keyword
MENU ▼
Read by QxMD icon Read
search

Infectious bursal disease virus

keyword
https://www.readbyqxmd.com/read/28620682/infectious-bursal-disease-outbreak-investigation-molecular-characterization-and-vaccine-immunogenicity-trial-in-ethiopia
#1
Aregitu Mekuriaw, Molalegne Bitew, Esyas Gelaye, Bedaso Mamo, Gelagay Ayelet
The study was conducted with the objective of isolation and molecular characterization of infectious bursal disease virus (IBDV) circulating in Ethiopia and to assess the immunogenicity of different commercially available live attenuated IBD vaccines and finally to select the appropriate vaccine strain for the existing IBDV. Outbreak samples collected from different poultry farms with IBD infection between 2013 and 2015 were used for the virus isolation and molecular characterization. IBD vaccine immunogenicity test was conducted using four different commercially available live attenuated IBD vaccine strains: namely D78, B2K, LC75, and EXTREM...
June 15, 2017: Tropical Animal Health and Production
https://www.readbyqxmd.com/read/28619162/impact-of-treatments-for-recycled-broiler-litter-on-the-viability-and-infectivity-of-microorganisms
#2
Daiane Voss-Rech, Iara Maria Trevisol, Liana Brentano, Virgínia Santiago Silva, Raquel Rebelatto, Fátima Regina Ferreira Jaenisch, Cintia Hiromi Okino, Marcos Antonio Zanella Mores, Arlei Coldebella, Sônia de Avila Botton, Clarissa Silveira Luiz Vaz
The microbiological risk of recycled litter depends on the efficacy of the management system applied to inactivate residual microorganisms and preserve the health of the successive broiler flock. This study aimed to assess the viability and infectivity of the Newcastle Disease Virus (NDV), Infectious Bursal Disease Virus (IBDV) and Salmonella Heidelberg in recycled litter exposed to different treatments. The litter was contaminated with microorganisms and submitted to the treatments (T): T1: shallow fermentation; T2: quicklime (calcium oxide); T3: shallow fermentation followed by addition of quicklime; T4: no treatment...
May 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28603519/antigen-sparing-and-enhanced-efficacy-of-multivalent-vaccines-adjuvanted-with-immunopotentiators-in-chickens
#3
Peipei Wu, Jihu Lu, Lei Feng, Hongzhuan Wu, Xuehua Zhang, Mei Mei, Jibo Hou, Xiufan Liu, Yinghua Tang
We previously described that immunopotentiators, CVCVA5, increased the efficacy of H5 and H9 subtype avian influenza vaccines in chickens, ducks, and geese. In this study, we further investigated the effects of the CVCVA5 for improving the efficacy of other univalent or multivalent inactivated vaccines. The immune response administrated with half-dose of monovalent vaccine plus CVCVA5 were higher than those of one dose of monovalent vaccine without immunopotentiators as measured by levels of antibodies from serum, tears and bronchoalveolar lavage fluids, and cytokines of IFNγ and IL-4 from serum...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28592532/voltage-dependent-anion-channel-1-interacts-with-ribonucleoprotein-complexes-to-enhance-infectious-bursal-disease-virus-polymerase-activity
#4
Chunyan Han, Xiangwei Zeng, Shuai Yao, Li Gao, Lizhou Zhang, Xiaole Qi, Yulu Duan, Bo Yang, Yulong Gao, Changjun Liu, Yanping Zhang, Yongqiang Wang, Xiaomei Wang
Infectious bursal disease virus (IBDV) is a double-stranded RNA virus. Segment A contains two overlapping open reading frames (ORFs), which encode viral proteins VP2, VP3, VP4, and VP5. Segment B contains one ORF and encodes the viral RNA-dependent RNA polymerase, VP1. IBDV ribonucleoprotein complexes are composed of VP1, VP3, and dsRNA and play a critical role in mediating viral replication and transcription during virus life cycles. Here, we identified a cellular factor, VDAC1, which was upregulated during IBDV infection and found to mediate IBDV polymerase activity...
June 7, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28523925/genetic-and-pathologic-characteristics-of-infectious-bursal-disease-viruses-isolated-from-broiler-chickens-in-iran-during-2014-2015
#5
H Norouzian, G Farjanikish, H Hosseini
Infectious bursal disease (IBD) virus causes a highly contagious immunosuppressive disease in chickens. A total number of 12 pooled bursal samples were collected during 2014-2015 from broiler farms in different regions of Iran. Typical macroscopical and histopathological lesions of the bursa of Fabricius were found similar to reports by other researchers. A 474-bp part of hypervariable region of VP2 (hvVP2) was sequenced and analyzed. Ten isolates had the characteristic amino acid residues of very virulent IBD (vvIBD) viruses and the other two were identified as attenuated (vaccine) strains...
2017: Acta Virologica
https://www.readbyqxmd.com/read/28495316/effect-of-infectious-bursal-disease-ibd-vaccine-on-salmonella-enteritidis-infected-chickens
#6
Nagah Arafat, Abdelfattah H Eladl, Hebatallah Mahgoub, Reham A El-Shafei
BACKGROUND: Chickens infected with both infectious bursal disease virus (IBDV) and Salmonella had higher mortality. In this work, we investigated the effect of IBDV vaccine (modified live-virus bursal disease vaccine, Nobilis strain 228E®) on experimentally infected chickens with Salmonella Enteritidis (SE). METHODS: Four experimental groups were included in this study, negative control group, 228E®group, 228E®+SE infected group, and SE infected group. Chickens were ocularly administrated 228E® at 12days of age and orally infected with S...
June 22, 2017: Vaccine
https://www.readbyqxmd.com/read/28494932/comparison-of-growth-performance-and-immune-parameters-of-three-commercial-chicken-lines-used-in-organic-production
#7
R B Kjærup, H R Juul-Madsen, L R Norup, P Sørensen, T S Dalgaard
Owing to the higher demands for avoiding medication and antibiotics, health status of the production animals plays an important role in the poultry industry, especially in organic poultry systems. Immunity plays a major role in keeping the host free from disease, and it is evident that the host's genetic make-up influences immunity and disease resistance/susceptibility in chickens. Previously, breeding strategies aimed at selection for resistance against specific diseases with the risk of creating less disease resistance against other pathogens...
May 2017: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/28486945/transcription-profiles-of-the-responses-of-chicken-bursae-of-fabricius-to-ibdv-in-different-timing-phases
#8
Changbo Ou, Qiuxia Wang, Yanhong Zhang, Weili Kong, Shouping Zhang, Yan Yu, Jinyou Ma, Xingyou Liu, Xianghui Kong
BACKGROUND: Infectious bursal disease virus (IBDV) infection causes immunosuppression in chickens and increases their susceptibility to secondary infections. To explore the interaction between host and IBDV, RNA-Seq was applied to analyse the transcriptional profiles of the responses of chickens' bursas of Fabricius in the early stage of IBDV infection. RESULTS: The results displayed that a total of 15546 genes were identified in the chicken bursa libraries. Among the annotated genes, there were 2006 and 4668 differentially expressed genes in the infection group compared with the mock group on day 1 and day 3 post inoculation (1 and 3 dpi), respectively...
May 10, 2017: Virology Journal
https://www.readbyqxmd.com/read/28482266/a-recombinant-avian-antibody-against-vp2-of-infectious-bursal-disease-virus-protects-chicken-from-viral-infection
#9
Yingjie Zhang, Jiechao Yin, Tianhe Li, Bing Zhou, Pengfei Xu, Ruixiang Che, Yunye Liu, Hongxue Cao, Xianlong Ye, Yongbi Yang, Xiaole Qi, Shimin Zheng, Guojie Ding, Guiping Ren, Hanchun Yang, Xiaomei Wang, Deshan Li
A stable cell-line was established that expressed the recombinant avian antibody (rAb) against the infectious bursal disease virus (IBDV). rAb exhibited neutralization activity to IBDV-B87 strain in DF1 cells. The minimum rAb concentration required for inhibition of the cytopathic effect (CPE) was 1.563μg/mL. To test the efficacy of rAb, a 168-h cohabitation challenge experiment was performed to transmit the disease from the chickens challenged with vvIBDV (HLJ0504 strain) to three test groups of chickens, i...
April 8, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28447468/induction-of-apoptosis-in-the-bursa-of-fabricius-by-vaccination-against-gumboro-disease
#10
Marcelo Pablo Killian, Juan David Boviez, Mariana Gambarotta, Daniel Marcelo Lombardo
Infectious bursal disease is a severe acute viral disease of young chickens, affecting mainly the B-lymphocytes in the bursa of Fabricius, leading to severe immunosuppression as a result of the death of lymphoid cells. In the bursa infected with infectious bursal disease virus, viral replication is associated with apoptosis of lymphoid cells, inflammatory change and atrophy. Vaccination has appeared to be a crucial factor for control, with live attenuated vaccines being the most used. However, the apoptotic effect of these vaccines on the bursa has not been tested...
June 19, 2017: Avian Pathology: Journal of the W.V.P.A
https://www.readbyqxmd.com/read/28447340/marginal-deficiencies-of-dietary-arginine-and-methionine-could-suppress-growth-performance-and-immunological-responses-in-broiler-chickens
#11
R Jahanian, M Khalifeh-Gholi
The present study was conducted to investigate the effects of different levels of dietary arginine (Arg) and methionine (Met) on performance, immune responses, and carcass characteristics of broiler chickens. A total of 540 day-old Ross 308 broiler chicks were randomly assigned into the nine experimental diets, consisting five replicates of 12 birds each. Dietary treatments included three different levels (90%, 100%, and 110% of National Research Council [NRC] specifications) of either dietary Arg or Met, which were fed to the birds according to a 3 × 3 factorial arrangement of treatments during a 42 days feeding trial...
April 26, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28413051/protective-efficacy-of-a-novel-recombinant-marek-s-disease-virus-vector-vaccine-against-infectious-bursal-disease-in-chickens-with-or-without-maternal-antibodies
#12
Kai Li, Yongzhen Liu, Yanping Zhang, Li Gao, Changjun Liu, Hongyu Cui, Xiaole Qi, Yulong Gao, Li Zhong, Xiaomei Wang
Infectious bursal disease (IBD) causes significant clinical and economic losses to the poultry industry worldwide. Current vaccine programs using live attenuated and inactivated vaccines have numerous drawbacks. As an alternative solution to control IBD, a Marek's disease virus (MDV) vector vaccine (rMDV-VP2) expressing the VP2 gene of infectious bursal disease virus (IBDV) has been developed. In this study, the protective efficacy of rMDV-VP2 was evaluated in a dose-related experiment which showed that a single dose of 1000 PFU was sufficient to fully protect chickens against IBDV infection...
April 2017: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/28402729/differential-regulation-of-chtlr3-by-infectious-bursal-disease-viruses-with-different-virulence-in-vitro-and-in-vivo
#13
Xiumiao He, Yanyan Chen, Synat Kang, Guo Chen, Ping Wei
Toll-like receptor 3 (TLR3) is one of the TLRs whose ligand is double-stranded RNA (dsRNA). Infectious bursal disease virus (IBDV) is a dsRNA virus that could be recognized by TLR3. The purpose of this study was to determine the role of the virulence of IBDV on the expression of chicken TLR3 (chTLR3). For this purpose, the levels of chTLR3 expression and its downstream effectors, Interferon β (IFN-β) and Interleukin 8 (IL-8), were detected and analyzed after infection of IBDV field isolates with differential virulence in vitro (chicken embryo fibroblast and/or chicken peripheral blood mononuclear cells) and in vivo (commercial Three-Yellow chicken)...
April 12, 2017: Viral Immunology
https://www.readbyqxmd.com/read/28381285/new-oligonucleotide-microarray-for-rapid-diagnosis-of-avian-viral-diseases
#14
Kulyaisan T Sultankulova, Nurlan S Kozhabergenov, Vitaliy M Strochkov, Yerbol D Burashev, Kamshat A Shorayeva, Olga V Chervyakova, Nurkuisa M Rametov, Nurlan T Sandybayev, Abylay R Sansyzbay, Mukhit B Orynbayev
BACKGROUND: We developed a new oligonucleotide microarray comprising 16 identical subarrays for simultaneous rapid detection of avian viruses: avian influenza virus (AIV), Newcastle disease virus (NDV), infection bronchitis virus (IBV), and infectious bursal disease virus (IBDV) in single- and mixed-virus infections. The objective of the study was to develop an oligonucleotide microarray for rapid diagnosis of avian diseases that would be used in the course of mass analysis for routine epidemiological surveillance owing to its ability to test one specimen for several infections...
April 5, 2017: Virology Journal
https://www.readbyqxmd.com/read/28351707/chemokine-receptor-ccr5-and-cxcr4-might-influence-virus-replication-during-ibdv-infection
#15
Changbo Ou, Qiuxia Wang, Yan Yu, Yanhong Zhang, Jinyou Ma, Xianghui Kong, Xingyou Liu
Both CCR5 and CXCR4 are important chemokine receptors and take vital role in migration, development and distribution of T cells, however, whether they will influence the process of T cell infiltration into bursa of Fabricius during infectious bursal disease virus (IBDV) infection is unclear. In the current study, CCR5 and CXCR4 antagonists, Maraviroc and AMD3100, were administrated into chickens inoculated with IBDV, and the gene levels of IBDV VP2, CCR5, CXCR4 and related cytokines were determined by real-time PCR...
March 27, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28332643/virus-mutations-and-their-impact-on-vaccination-against-infectious-bursal-disease-gumboro-disease
#16
A Boudaoud, B Mamache, W Tombari, A Ghram
Infectious bursal disease (also known as Gumboro disease) is an immunosuppressive viral disease specific to chickens. In spite of all the information amassed on the antigenic and immunological characteristics of the virus, the disease has not yet been brought fully under control. It is still prevalent in properly vaccinated flocks carrying specific antibodies at levels normally high enough to prevent the disease. Common causes apart, failure of vaccination against infectious bursal disease is associated mainly with early vaccination in flocks of unknown immune status and with the evolution of viruses circulating in the field, leading to antigenic drift and a sharp rise in pathogenicity...
December 2016: Revue Scientifique et Technique
https://www.readbyqxmd.com/read/28322935/early-pathogenesis-during-infectious-bursal-disease-in-susceptible-chickens-is-associated-with-changes-in-b-cell-genomic-methylation-and-loss-of-genome-integrity
#17
Nick A Ciccone, Lorraine P Smith, William Mwangi, Amy Boyd, Andrew J Broadbent, Adrian L Smith, Venugopal Nair
We propose a model by which an increase in the genomic modification, 5-hydroxymethylcytosine (5hmC), contributes to B cell death within the chicken bursa of Fabricus (BF) infected with infectious bursal disease virus (IBDV). Our findings indicate that, following an IBDV infection, Rhode Island Red (RIR) chickens have fewer surviving B cells and higher levels of 5hmC in the BF than the more resistant 15l line of birds. Elevated genomic 5hmC levels within the RIR BF are associated with markers of immune responses: infiltrating T cells and increased expression of CD40L, FasL and iNOS...
August 2017: Developmental and Comparative Immunology
https://www.readbyqxmd.com/read/28208594/immunomodulatory-and-anti-ibdv-activities-of-the-polysaccharide-aex-from-coccomyxa-gloeobotrydiformis
#18
Qiang Guo, Qiang Shao, Wenping Xu, Lei Rui, Ryo Sumi, Fumio Eguchi, Zandong Li
A number of polysaccharides have been reported to show immunomodulatory and antiviral activities against various animal viruses. AEX is a polysaccharide extracted from the green algae, Coccomyxa gloeobotrydiformis. The aim of this study was to examine the function of AEX in regulating the immune response in chickens and its capacity to inhibit the infectious bursal disease virus (IBDV), to gain an understanding of its immunomodulatory and antiviral ability. Here, preliminary immunological tests in vitro showed that the polysaccharide AEX can activate the chicken peripheral blood molecular cells' (PBMCs) response by inducing the production of cytokines and NO, promote extracellular antigen presentation but negatively regulate intracellular antigen presentation in chicken splenic lymphocytes, and promote the proliferation of splenic lymphocytes and DT40 cells...
February 10, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28098808/infectious-bursal-disease-virus-host-interactions-multifunctional-viral-proteins-that-perform-multiple-and-differing-jobs
#19
REVIEW
Yao Qin, Shijun J Zheng
Infectious bursal disease (IBD) is an acute, highly contagious and immunosuppressive poultry disease caused by IBD virus (IBDV). The consequent immunosuppression increases susceptibility to other infectious diseases and the risk of subsequent vaccination failure as well. Since the genome of IBDV is relatively small, it has a limited number of proteins inhibiting the cellular antiviral responses and acting as destroyers to the host defense system. Thus, these virulence factors must be multifunctional in order to complete the viral replication cycle in a host cell...
January 14, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28096615/molecular-characterization-of-field-infectious-bursal-disease-virus-isolates-from-nigeria
#20
Ijeoma O Nwagbo, Ismaila Shittu, Chika I Nwosuh, George O Ezeifeka, Frederick J C Odibo, Linda O Michel, Daral J Jackwood
AIM: To characterize field isolates of infectious bursal disease virus (IBDV) from outbreaks in nine states in Nigeria through reverse transcription polymerase chain reaction (RT-PCR) and sequence analysis of portions of the VP2 and VP1 genes and to determine the presence or absence of reassortant viruses. MATERIALS AND METHODS: A total of 377 bursa samples were collected from 201 suspected IBD outbreaks during 2009 to 2014 from nine states in Nigeria. Samples were subjected to RT-PCR using VP2 and VP1 gene specific primers, and the resulting PCR products were sequenced...
December 2016: Veterinary World
keyword
keyword
771
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"