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https://www.readbyqxmd.com/read/28707864/oxidative-stress-antioxidants-and-lipid-profile-in-the-serum-and-saliva-of-individuals-with-coronary-heart-disease-is-there-a-link-with-periodontal-health
#1
Natheer H Al-Rawi, Alaa M Shahid
BACKGROUND: Oxidative stresses and dyslipidemia are an important risk factor in the development of coronary atherosclerotic complications like angina pectoris and myocardial infarction. The aim of this study was to find the relationship between the salivary lipid profile, lipid peroxidation and antioxidants and the periodontal health status of patients with acute coronary heart disease. METHODS: Forty s who had experienced a recent attack of angina pectoris or myocardial infarction and another 40 noncardiac patients matched for age, sex and residence (control) were recruited...
July 12, 2017: Minerva Stomatologica
https://www.readbyqxmd.com/read/28682270/secure-fusion-estimation-for-bandwidth-constrained-cyber-physical-systems-under-replay-attacks
#2
Bo Chen, Daniel W C Ho, Guoqiang Hu, Li Yu
State estimation plays an essential role in the monitoring and supervision of cyber-physical systems (CPSs), and its importance has made the security and estimation performance a major concern. In this case, multisensor information fusion estimation (MIFE) provides an attractive alternative to study secure estimation problems because MIFE can potentially improve estimation accuracy and enhance reliability and robustness against attacks. From the perspective of the defender, the secure distributed Kalman fusion estimation problem is investigated in this paper for a class of CPSs under replay attacks, where each local estimate obtained by the sink node is transmitted to a remote fusion center through bandwidth constrained communication channels...
July 3, 2017: IEEE Transactions on Cybernetics
https://www.readbyqxmd.com/read/28659323/wcig-o-acetyl-transferase-functionality-differentiates-pneumococcal-serotypes-35c-and-42
#3
K Aaron Geno, C Allen Bush, Mengnan Wang, Cheng Jin, Moon H Nahm, Jinghua Yang
Streptococcus pneumoniae expresses capsular polysaccharides (CPSs) to protect itself from opsonophagocytic killing. The genes responsible for capsules synthesized by the Wzy-dependent mechanism, which accounts for 96 of the 98 known pneumococcal capsule types, are encoded in a chromosomal region known as the cps locus. The nucleotide sequence in this region has been determined for all serotypes. In contrast, not all CPS structures have been defined. The structure of the serotype 35C polysaccharide was recently reported, but the presence of O-acetyltransferase genes in the serotype 35C cps locus suggested that it could be incomplete, as the reported structure contains no O-acetylation...
June 28, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28642597/a-single-amino-acid-polymorphism-in-the-glycosyltransferase-cpsk-defines-four-streptococcus-suis-serotypes
#4
David Roy, Taryn B T Athey, Jean-Philippe Auger, Guillaume Goyette-Desjardins, Marie-Rose Van Calsteren, Daisuke Takamatsu, Masatoshi Okura, Sarah Teatero, Martín Alcorlo, Juan A Hermoso, Mariela Segura, Marcelo Gottschalk, Nahuel Fittipaldi
The capsular polysaccharide (CPS) is the major virulence factor of the emerging zoonotic pathogen Streptococcus suis. CPS differences are also the basis for serological differentiation of the species into 29 serotypes. Serotypes 2 and 1/2, which possess identical gene content in their cps loci, express CPSs that differ only by substitution of galactose (Gal) by N-acetylgalactosamine (GalNAc) in the CPS side chain. The same sugar substitution differentiates the CPS of serotypes 14 and 1, whose cps loci are also identical in gene content...
June 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28628357/continuous-periosteal-strapping-sutures-cpss-for-fixation-of-osseous-grafts-with-resorbable-membranes-for-buccal-ridge-augmentation
#5
Tamir Shalev, Gregori M Kurtzman, Alon H Shalev, Deborah K Johnson, Mark Elias Kersten
GBR is a technique sensitive procedure that routinely involves placement of particulate bone with or without fixation screws and either a resorbable or a non-resorbable membrane. Grafting of the buccal-crestal aspect of the implant site can be particularly challenging as external pressure from the flap or occlusal forces may displace the graft laterally and apically resulting in deficient bone in the desired region. A novel technique for stabilizing a resorbable membrane and underlying particulate graft allowing for predictable bone grafting across multiple edentulous sites...
June 19, 2017: Journal of Oral Implantology
https://www.readbyqxmd.com/read/28616388/unusual-haemodynamics-in-two-dogs-and-two-cats-with-portosystemic-shunt-implications-for-distinguishing-between-congenital-and-acquired-conditions
#6
Mario Ricciardi
Extrahepatic porto-systemic shunt (PSS) in small animals can be congenital (CPSS) or acquired (APSS) as a consequence of portal hypertension (PH), and are distinguished on the bases of their anatomical pattern. A precise morphologic imaging assessment, along with clinical and histopathologic findings, is important for distinguishing patients with PH from those with congenital PSSs, which require different therapeutic approach. Expected findings in patients with PH are presence of ascites, multiple APSS, and a confirmed cause of portal flow obstruction...
2017: Open veterinary journal
https://www.readbyqxmd.com/read/28602988/characterization-of-hypericum-perforatum-polysaccharides-with-antioxidant-and-antimicrobial-activities-optimization-based-statistical-modeling
#7
Marzieh Heydarian, Hossein Jooyandeh, Behzad Nasehi, Mohammad Noshad
In this study, the extracting parameters of crude polysaccharides (CPSs) from the Hypericum perforatum (HP) including extraction time (ETi, 60-180min), extraction temperature (ETe, 60-90°C), and the water/solid ratio (W/S, 10-30 was optimized by using three-variable-three-level Box-Behnken design-response surface methodology (BBD-RSM) based on the single-factor experiments. The optimal extraction conditions were as follow: ETi 117.5min, ETe 74.28°C, and W/S 20.3:1. Under these conditions, the experimental yield was 6...
June 8, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28578199/structures-of-the-k35-and-k15-capsular-polysaccharides-of-acinetobacter-baumannii-luh5535-and-luh5554-containing-amino-and-diamino-uronic-acids
#8
Alexander S Shashkov, Bin Liu, Johanna J Kenyon, Anastasiya V Popova, Mikhail M Shneider, Sof'ya N Senchenkova, Nikolay P Arbatsky, Konstantin A Miroshnikov, Lei Wang, Yuriy A Knirel
Capsular polysaccharides were isolated from A. baumannii LUH5535 (K35 CPS) and LUH5554 (K15 CPS) and studied by 1D and 2D (1)H and (13)C NMR spectroscopy. The CPSs were found to consist of linear tetrasaccharide repeats (K units) containing 2-acetamido-2-deoxy-d-galacturonic acid (K35) or 2,3-diacetamido-2,3-deoxy-d-glucuronic acid (K15) and 2,4-diacetamido-2,4,6-trideoxy-d-glucose (both CPSs). The K35 unit includes three O-acetyl groups on different GalNAcA residues. A. baumannii LUH5535 and LUH5554 carry the KL35 and KL15 gene clusters, respectively, and putatively assigned functions of genes in these clusters were consistent with the CPS structures established...
May 25, 2017: Carbohydrate Research
https://www.readbyqxmd.com/read/28566369/t-cell-mediated-humoral-immune-responses-to-type-3-capsular-polysaccharide-of-streptococcus-pneumoniae
#9
Dustin R Middleton, Lina Sun, Amy V Paschall, Fikri Y Avci
Most pathogenic bacteria express surface carbohydrates called capsular polysaccharides (CPSs). CPSs are important vaccine targets because they are easily accessible and recognizable by the immune system. However, CPS-specific adaptive humoral immune responses can only be achieved by the covalent conjugation of CPSs with carrier proteins to produce glycoconjugate vaccines. We previously described a mechanism by which a model glycoconjugate vaccine can activate the adaptive immune system and demonstrated that the mammalian CD4(+) T cell repertoire contains a population of carbohydrate-specific T cells...
July 15, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28524752/widening-of-the-safe-trajectory-range-during-subaxial-cervical-pedicle-screw-placement-advantages-of-a-curved-pedicle-probe-and-laterally-located-starting-point-without-creating-a-funnel-shaped-hole
#10
Subum Lee, Junghan Seo, Moon Kyu Lee, Sang Ryong Jeon, Sung Woo Roh, Seung Chul Rhim, Jin Hoon Park
OBJECTIVE The small diameter of cervical pedicles and a large transverse cervical pedicle angle are challenges that have led spinal surgeons to investigate how they could achieve a wider safety trajectory and reduce the insertion angle during cervical pedicle screw (CPS) placement. In this paper, the authors detail the advantages of using a curved pedicle probe and a laterally located entry point for overcoming these challenges. METHODS From March 2012 to May 2016, the authors performed posterior cervical fusions using CPSs on 119 consecutive patients...
May 19, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28522734/voluntary-control-of-epileptiform-spike-wave-discharges-in-awake-rats
#11
Jeremy A Taylor, Krista M Rodgers, Florencia M Bercum, Carmen J Booth, F Edward Dudek, Daniel S Barth
Genetically inherited absence epilepsy in humans is typically characterized by brief (seconds) spontaneous seizures, which involve spike-wave discharges (SWDs) in the EEG and interruption of consciousness and ongoing behavior. Genetic (inbred) models of this disorder in rats have been used to examine mechanisms, comorbidities, and antiabsence drugs. SWDs have also been proposed as models of complex partial seizures (CPSs) following traumatic brain injury (post-traumatic epilepsy). However, the ictal characteristics of these rat models, including SWDs and associated immobility, are also prevalent in healthy outbred laboratory rats...
June 14, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28461446/phase-variable-changes-in-the-position-of-o-methyl-phosphoramidate-modifications-on-the-polysaccharide-capsule-of-campylobacter-jejuni-modulate-serum-resistance
#12
Brittany Pequegnat, Renee M Laird, Cheryl P Ewing, Christina L Hill, Eman Omari, Frederic Poly, Mario A Monteiro, Patricia Guerry
Campylobacter jejuni polysaccharide capsules (CPS) are characterized by the presence of nonstoichiometric O-methyl phosphoramidate (MeOPN) modifications. The lack of stoichiometry is due to phase variation at homopolymeric tracts within the MeOPN transferase genes. C. jejuni strain 81-176 contains two MeOPN transferase genes and has been shown previously to contain MeOPN modifications at the 2 and 6 positions of the galactose (Gal) moiety in the CPS. We demonstrate here that one of the two MeOPN transferases, encoded by CJJ81176_1435, is bifunctional and is responsible for the addition of MeOPN to both the 2 and the 6 positions of Gal...
July 15, 2017: Journal of Bacteriology
https://www.readbyqxmd.com/read/28425925/evaluation-of-the-immunomodulatory-properties-of-streptococcus-suis-and-group-b-streptococcus-capsular-polysaccharides-on-the-humoral-response
#13
Cynthia Calzas, Morgan Taillardet, Insaf Salem Fourati, David Roy, Marcelo Gottschalk, Hugo Soudeyns, Thierry Defrance, Mariela Segura
Streptococcus suis and group B Streptococcus (GBS) are encapsulated streptococci causing septicemia and meningitis. Antibodies (Abs) against capsular polysaccharides (CPSs) have a crucial protective role, but the structure/composition of the CPS, including the presence of sialic acid, may interfere with the generation of anti-CPS Ab responses. We investigated the features of the CPS-specific Ab response directed against S. suis serotypes 2 and 14 and GBS serotypes III and V after infection or immunization with purified native or desialylated CPSs in mice...
April 20, 2017: Pathogens
https://www.readbyqxmd.com/read/28419640/relationships-between-dispositional-mindfulness-self-acceptance-perceived-stress-and-psychological-symptoms-in-advanced-gastrointestinal-cancer-patients
#14
Wei Xu, Yuyang Zhou, Zhongfang Fu, Marcus Rodriguez
OBJECTIVE: Previous studies have shown that dispositional mindfulness is associated with less psychological symptoms in cancer patients. The present study investigated how dispositional mindfulness is related to psychological symptoms in advanced gastrointestinal cancer patients by considering the roles of self-acceptance and perceived stress. METHODS: A total of 176 patients with advanced gastrointestinal cancer were recruited to complete a series of questionnaires including Mindfulness Attention Awareness Scale (MAAS), Self-acceptance Questionnaire (SAQ), Chinese Perceived Stress Scale (CPSS) and General Health Questionnaire (GHQ)...
April 17, 2017: Psycho-oncology
https://www.readbyqxmd.com/read/28403590/efficacy-of-pollen-extract-in-association-with-group-b-vitamins-for-pain-relief-in-chronic-prostatitis-chronic-pelvic-pain-syndrome-a-survey-of-urologists-knowledge-about-its-clinical-application
#15
Giacomo Maria Pirola, Stefano Puliatti, Tommaso Bocchialini, Eugenio Martorana, Salvatore Micali, Giampaolo Bianchi
INTRODUCTION AND AIM OF THE STUDY: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPSS) is a pathology of high prevalence in Italian male population, difficult to diagnose and to treat and with poor response to conventional therapy. Aim of this study was to review the evidence of the literature about the therapeutic effects of a plant product containing flower pollen extracts and group B vitamins on symptoms resolution and amelioration of CP/CPPS patients' quality of life and to investigate the knowledge among practicing urologists about the clinical application of this product...
March 31, 2017: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28401743/portosystemic-shunt-as-a-cause-of-congenital-hyperinsulinemic-hypoglycemia
#16
Keisuke Yoshii, Masahiro Noda, Yasuhiro Naiki, Reiko Horikawa
Congenital hyperinsulinemic hypoglycemia (CHH) is characterized by the inappropriate secretion of insulin from pancreatic beta cells in the presence of hypoglycemia. We herein describe the case of a 5-month-old boy with CHH due to congenital portosystemic shunt (CPSS). Insulin secreted from pancreatic beta cells flows into the portal vein and is first metabolized in the liver. First-pass elimination of insulin in the liver leads to great decrease in insulin concentration by approximately 40-80% in humans. CPSS accounts for a large quantity of insulin delivery into the systemic circulation due to the lack of hepatic first-pass elimination...
April 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28390025/lead-biosorption-of-probiotic-bacteria-effects-of-the-intestinal-content-from-laying-hens
#17
Sicheng Xing, Jie Wang, Juan Boo Liang, Mohammad Faseleh Jahromi, Cui Zhu, Parisa Shokryazdan, Vito Laudadio, Vincenzo Tufarelli, Xindi Liao
This study investigated the effects and the possible mechanisms of intestinal content (IC) from laying hens on in vitro lead (Pb(2+)) biosorption of four probiotic bacterial strains (Bifidobacterium longum BB79, Lactobacillus paracasei Kgl6, Lactobacillus pentosus ITA23, and Lactobacillus acidipiscis ITA44). The total Pb(2+) removal capacity of the four probiotic strains, with and without capsule polysaccharides (CPSs), increased in the presence of IC compared to the control (without IC). SEM imaging revealed certain unidentified particles from the IC adhered on the surface of bacterial cells sorted out using flow cytometry...
May 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28382699/washout-ratio-in-the-hepatic-vein-measured-by-contrast-enhanced-ultrasonography-to-distinguish-between-inflammatory-and-noninflammatory-hepatic-disorders-in-dogs
#18
K Morishita, A Hiramoto, A Michishita, S Takagi, T Osuga, S Y Lim, K Nakamura, N Sasaki, H Ohta, M Takiguchi
BACKGROUND: Perflubutane microbubbles, a second-generation ultrasound contrast agent, are phagocytized by Kupffer cells. This characteristic may be useful to differentiate diffuse hepatic diseases in dogs. HYPOTHESIS/OBJECTIVES: To determine whether the washout ratio in the hepatic vein (HV) measured by contrast-enhanced ultrasonography (CEUS) can distinguish between inflammatory and noninflammatory hepatic disorders in dogs. ANIMALS: Forty-one client-owned dogs with hepatic disorders including 14 with hepatitis, 7 with primary hypoplasia of the portal vein (PHPV), 9 with congenital portosystemic shunt (cPSS), and 11 with other hepatopathy were enrolled...
May 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28372492/prenatally-diagnosed-congenital-portosystemic-shunts
#19
Bérengère Francois, Alain Lachaux, Fréderic Gottrand, Stéphanie De Smet
AIM: Congenital portosystemic shunts (CPSS) are rare, congenital malformations that are increasingly often discovered during the fetal period, and for which, the manifestations and evolution are poorly understood. The objective of this review is to describe the phenotype and evolution of forms diagnosed in the antenatal period. MATERIALS AND METHODS: We performed a systematic review of the literature cited in Pubmed between 1982 and 2016 for CPSS cases diagnosed during the fetal period...
April 20, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28370097/natural-history-of-chronic-myelomonocytic-leukemia-treated-with-hypomethylating-agents
#20
Ana Alfonso, Guillermo Montalban-Bravo, Koichi Takahashi, Elias J Jabbour, Tapan Kadia, Farhad Ravandi, Jorge Cortes, Zeev Estrov, Gautam Borthakur, Naveen Pemmaraju, Marina Konopleva, Carlos Bueso-Ramos, Sherry Pierce, Hagop Kantarjian, Guillermo Garcia-Manero
Hypomethylating agents (HMA) are the most commonly used therapeutic intervention in chronic myelomonocytic leukemia (CMML). Due to the lack of CMML-specific clinical trials, the impact of these agents in the natural history of CMML is not fully understood. We present the largest retrospective series of CMML (n = 151) treated with HMA. Mean age at diagnosis was 69 years (range 50-88). According to the CMML-specific prognostic scoring system (CPSS): 17 (15%) were low-risk, 45 (39%) intermediate-1 risk, 42 (36%) intermediate-2, and 12 (10%) high-risk...
March 28, 2017: American Journal of Hematology
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