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Trust but verify

Gerhard Hindricks, Niraj Varma, Salem Kacet, Thorsten Lewalter, Peter Søgaard, Laurence Guédon-Moreau, Jochen Proff, Thomas A Gerds, Stefan D Anker, Christian Torp-Pedersen
Aims: Remote monitoring of implantable cardioverter-defibrillators may improve clinical outcome. A recent meta-analysis of three randomized controlled trials (TRUST, ECOST, IN-TIME) using a specific remote monitoring system with daily transmissions [Biotronik Home Monitoring (HM)] demonstrated improved survival. We performed a patient-level analysis to verify this result with appropriate time-to-event statistics and to investigate further clinical endpoints. Methods and results: Individual data of the TRUST, ECOST, and IN-TIME patients were pooled to calculate absolute risks of endpoints at 1-year follow-up for HM vs...
June 7, 2017: European Heart Journal
P Boyer, F Lefebvre, C Siraudin, D Montjean, P Le Coz, M Gervoise-Boyer
OBJECTIVES: We organized a survey for in-vitro fertilization couples who beneficiated on self-preservation of part of the oocyte cohort. The main objective was to measure couples' satisfaction. Secondary objectives were; to identify how patients had been informed; to verify that the use of the ART technique met their expectations, and how they felt about oocyte or embryo freezing. METHODS: The data were collected by a questionnaire sent electronically to couples who had undergone partial vitrification of the oocyte cohort and at least one warming cycle...
April 2, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
C Robin Buell
No abstract text is available yet for this article.
March 2018: Plant Cell
Kyle Clark, Andrew George, Kristen Lloyd
No abstract text is available yet for this article.
March 2018: Home Healthcare Now
Isabell Binter, Christian Herold, Sixtus Allert
INTRODUCTION: Functioning communication is one of the basic elements of a trusting doctor-patient relationship. Good medical communication is more important than ever in times of increasing personnel and time constraints. The aim of this study was to examine to what extent medical communication has an influence on the initiation of arbitration procedures. MATERIAL AND METHODS: The analysis was based on arbitration cases of plastic surgery, which were processed and completed by the Arbitration Board for Medical Liability Issues of North Germany between 2005 and 2015...
December 2017: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
Phuong-Anh T Duong, Rebecca Neill, Matthew Zygmont
No abstract text is available yet for this article.
December 21, 2017: Journal of the American College of Radiology: JACR
Kristine L Florczak
In this column, the concept of betrayal is considered as it relates to publishing. The definition of betrayal is discussed, followed by information regarding the cost of publishing and why this led to the formation of open access publishing as a remedy. The Gold and Green Open Access models are examined along with why they may have inadvertently set the stage for predatory publishing practices. Finally, information will be provided on how to spot and avoid betrayal on the part of predatory publishers.
January 2018: Nursing Science Quarterly
Agnieszka Szadkowska, Andrzej Gawrecki, Arkadiusz Michalak, Dorota Zozulińska-Ziółkiewicz, Wojciech Fendler, Wojciech Młynarski
BACKGROUND AND AIMS: To evaluate the clinical accuracy of a flash glucose monitoring device FreeStyle Libre (FSL) among children with type 1 diabetes in real-world settings during a summer camp. MATERIALS AND METHODS: During a summer camp, children with type 1 diabetes (n = 79, aged 8-18 years) were provided with FSLs for 12 days. On days 3, 7, and 11 of the study, they underwent supervised glucose testing at 8 timepoints. Glycemia was estimated by using FSL and measured with a personal glucometer within a period of 2 min...
January 2018: Diabetes Technology & Therapeutics
Allan F Simpao, Jorge A Gálvez
No abstract text is available yet for this article.
February 2018: Anesthesiology
Lorraine T Dean, Shadiya L Moss, Anne Marie McCarthy, Katrina Armstrong
Background: Adjuvant therapy after breast cancer surgery decreases recurrence and increases survival, yet not all women receive and complete it. Previous research has suggested that distrust in medical institutions plays a role in who initiates adjuvant treatment, but has not assessed treatment completion, nor the potential mediating role of physician distrust. Methods: Women listed in Pennsylvania and Florida cancer registries, who were under the age of 65 when diagnosed with localized invasive breast cancer between 2005 and 2007, were surveyed by mail in 2007 to 2009...
December 2017: Cancer Epidemiology, Biomarkers & Prevention
Vasken Dilsizian, Y Chandrashekhar, Jagat Narula
No abstract text is available yet for this article.
May 2017: JACC. Cardiovascular Imaging
Jingyu Liu, Jiayu Chen, Nora I Perrone-Bizzozero, Jessica A Turner, Vince D Calhoun
Both schizophrenia (SZ) and bipolar disorder (BD) are highly heritable psychiatric disorders. The significant genomic risk loci are of great importance but with no guarantee of known functional impact and they cannot totally explain the genetic inheritance. In this study we present regional enrichment analyses across the genome, aiming to strike a balance between individual risk loci and integrated regional effects. Chromosomes were partitioned into 2 million base-pair regions (indicated by an underscore sign in the cytogenetic bands) on which enrichment tests are performed...
February 2018: Schizophrenia Research
Mitchell H Katz
No abstract text is available yet for this article.
February 1, 2017: JAMA Internal Medicine
Catia Contado, Roberto Argazzi, Vincenzo Amendola
Many advanced industrial and biomedical applications that use silver nanoparticles (AgNPs), require that particles are not only nano-sized, but also well dispersed, not aggregated and not agglomerated. This study presents two methods able to give rapidly sizes of monodispersed AgNPs suspensions in the dimensional range of 20-100nm. The first method, based on the application of Mie's theory, determines the particle sizes from the values of the surface plasmon resonance wavelength (SPRMAX), read from the optical absorption spectra, recorded between 190nm and 800nm...
November 4, 2016: Journal of Chromatography. A
O J Storebø, M Zwi, C R Moreira-Maia, M Skoog, G Camilla, D Gillies, E Simonsen, C Gluud
No abstract text is available yet for this article.
September 2016: Zeitschrift Für Kinder- und Jugendpsychiatrie und Psychotherapie
Christoph Haller
No abstract text is available yet for this article.
August 12, 2016: Journal of Thoracic and Cardiovascular Surgery
Ami Hale, Nanna Christiansen, Heather Calvert
AIM: To assess the time it takes for paediatric TTA and inpatient orders to be dispensed and sent to ward. This is to establish if the Trust is meeting an operational Key Performance Indicator (KPI). STANDARDS KPIS: ▸ 85% of urgent items (TTAs) dispensed within 1 hour.▸ 85% of non-urgent items (most inpatient orders) dispensed within 3 hrs. METHOD: To audit the time it takes for TTAs and inpatient orders to be screened, sent to dispensary, labelled, dispensed, checked, and leave dispensary...
September 2016: Archives of Disease in Childhood
Denis Fourches, Eugene Muratov, Alexander Tropsha
There is a growing public concern about the lack of reproducibility of experimental data published in peer-reviewed scientific literature. Herein, we review the most recent alerts regarding experimental data quality and discuss initiatives taken thus far to address this problem, especially in the area of chemical genomics. Going beyond just acknowledging the issue, we propose a chemical and biological data curation workflow that relies on existing cheminformatics approaches to flag, and when appropriate, correct possibly erroneous entries in large chemogenomics data sets...
July 25, 2016: Journal of Chemical Information and Modeling
T Banaschewski, M Gerlach, K Becker, M Holtmann, M Döpfner, M Romanos
Objective: A recent Cochrane review published by O. J. Storebo and colleagues (2015) raised substantial doubts about the benefit from stimulant medication with methylphenidate in the treatment of childhood ADHD due to the overall poor quality of studies. The systematic review thus contradicts all previous reviews and meta-analyses. Method: We here detail various examples of errors, inconsistencies, and misinterpretations in the review which led to false results and inadequate conclusions...
2016: Zeitschrift Für Kinder- und Jugendpsychiatrie und Psychotherapie
Rebekah Jayne McNaughton, Jean Adams, Janet Shucksmith
INTRODUCTION: Since the 1990 s strenuous attempts have been made to rebuild trust in childhood immunisations. This study aimed to understand if financial incentives (FI) or quasi-mandatory schemes (QMS), e.g. mandating immunisations for entry to universal services such as day care or school, might be acceptable interventions to increase immunisations uptake for preschool children. MATERIAL AND METHODS: Parents and carers of preschool children (n=91); health and other professionals (n=18); and those responsible for developing and commissioning immunisation services (n=6) took part in the study...
April 27, 2016: Vaccine
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