Reto Auer, Anna Schoeni, Jean-Paul Humair, Isabelle Jacot-Sadowski, Ivan Berlin, Mirah J Stuber, Moa Lina Haller, Rodrigo Casagrande Tango, Anja Frei, Alexandra Strassmann, Philip Bruggmann, Florent Baty, Martin Brutsche, Kali Tal, Stéphanie Baggio, Julian Jakob, Nicolas Sambiagio, Nancy B Hopf, Martin Feller, Nicolas Rodondi, Aurélie Berthet
BACKGROUND: Electronic nicotine-delivery systems - also called e-cigarettes - are used by some tobacco smokers to assist with quitting. Evidence regarding the efficacy and safety of these systems is needed. METHODS: In this open-label, controlled trial, we randomly assigned adults who were smoking at least five tobacco cigarettes per day and who wanted to set a quit date to an intervention group, which received free e-cigarettes and e-liquids, standard-of-care smoking-cessation counseling, and optional (not free) nicotine-replacement therapy, or to a control group, which received standard counseling and a voucher, which they could use for any purpose, including nicotine-replacement therapy...
February 15, 2024: New England Journal of Medicine