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adrenalcortical carcinoma

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https://www.readbyqxmd.com/read/21932594/clinical-characteristics-of-adrenocortical-tumors-in-children
#1
COMPARATIVE STUDY
Qiu-Li Chen, Zhe Su, Yan-Hong Li, Hua-Mei Ma, Hong-Shan Chen, Min-Lian Du
BACKGROUND: Adrenocortical tumors (ACTs) are rare in children. Because of the rarity and various manifestations of ACTs, patients of ACTs are not easily diagnosed. Some patients were misdiagnosed before surgery. OBJECTIVE: Identify the clinical, laboratorial, imaging and histopathological characteristics of adrenocortical tumors in children. Compare adrenalcortical adenoma with carcinoma. METHODS: A retrospective review of 34 identified patients who were younger than 15 years old with histologic confirmation of adrenocortical carcinoma (ACC) or adenomas from 1991 to 2010...
2011: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/19966938/microarray-gene-expression-profiling-using-core-biopsies-of-renal-neoplasia
#2
Craig G Rogers, Jonathon A Ditlev, Min-Han Tan, Jun Sugimura, Chao-Nan Qian, Jeff Cooper, Brian Lane, Michael A Jewett, Richard J Kahnoski, Eric J Kort, Bin T Teh
We investigate the feasibility of using microarray gene expression profiling technology to analyze core biopsies of renal tumors for classification of tumor histology. Core biopsies were obtained ex-vivo from 7 renal tumors-comprised of four histological subtypes-following radical nephrectomy using 18-gauge biopsy needles. RNA was isolated from these samples and, in the case of biopsy samples, amplified by in vitro transcription. Microarray analysis was then used to quantify the mRNA expression patterns in these samples relative to non-diseased renal tissue mRNA...
2009: American Journal of Translational Research
https://www.readbyqxmd.com/read/16188147/-the-expression-and-significance-of-chromogranin-a-and-synaptophysin-in-adrenal-gland-tumors
#3
Chao Feng, Han-zhong Li, Wei-gang Yan, Yu-feng Luo, Jin-ling Cao
OBJECTIVE: To investigate the expression of chromogranin A (CgA) and synaptophysin (Syn) for differential diagnosis of different kinds of adrenal gland tumors. METHODS: The samples of 69 adrenal gland tumors and 4 normal adrenal glands were immunohistochemically analyzed for the expression of chromogranin A and synaptophysin. The statistical analysis of the data was performed using chi-square test. RESULTS: In the normal adrenal gland, CgA and Syn was exclusively detected in the medulla...
August 2005: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/10970942/-failure-of-bone-marrow-autograft-in-metastatic-malignant-adrenalcortical-carcinoma
#4
E Andrès, J E Kurtz, B Lioure, P Quetin, F Maloisel, J L Schlienger, P Dufour
BACKGROUND: Despite different therapeutic modalities (surgery, hormones therapy, chemotherapy), 5-year survival in patients with malignant adrenocortical carcinoma remains only 10% to 20%. Bone marrow grafts may be proposed to intensify treatment. CASE REPORT: In a 29-year-old patient with adrenocortical carcinoma with metastases to the lung and bone, an adjuvant bone marrow graft using peripheral stem cells was unsuccessful. Recurrence was observed at 3 months and overall survival was 2 years...
September 2000: Annales D'endocrinologie
https://www.readbyqxmd.com/read/2300390/sbla-syndrome-revisited
#5
H T Lynch, B Radford, J F Lynch
We have provided an in-depth, longitudinal, clinical/genetic/pathologic investigation of a family consonant with the sarcoma, breast cancer and brain tumors, lung and laryngeal cancer, leukemia, lymphoma, and adrenalcortical carcinoma syndrome. The pattern of cancer expression involves all three germinal layers with transmission through multiple generations. Segregation of these cancers occur in a manner consonant with an autosomal dominant mode of genetic transmission. It is hoped that recognition of the significance of this tumor pattern within families will provide an impetus for cancer surveillance, control, and laboratory research in the quest for clues to biomarkers which correlate with its cancer-prone genotype...
1990: Oncology
https://www.readbyqxmd.com/read/1817838/-incidentally-discovered-adrenal-tumors-apropos-of-20-cases
#6
REVIEW
J C Le Néel, J C Bourseau, B Guiberteau, M Kohen, L Borde
According to Glazer, the term of incidentaloma describes an adrenal tumor discovered incidentally during acomputed tomographyscan and by extension to all masses discovered whatever the imaging process. Twenty patients have been operated during the last 10 years. The discovering circumstances are not specific, except the ecography and CT Scan. Complementary examinations include biological tests aiming at showing a possible hormonal secretion and more specific examinations MIBG scintygraphy and magnetic resonance imaging...
1991: Chirurgie; Mémoires de L'Académie de Chirurgie
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