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colorectal and laparoscopic surgery

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https://www.readbyqxmd.com/read/28213593/randomised-double-blind-parallel-group-placebo-controlled-study-to-evaluate-the-analgesic-efficacy-and-safety-of-vvz-149-injections-for-postoperative-pain-following-laparoscopic-colorectal-surgery
#1
Srdjan S Nedeljkovic, Darin J Correll, Xiaodong Bao, Natacha Zamor, Jose L Zeballos, Yi Zhang, Mark J Young, Johanna Ledley, Jessica Sorace, Kristen Eng, Carlyle P Hamsher, Rajivan Maniam, Jonathan W Chin, Becky Tsui, Sunyoung Cho, Doo H Lee
INTRODUCTION: In spite of advances in understanding and technology, postoperative pain remains poorly treated for a significant number of patients. In colorectal surgery, the need for developing novel analgesics is especially important. Patients after bowel surgery are assessed for rapid return of bowel function and opioids worsen ileus, nausea and constipation. We describe a prospective, double-blind, parallel group, placebo-controlled randomised controlled trial testing the hypothesis that a novel analgesic drug, VVZ -149, is safe and effective in improving pain compared with providing opioid analgesia alone among adults undergoing laparoscopic colorectal surgery...
February 17, 2017: BMJ Open
https://www.readbyqxmd.com/read/28208110/trocar-site-evisceration-of-the-vermiform-appendix-following-laparoscopic-sigmoid-colectomy-a-case-report
#2
Jagdeep Singh Bhangu, Ruth Exner, Thomas Bachleitner-Hofmann
INTRODUCTION: There is an ongoing debate whether prophylactic drainage or incidental appendectomy should be performed in patients undergoing colorectal surgery. On the other hand, it has been shown that the placement of drains through former trocar sites as well as the use of large (≥10mm) trocars, incomplete fascial closure or closed laparoscopy technique all predispose for the occurrence of trocar site hernias. PRESENTATION OF CASE: We report the case of a 59-year-old male patient who underwent laparoscopic sigmoid colectomy with primary anastomosis for recurrent sigmoid diverticulitis...
February 1, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28207849/inhibition-of-peritoneal-dissemination-of-colon-cancer-by-hyperthermic-co2-insufflation-a-novel-approach-to-prevent-intraperitoneal-tumor-spread
#3
Yuanfei Peng, Hua Yang, Qing Ye, Houming Zhou, Minhua Zheng, Yinghong Shi
BACKGROUND: The increasing use of laparoscopic surgery for advanced gastrointestinal cancer raises concerns about intra-peritoneal tumor spread. Prevention of peritoneal dissemination is extremely important but a preventive modality is lacking. The aim of this study was to examine a novel approach (hyperthermic CO2 insufflation, HT-CO2) for preventing peritoneal dissemination during laparoscopic surgery. METHODS: A peritoneal dissemination model was established in Balb/c nu/nu mice by intraperitoneal injection of human colon cancer cells (SW1116, 1×106)...
2017: PloS One
https://www.readbyqxmd.com/read/28207436/multicenter-observational-study-of-adhesion-formation-after-open-and-laparoscopic-surgery-for-colorectal-cancer
#4
Martijn W J Stommel, Richard P G Ten Broek, Chema Strik, Gerrit D Slooter, Cornelis Verhoef, Dirk J Grünhagen, Peter van Duijvendijk, Marc H A Bemelmans, Marcel den Dulk, Colin Sietses, Tjarda N T van Heek, Peter B van den Boezem, Johannes H W de Wilt, Harry van Goor
OBJECTIVE: The aim of this study was to compare adhesion formation after laparoscopic and open colorectal cancer resection. SUMMARY OF BACKGROUND DATA: After colorectal surgery, most patients develop adhesions, with a high burden of complications. Laparoscopy seems to reduce adhesion formation, but evidence is poor. Trials comparing open- and laparoscopic colorectal surgery have never assessed adhesion formation. METHODS: Data on adhesions were gathered during resection of colorectal liver metastases...
February 15, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28205033/midterm-follow-up-of-a-randomized-trial-of-open-surgery-versus-laparoscopic-surgery-in-elderly-patients-with-colorectal-cancer
#5
Atsushi Ishibe, Mitsuyoshi Ota, Shoichi Fujii, Yusuke Suwa, Shinsuke Suzuki, Hirokazu Suwa, Masashi Momiyama, Jun Watanabe, Kazuteru Watanabe, Masataka Taguri, Chikara Kunisaki, Itaru Endo
BACKGROUND: Laparoscopic surgery has been widely accepted for the treatment of colorectal cancer; however, long-term outcomes in elderly patients remain controversial. The midterm results of a randomized trial comparing open surgery with laparoscopic surgery in elderly patients with colorectal cancer are presented. METHODS: This was a randomized trial comparing open surgery with laparoscopic surgery in elderly patients with colorectal cancer. The primary outcome was complication rate, and secondary outcomes included 3-year recurrence-free survival and overall survival...
February 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28199016/systematic-review-of-the-feasibility-of-laparoscopic-reoperation-for-early-postoperative-complications-following-colorectal-surgery
#6
REVIEW
D B Wright, C E Koh, M J Solomon
BACKGROUND: Returning to the operating theatre for management of early postoperative complications after colorectal surgery is an important key performance indicator. Laparoscopic surgery has benefits that may be useful in surgical emergencies. This study explored the evidence for the advantages of laparoscopic reoperation. METHODS: A systematic review was performed to identify publications reporting the outcomes of laparoscopy as a mode of reoperation for the management of early postoperative complications of colorectal surgery...
March 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28177995/incidence-risk-factors-and-trends-of-motor-peripheral-nerve-injury-after-colorectal-surgery-analysis-of-the-national-surgical-quality-improvement-program-database
#7
Mohammed H Al-Temimi, Bindupriya Chandrasekaran, Michael J Phelan, Alessio Pigazzi, Steven D Mills, Michael J Stamos, Joseph C Carmichael
BACKGROUND: Motor peripheral nerve injury is a rare but serious event after colorectal surgery, and a nationwide study of this complication is lacking. OBJECTIVE: The purpose of this study was to report the incidence, trends, and risk factors of motor peripheral nerve injury during colorectal surgery. DESIGN: The National Surgical Quality Improvement Program database was surveyed for motor peripheral nerve injury complicating colorectal procedures...
March 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28173934/laparoscopic-hepatectomy-significantly-shortens-the-time-to-postoperative-chemotherapy-in-patients-undergoing-major-hepatectomies
#8
Nsehniitooh Mbah, Steven C Agle, Prejesh Philips, Michael E Egger, Charles R Scoggins, Kelly M McMasters, Robert C G Martin
BACKGROUND: The benefit of adjuvant chemotherapy occurs with early initiation, but is commonly delayed due to postoperative complications. Minimally invasive surgery is proven to significantly reduce complications and hospital length of stay. This study compares open versus laparoscopic liver resection in patients requiring adjuvant chemotherapy. METHODS: 120 consecutive patients with metastatic colorectal liver cancer who underwent liver resection between 2007 through 2012 were reviewed from an IRB prospective database...
January 30, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28162676/-428-a-randomized-double-blind-parallel-group-placebo-controlled-study-to-evaluate-the-analgesic-efficacy-and-safety-of-vvz-149-injections-for-post-operative-pain-following-laparoscopic-colorectal-surgery
#9
S Nedeljkovic, D Correll, X Bao, N Zamor, J Zeballos, Y Zhang, M Young, J Ledley, J Sorace, K Eng, C Hamsher, R Maniam, J Chin, B Tsui, S Cho, D Lee
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28157065/complete-mesocolic-excision-an-assessment-of-feasibility-and-outcome
#10
Claus Anders Bertelsen
Surgery is the most important factor for radical treatment of colon cancer, and the long-term prognosis can be improved by improving the surgical treatment without increased risk of perioperative mortality. Complete mesocolic excision (CME), in which more extensive lymph node (LN) dissection is performed, has been shown in single-centre studies with historical controls to be associated with better oncological outcome. However, better evidence is needed. The main purpose of this PhD thesis was to investigate whether CME could be implemented in a colorectal surgical department in Denmark, whether more extensive dissection could demonstrate LN metastases outside the mesocolon, and to demonstrate a possible association between CME and improved oncological results without increased risk of perioperative mortality...
February 2017: Danish Medical Journal
https://www.readbyqxmd.com/read/28144830/cost-effective-personalized-3d-printed-liver-model-for-preoperative-planning-before-laparoscopic-liver-hemihepatectomy-for-colorectal-cancer-metastases
#11
Jan Sylwester Witowski, Michał Pędziwiatr, Piotr Major, Andrzej Budzyński
PURPOSE: Three-dimensional (3D) printing for preoperative planning has been intensively developed in the recent years. However, the implementation of these solutions in hospitals is still difficult due to high costs, extremely expensive industrial-grade printers, and software that is difficult to obtain and learn along with a lack of a defined process. This paper presents a cost-effective technique of preparing 3D-printed liver models that preserves the shape and all of the structures, including the vessels and the tumor, which in the present case is colorectal liver metastasis...
January 31, 2017: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/28133026/-treatment-using-self-expandable-metal-stent-for-ileus-associated-with-colorectal-cancer-in-our-hospital
#12
Shunsuke Imanishi, Kazuma Yamazaki, Toshihide Komatsubara, Masaaki Kodama, Satoru Kondo
From September 2013 to February 2015, 14 patients with ileus associated with colorectal cancer underwent surgeryafter applying a self-expandable metal stent in our department. Twelve were left-side colon ileus patients and 2 were right-side colon ileus patients. The technical success rate of the stent insertion was 100%. One patient experienced complications(stent occlusion). All patients were able to eat, and 9 of them were able to leave the hospital temporarilybefore the operation. All patients with left-side colon ileus had their oral-side intestine evaluated before the operation...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28130643/safety-of-laparoscopic-surgery-for-colorectal-cancer-in-patients-over-80%C3%A2-years-old-a-propensity-score-matching-study
#13
Mai Shiga, Hiromichi Maeda, Koji Oba, Ken Okamoto, Tsutomu Namikawa, Kazune Fujisawa, Keiichiro Yokota, Michiya Kobayashi, Kazuhiro Hanazaki
PURPOSES: To establish the safety of laparoscopic-assisted colorectal resection for colorectal cancer in elderly patients aged ≥80 years. METHODS: Data were obtained from a chart review of patients who underwent colorectal cancer resection between 2009 and 2014 in Kochi Medical School. The effect of patient age on the extent of lymph node dissection and operative safety was assessed by comparing the short-term results of elderly patients with those of younger patients after propensity score matching...
January 27, 2017: Surgery Today
https://www.readbyqxmd.com/read/28126972/intravenous-lignocaine-infusion-facilitates-acute-rehabilitation-after-laparoscopic-colectomy-in-the-chinese-patients
#14
M Wh Lee, D Yl Or, A Cf Tsang, D Ck Ng, P P Chen, M Hy Cheung, R Sk Li, H T Leong
INTRODUCTION: Intravenous infusion of lignocaine has emerged in recent years as a feasible, cost-effective, and safe method to provide postoperative analgesia. There is, however, no literature about this peri-operative pain control modality in Chinese patients. This study aimed to determine whether peri-operative intravenous lignocaine safely reduces postoperative pain, shortens postoperative ileus, and reduces the length of hospital stay in laparoscopic colorectal surgery. METHODS: Between September 2012 and May 2015, 16 patients who underwent elective laparoscopic resection of colorectal cancer and received a 1% lignocaine infusion for 24 hours postoperatively were studied...
January 27, 2017: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/28121916/totally-laparoscopic-anatomical-liver-resection-for-centrally-located-tumors-a-single-center-experience
#15
Wan-Joon Kim, Ki-Hun Kim, Min-Ho Shin, Young-In Yoon, Sung-Gyu Lee
Laparoscopic major hepatectomy is a common procedure that has been reported frequently; however, laparoscopic resection of centrally located tumors involving segments 4, 5, and 8 remains a technically difficult procedure because it requires 2 transection planes and dissection of numerous branches of the hepatic vein and glissonean capsule compared to hemi-hepatectomy. Here, we present 7 cases of totally laparoscopic right anterior sectionectomy (Lap-RAS) and 3 cases of totally laparoscopic central bisectionectomy (Lap-CBS)...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28099070/laparoscopic-rectal-dissection-assisted-by-transanal-endoluminal-videoendoscopy-through-a-blunt-tip-trocar
#16
Emanuele Asti, Andrea Lovece, Luigi Bonavina
BACKGROUND AND AIMS: Laparoscopic resection is a well-established approach for colorectal cancer surgery. In patients with rectal cancer treated by neoadjuvant chemoradiotherapy, it may be difficult to identify a clear safety margin for endostapling and subsequent anastomosis. We designed an innovative technical approach to assist colorectal anastomosis in these patients. TECHNIQUE: A four-trocar laparoscopic approach is used. After exploration of the abdominal cavity, the left colic flexure is completely mobilized...
January 18, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28096324/totally-laparoscopic-liver-resection-for-colorectal-metastasis-located-in-segment-7-in-a-patient-with-situs-inversus-totalis
#17
Antonio Giuliani, Paolo Bianco, Germano Guerra, Aldo Rocca, Fulvio Calise
Situs inversus totalis (SIT) is a congenital condition consisting of a mirror image of transposition of the abdominal and thoracic organs occurring in about 1:5000 to 1:10 000 adults. We report on a 60-year-old male with a single colorectal liver metastasis in the Segment 7. The patients underwent a totally laparoscopic sub-segmentectomy. Intraoperative approach on a reverse posterior segment was difficult because of left-sided position of the liver. Postoperative course was uneventful and the patient was discharged after 5 days...
January 17, 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28091841/transumbilical-abdominal-incision-for-laparoscopic-colorectal-surgery-does-not-increase-the-risk-of-postoperative-surgical-site-infection
#18
Mizunori Yaegashi, Koki Otsuka, Toshimoto Kimura, Masanori Hakozaki, Megumu Kamishima, Tomoki Hatanaka, Kei Sato, Hitoshi Fujii, Teppei Matsuo, Akira Sasaki
PURPOSE: Besides antibiotic prophylaxis, antiseptic skin preparation is an important measure to prevent surgical site infection (SSI). No reports have detailed the relationship between SSI and umbilical microflora following laparoscopic colorectal cancer with a transumbilical longitudinal incision. METHODS: Risk factors and the rate of SSI were investigated in 453 patients who underwent laparoscopic colorectal resection over a 3-year period. Microbiological samples were collected from the umbilicus and SSI areas...
January 13, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28078466/does-stoma-site-specimen-extraction-increase-postoperative-ileostomy-complication-rates
#19
Wanglin Li, Cigdem Benlice, Luca Stocchi, Hermann Kessler, Emre Gorgun, Meagan Costedio
BACKGROUND: Minimizing incisions has the potential to decrease hernia formation and wound complications following laparoscopic surgery. It is currently unknown if using the stoma site for specimen extraction affects outcomes. This study aims to evaluate the impact of stoma site extraction on postoperative complication rates in laparoscopic colorectal surgery. METHODS: After IRB approval, a retrospective comparative review of 738 consecutive patients (405 M) who underwent laparoscopic colorectal surgery with ileostomy between January 2008 and December 2014 was performed...
January 11, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28070329/mastering-minimally-invasive-esophagectomy-requires-a-mentor-experience-of-a-personal-mentorship
#20
Miguel A Cuesta, Nicole van der Wielen, Jennifer Straatman, Donald L van der Peet
Since the first laparoscopic procedure, there has been an steady increase in advanced minimally invasive surgery. These procedures include oncological colorectal, hepatobiliary and upper gastrointestinal surgery. Implementation of these procedures requires different and new skills for the surgeons who wish to perform these procedures. To accomplish this surgical teaching program, a mentorship seems the most ideal method to teach the apprentice surgeon these specific skills. At the VU medical center a teaching program for a minimally-invasive esophagectomy for esophageal cancer started in 2009...
January 2017: Annals of Medicine and Surgery
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