keyword
MENU ▼
Read by QxMD icon Read
search

Data Analytics

keyword
https://www.readbyqxmd.com/read/29786965/l-and-d-threo-ethylphenidate-concentrations-pharmacokinetics-and-pharmacodynamics-in-horses
#1
Heather K Knych, Dan S McKemie, Kelsey Seminoff, Petra Hartmann, Lynn Hovda, Dionne Benson
Ethylphenidate is a psychostimulant and analogue of the commonly prescribed compound, methylphenidate (Ritalin®). There are a limited number of studies describing the disposition and pharmacologic/toxicological effects of ethylphenidate in any species. The abuse potential in equine athletes along with the limited data available regarding administration in horses necessitates further study. The objectives of the current study were to describe drug concentrations, develop an analytical method that could be used to regulate its use and describe the pharmacodynamic effects of ethylphenidate in horses...
May 22, 2018: Drug Testing and Analysis
https://www.readbyqxmd.com/read/29786662/study-on-the-discrimination-between-citri-reticulatae-pericarpium-varieties-based-on-hs-spme-gc-ms-combined-with-multivariate-statistical-analyses
#2
Yuying Zheng, Xuan Zeng, Wei Peng, Zhong Wu, Weiwei Su
Citri reticulatae pericarpium (CRP), the dried pericarps of Citrus reticulata Blanco and its cultivars, has been widely used in drugs and foods in China for centuries. In this study, an accurate and feasible analytical method based on HS-SPME-GC-MS coupled with multivariate statistical analyses was developed to comprehensively compare volatile compounds of pericarps derived from Citrus reticulata "Chachi" ("Guangchenpi" in Chinese, GCP) and other cultivars of Citrus reticulata Blanco ("Chenpi" in Chinese, CP)...
May 22, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29786587/legal-protection-of-public-health-through-control-over-genetically-modified-food
#3
Nataliya Gutorova, Olena Batyhina, Maryna Trotska
OBJECTIVE: Introduction: Science is constantly being developed which leads to both positive and negative changes in public health and the environment. One of the results of scientific progress is introduction of food based on genetically modified organisms whose effects on human health, to date, remain scantily studied and are ambiguous. The aim: to determine how human health can be influenced by food production based on genetically modified organisms. PATIENTS AND METHODS: Materials and methods: international acts, data of international organizations and conclusions of scientists have been examined and used in the study...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29786581/development-of-informational-communicative-system-created-to-improve-medical-help-for-family-medicine-doctors
#4
Vladyslav A Smiianov, Natalia O Dryha, Olha I Smiianova, Victor K Obodyak, Tatyana O Zudina
OBJECTIVE: Introduction: Today mobile health`s protection service has no concrete meaning. As an research object it was called mHealth and named by Global observatory of electronic health`s protection as "Doctor and social health practice that can be supported by any mobile units (mobile phones or smartphones), units for patient`s health control, personal computers and other units of non-wired communication". An active usage of SMS in programs for patients` cure regimen keeping was quiet predictable...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29786153/vasa-previa-screening-strategies-a-decision-and-cost-effectiveness-analysis
#5
R G Sinkey, A O Odibo
OBJECTIVE: The aim of this study is to perform a decision and cost-effectiveness analysis comparing four screening strategies for the antenatal diagnosis of vasa previa among singleton pregnancies. METHODS: A decision-analytic model was constructed comparing vasa previa screening strategies. Published probabilities and costs were applied to four transvaginal screening scenarios which occurred at the time of mid-trimester ultrasound: no screening, ultrasound-indicated screening, screening pregnancies conceived by in vitro fertilization (IVF), and universal screening...
May 22, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29785857/a-simulation-study-on-two-analytical-techniques-for-alternating-treatments-designs
#6
Rumen Manolov
Alternating treatments designs (ATDs) are single-case experimental designs entailing the rapid alternation of conditions, and the specific sequence of conditions is usually determined at random. The visual analysis of ATD data entails comparing the data paths formed by connecting the measurements from the same condition. Apart from visual analyses, there are at least two quantitative analytical options also comparing data paths. On option is a visual structured criterion (VSC) regarding the number of comparisons for which one conditions has to be superior to the other to consider that the difference is not only due to random fluctuations...
May 1, 2018: Behavior Modification
https://www.readbyqxmd.com/read/29785519/threshold-dynamics-of-a-temperature-dependent-stage-structured-mosquito-population-model-with-nested-delays
#7
Xiunan Wang, Xingfu Zou
Mosquito-borne diseases remain a significant threat to public health and economics. Since mosquitoes are quite sensitive to temperature, global warming may not only worsen the disease transmission case in current endemic areas but also facilitate mosquito population together with pathogens to establish in new regions. Therefore, understanding mosquito population dynamics under the impact of temperature is considerably important for making disease control policies. In this paper, we develop a stage-structured mosquito population model in the environment of a temperature-controlled experiment...
May 21, 2018: Bulletin of Mathematical Biology
https://www.readbyqxmd.com/read/29784607/telestroke-adoption-among-community-hospitals-in-north-carolina-a-cross-sectional-study
#8
Christopher M Shea, Amir Alishahi Tabriz, Kea Turner, Steve North, Kristin L Reiter
OBJECTIVE: This study identifies community and hospital characteristics associated with adoption of telestroke among acute care hospitals in North Carolina (NC). METHODS: Our sample included 107 hospitals located in NC. Our analytic dataset included variables from the American Hospital Association (AHA) annual survey, AHA Health IT supplement, Healthcare Cost Report Information System, and Centers for Disease Control and Prevention's WONDER online database. We supplemented our secondary sources with data on telestroke adoption and market-level variables developed for NC...
May 18, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29784413/a-ricin-forensic-profiling-approach-based-on-a-complex-set-of-biomarkers
#9
Sten-Åke Fredriksson, David S Wunschel, Susanne Wiklund Lindström, Calle Nilsson, Karen Wahl, Crister Åstot
A forensic method for the retrospective determination of preparation methods used for illicit ricin toxin production was developed. The method was based on a complex set of biomarkers, including carbohydrates, fatty acids, seed storage proteins, in combination with data on ricin and Ricinus communis agglutinin. The analyses were performed on samples prepared from four castor bean plant (R. communis) cultivars by four different sample preparation methods (PM1-PM4) ranging from simple disintegration of the castor beans to multi-step preparation methods including different protein precipitation methods...
August 15, 2018: Talanta
https://www.readbyqxmd.com/read/29784408/part-2-forensic-attribution-profiling-of-russian-vx-in-food-using-liquid-chromatography-mass-spectrometry
#10
Daniel Jansson, Susanne Wiklund Lindström, Rikard Norlin, Saphon Hok, Carlos A Valdez, Audrey M Williams, Armando Alcaraz, Calle Nilsson, Crister Åstot
This work is part two of a three-part series in this issue of a Sweden-United States collaborative effort towards the understanding of the chemical attribution signatures of Russian VX (VR) in synthesized samples and complex food matrices. In this study, we describe the sourcing of VR present in food based on chemical analysis of attribution signatures by liquid chromatography-tandem mass spectrometry (LC-MS/MS) combined with multivariate data analysis. Analytical data was acquired from seven different foods spiked with VR batches that were synthesized via six different routes in two separate laboratories...
August 15, 2018: Talanta
https://www.readbyqxmd.com/read/29784391/exploiting-the-synergistic-effect-of-concurrent-data-signals-low-level-fusion-of-liquid-chromatographic-with-dual-detection-data
#11
Carla M Teglia, Silvana M Azcarate, Mirta R Alcaráz, Héctor C Goicoechea, María J Culzoni
A low-level data fusion strategy was developed and implemented for data processing of second-order liquid chromatographic data with dual detection, i.e. absorbance and fluorescence monitoring. The synergistic effect of coupling individual information provided by two different detectors was evaluated by analyzing the results gathered after the application of a series of data preprocessing steps and chemometric resolution. The chemometric modeling involved data analysis by MCR-ALS, PARAFAC and N-PLS. Their ability to handle the new data block was assessed through the estimation of the analytical figures of merits achieved in the prediction of a validation set containing fifteen fluorescent and non-fluorescent veterinary active ingredients that can be found in poultry litter...
August 15, 2018: Talanta
https://www.readbyqxmd.com/read/29784338/ionic-liquids-as-signal-amplifiers-for-the-simultaneous-extraction-of-several-neurotransmitters-determined-by-micellar-electrokinetic-chromatography
#12
Natalia Miękus, Ilona Olędzka, Natalia Kossakowska, Alina Plenis, Piotr Kowalski, Adam Prahl, Tomasz Bączek
Nowadays, ionic liquids (ILs) are receiving more attention in various fields of analytical chemistry. Their contribution to the enhancement of the clean-up, extraction, separation and determination of trace amounts of various biologically important compounds in distinct matrices is well documented. Moreover, their importance as "green chemistry" solvents has been pointed out. Advanced analytical methods based on the IL-assisted microextraction and electrophoretic determination of minute concentrations of neurotransmitters (NTs) in samples are presented here for the first time...
August 15, 2018: Talanta
https://www.readbyqxmd.com/read/29783953/immunologic-and-virological-response-to-art-among-hiv-infected-individuals-at-a-tertiary-hospital-in-ghana
#13
Dorcas Obiri-Yeboah, Faustina Pappoe, Ibrahim Baidoo, Francis Arthur, Anna Hayfron-Benjamin, Samuel Essien-Baidoo, Godwin Kwakye-Nuako, Stephen Ayisi Addo
BACKGROUND: The need to study the outcome of Antiretroviral Therapy (ART) among Human Immunodeficiency Virus (HIV) infected individuals in Ghana, a sub-Saharan African country crucial in the era of the "Treat All" policy. The aim of this study was to analyze selected determinants of immunological and virological response to ART among HIV infected individuals in a tertiary facility in Cape Coast, Ghana. METHODS: An analytical cross sectional study with a retrospective component was conducted in the Cape Coast Teaching Hospital (CCTH), Central Region...
May 21, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29783897/continuous-glucose-monitoring-current-use-in-diabetes-management-and-possible-future-applications
#14
Martina Vettoretti, Giacomo Cappon, Giada Acciaroli, Andrea Facchinetti, Giovanni Sparacino
The recent announcement of the production of new low-cost continuous glucose monitoring (CGM) sensors, the approval of marketed CGM sensors for making treatment decisions, and new reimbursement criteria have the potential to revolutionize CGM use. After briefly summarizing current CGM applications, we discuss how, in our opinion, these changes are expected to extend CGM utilization beyond diabetes patients, for example, to subjects with prediabetes or even healthy individuals. We also elaborate on how the integration of CGM data with other relevant information, for example, health records and other medical device/wearable sensor data, will contribute to creating a digital data ecosystem that will improve our understanding of the etiology and complications of diabetes and will facilitate the development of data analytics for personalized diabetes management and prevention...
May 1, 2018: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29783843/big-groundwater-datasets-reveal-possible-rare-contamination-amid-otherwise-improved-water-quality-for-some-analytes-in-a-region-of-marcellus-shale-development
#15
Tao Wen, Xianzeng Niu, Matthew Gonzales, Guanjie Zheng, Zhenhui Li, Susan Louise Brantley
Eleven thousand groundwater samples collected in the 2010s in an area of Marcellus shale-gas development are analyzed to assess spatial and temporal patterns of water quality. Using a new data mining technique, we confirm previous observations that methane concentrations in groundwater tend to be naturally elevated in valleys and near faults, but we also show that methane is also more concentrated near anticlines. Data mining also highlights waters with elevated methane that are not otherwise explained by geologic features...
May 22, 2018: Environmental Science & Technology
https://www.readbyqxmd.com/read/29783712/a-multimodal-deep-log-based-user-experience-ux-platform-for-ux-evaluation
#16
Jamil Hussain, Wajahat Ali Khan, Taeho Hur, Hafiz Syed Muhammad Bilal, Jaehun Bang, Anees Ul Hassan, Muhammad Afzal, Sungyoung Lee
The user experience (UX) is an emerging field in user research and design, and the development of UX evaluation methods presents a challenge for both researchers and practitioners. Different UX evaluation methods have been developed to extract accurate UX data. Among UX evaluation methods, the mixed-method approach of triangulation has gained importance. It provides more accurate and precise information about the user while interacting with the product. However, this approach requires skilled UX researchers and developers to integrate multiple devices, synchronize them, analyze the data, and ultimately produce an informed decision...
May 18, 2018: Sensors
https://www.readbyqxmd.com/read/29783669/limits-to-the-evaluation-of-the-accuracy-of-continuous-glucose-monitoring-systems-by-clinical-trials
#17
Patrick Schrangl, Florian Reiterer, Lutz Heinemann, Guido Freckmann, Luigi Del Re
Systems for continuous glucose monitoring (CGM) are evolving quickly, and the data obtained are expected to become the basis for clinical decisions for many patients with diabetes in the near future. However, this requires that their analytical accuracy is sufficient. This accuracy is usually determined with clinical studies by comparing the data obtained by the given CGM system with blood glucose (BG) point measurements made with a so-called reference method. The latter is assumed to indicate the correct value of the target quantity...
May 18, 2018: Biosensors
https://www.readbyqxmd.com/read/29783186/-1-h-nmr-and-uplc-ms-metabolomics-functional-tools-for-exploring-chemotypic-variation-in-sceletium-tortuosum-from-two-provinces-in-south-africa
#18
Jianping Zhao, Ikhlas A Khan, Sandra Combrinck, Maxleene Sandasi, Weiyang Chen, Alvaro M Viljoen
Sceletium tortuosum (Aizoaceae) is widely recognised for the treatment of stress, anxiety and depression, as well as for obsessive compulsive disorders. A comprehensive intraspecies chemotypic variation study, using samples harvested from two distinct regions of South Africa, was done using both proton nuclear magnetic resonance (1 H-NMR) spectroscopy of methanol extracts (N = 145) and ultra performance liquid chromatography-mass spectrometry (UPLC-MS) of acid/base extracts (N = 289). Chemometric analysis of the 1 H-NMR data indicated two main clusters that were region-specific (Northern Cape and Western Cape provinces)...
May 17, 2018: Phytochemistry
https://www.readbyqxmd.com/read/29783172/headspace-sorptive-extraction-gas-chromatography-mass-spectrometry-method-to-measure-volatile-emissions-from-human-airway-cell-cultures
#19
Mei S Yamaguchi, Mitchell M McCartney, Angela L Linderholm, Susan E Ebeler, Michael Schivo, Cristina E Davis
The human respiratory tract releases volatile metabolites into exhaled breath that can be utilized for noninvasive health diagnostics. To understand the origin of this metabolic process, our group has previously analyzed the headspace above human epithelial cell cultures using solid phase microextraction-gas chromatography-mass spectrometry (SPME-GC-MS). In the present work, we improve our model by employing sorbent-covered magnetic stir bars for headspace sorptive extraction (HSSE). Sorbent-coated stir bar analyte recovery increased by 52 times and captured 97 more compounds than SPME...
May 12, 2018: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29783145/electrochemical-biosensor-system-using-a-cmos-microelectrode-array-provides-high-spatially-and-temporally-resolved-images
#20
William Tedjo, Jasmine E Nejad, Rachel Feeny, Lang Yang, Charles S Henry, Stuart Tobet, Tom Chen
The ability to view biological events in real time has contributed significantly to research in the life sciences. While video capture of real time changes in anatomical relationships is important, it is equally important to visualize real time changes in the chemical communications that drive cell behaviors. This paper describes an electrochemical imaging system capable of capturing changes in chemical gradients in live tissue slices. The system consists of a CMOS microchip with 8192 configurable Pt surface electrodes, on-chip potentiostat, on-chip control logic, and a microfluidic device designed to interface with the CMOS chip to support ex vivo tissue experimentation...
April 10, 2018: Biosensors & Bioelectronics
keyword
keyword
77105
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"