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https://www.readbyqxmd.com/read/29166482/abortion-and-sex-related-conditions-in-substance-dependent-brazilian-patients
#1
Alessandra Diehl, Sandra Cristina Pillon, Manoel Antonio Dos Santos, Ronaldo Laranjeira
Abortion is a very sensitive issue with relevance to public health; however few clinical or population-based studies have examined induced abortion among drug users. The study aims to evaluate the prevalence of induced abortion and sex-related conditions in an inpatient drug user sample. A cross-sectional design study was conducted in an inpatient addiction treatment unit in São Paulo, Brazil, with a sample of 616 patients, aged 18-75. Sociodemographic data, sexual behavior, and dependence severity were evaluated in relation to induced abortion...
November 21, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/29164171/health-care-students-attitudes-about-alcohol-consumption-during-pregnancy-responses-to-narrative-vignettes
#2
Kelly D Coons, Shelley L Watson, Nicole M Yantzi, Nancy E Lightfoot, Sylvie Larocque
This article explores medical, midwifery, and nurse practitioner students' attitudes about women who may consume alcohol throughout their pregnancies. Twenty-one health care students responded to a scenario-based vignette addressing alcohol consumption during pregnancy, as well as a semistructured interview, which were analyzed using Braun and Clarke's thematic analysis approach. Two primary themes related to students' attitudes concerning alcohol consumption during pregnancy were identified: (a) divergent recommendations for different women, based on perceptions of their level of education, culture/ethnicity, and ability to stop drinking; and (b) understanding the social determinants of health, including the normalization of women's alcohol consumption and potential partner violence...
January 2017: Global Qualitative Nursing Research
https://www.readbyqxmd.com/read/29162685/tobacco-alcohol-and-illicit-drugs-during-pregnancy-and-risk-of-neuroblastoma-systematic-review
#3
Eloise Müller-Schulte, Gerhard Kurlemann, Anja Harder
OBJECTIVE: To determine whether prenatal and perinatal maternal consumption of alcohol, tobacco and/or illicit drugs is associated with risk of neuroblastoma. DATA SOURCES: Medline and Embase (both from inception to February 2017), and reference lists of included studies. STUDY SELECTION: To be eligible, a study had to be an original report including data on intake of alcohol, tobacco smoking and/or consumption of illicit drugs during pregnancy and risk of neuroblastoma in the child...
November 21, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/29146504/minocycline-protects-developing-brain-against-ethanol-induced-damage
#4
Xin Wang, Kai Zhang, Fanmuyi Yang, Zhenhua Ren, Mei Xu, Jacqueline A Frank, Zun-Ji Ke, Jia Luo
Fetal alcohol spectrum disorders (FASD) are caused by ethanol exposure during the pregnancy and is the leading cause of mental retardation. Ethanol exposure during the development results in the loss of neurons in the developing brain, which may underlie many neurobehavioral deficits associated with FASD. It is important to understand the mechanisms underlying ethanol-induced neuronal loss and develop appropriate therapeutic strategies. One of the potential mechanisms involves neuroimmune activation. Using a third trimester equivalent mouse model of ethanol exposure, we demonstrated that ethanol induced a wide-spread neuroapoptosis, microglial activation, and neuroinflammation in C57BL/6 mice...
November 14, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/29141591/the-impact-of-pregnancy-loss-on-men-s-health-and-wellbeing-a-systematic-review
#5
Clemence Due, Stephanie Chiarolli, Damien W Riggs
BACKGROUND: Research indicates that men's psychological and physical health outcomes after pregnancy loss differ from those of women. Our goal was to identify all literature with a focus on men's experiences of pregnancy loss in order to outline current evidence concerning men's wellbeing. METHODS: A systematic review of literature on men and pregnancy loss was undertaken following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA), Joanna Briggs Institute (JBI) and Social Care Institute for Excellence (SCIE) guidelines...
November 15, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29136159/associations-between-maternal-lifestyle-factors-and-neonatal-body-composition-in-the-screening-for-pregnancy-endpoints-cork-cohort-study
#6
Darren L Dahly, Xia Li, Hazel A Smith, Ali S Khashan, Deirdre M Murray, Mairead E Kiely, Jonathan O'B Hourihane, Fergus P McCarthy, Louise C Kenny, Patricia M Kearney
Background: Neonatal body composition likely mediates fetal influences on life long chronic disease risk. A better understanding of how maternal lifestyle is related to newborn body composition could thus inform intervention efforts. Methods: Using Cork participant data (n = 1754) from the Screening for Pregnancy Endpoints (SCOPE) cohort study [ECM5(10)05/02/08], we estimated how pre-pregnancy body size, gestational weight gain, exercise, alcohol, smoking and diet were related to neonatal fat and fat-free mass, as well as length and gestational age at birth, using quantile regression...
November 10, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29135087/screening-women-for-at-risk-alcohol-use-an-introduction-to-screening-brief-intervention-and-referral-to-treatment-sbirt-in-women-s-health
#7
Maridee D Shogren, Christine Harsell, Thomasine Heitkamp
A significant number of women engage in at-risk drinking behavior, or heavy alcohol use. Women are especially at risk for the negative impact of excessive alcohol consumption secondary to gender differences in body structure, chemistry, and alcohol absorption. In addition, women who drink alcohol during pregnancy risk fetotoxic effects. Screening for at-risk alcohol use is considered best practice during primary care and prenatal care visits and is an integral component of preventive care services for women...
November 14, 2017: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/29120314/ethical-challenges-in-fasd-prevention-scientific-uncertainty-stigma-and-respect-for-women-s-autonomy
#8
Natalie Zizzo, Eric Racine
Fetal alcohol spectrum disorder (FASD) is a leading form of neurodevelopmental delay in Canada, affecting an estimated 3000 babies per year. FASD involves a range of disabilities that entail significant costs to affected individuals, families, and society. Exposure to alcohol in utero is a necessary factor for FASD development, and this has led to FASD being described as "completely preventable". However, there are significant ethical challenges associated with FASD prevention. These challenges revolve around 1) what should be communicated about the risks of alcohol consumption during pregnancy, given some ongoing scientific uncertainty about the effects of prenatal alcohol exposure, and 2) how to communicate these risks, given the potential for stigma against women who give birth to children with FASD as well as against children and adults with FASD...
November 9, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/29120249/alcohol-addiction-the-safety-of-available-approved-treatment-options
#9
Mariangela Antonelli, Anna Ferrulli, Luisa Sestito, Gabriele A Vassallo, Claudia Tarli, Carolina Mosoni, Maria M Rando, Antonio Mirijello, Antonio Gasbarrini, Giovanni Addolorato
Alcohol Use Disorder (AUD) is a leading cause of mortality and morbidity worldwide. At present disulfiram, naltrexone and acamprosate are approved for the treatment of AUD in U.S. and Europe. Nalmefene is approved in Europe and sodium oxybate is approved in Italy and Austria only. Baclofen received a "temporary recommendation for use" in France. Areas covered. The safety of the medications mentioned above on liver, digestive system, kidney function, nervous system, pregnancy and lactation and their possible side effects are described and discussed...
November 9, 2017: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/29112458/review-detrimental-effects-of-alcohol-exposure-around-conception-putative-mechanisms
#10
Jacinta I Kalisch-Smith, Karen M Moritz
In western countries, alcohol consumption is widespread in women of reproductive age, and in binge quantities. These countries also continue to have high incidences of unplanned pregnancies, with women often reported to cease drinking after discovering their pregnancy. This suggests the early embryo may be highly exposed to the detrimental effects of alcohol during this periconceptional period. The periconception and pre-implantation windows which includes maturation of the oocyte, fertilisation and morphogenesis of the pre-implantation embryo, are particularly sensitive times of development...
November 7, 2017: Biochemistry and Cell Biology, Biochimie et Biologie Cellulaire
https://www.readbyqxmd.com/read/29111920/unwanted-pregnancy-pregnancy-loss-and-other-risk-factors-for-intimate-partner-violence-in-the-democratic-republic-of-the-congo
#11
Fentanesh Nibret Tiruneh, Kun-Yang Chuang, Peter A M Ntenda, Ying-Chih Chuang
The Democratic Republic of the Congo (DRC) has one of the highest rates of violence against women in the world; however, few studies have focused on this issue. In this study, we assessed the interrelationship among intimate partner violence (IPV), unintended pregnancy, pregnancy loss, and other sociodemographic factors in the DRC. Our analyses were based on data from the DRC Demographic and Health Survey, conducted from November 2013 to February 2014. We constructed generalized estimating equation models to analyze the data from a sample of 5,120 married women...
November 7, 2017: Women & Health
https://www.readbyqxmd.com/read/29107713/the-enduring-impact-of-neurulation-stage-alcohol-exposure-a-combined-behavioral-and-structural-neuroimaging-study-in-adult-male-and-female-c57bl-6j-mice
#12
E W Fish, L A Wieczorek, A Rumple, M Suttie, S S Moy, P Hammond, S E Parnell
Prenatal alcohol exposure (PAE) can cause behavioral and brain alterations over the lifespan. In animal models, these effects can occur following PAE confined to critical developmental periods, equivalent to the third and fourth weeks of human gestation, before pregnancy is usually recognized. The current study focuses on PAE during early neurulation and examines the behavioral and brain structural consequences that appear in adulthood. On gestational day 8 C57BL/6J dams received two alcohol (2.8g/kg, i.p), or vehicle, administrations, four hours apart...
October 28, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/29097857/like-the-eye-of-the-tiger-inpatient-psychiatric-facility-exclusionary-criteria-and-its-knockout-of-the-emergency-psychiatric-patient
#13
Veronica Tucci, John Liu, Anu Matorin, Asim Shah, Nidal Moukaddam
Context: Over 6% of all emergency department (ED) visits in the United States involve primary mental health or behavioral issues. The patients are stabilized in the ED but frequently require admission to an inpatient psychiatric unit or institution for longer term treatment and management. To facilitate this process, an emergency physician (EP) must first "medically clear" the patient as stable for transfer. At present, there is no interdisciplinary consensus regarding the necessary elements of the medical clearance or stability assessment process...
October 2017: Journal of Emergencies, Trauma, and Shock
https://www.readbyqxmd.com/read/29096279/preconception-lifestyle-changes-in-women-with-planned-pregnancies
#14
Joline Goossens, Dimitri Beeckman, Ann Van Hecke, Ilse Delbaere, Sofie Verhaeghe
OBJECTIVES: (1) to study preconception lifestyle changes and associated factors in women with planned pregnancies; (2) to assess the prevalence of risk factors for adverse pregnancy outcomes in women not reporting any preconception lifestyle changes; and (3) to explore the need for and use of preconception-related advice. DESIGN: secondary data analysis of a cross-sectional study about pregnancy planning. SETTING: six Flemish Hospitals (Belgium)...
October 24, 2017: Midwifery
https://www.readbyqxmd.com/read/29094891/fetal-alcohol-syndrome-and-fetal-alcohol-spectrum-disorders
#15
LeeAnne Denny, Sarah Coles, Robin Blitz
Fetal alcohol syndrome (FAS) and fetal alcohol spectrum disorders (FASD) result from intrauterine exposure to alcohol and are the most common nonheritable causes of intellectual disability. The percentage of women who drink or binge drink during pregnancy has increased since 2012. FAS is commonly missed or misdiagnosed, preventing affected children from receiving needed services in a timely fashion. Diagnosis is based on the presence of the following clinical features, all of which must be present: prenatal and/or postnatal growth retardation, facial dysmorphology, central nervous system dysfunction, and neurobehavioral disabilities...
October 15, 2017: American Family Physician
https://www.readbyqxmd.com/read/29094446/pre-pregnancy-liver-enzyme-levels-and-risk-of-preeclampsia-in-a-subsequent-pregnancy-a-population-based-cohort-study
#16
Geum Joon Cho, Ho Yeon Kim, Jong Heon Park, Ki-Hoon Ahn, Soon-Cheol Hong, Min-Jeong Oh, Hai-Joong Kim
BACKGROUND & AIMS: Preeclampsia is a serious multi-systemic disorder leading to maternal and neonatal adverse outcomes. However, little is known about the early markers of this disease. The aim of this study was to investigate the association between pre-pregnancy liver function and the development of preeclampsia. METHODS: We enrolled 192,571 Korean women who had their first delivery between January 1, 2008, and December 31, 2014, and had undergone a national health screening examination through the National Health Insurance Corporation during 1-2 years before delivery...
November 2, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/29089165/a-case-of-intrauterine-lethal-fetal-injury-after-attempted-suicide-of-the-mother
#17
Lucia Tattoli, Giancarlo Di Vella, Biagio Solarino
Traumatic injuries in pregnancy such as abdominal trauma, pelvic fractures and penetrating trauma are major causes of maternal and neonatal morbidity and mortality. The most common causes of trauma during pregnancy are motor vehicle accidents, falls, assaults, gunshots, and burns. Pregnancy itself has been identified as a risk factor for trauma, together with a younger age, drug use, alcohol use, and domestic violence. We report the case of a 46-year-old woman, 34 weeks pregnant, who attempted suicide by jumping from a flyover, immediately after a probably deliberate traffic collision with the guardrail...
October 18, 2017: Forensic Science International
https://www.readbyqxmd.com/read/29079497/alcohol-use-among-inuit-pregnant-women-validity-of-alcohol-ascertainment-measures-over-time
#18
Marilyn Fortin, Gina Muckle, Sandra W Jacobson, Joseph L Jacobson, Richard E Bélanger
BACKGROUND: Frequency and quantity of alcohol consumed by women are two important indicators of the risks associated with drinking during pregnancy. Some studies have compared the validity of maternal alcohol report obtained during and after pregnancy. However, to date none have examined alcohol use in a Native Canadian population, such as the Inuit. Effective measurement methods are necessary to better understand why children from some communities seem at increased risk of alcohol-related neurodevelopmental disorders...
October 24, 2017: Neurotoxicology and Teratology
https://www.readbyqxmd.com/read/29075360/turnover-of-histones-and-histone-variants-in-postnatal-rat-brain-effects-of-alcohol-exposure
#19
Nadia Rachdaoui, Ling Li, Belinda Willard, Takhar Kasumov, Stephen Previs, Dipak Sarkar
BACKGROUND: Alcohol consumption during pregnancy is a significant public health problem and can result in a continuum of adverse outcomes to the fetus known as fetal alcohol spectrum disorders (FASD). Subjects with FASD show significant neurological deficits, ranging from microencephaly, neurobehavioral, and mental health problems to poor social adjustment and stress tolerance. Neurons are particularly sensitive to alcohol exposure. The neurotoxic action of alcohol, i.e., through ROS production, induces DNA damage and neuronal cell death by apoptosis...
2017: Clinical Epigenetics
https://www.readbyqxmd.com/read/29074280/premature-brain-aging-in-humans-exposed-to-maternal-nutrient-restriction-during-early-gestation
#20
Katja Franke, Christian Gaser, Susanne R de Rooij, Matthias Schwab, Tessa J Roseboom
BACKGROUND: Prenatal exposure to undernutrition is widespread in both developing and industrialized countries, causing irreversible damage to the developing brain, resulting in altered brain structure and decreased cognitive function during adulthood. The Dutch famine in 1944/45 was a humanitarian disaster, now enabling studies of the effects of prenatal undernutrition during gestation on brain aging in late adulthood. METHODS: We hypothesized that study participants prenatally exposed to maternal nutrient restriction (MNR) would demonstrate altered brain structure resembling premature brain aging in late adulthood, expecting the effect being stronger in men...
October 23, 2017: NeuroImage
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