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https://www.readbyqxmd.com/read/28227990/using-computational-phantoms-to-improve-delivery-of-tumor-treating-fields-ttfields-to-patients
#1
Ze'ev Bomzon, Hadas Sara Hershkovich, Noa Urman, Aafia Chaudhry, Dario Garcia-Carracedo, Anders R Korshoej, Uri Weinberg, Cornelia Wenger, Pedro Miranda, Yoram Wasserman, Eilon D Kirson, Yoram, Ze'ev Bomzon, Hadas Sara Hershkovich, Noa Urman, Aafia Chaudhry, Dario Garcia-Carracedo, Anders R Korshoej, Uri Weinberg, Cornelia Wenger, Pedro Miranda, Yoram Wasserman, Eilon D Kirson, Yoram, Uri Weinberg, Cornelia Wenger, Noa Urman, Hadas Sara Hershkovich, Yoram Wasserman, Anders R Korshoej, Eilon D Kirson, Dario Garcia-Carracedo, Pedro Miranda, Aafia Chaudhry, Zeev Bomzon, Yoram
This paper reviews the state-of-the-art in simulation-based studies of Tumor Treating Fields (TTFields) and highlights major aspects of TTFields in which simulation-based studies could affect clinical outcomes. A major challenge is how to simulate multiple scenarios rapidly for TTFields delivery. Overcoming this challenge will enable a better understanding of how TTFields distribution is correlated with disease progression, leading to better transducer array designs and field optimization procedures, ultimately improving patient outcomes...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227957/bidirectional-peripheral-nerve-interface-and-applications
#2
Nitish V Thakor, Qihong Wang, Elliot Greenwald, Nitish V Thakor, Qihong Wang, Elliot Greenwald, Elliot Greenwald, Nitish V Thakor, Qihong Wang
Peripheral nerves, due to their small size and complex innervation to organs and complex physiology, pose particularly significant challenges towards interfacing electrodes and electronics to enable neuromodulation. Here, we present a review of the technology for building such interface, including recording and stimulating electrodes and low power electronics, as well as powering. Of particular advantage to building a miniature implanted device is a "bidirectional" system that both senses from the nerves or surrogate organs and stimulates the nerves to affect the organ function...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227884/bone-composition-and-healing-open-electromagnetic-and-biomechanical-problems
#3
Peter Biggane, Xavier Jackson, Ara Nazarian, Peter Biggane, Xavier Jackson, Ara Nazarian, Ara Nazarian, Peter Biggane, Xavier Jackson
In this paper, we present a review of some electromagnetic interactions in bone matter. Special attention is paid to pulsed electromagnetic therapy, which is potentially a promising therapeutic method for bone healing. We review and compare existing setups and their applications.
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227482/assessing-app-quality-through-expert-peer-review-a-case-study-from-the-gray-matters-study
#4
Phillip J Hartin, Ian Cleland, Chris D Nugent, Sally I McClean, JoAnn Tschanz, Christine Clark, Maria C Norton, Phillip J Hartin, Ian Cleland, Chris D Nugent, Sally I McClean, JoAnn Tschanz, Christine Clark, Maria C Norton, JoAnn Tschanz, Christine Clark, Ian Cleland, Maria C Norton, Sally I McClean, Chris D Nugent, Phillip J Hartin
Health apps focused on inciting behavior change are becoming increasingly popular. Nevertheless, many lack underlying evidence base, scientific credibility and have limited clinical effectiveness. It is therefore important that apps are well-informed, scientifically credible, peer reviewed and evidence based. This paper presents the use of the Mobile App Rating Scale (MARS) to assess the quality of the Grey Matters app, a cross platform app to deliver health education material and track behavior change across multi-domains with the aim of reducing the risk of developing Alzheimer's disease...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227020/spatial-temporal-forensic-analysis-of-mass-casualty-incidents-using-video-sequences
#5
Hao Dong, Juechen Yin, James Schafer, Aura Ganz, Hao Dong, Juechen Yin, James Schafer, Aura Ganz, Juechen Yin, Hao Dong, James Schafer, Aura Ganz
In this paper we introduce DIORAMA based forensic analysis of mass casualty incidents (MCI) using video sequences. The video sequences captured on site are automatically annotated by metadata, which includes the capture time and the camera location and viewing direction. Using a visual interface the MCI investigators can easily understand the availability of video clips in specific areas of interest, and efficiently review them. The video-based forensic analysis system will enable the MCI investigators to better understand the rescue operations and subsequently improve training procedures...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227018/using-constrained-information-entropy-to-detect-rare-adverse-drug-reactions-from-medical-forums
#6
Yi Zheng, Chaowang Lan, Hui Peng, Jinyan Li, Yi Zheng, Chaowang Lan, Hui Peng, Jinyan Li, Jinyan Li, Hui Peng, Chaowang Lan, Yi Zheng
Adverse drug reactions (ADRs) detection is critical to avoid malpractices yet challenging due to its uncertainty in pre-marketing review and the underreporting in post-marketing surveillance. To conquer this predicament, social media based ADRs detection methods have been proposed recently. However, existing researches are mostly co-occurrence based methods and face several issues, in particularly, leaving out the rare ADRs and unable to distinguish irrelevant ADRs. In this work, we introduce a constrained information entropy (CIE) method to solve these problems...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226990/validity-of-the-small-swine-model-for-human-electrical-safety-risks
#7
Michael A Brave, Dhanunjaya R Lakkireddy, Mark W Kroll, Dorin Panescu, Michael A Brave, Dhanunjaya R Lakkireddy, Mark W Kroll, Dorin Panescu, Dhanunjaya R Lakkireddy, Mark W Kroll, Dorin Panescu, Michael A Brave
Small swine are the most common model now used for electrical safety studies. Because of the significant anatomical and electrophysiological differences and the effect of animal size on the ventricular fibrillation (VF) threshold, there are concerns that these differences may exaggerate the risks of electrical devices to humans. We chose, as an illustrative and relevant example, swine studies of the TASER(®) conducted electrical weapon (CEW) as it has numerous published VF studies. We reviewed the published electrical swine safety studies for CEWs and compared them to finite element modeling studies, electrical safety standards, and epidemiological experience from field usage...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226989/a-novel-portable-low-cost-kinect-based-system-for-motion-analysis-in-neurological-diseases
#8
Joao Paulo Silva Cunha, Ana Patricia Rocha, Hugo Miguel Pereira Choupina, Jose Maria Fernandes, Maria Jose Rosas, Rui Vaz, Felix Achilles, Anna Mira Loesch, Christian Vollmar, Elisabeth Hartl, Soheyl Noachtar, Joao Paulo Silva Cunha, Ana Patricia Rocha, Hugo Miguel Pereira Choupina, Jose Maria Fernandes, Maria Jose Rosas, Rui Vaz, Felix Achilles, Anna Mira Loesch, Christian Vollmar, Elisabeth Hartl, Soheyl Noachtar, Christian Vollmar, Ana Patricia Rocha, Elisabeth Hartl, Rui Vaz, Hugo Miguel Pereira Choupina, Soheyl Noachtar, Felix Achilles, Anna Mira Loesch, Jose Maria Fernandes, Joao Paulo Silva Cunha, Maria Jose Rosas
Many neurological diseases, such as Parkinson's disease and epilepsy, can significantly impair the motor function of the patients, often leading to a dramatic loss of their quality of life. Human motion analysis is regarded as fundamental towards an early diagnosis and enhanced follow-up in this type of diseases. In this contribution, we present NeuroKinect, a novel system designed for motion analysis in neurological diseases. This system includes an RGB-D camera (Microsoft Kinect) and two integrated software applications, KiT (KinecTracker) and KiMA (Kinect Motion Analyzer)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226743/adaptive-higuchi-s-dimension-based-retinal-vessel-diameter-measurement
#9
Behzad Aliahmad, Dinesh K Kumar, Behzad Aliahmad, Dinesh K Kumar, Behzad Aliahmad, Dinesh K Kumar
This paper proposes the use of an adaptive model to measure the width of retinal vessels in fundus photographs. It is based on the hypothesis that the Higuchi's dimension of the cross-section is proportional to the vessel diameter. This approach does not require image segmentation and binarization of the vessels and therefore is suitable for machine based measurements. The model is developed using a synthetic image of the vessel of known diameter and added noise. As a first step, the vessel cross-section profiles were manually obtained and analyzed using Higuchi's fractal dimension method...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226713/automatic-workflow-for-narrow-band-laryngeal-video-stitching
#10
Sara Moccia, Veronica Penza, Gabriele Omodeo Vanone, Elena De Momi, Leonardo S Mattos, Sara Moccia, Veronica Penza, Gabriele Omodeo Vanone, Elena De Momi, Leonardo S Mattos, Elena De Momi, Leonardo S Mattos, Gabriele Omodeo Vanone, Veronica Penza, Sara Moccia
In narrow band (NB) laryngeal endoscopy, the clinician usually positions the endoscope near the tissue for a correct inspection of possible vascular pattern alterations, indicative of laryngeal malignancies. The video is usually reviewed many times to refine the diagnosis, resulting in loss of time since the salient frames of the video are mixed with blurred, noisy, and redundant frames caused by the endoscope movements. The aim of this work is to provide to the clinician a unique larynx panorama, obtained through an automatic frame selection strategy to discard non-informative frames...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226561/feasibility-of-unobstrusive-ambient-sensors-for-fall-detections-in-home-environment
#11
Qing Zhang, Mohan Karunanithi, Qing Zhang, Mohan Karunanithi, Mohan Karunanithi, Qing Zhang
Falls are the leading threats of death, injury and hospital admissions of seniors. About one third of seniors fall every year. Real time fall detection is thus critical to support independent livings of seniors by getting timely interventions from carers/family members. Recent years along with the IoT booming, many wearable sensor based fall detection systems have been developed. However privacy concerns or simply forgot-to-wear make wearable sensors not very accepted by seniors in a home environment seeking long term monitoring solutions...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226441/intelligent-hearing-aids-the-next-revolution
#12
Tao Zhang, Fred Mustiere, Christophe Micheyl, Tao Zhang, Fred Mustiere, Christophe Micheyl, Tao Zhang, Christophe Micheyl, Fred Mustiere
The first revolution in hearing aids came from nonlinear amplification, which allows better compensation for both soft and loud sounds. The second revolution stemmed from the introduction of digital signal processing, which allows better programmability and more sophisticated algorithms. The third revolution in hearing aids is wireless, which allows seamless connectivity between a pair of hearing aids and with more and more external devices. Each revolution has fundamentally transformed hearing aids and pushed the entire industry forward significantly...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226439/optical-imaging-of-functional-connectivity-at-the-bedside
#13
Joseph P Culver, Karla M Bergonzi, Adam E Eggebrecht, Andrew K Fishell, Jin-Moo Lee, Joseph P Culver, Karla M Bergonzi, Adam E Eggebrecht, Andrew K Fishell, Jin-Moo Lee, Andrew K Fishell, Joseph P Culver, Jin-Moo Lee, Karla M Bergonzi, Adam E Eggebrecht
High-density imaging arrays have improved the image quality of diffuse optical tomography (HD-DOT) methods for mapping brain functions. Development of resting state measures of functional connectivity provides a brain assay logistically compatible with bedside imaging in the clinic. In this paper we review these advances and demonstrate the sensitivity of HD-DOT to acute ischemic stroke.
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226437/exploring-spatiotemporal-dynamics-of-the-human-brain-by-multimodal-imaging
#14
Han Yuan, Jerzy Bodurka, Lei Ding, Han Yuan, Jerzy Bodurka, Lei Ding, Han Yuan, Lei Ding, Jerzy Bodurka
Functional magnetic resonance imaging (fMRI) studies utilizing measures of hemodynamic signal, such as the blood-oxygenation-level dependent (BOLD) signal, have discovered that resting-state brain activities are organized into multiple large-scale functional networks, coined as resting state networks (RSNs). However, an important limitation of the available fMRI studies is that hemodynamic signals only provide an indirect measure of neuronal activity and that the neurobiological basis of the fMRI RSNs is not clear...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226431/virtual-reality-applications-in-assessing-the-effect-of-anxiety-on-sensorimotor-integration-in-human-postural-control
#15
Christopher Widdowson, Jatin Ganhotra, Mohammed Faizal, Marissa Wilko, Saurin Parikh, Zainulabidin Adhami, Manuel E Hernandez, Christopher Widdowson, Jatin Ganhotra, Mohammed Faizal, Marissa Wilko, Saurin Parikh, Zainulabidin Adhami, Manuel E Hernandez, Marissa Wilko, Zainulabidin Adhami, Manuel E Hernandez, Saurin Parikh, Mohammed Faizal, Jatin Ganhotra, Christopher Widdowson
Falls are a leading cause of injury and mortality among adults over the age of 65 years. Given the strong relation between fear of falling and fall risk, identification of the mechanisms that underlie anxiety-related changes in postural control may pave the way to the development of novel therapeutic strategies aimed at reducing fall risk in older adults. First, we review potential mechanisms underlying anxiety-mediated changes in postural control in older adults with and without neurological conditions. We then present a system that allows for the simultaneous recording of neural, physiological, and behavioral data in an immersive virtual reality (VR) environment while implementing sensory and mechanical perturbations to evaluate alterations in sensorimotor integration under conditions with high postural threat...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226418/omalizumab-for-the-treatment-of-chronic-idiopathic-urticaria-systematic-review-of-the-literature
#16
Alessandro Tonacci, Lucia Billeci, Giovanni Pioggia, Michele Navarra, Sebastiano Gangemi
Omalizumab is recombinant humanized monoclonal antibody to immunoglobulin E. Guidelines for the treatment of chronic idiopathic urticaria (also known as chronic spontaneous urticaria) recommend the use of omalizumab as third-line therapy in addition to high doses of histamine receptor type 1 (H1 ) antihistamines when they are unsuccessful as first- and second-line therapy. We performed a systematic review of the literature to identify studies that evaluated the efficacy of omalizumab for the treatment of chronic idiopathic urticaria, both in controlled and real-world settings, to assess its potential role as a preferred therapy...
February 22, 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28226416/the-contribution-of-the-emergency-department-to-opioid-pain-reliever-misuse-and-diversion-a-critical-review
#17
REVIEW
Tatyana Lyapustina, Renan Castillo, Elise Omaki, Wendy Shields, Eileen McDonald, Richard Rothman, Andrea Gielen
Prescription opioid pain reliever (OPR) misuse and diversion is an important and growing public health problem in the United States that is responsible for significant morbidity and mortality. Emergency physicians are among the top prescribers of OPRs, yet the relative contribution of emergency department (ED) OPR prescriptions to the overall opioid abuse epidemic remains unclear. This study critically reviews seven peer-reviewed studies that specifically identified the ED as a source of OPRs. Of the OPRs prescribed in the ED, approximately 10% are associated with indicators of inappropriate prescribing, and approximately 42% may ultimately be misused; of the OPRs that are diverted, approximately 10% originate from an ED prescription...
February 22, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/28226406/what-do-we-know-about-older-former-carers-key-issues-and-themes
#18
Mary Larkin, Alisoun Milne
Despite a significant growth in the number older former family carers, they remain largely invisible in carer-related research and literature. To begin to address this deficit, a four-stage literature review was conducted to identify existing knowledge about older former carers. Narrative synthesis of the findings yielded five themes - the concept of 'older former carer', the legacies of caring, influences on the legacies of caring, conceptualising post-caring and support services for older former carers. Critical analysis of these findings suggests that existing evidence has a number of strengths...
February 22, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28226403/the-effect-of-peripheral-neuromodulation-on-pain-from-the-sacroiliac-joint-a-retrospective-cohort-study
#19
Teodor Goroszeniuk, Ashish Shetty, Rajesh Munglani, Dominic Hegarty, Arun Bhaskar
We report here a retrospective review of the longer-term results of peripheral neuromodulation in 12 patients with significant chronic sacroiliac joint pain who had previously failed multiple conservative and interventional pain therapies. To allow for the assessment of meaningful longer-term outcome, implants for all 12 patients had been in place for a minimum of 18 months to a maximum of 36 months prior to the formal review. Compared to the preimplantation baseline, the longer-term follow-up revealed a significant and sustained reduction in visual analog scale pain scores from 8...
February 22, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/28226384/-the-use-of-nudging-for-primary-prevention-a-review-and-perspectives-for-germany
#20
Mathias Krisam, Peter von Philipsborn, Björn Meder
Nudging as a means of influencing human behaviour has received increasing attention by policy makers, including those in the field of public health. Nudges are generally understood as specific aspects of a choice architecture that make certain behaviours more likely to occur without mandating them through binding rules, and without relying on economic incentives. Following the example of the United States and Great Britain, the German government has established a working group tasked with advising the federal government on the use of nudging and other behavioural interventions in policy making...
February 2017: Das Gesundheitswesen
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