Carolina Khosrawipour, Jakub Nicpoń, Zdzisław Kiełbowicz, Przemysław Prządka, Bartłomiej Liszka, Said Al-Jundi, Veria Khosrawipour, Shiri Li, Hien Lau, Joanna Kulas, Agata Diakun, Wojciech Kielan, Mariusz Chabowski, Agata Mikolajczyk-Martinez
Background: For decades, intraperitoneal chemotherapy (IPC) has been delivered into the abdominal cavity as a liquid solution. Recently the concept of foam as a carrier-solution for IPC was suggested. This in-vivo swine study aims to evaluate the safety, intraoperative parameters, limitations and postoperative complications of foam-based intraperitoneal chemotherapy (FBIC). Methods: Three 65-day-old swine received FBIC with doxorubicin in a laparoscopy setting. Intraoperative parameters were monitored throughout the procedure and an extensive postoperative laboratory monitoring was conducted for 7 days...
2023: Frontiers in Pharmacology