect on fragile velopharyngeal function in patients with cleft palate. Furthermore, no studies have evaluated the impact of AMDO on velopharyngeal function.We adopted AMDO to correct severe hypoplastic maxilla in adolescent patients with cleft palate and evaluated its impact on velopharyngeal space and function in 8 patients aged 12 to 21 years who underwent AMDO from 2006 to 2014...
October 26, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29069271/intensive-treatment-of-speech-disorders-in-robin-sequence-a-case-report
#9
Maria Daniela Borro Pinto, Maria Inês Pegoraro-Krook, Laura Katarine Félix de Andrade, Ana Paula Carvalho Correa, Linda Iris Rosa-Lugo, Jeniffer de Cássia Rillo Dutka
PURPOSE: To describe the speech of a patient with Pierre Robin Sequence (PRS) and severe speech disorders before and after participating in an Intensive Speech Therapy Program (ISTP). METHODS: The ISTP consisted of two daily sessions of therapy over a 36-week period, resulting in a total of 360 therapy sessions. The sessions included the phases of establishment, generalization, and maintenance. A combination of strategies, such as modified contrast therapy and speech sound perception training, were used to elicit adequate place of articulation...
October 23, 2017: CoDAS
https://www.readbyqxmd.com/read/29068965/single-stage-repair-of-palatal-fistula-and-velopharyngeal-incompetence-by-the-new-l-flap
#10
Mohammad Waheed El-Anwar, Ezzeddin Elsheikh, Sherif Askar
OBJECTIVE: To describe and assess the results of use of the new L-shaped posterior pharyngeal flap for repair of both palatal fistula and velopharyngeal incompetence. METHODS: This study included 10 patients who were diagnosed to have soft palate fistula and persistent velopharyngeal insufficiency (VPI). L-shaped superiorly based pharyngeal flap was harvested from oropharynx and inserted into the soft palate closing the fistula after fistula trimming. The palatal part of the flap (transverse limb) was spread 1 cm horizontally and 1 cm in the anteroposterior direction in soft palate at fistula site closing it without tension...
October 24, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29053517/total-palatal-mobilization-and-multilamellar-suturing-technique-improves-outcome-for-palatal-fistula-repair
#11
Ahmed Elsherbiny, John H Grant
BACKGROUNDS: The success rate of the surgical repair of palatal fistula after palatoplasty is often unsatisfactory. This study is a review of 15 years of single surgeon's experience with the evolution of a reliable surgical technique with high success rate. METHODS: This is a retrospective chart review of consecutive cleft cases undergoing repair of palatal fistula from 2000 to 2015. The study included 37 consecutive fistula repair cases with wide elevation and mobilization of the palatal tissues and nasal and oral layer repair...
December 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29032918/adults-with-22q11-2-deletion-syndrome-have-a-different-velopharyngeal-anatomy-with-predisposition-to-velopharyngeal-insufficiency
#12
Charles Filip, Davide Impieri, Ingegerd Aagenæs, Corstiaan Breugem, Hans Erik Høgevold, Tone Særvold, Ragnhild Aukner, Kari Lima, Kim Tønseth, Tore G Abrahamsen
AIM: To find out if subjects with 22q11.2 deletion syndrome (DS) have a different velopharyngeal anatomy which could cause velopharyngeal insufficiency (VPI). METHODS: A prospective study of 16 subjects >16 years of age with 22q11.2 DS, without overt cleft palate and without previous VPI surgery, and 48 healthy controls >18 years of age were included in the study. Speech was recorded and scored blindly by two independent senior speech therapists. All 64 individuals had MRI scans, which were analyzed blindly by a consultant radiologist...
September 22, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29017844/buccinator-myomucosal-flap-for-the-treatment-of-velopharyngeal-insufficiency-in-patients-with-cleft-palate-and-or-lip
#13
Rafael Denadai, Anelise Sabbag, Cassio Eduardo Raposo Amaral, João Carlos Pereira Filho, Mirian Hideko Nagae, Cesar Augusto Raposo Amaral
INTRODUCTION: The interpretation of the speech results obtained with the buccinator myomucosal flap in the treatment of velopharyngeal insufficiency in patients with cleft palate has been limited by the restriction in the number of patients and the time of postoperative follow-up. OBJECTIVE: To evaluate the effect of the buccinator myomucosal flap on speech hypernasality in the treatment of patients with cleft palate and velopharyngeal insufficiency. METHODS: Patients with repaired cleft palate (± lip) who were submitted to surgical correction of velopharyngeal insufficiency using the bilateral buccinator myomucosal flap were assessed...
September 12, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29016863/a-tubb6-mutation-is-associated-with-autosomal-dominant-non-progressive-congenital-facial-palsy-bilateral-ptosis-and-velopharyngeal-dysfunction
#14
Walid Fazeli, Peter Herkenrath, Barbara Stiller, Antje Neugebauer, Julia Fricke, Ruth Lang-Roth, Gudrun Nürnberg, Michaela Thoenes, Jutta Becker, Janine Altmüller, Alexander E Volk, Christian Kubisch, Raoul Heller
Congenital cranial dysinnervation disorders (CCDDs) comprise a heterogeneous spectrum of diseases characterized by congenital, non-progressive impairment of eye, eyelid and/or facial movements including Möbius syndrome, Duane retraction syndrome, congenital ptosis, and congenital fibrosis of the extraocular muscles. Over the last 20 years, several CCDDs have been identified as neurodevelopmental disorders that are caused by mutations of genes involved in brain and cranial nerve development, e.g. KIF21A and TUBB3 that each plays a pivotal role for microtubule function...
October 15, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28990258/baseline-connectome-modular-abnormalities-in-the-childhood-phase-of-a-longitudinal-study-on-individuals-with-chromosome-22q11-2-deletion-syndrome
#15
Liang Zhan, Lisanne M Jenkins, Aifeng Zhang, Giorgio Conte, Angus Forbes, Danielle Harvey, Kathleen Angkustsiri, Naomi J Goodrich-Hunsaker, Courtney Durdle, Aaron Lee, Cyndi Schumann, Owen Carmichael, Kristopher Kalish, Alex D Leow, Tony J Simon
Occurring in at least 1 in 3,000 live births, chromosome 22q11.2 deletion syndrome (22q11DS) produces a complex phenotype that includes a constellation of medical complications such as congenital cardiac defects, immune deficiency, velopharyngeal dysfunction, and characteristic facial dysmorphic features. There is also an increased incidence of psychiatric diagnosis, especially intellectual disability and ADHD in childhood, lifelong anxiety, and a strikingly high rate of schizophrenia spectrum disorders, which occur in around 30% of adults with 22q11DS...
October 8, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28983420/velopharyngeal-dystonia-an-unusual-focal-task-specific-dystonia
#16
Amar S Patel, Lucian Sulica, Steven J Frucht
BACKGROUND: Velopharyngeal dysfunction produces a nasal speech pattern because of the inability to close the nasal airway during speech, most often associated with anatomical abnormalities of the palate. CASE REPORT: We describe two cases of possible velopharyngeal dystonia, a task-specific movement disorder causing a speech pattern similar to velopharyngeal dysfunction. Both patients experienced treatment response with anticholinergic medication. DISCUSSION: Dystonia affecting speech via involvement of the pharyngeal musculature may be an unrecognized etiology of voice disorders...
2017: Tremor and Other Hyperkinetic Movements
https://www.readbyqxmd.com/read/28979573/prosthodontic-rehabilitation-of-arabic-speaking-individuals-with-velopharyngeal-incompetence-a-preliminary-study
#17
Abdel Rahim M Bibars, Firas S D Alfwaress, Abed Al-Hadi Hamasha, Zeid A Al-Hourani, Khader Almhdawi
BACKGROUND: Hypernasality is a frequently encountered problem in the speech of individuals with velopharyngeal incompetence. The use of palatal lift appliance (PLA) is the main treatment option for correction of velopharyngeal incompetence. The literature on the outcomes of using prosthetics treatment for Arabic speaking patients is scarce. OBJECTIVE: The aim of this study was to investigate the effect of using PLA on hypernasality of Arabic speaking patients with velopharyngeal incompetence...
2017: Open Dentistry Journal
https://www.readbyqxmd.com/read/28947808/airway-changes-after-cleft-orthognathic-surgery-evaluated-by-three-dimensional-computed-tomography-and-overnight-polysomnographic-study
#18
Chun-Shin Chang, Christopher Glenn Wallace, Yen-Chang Hsiao, Yuh-Jia Hsieh, Yi-Chin Wang, Ning-Hung Chen, Yu-Fang Liao, Eric Jen-Wein Liou, Philip Kuo-Ting Chen, Jyh-Ping Chen, Yu-Ray Chen
Cleft lip and palate is the most common congenital craniofacial anomaly. Up to 60% of these patients will benefit from cleft orthognathic surgery, which consists primarily of maxillary advancement and mandibular setback to address midface retrusion and relative mandibular protrusion, respectively. It is believed that maxillary advancement can enlarge the airway whilst mandibular setback can reduce the airway, but this has not previously been quantified for cleft patients undergoing orthognathic surgery. This unique longitudinal prospective study of 18 patients was conducted between April 2013 and July 2016...
September 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28931196/endoscopy-assisted-coblation-for-nasopharyngeal-stenosis-a-report-of-2-cases
#19
Omer Karakoc, Bahtiyar Polat, M Timur Akcam, Mustafa Gerek
Acquired nasopharyngeal stenosis, the standard treatments for which carry a high risk of restenosis, is an uncommon complication of both velopharyngeal surgery and radiotherapy to the nasopharynx. We present the cases of 2 men, aged 41 and 52 years, who underwent surgical treatment for nasopharyngeal stenosis with endoscopy-assisted Coblation. The two surgeries lasted 23 and 18 minutes, respectively. Neither patient experienced any surgical complication, and a nasopharyngeal stent was not needed in either case...
September 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28895429/effectiveness-of-adenotonsillectomy-and-risk-of-velopharyngeal-insufficiency-in-children-with-prader-willi-syndrome
#20
COMPARATIVE STUDY
Reema Padia, Harlan Muntz, Kathleen Pfeffer, Jeremy Meier
OBJECTIVES: (1) Review effectiveness of adenotonsillectomy (T&A) for obstructive sleep apnea (OSA) in children with Prader-Willi syndrome (PW). (2) Examine the incidence of velopharyngeal insufficiency (VPI) after T&A in this population. (3) Compare outcomes of T&A in PW and Trisomy 21 (T21) patients. METHODS: Outcomes after T&A in a PW cohort were retrospectively reviewed and compared to those in patients with T21. RESULTS: The study cohort included 22 PW patients...
November 2017: Annals of Otology, Rhinology, and Laryngology
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