Read by QxMD icon Read

Alcohol pregnancy

Flavia Westphal, Suzete Maria Fustinoni, Vânia Lopes Pinto, Patrícia de Souza Melo, Anelise Riedel Abrahão
Objective: To identify the profile of women seen in a Fetal Medicine unit, diagnosed with fetal abnormality incompatible with neonatal survival in their current pregnancy, and to check the association of gestational age upon diagnosis with the option of pregnancy termination. Methods: This is a retrospective cohort study carried out in the Fetal Medicine Outpatients Clinic of a university hospital, in the city of São Paulo (SP), Brazil, using medical records of pregnant women with fetus presenting abnormalities incompatible with neonatal survival...
July 2016: Einstein
Nancy Baugh, David E Harris, AbouEl-Makarim Aboueissa, Cheryl Sarton, Erika Lichter
The objective of this study is to understand the relationships between prepregnancy obesity and excessive gestational weight gain (GWG) and adverse maternal and fetal outcomes. Pregnancy risk assessment monitoring system (PRAMS) data from Maine for 2000-2010 were used to determine associations between demographic, socioeconomic, and health behavioral variables and maternal and infant outcomes. Multivariate logistic regression analysis was performed on the independent variables of age, race, smoking, previous live births, marital status, education, BMI, income, rurality, alcohol use, and GWG...
2016: Journal of Pregnancy
Amanda Bye, Jill Shawe, Judith Stephenson, Debra Bick, Nataliya Brima, Nadia Micali
OBJECTIVE: Being underweight at pregnancy commencement is associated with a range of adverse maternal and infant outcomes, as is being overweight or obese, yet it is an aspect of maternal health which has been relatively neglected by healthcare professionals and researchers. We aimed to investigate differences in pre-pregnancy and pregnancy healthy lifestyle advice routinely offered by relevant healthcare professionals, including midwives and GPs, to women across three different BMI categories - underweight, normal, and overweight or obese...
September 23, 2016: Midwifery
Steve Gregory, Yasmin Iles-Caven, Joseph R Hibbeln, Caroline M Taylor, Jean Golding
OBJECTIVES: There have been conflicting data suggesting that prenatal mercury exposure is associated with adverse cardiovascular measures in children. We therefore analysed a large prospective population study to investigate whether prenatal mercury exposure might influence offspring blood pressure (BP) and heart rate adversely. DESIGN: Prospective birth cohort. SETTING: The Avon Longitudinal Study of Parents and Children (ALSPAC). PARTICIPANTS: Maternal whole blood collected in the first half of pregnancy was assayed for mercury and selenium...
October 14, 2016: BMJ Open
Ryan Mills, Steve Kisely, Rosa Alati, Lane Strathearn, Jake M Najman
AIMS: To investigate whether: (1) child maltreatment is associated with lifetime cannabis use, early onset cannabis use, daily cannabis use and DSM-IV cannabis abuse in young adulthood; and (2) behaviour problems, tobacco use and alcohol use at 14 are associated with cannabis use. DESIGN: Birth cohort using linked government agency child protection data to define exposure to child maltreatment. SETTING: The Mater-University of Queensland Study of Pregnancy in Brisbane, Australia...
October 14, 2016: Addiction
Philip A May, Anna-Susan Marais, Marlene M de Vries, Wendy O Kalberg, David Buckley, Julie M Hasken, Colleen M Adnams, Ronel Barnard, Belinda Joubert, Marise Cloete, Barbara Tabachnick, Luther K Robinson, Melanie A Manning, Kenneth Lyons Jones, Heidre Bezuidenhout, Soraya Seedat, Charles D H Parry, H Eugene Hoyme
BACKGROUND: The prevalence and characteristics of the continuum of diagnoses within fetal alcohol spectrum disorders (FASD) were researched in a fifth sample in a South African community. METHODS: An active case ascertainment approach was employed among all first grade learners in this community (n=862). Following individual examination by clinical geneticists/dysmorphologists, cognitive/behavioral testing, and maternal interviews, final diagnoses were made in multidisciplinary case conferences...
October 6, 2016: Drug and Alcohol Dependence
Saba W Masho, Susan Cha, Derek A Chapman, David Chelmow
BACKGROUND: Preterm birth is one of the leading causes of infant morbidity and mortality. Although major strides have been made in identifying risk factors for preterm birth, the complexities between social and individual risk factors are not well understood. OBJECTIVE: This study examines the association between neighborhood youth violence and preterm birth. STUDY DESIGN: A ten-year live birth registry dataset (2004-2013) from Richmond, Virginia, a mid-sized, racially diverse city was analyzed (N=27,519)...
October 8, 2016: American Journal of Obstetrics and Gynecology
Miguel Del Campo, Kenneth Lyons Jones
The fetal alcohol spectrum of disorders (FASD) includes four diagnostic categories for the clinical consequences of prenatal alcohol exposure (PAE) in the unborn child. Physical features are necessary for the diagnosis of the fetal alcohol syndrome (FAS) and partial pFAS. Moreover, these features are specific and a diagnosis of FAS can be made even in the absence of knowledge of PAE. Not only growth deficits, microcephaly and the 3 facial features (short palpebral fissures, smooth philtrum and narrow vermillion of the upper lip) are characteristic, since other dysmorphic features particularly in the hands are key to the recognition of FAS...
October 8, 2016: European Journal of Medical Genetics
Janis Baird, Mary Barker, Nicholas C Harvey, Wendy Lawrence, Christina Vogel, Megan Jarman, Rufia Begum, Tannaze Tinati, Pamela Mahon, Sofia Strommer, Taylor Rose, Hazel Inskip, Cyrus Cooper
BACKGROUND: The nutritional status and health of mothers influence the growth and development of infants during pregnancy and postnatal life. Interventions that focus on improving the nutritional status and lifestyle of mothers have the potential to optimise the development of the fetus as well as improve the health of mothers themselves. Improving the diets of women of childbearing age is likely to require complex interventions that are delivered in a socially and culturally appropriate context...
October 12, 2016: Trials
Alexis K Matusiewicz, Mark A Ilgen, Kipling M Bohnert
BACKGROUND: Little is known about the impact of motherhood on alcohol use beyond the acute reductions observed in pregnancy. This study characterizes changes in alcohol use for women who did and did not become mothers over three years. METHODS: Data are from the National Epidemiologic Survey of Alcohol and Related Conditions (NESARC). Participants were female respondents aged 18-44 years who did not have children and were not pregnant at wave 1, and who reported having at least one drink in the year prior to wave 1 (n=2118)...
September 5, 2016: Drug and Alcohol Dependence
J I Kalisch-Smith, J E Outhwaite, D G Simmons, M Pantaleon, K M Moritz
Maternal alcohol consumption is common prior to pregnancy recognition and in the rat results in altered placental development and fetal growth restriction. To assess the effect of ethanol (EtOH) exposure on the differentiation of trophoblast stem (TS) cells, mouse TS lines were differentiated in vitro for 6 days in 0%, 0.2% or 1% EtOH. This reduced both trophoblast survival and expression of labyrinth and junctional zone trophoblast subtype-specific genes. This suggests that fetal growth restriction and altered placental development associated with maternal alcohol consumption in the periconceptional period could be mediated in part by direct effects on trophoblast development...
October 2016: Placenta
Christian W Wallwiener, Lisa-Maria Wallwiener, Harald Seeger, Birgitt Schönfisch, Alfred O Mueck, Johannes Bitzer, Stephan Zipfel, Sara Y Brucker, Stephanie Wallwiener, Florin-Andrei Taran, Markus Wallwiener
BACKGROUND: We undertook to study possible determinants of female sexual dysfunction (FSD) in a large cohort of female medical students from German-speaking countries. METHODS: We conducted an online questionnaire-based anonymous survey in a cohort of >2600 female medical students enrolled at German-speaking universities. The questionnaire comprised the Female Sexual Function Index (FSFI) plus additional questions regarding contraception, sexual activity, age, height, weight, lifestyle, activity at work, sexuality and emotional interaction with a steady partner, pregnancy history and plans, health problems, and self-acceptance...
September 30, 2016: Journal of Women's Health
Annika C Montag, Andrew D Hull, Lyubov Yevtushok, Natalya Zymak-Zakutnya, Zoryana Sosyniuk, Viktor Dolhov, Kenneth Lyons Jones, Wladimir Wertelecki, Christina D Chambers
BACKGROUND: Early detection of fetal alcohol spectrum disorders (FASDs) is desirable to allow earlier and more comprehensive interventions to be initiated for the mother and infant. We examined prenatal ultrasound as an early method of detecting markers of the physical features and neurobehavioral deficits characteristic of FASD. METHODS: A longitudinal cohort of pregnant women in Ukraine was recruited as part of the Collaborative Initiative on Fetal Alcohol Spectrum Disorders...
September 30, 2016: Alcoholism, Clinical and Experimental Research
Jane B Ford, Kathrin Schemann, Jillian A Patterson, Jonathan Morris, Robert D Herbert, Christine L Roberts
BACKGROUND: Risk factors for preeclampsia are well established, whereas, the triggers associated with timing of preeclampsia onset are not. The aim of this study was to establish whether recent infection or other triggers were associated with timing of preeclampsia onset. METHODS: We used a case-crossover design with preeclampsia cases serving as their own controls. Women with singleton pregnancies of ≥20 weeks gestation presenting at three hospitals were eligible for inclusion...
September 26, 2016: Paediatric and Perinatal Epidemiology
Isabel C S Carvalho, Carolina da S M Martinelli, Noala V M Milhan, Adriana M P da S Marchini, Tamires P Dutra, Daniela M de Souza, Rosilene F da Rocha
Previous studies suggest that prenatal alcohol exposure affects fetal bone development, including bone quality. This study evaluated the chemical composition of mandibles from newborn rats after maternal 20% alcohol consumption before and throughout gestation. Nine rats were initially distributed into three groups: an Alcohol group, Pair-fed group, and Control group. The groups were fed prespecified diets for 8 weeks before and the 3 weeks during pregnancy. At age 5 days, eight newborns from each group were euthanized (total, n = 24)...
2016: Journal of Oral Science
Julie A Kable, Claire D Coles, Kenneth L Jones, Lyubov Yevtushok, Yaroslav Kulikovsky, Wladimir Wertelecki, Christina D Chambers
BACKGROUND: Prenatal alcohol exposure (PAE) has been found to impact neurophysiological encoding of environmental events negatively in the first year of life but has not been evaluated in older infants or toddlers. Cardiac orienting responses (ORs) collected during a habituation/dishabituation learning paradigm were obtained from 12- to 18-month-olds to assess the impact of PAE beyond the first year of life. METHODS: Participants included women and their toddlers who differed in PAE histories and enrolled in a randomized clinical trial of multivitamin/mineral usage during pregnancy...
September 21, 2016: Alcoholism, Clinical and Experimental Research
Deepa Singal, Marni Brownell, Ana Hanlon-Dearman, Dan Chateau, Sally Longstaffe, Leslie L Roos
INTRODUCTION: Fetal alcohol spectrum disorder (FASD) is a significant public health concern. To prevent FASD, factors that place women at risk for giving birth to children with FASD must be investigated; however, there are little data in this area. This paper describes the development of the Manitoba mothers and FASD study, a retrospective cohort of mothers whose children were diagnosed with FASD, generated to investigate: (1) risk factors associated with giving birth to children with FASD; (2) maternal physical and health outcomes, as well as the usage of health and social services...
2016: BMJ Open
Onni Niemelä, Solja Niemelä, Annukka Ritvanen, Mika Gissler, Aini Bloigu, Marja Vääräsmäki, Eero Kajantie, Martha M Werler, Heljä-Marja Surcel
BACKGROUND: Alcohol use during pregnancy leads to detrimental effects on fetal development. As self-reports by mothers are known to be unreliable for assessing prenatal alcohol exposure, there is a need for sensitive and specific biomarkers for identifying those at risk for alcohol-affected offspring. METHODS: We measured serum gamma-glutamyl transferase (GGT), carbohydrate-deficient transferrin (CDT), a mathematically formulated combination of GGT and CDT (GGT-CDT), and ethylglucuronide (EtG) concentrations from 1,936 mothers with a positive (n = 480) or negative (n = 1,456) history of alcohol use at the time of pregnancy...
September 21, 2016: Alcoholism, Clinical and Experimental Research
Joy Simpson, Andrew D Smith, Abigail Fraser, Naveed Sattar, Mark Callaway, Robert S Lindsay, Debbie A Lawlor, Scott M Nelson
CONTEXT: Maternal adiposity in pregnancy is associated with offspring adiposity and metabolic dysfunction postnatally, including greater risk of non-alcoholic fatty liver disease (NAFLD). Recent genetic analyses suggest a causal effect of greater maternal body mass index on offspring birthweight and ponderal index but the relative roles of the environment in-utero or later in life remains unclear. OBJECTIVE: We sought to determine whether markers of infant adiposity (birthweight, umbilical cord blood leptin, adiponectin and lipids) were associated with markers of NAFLD in adolescence...
September 20, 2016: Journal of Clinical Endocrinology and Metabolism
Suzanne Oparil
Heart disease, stroke, and kidney failure are leading causes of death worldwide, and hypertension is a significant risk factor for each. Hypertension is less common in women, compared to men, in those younger than 45 years of age. This trend is reversed in those 65 years and older. In the US between 2011-2014, the prevalence of hypertension in women and men by age group was 6% vs 8% (18-39 years), 30% vs 35% (40-59 years), and 67% vs 63% (60 years and over). Awareness, treatment, and control rates differ between genders with women being more aware of their diagnosis (85% vs 80%), more likely to take their medications (81% vs 71%) and more frequently having controlled hypertension (55% vs 49%)...
September 2016: Journal of Hypertension
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"