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epinephrine in anaphylaxis

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https://www.readbyqxmd.com/read/29904820/food-induced-anaphylaxis-an-update
#1
REVIEW
Christopher P Parrish, Heidi Kim
PURPOSE OF REVIEW: This review aims to provide an update of recent advances in the epidemiology, clinical features and diagnosis, and management of food-induced anaphylaxis (FIA). RECENT FINDINGS: Food allergy prevalence and FIA rates continue to rise, but FIA fatalities are stable. Basophil and mast cell activation tests promise more accurate identification of food triggers. Oral, sublingual, and epicutaneous immunotherapy can desensitize a significant portion of subjects...
June 14, 2018: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/29791521/specific-questionnaire-detects-a-high-incidence-of-intra-operative-hypersensitivity-reactions
#2
Laila S Garro, Marcelo V Aun, Iracy Sílvia C Soares, Marisa R Ribeiro, Antônio A Motta, Jorge Kalil, Mariana C Castells, Maria José C Carmona, Pedro Giavina-Bianchi
OBJECTIVE: To assess the incidence of intra-operative immediate hypersensitivity reactions and anaphylaxis. METHODS: A cross-sectional observational study was conducted at the Department of Anesthesiology, University of São Paulo School of Medicine, Hospital das Clínicas, São Paulo, Brazil, from January to December 2010. We developed a specific questionnaire to be completed by anesthesiologists. This tool included questions about hypersensitivity reactions during anesthesia and provided treatments...
May 17, 2018: Clinics
https://www.readbyqxmd.com/read/29759531/biphasic-anaphylaxis-a-review-of-the-literature-and-implications-for-emergency-management
#3
REVIEW
Ali Pourmand, Chelsea Robinson, Wahab Syed, Maryann Mazer-Amirshahi
BACKGROUND: The biphasic reaction is a feared complication of anaphylaxis management in the emergency department (ED). The traditional recommended ED observation time is 4-6 h after complete resolution of symptoms for every anaphylaxis patient. However, there has been great controversy regarding whether this standard of care is evidence-based. METHODS: Articles were selected using a PubMed, MEDLINE search for the keywords "biphasic anaphylaxis", yielding 155 articles...
May 9, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29746901/epinephrine-auto-injectors-and-anaphylaxis-challenges-of-dose-depth-and-device
#4
REVIEW
Julie Brown
OBJECTIVES: 1. To review epinephrine dosing, site and route of administration, focusing on special populations (patients weighing less that 15 kg, and obese patients). 2. To discuss storage and delivery of epinephrine in pre-hospital and hospital settings. DATA SOURCES: Review of published literature. STUDY SELECTION: Relevancy. RESULTS: The recommended 0.01 mg/kg (max 0.3-0.5 mg) epinephrine dose in anaphylaxis is based on limited pharmacokinetic data in healthy volunteers...
May 7, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29723945/-are-natural-analgesic-products-safe-in-patients-with-allergy-to-non-steroidal-anti-inflammatory-drugs
#5
Iván Chérrez-Ojeda, Juan Carlos Calderón, Erick Calero, César Terán, Annia Chérrez
BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAID)-induced hypersensitivity reactions can be clinically apparent with asthma, rhinosinusitis, anaphylaxis or rash. Although natural anti-inflammatory products can have similar components, they are not subjected to rigorous quality control standards. CASE REPORT: The case is presented of a 22-year-old female with NSAID allergy who attended with facial and laryngeal angioedema associated with pruritus in eyelids and pharynx...
January 2018: Revista Alergia Mexico: Organo Oficial de la Sociedad Mexicana de Alergia e Inmunología, A.C
https://www.readbyqxmd.com/read/29718854/neurologic-manifestations-in-anaphylaxis-due-to-subcutaneous-allergy-immunotherapy-a-case-report
#6
Michelle Mangold, Mahboob Qureshi
RATIONALE: Life-threatening anaphylactic shock is a rare (1 in 1 million) but documented occurrence in response to subcutaneous immunotherapy. Immediate administration of Epinephrine (Epi) is critical to save lives in these situations. The current protocol for systemic reactions in immunotherapy is for the prescribing physician to reassess the dosing and schedule as well as the risk:benefit assessment for the therapy and determine whether or not to proceed. PATIENT CONCERNS: The patient revealed concerns regarding the neurologic sequela sustained after undergoinig life-threatening anaphylactic shock...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29686538/hymenoptera-sting-reactions-in-southern-italy-forestry-workers-our-experience-compared-to-reported-data
#7
Luisa Ricciardi, Francesco Papia, Giuseppe Cataldo, Mario Giorgianni, Giovanna Spatari, Sebastiano Gangemi
Background: Hymenoptera sting reactions are among life-threatening causes of allergy. Several epidemiology studies have assessed the risk of these kind of reactions, among the general population, around 3% of adults. This incidence increases among highly at risk populations such as outdoor workers. Hymenoptera stings among forestry workers (FW) are occupational triggers but it has not yet been well defined which is the real incidence of anaphylaxis in these workers, not even in Italy...
2018: Clinical and Molecular Allergy: CMA
https://www.readbyqxmd.com/read/29684568/current-trends-in-food-allergy-induced-anaphylaxis-management-at-school
#8
REVIEW
Matthew Greenhawt, Dana Wallace, Wesley Sublet, Erin Maughan, Andrea Tanner, Kevin Kelly, Stanley Fineman, Martha White, Gene Cash, Charmayne Anderson, Sally Schoessler, Ruchi Gupta, Michael Pistiner
OBJECTIVE: To review the evidence and current policies regarding the use of epinephrine at schools and child care centers Data Sources and Study Selection: A narrative review was performed based on the result of conference proceedings of a group of inter-professional stakeholders who attended the USAnaphylaxis Summit 2017 presented by Allergy & Asthma Network. RESULTS: Anaphylaxis is a well-recognized medical emergency requiring prompt treatment with intramuscular epinephrine...
April 20, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29656144/short-and-long-term-management-of-cases-of-venom-induced-anaphylaxis-via-is-suboptimal
#9
Ashley Tritt, Sofianne Gabrielli, Sarah Zahabi, Ann Clarke, Jocelyn Moisan, Harley Eisman, Judy Morris, Lea Restivo, Greg Shand, Moshe Ben-Shoshan
BACKGROUND: Venom induced anaphylaxis (VIA) accounts for severe reactions. However, little is known about the short and long-term management of VIA cases. OBJECTIVE: To assess the short and long-term management of VIA. METHODS: Using a national anaphylaxis registry (C-CARE), we identified VIA cases presenting to EDs in Montreal and to emergency medical services(EMS) in Western Quebec over a four-year period. Data were collected on clinical characteristics, triggers, and management...
April 12, 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29621018/management-of-anaphylaxis-in-spain-pediatric-emergency-care-providers-knowledge
#10
Mikel Olabarri, Sebastiá Gonzalez-Peris, Paula Vázquez, Aranzazu González-Posada, Nuria Sanz, Ana Vinuesa, Nuria Diez, Javier Benito, Santiago Mintegi
BACKGROUND: Acute care providers must diagnose and treat patients with anaphylaxis. The objective was to analyze Spanish pediatric emergency departments' (ED) providers' knowledge of the international recommendations for the management of anaphylaxis. METHODS: A web-based survey including providers (both attending and residents) from seven Spanish pediatric EDs was conducted. To analyze the knowledge of the identification of anaphylaxis, we used the diagnostic criteria given by the National Institute of Allergy and Infectious Disease and Food Allergy and the Food Allergy and Anaphylaxis Network (2005)...
April 4, 2018: European Journal of Emergency Medicine: Official Journal of the European Society for Emergency Medicine
https://www.readbyqxmd.com/read/29615480/improving-anaphylaxis-care-the-impact-of-a-clinical-pathway
#11
Juhee Lee, Bonnie Rodio, Jane Lavelle, Megan Ott Lewis, Rachel English, Sarah Hadley, Jennifer Molnar, Cynthia Jacobstein, Antonella Cianferoni, Jonathan Spergel, Lisa Zielinski, Nicholas Tsarouhas, Terri Brown-Whitehorn
BACKGROUND: Recommended durations of observation after anaphylaxis have been widely variable, with many ranging from 4 to 24 hours. Prolonged durations often prompt admission for ongoing observation. METHODS: In a multidisciplinary quality improvement initiative, we revised our emergency department (ED) anaphylaxis clinical pathway. Our primary aim was to safely decrease the recommended length of observation from 8 to 4 hours and thereby decrease unnecessary hospitalizations...
May 2018: Pediatrics
https://www.readbyqxmd.com/read/29609214/barriers-to-the-administration-of-epinephrine-in-schools
#12
Susan L Hogue, Rafael Muniz, Christopher Herrem, Suyapa Silvia, Martha V White
BACKGROUND: Anaphylaxis is a serious and growing concern in the school setting as the prevalence of food allergies and food-induced severe allergic reactions continues to increase. METHODS: A cross-sectional, web-based survey was conducted regarding anaphylactic events that occurred during the 2014-2015 school year. Eligible schools were enrolled in the EPIPEN4SCHOOLS® program (Mylan Specialty L.P., Canonsburg, PA), which provides free epinephrine auto-injectors to qualifying US schools...
May 2018: Journal of School Health
https://www.readbyqxmd.com/read/29606638/epinephrine-in-severe-allergic-reactions-the-european-anaphylaxis-register
#13
Linus B Grabenhenrich, Sabine Dölle, Franziska Ruëff, Jean-Marie Renaudin, Kathrin Scherer, Claudia Pföhler, Regina Treudler, Alice Koehli, Vera Mahler, Thomas Spindler, Lars Lange, Maria Beatrice Bilò, Nikolaos G Papadopoulos, Jonathan O B Hourihane, Roland Lang, Montserrat Fernández-Rivas, George Christoff, Ewa Cichocka-Jarosz, Margitta Worm
BACKGROUND: Current guidelines recommend intramuscular administration of epinephrine as the first-line drug for the emergency treatment of severe allergic reactions (anaphylaxis), but no randomized trial evidence supports this consensus. OBJECTIVE: We aimed to assess anaphylaxis treatment practices over 10 years, covering several European regions, all allergen sources, and all age groups. METHODS: The European Anaphylaxis Register tracks elicitors, symptoms, emergency treatment, diagnostic workups, and long-term counseling for anaphylaxis incidents through web-based data entry from tertiary allergy specialists, covering information from the emergency respondent, patient, tertiary referral, and laboratory/clinical test results...
March 29, 2018: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29601357/application-of-precision-medicine-to-the-treatment-of-anaphylaxis
#14
Marina Labella, Marlene Garcia-Neuer, Mariana Castells
PURPOSE OF REVIEW: Recognize the presentation of anaphylaxis for prompt management and treatment and to provide tools for the diagnosis of the underlying cause(s) and set up a long-term treatment to prevent recurrence of anaphylaxis. RECENT FINDINGS: The recent description of phenotypes provides new insight and understanding into the mechanisms and causes of anaphylaxis through a better understanding of endotypes and biomarkers for broad clinical use. SUMMARY: Anaphylaxis is the most severe hypersensitivity reaction and can lead to death...
June 2018: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29561357/how-to-manage-food-allergy-in-nursery-or-school
#15
Roxanne C Oriel, Julie Wang
PURPOSE OF REVIEW: The aim of this review is to describe effective management strategies in nursery or school based upon research findings. RECENT FINDINGS: The prevalence of food allergy and number of emergency department visits for food-related anaphylaxis are increasing in children and adolescents. As there is currently no cure, the most effective strategy to decrease allergic reactions is food allergen avoidance. However, allergic reactions are inevitable in both food allergic children as well as in first-time reactors...
June 2018: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29542298/immediate-hypersensitivity-reactions-induced-by-triamcinolone-in-a-patient-with-atopic-dermatitis
#16
Jee Hee Son, Sook Young Park, Yong Se Cho, Bo Young Chung, Hye One Kim, Chun Wook Park
Corticosteroids are potent anti-inflammatory and anti-allergic agents used in the treatment of various inflammatory diseases, including allergic disease. They are frequently considered the therapy-of-choice for many skin diseases. However, allergic reactions caused by corticosteroids have been reported. Among these, delayed reactions to topical steroids are more common, whereas immediate reactions to systemic steroids are rare. Herein, we report the case of a 32-year-old woman with triamcinolone-induced immediate hypersensitivity reaction, in which the patient had a positive prick test result with triamcinolone...
March 19, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29508717/school-nurse-perspectives-on-school-policies-for-food-allergy-and-anaphylaxis
#17
Lauren M Kao, Julie Wang, Olga Kagan, Anne Russell, S Shahzad Mustafa, Diane Houdek, Bridget Smith, Ruchi Gupta
BACKGROUND: Although school health care professionals are integral to the management of students with food allergy, their views on school food allergy policies have not yet been reported. OBJECTIVE: To characterize food allergy policies currently being used in schools and their utility and potential barriers to implementation from the perspective of school health care professionals. METHODS: An electronic survey was disseminated to school nurses at the 2016 National Association of School Nurses meeting and through the Allergy and Asthma Network listserv...
March 2018: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/29505006/clinically-suspected-anaphylaxis-induced-by-sugammadex-in-a-patient-with-weaver-syndrome-undergoing-restrictive-mammoplasty-surgery-a-case-report-with-the-literature-review
#18
REVIEW
Nurdan Bedirli, Berrin Işık, Mehrnoosh Bashiri, Kutluk Pampal, Ömer Kurtipek
RATIONALE: Sugammadex is a cylodextrin derivate that encapsulates steroidal neuromuscular blocker agents and is reported as a safe and well-tolerated drug. In this case report, we present a patient who developed grade 3 anaphylaxis just after sugammadex administration. PATIENT CONCERNS: A 22-year-old woman with diagnosis of Weaver syndrome was scheduled for bilateral mammoplasty and resection of unilateral accessory breast tissue resection. Anesthesia was induced and maintained by propofol, rocuronium, and remifentanil...
January 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29501378/is-surgical-antibiotic-prophylaxis-necessary-for-pediatric-orchiopexy
#19
A J Rensing, B M Whittam, K H Chan, M P Cain, A E Carroll, W E Bennett
INTRODUCTION: Surgeons frequently use surgical antibiotic prophylaxis (SAP), despite limited evidence to support its efficacy. Potential adverse events associated with antibiotic use include allergic reaction (including anaphylaxis), Clostridium difficile infection, and selecting for resistant bacteria. Surgical site infections (SSI) are very rare in patients undergoing clean pediatric urologic procedures. Current guidelines are unclear about the efficacy of surgical antibiotic prophylaxis for prevention of SSI in the pediatric population...
February 21, 2018: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29477569/a-multicenter-evaluation-of-diagnosis-and-management-of-omega-5-gliadin-allergy-also-known-as-wheat-dependent-exercise-induced-anaphylaxis-in-132-adults
#20
Lucinda Kennard, Iason Thomas, Krzysztof Rutkowski, Vian Azzu, Patrick F K Yong, Bogusia Kasternow, Hannah Hunter, Naeema M O Cabdi, Alla Nakonechna, Annette Wagner
BACKGROUND: Omega-5 gliadin allergy (also known as wheat-dependent exercise-induced anaphylaxis) is a rare allergy to wheat that often presents with intermittent severe anaphylaxis in the context of a cofactor, such as exercise. OBJECTIVE: To undertake a detailed clinical characterization of the largest cohort of patients with omega-5 gliadin allergy to date. METHODS: We retrospectively analyzed the demographic characteristics, presentation, investigation, and management of 132 patients presenting with omega-5 gliadin allergy in 4 UK centers...
March 1, 2018: Journal of Allergy and Clinical Immunology in Practice
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