keyword
MENU ▼
Read by QxMD icon Read
search

Vulvovaginal

keyword
https://www.readbyqxmd.com/read/29354612/probiotics-in-the-prevention-and-treatment-of-postmenopausal-vaginal-infections-review-article
#1
REVIEW
Jun-Mo Kim, Yoo Jin Park
Bacterial vaginosis (BV) and complicated vulvovaginal candidiasis (VVC) are frequently occurring vaginal infections in postmenopausal women, caused by an imbalance in vaginal microflora. Postmenopausal women suffer from decreased ovarian hormones estrogen and progesterone. A normal, healthy vaginal microflora mainly comprises Lactobacillus species (spp.), which act beneficially as a bacterial barrier in the vagina, interfering with uropathogens. During premenopausal period, estrogen promotes vaginal colonization by lactobacilli that metabolizing glycogen and producing lactic acid, and maintains intravaginal health by lowering the intravaginal pH level...
December 2017: Journal of Menopausal Medicine
https://www.readbyqxmd.com/read/29344000/visible-near-infrared-spectroscopic-assessment-of-urogenital-tissue-in-premenopausal-and-postmenopausal-women
#2
Miranda A Farage, Tom Cambron, Kan-Zhi Liu
Background: A clinical study was conducted to evaluate the feasibility of using visible and near-infrared (NIR) spectroscopy as a potential noninvasive measure of genital skin health in premenopausal and postmenopausal women. Methods: A total of 45 female subjects (aged 21-70 years), all of whom gave fully informed consent to participate, were enrolled in the study and assigned to 1 of 3 groups: 15 premenopausal (Pre-M), 15 postmenopausal receiving hormone replacement therapy (Post-M HRT), and 15 postmenopausal receiving no form of hormone replacement therapy (Post-M non-HRT)...
2018: Clinical Medicine Insights. Women's Health
https://www.readbyqxmd.com/read/29340981/nanolipid-gel-of-an-antimycotic-drug-for-treating-vulvovaginal-candidiasis-development-and-evaluation
#3
Dnyanesh Takalkar, Namita Desai
This paper focuses on the development and evaluation of mucoadhesive vaginal gel of fluconazole using nanolipid carriers to enhance tissue deposition in treating vulvovaginal candidiasis. Treatment of vulvovaginal candidiasis includes antimycotic agents prescribed for 1 to 7 days or longer, in relapse either orally or topically. The delivery of fluconazole as nanolipid carriers in vaginal gel can be proposed as suitable alternative to the existing conventional formulations to improve the patient acceptability, compliance and localized drug action...
January 16, 2018: AAPS PharmSciTech
https://www.readbyqxmd.com/read/29324620/diagnosis-and-treatment-of-vulvar-dermatoses
#4
Colleen K Stockdale, Lori Boardman
Vulvar symptoms of pain, dyspareunia, and pruritus are common and may significantly affect a woman's sense of well-being and sexual function. Despite this, vulvar symptoms are often underreported by women. When identified, however, vulvovaginal symptoms should be addressed by health care providers to optimize care. The evaluation of patients with vulvovaginal complaints begins with a thorough history and physical examination. Biopsy is indicated when concern exists for malignancy or the diagnosis is uncertain...
January 9, 2018: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29323627/a-phase-3-multicenter-prospective-open-label-study-to-evaluate-the-safety-of-a-single-dose-of-secnidazole-2%C3%A2-g-for-the-treatment-of-women-and-postmenarchal-adolescent-girls-with-bacterial-vaginosis
#5
Steven E Chavoustie, Janet K Gersten, Milroy J Samuel, Jane R Schwebke
BACKGROUND: A novel formulation of secnidazole is under development in the United States for the treatment of bacterial vaginosis (BV). Efficacy and safety of other formulations of secnidazole have been reported. The objective of this study is to evaluate the safety of a single-dose oral granule formulation of secnidazole in a U.S. population of women with BV. METHODS: In this open-label study, patients were enrolled based on the following criteria: off-white, thin, homogeneous vaginal discharge; vaginal pH ≥4...
January 11, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29315133/vaginal-health-of-postmenopausal-women-on-nutraceutical-containing-equol
#6
Salvatore Caruso, Stefano Cianci, Valentina Fava, Agnese M C Rapisarda, Silvia Cutello, Antonio Cianci
OBJECTIVE: The aim of the study was to evaluate the effects of nutraceuticals containing equol on vaginal health of postmenopausal women with vulvovaginal symptoms and dyspareunia. METHODS: One hundred twenty-six natural postmenopausal women on +1b +1c (2 and 3-6 y after the final menstrual period, respectively) of the Stages of Reproductive Aging Workshop were enrolled in a nonrandomized trial. Of these, 72 women accepted to use nutraceutical (group A). The remaining 54 women refused the treatment and participated as the control group (group B)...
January 8, 2018: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29302986/propolis-increases-neutrophils-response-against-candida-albicans-through-the-increase-of-reactive-oxygen-species
#7
Nayara Cristina Alves de Lima, Bianca Altrao Ratti, Patrícia de Souza Bonfim Mendonça, Gilson Murata, Raphaela Regina Araujo Pereira, Celso Vataru Nakamura, Marcia Edilaine Lopes Consolaro, Terezinha Inez Estivalet Svidzinski, Elaine Hatanaka, Marcos Luciano Bruschi, Sueli de Oliveira Silva
AIM: To investigate whether Brazilian green propolis improves the immune response against recurrent form isolate recurrent vulvovaginal candidiasis (RVVC) caused by Candida albicans by increasing neutrophil oxidative burst. MATERIALS & METHODS: We evaluated oxidant species production, oxygen consumption, microbicidal activity and myeloperoxidase activity in neutrophils previously treated with propolis and activated with different isolates of C. albicans (RVVC), vulvovaginal candidiasis, asymptomatic isolates and the reference strain...
January 5, 2018: Future Microbiology
https://www.readbyqxmd.com/read/29290220/diagnosis-and-management-of-vulvodynia-in-postmenopausal-women
#8
REVIEW
Pedro Vieira-Baptista, Gilbert Donders, Lynnette Margesson, Libby Edwards, Hope K Haefner, Faustino R Pérez-López
Vulvodynia, defined as vulvar pain or burning sensation for more than 3 months, without an identifiable cause, can occur at any age. In this paper, the authors address the classification, epidemiology, etiology, diagnosis, and treatment of this condition, focusing on postmenopausal women. In postmenopausal women, vulvar pain and dyspareunia can often be attributed to low levels of estrogen resulting in vulvovaginal atrophy. While correction of vulvovaginal atrophy is an important part of the management of these patients, it will usually be insufficient to manage vulvodynia...
February 2018: Maturitas
https://www.readbyqxmd.com/read/29286987/a-systematic-review-of-intravaginal-testosterone-for-the-treatment-of-vulvovaginal-atrophy
#9
Robin J Bell, Farwa Rizvi, Rakabul M Islam, Susan R Davis
OBJECTIVES: Intravaginal testosterone has emerged as a potential treatment for vulvovaginal atrophy (VVA) in women, in general, and women taking an aromatase inhibitor (AI). A systematic review of the literature was undertaken to determine whether available clinical trial data support efficacy and safety of intravaginal testosterone for the treatment of VVA. METHODS: Scopus, MEDLINE, EMBASE, and the Cochrane Library databases were systematically searched on July 26, 2017, for human studies published in English of clinical trials of intravaginal testosterone...
December 28, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29286986/fractional-microablative-co2-laser-in-breast-cancer-survivors-affected-by-iatrogenic-vulvovaginal-atrophy-after-failure-of-nonestrogenic-local-treatments-a-retrospective-study
#10
Tiziana Pagano, Pasquale De Rosa, Roberta Vallone, Francesco Schettini, Grazia Arpino, Mario Giuliano, Rossella Lauria, Irene De Santo, Alessandro Conforti, Alessandra Gallo, Giovanni Nazzaro, Sabino De Placido, Mariavittoria Locci, Giuseppe De Placido
OBJECTIVE: Vulvovaginal atrophy (VVA) is a condition frequently observed in menopause. Its symptoms can significantly affect the quality of life of patients. Since VVA is related to estrogen deficiency, chemotherapy and hormone therapy for breast cancer (BC) might cause VVA by inducing menopause. Given the lack of effective treatment for VVA in BC survivors, we retrospectively evaluated the efficacy and tolerability of fractional microablative CO2 laser therapy in these patients. METHODS: We treated 82 BC survivors with three cycles of CO2 laser after failure of topical nonestrogenic therapy...
December 28, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29279857/corrigendum-to-comparison-between-fluconazole-with-oral-protexin-combination-and-fluconazole-in-the-treatment-of-vulvovaginal-candidiasis
#11
S Nouraei, S Amir Ali Akbari, M Jorjani, H Alavi Majd, M Afrakhteh, A Ghafoorian, H Tafazzoli Harandi
[This corrects the article DOI: 10.5402/2012/375806.].
2017: International Scholarly Research Notices
https://www.readbyqxmd.com/read/29276058/robot-assisted-anterior-pelvic-exenteration-in-vulvovaginal-malignant-melanoma
#12
Se Ik Kim, Seungmee Lee, Chang Wook Jeong, Hee Seung Kim
OBJECTIVE: Melanomas of the vulva and vagina are rare, and surgery is the gold standard of treatment [1, 2]. Since recent studies have reported pelvic exenteration by using robotic surgical system [3, 4], we showed the surgical procedures of robot-assisted anterior pelvic exenteration (rAPE) with ileal conduit urinary diversion for vulvovaginal malignant melanoma. METHODS: A 55-year-old woman who received vaginal wall resection due to vaginal malignant melanoma 8months before was referred...
December 21, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/29259175/nlrp3-inflammasome-is-a-key-player-in-human-vulvovaginal-disease-caused-by-candida-albicans
#13
Elena Roselletti, Stefano Perito, Elena Gabrielli, Antonella Mencacci, Eva Pericolini, Samuele Sabbatini, Antonio Cassone, Anna Vecchiarelli
The expression of host inflammatory and Candida albicans putative virulence factors was studied in women with vulvovaginal candidiasis (VVC; twenty) or colonized by the fungus but asymptomatic (carriers; fifteen) or non-colonized asymptomatic (ten subjects). Overexpression of genes encoding NLRP3 and caspase-1 inflammasome components sharply differentiated VVC patients from asymptomatic colonized or non-colonized women. Inflammasome expression was coupled with neutrophils recruitment in the vagina of VVC women and IL-1β and IL-8 production...
December 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29245055/high-proportion-of-abnormal-pap-smear-tests-and-cervical-dysplasia-in-women-with-cystic-fibrosis
#14
Christine Rousset-Jablonski, Quitterie Reynaud, Raphaëlle Nove-Josserand, Isabelle Ray-Coquard, Yahia Mekki, François Golfier, Isabelle Durieu
OBJECTIVES: Insufficient gynecological follow-up and cervical screening has been reported in women with cystic fibrosis (CF). Some of these patients will require a pulmonary transplantation, known to be associated with a higher risk of cervical dysplasia. The aim of this study was to explore the results of cervical screening in adult women with CF, and to report the prevalence of abnormal pap smear tests in this population. STUDY DESIGN: We retrospectively analyzed medical records of sexually active women with CF who attended a gynecological consultation in Lyon University CF referral center between June 2014 and December 2015...
December 9, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29236848/histopatology-of-the-reproductive-tract-of-nellore-pubertal-heifers-with-genital-ureaplasmosis
#15
Regiani Pôrto, Benedito Oliveira Filho, Henrique Ferraz, Luciano Caixeta, Marco Antonio Viu, Maria Lúcia Gambarini
In order to study and characterize the lesions in the reproductive tract of Nellore heifers naturally infected with Ureaplasma diversum and presenting granular vulvovaginitis syndrome (GVS), fragments of uterine tube, uterus, cervix, vagina and vulva of 20 animals were evaluated. The macroscopic lesions of the vulvovaginal mucosa were classified in scores of "1" mild, until "4", severe inflammation and pustular or necrotic lesions. The histopathological evaluation was performed using scores of "1" to "4", according to the inflammatory alterations...
December 7, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/29223972/intravaginal-boric-acid-is-it-an-alternative-therapeutic-option-for-vaginal-trichomoniasis
#16
Nicola Thorley, Jonathan Ross
OBJECTIVES: Trichomoniasis, caused by Trichomonas vaginalis (TV), is the most common curable sexually transmitted infection worldwide. Current guidance in the UK is to treat TV with a nitroimidazole antibiotic. The high prevalence of TV, high rate of antibiotic resistance and limited tolerability to nitroimidazoles suggest that alternative treatment regimens are needed. Intravaginal boric acid (BA) has been used safely for the treatment of candida vulvovaginitis and bacterial vaginosis, and in vitro studies suggest BA is active against TV...
December 9, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/29208876/disease-pattern-among-children-attending-pediatric-outpatient-department-in-community-based-medical-college-hospital-bangladesh
#17
M Begum, M K Khan, M T Hossain, M Y Ali, F S Alam, S S Dipu, A H Hasan, M Nasrin
Disease pattern is based on socio-demographic characteristics, comprehensive health care services, and environmental variables like water supply, basic sanitation and housing, illness behavior like quick decision to arrive at health care facility, and treatment behavior like the modality of treatment they receive. The descriptive cross-sectional study was conducted during the period of January 2014 to December 2015. The study was carried out among 310 purposively selected children attended at Pediatric Outpatient department of Community Based Medical College Hospital, Bangladesh...
October 2017: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/29206779/concentration-range-of-serum-sex-steroids-in-normal-postmenopausal-women-and-those-with-diagnosis-of-vulvovaginal-atrophy
#18
Yuyong Ke, Alain Bélanger, Jean-Nicolas Simard, Renaud Gonthier, Céline Martel, Mario Vaillancourt, Fernand Labrie
OBJECTIVE: The aim of the study was to determine the range of serum sex-related steroids in normal postmenopausal women and in women of the same age with a diagnosis of vulvovaginal atrophy (VVA). METHODS: Validated mass spectrometry-based assays coupled to gas or liquid chromatography were used over a 10-year period for steroid measurements. Serum samples were obtained in up to 1,512 women aged 55 to 65 years. RESULTS: Serum estrone sulfate (E1S) and androsterone glucuronide (ADT-G), the main metabolites of estrogens and androgens, respectively, were 16...
December 4, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29203543/a-novel-mechanism-behind-the-immunopathogenesis-of-vulvovaginal-candidiasis-neutrophil-anergy
#19
Junko Yano, Brian M Peters, Mairi C Noverr, Paul L Fidel
For over three decades, investigators have studied the pathogenesis of vulvovaginal candidiasis (VVC) and recurrent VVC (RVVC) through clinical studies and animal models. While there was considerable consensus that susceptibility was not associated with any apparent deficiencies in adaptive immunity, protective immune mechanisms and the role of innate immunity remained elusive. It was not until an innovative live challenge design was conducted in women that a fuller understanding of the natural history of infection/disease was achieved...
December 4, 2017: Infection and Immunity
https://www.readbyqxmd.com/read/29202940/genitourinary-syndrome-of-menopause-management-strategies-for-the-clinician
#20
REVIEW
Stephanie S Faubion, Richa Sood, Ekta Kapoor
Genitourinary syndrome of menopause (GSM), previously known as atrophic vaginitis or vulvovaginal atrophy, affects more than half of postmenopausal women. Caused by low estrogen levels after menopause, it results in bothersome symptoms, including vaginal dryness, itching, dyspareunia, urinary urgency and increased frequency, and urinary tract infections. Even though women with GSM can have sexual dysfunction that interferes with partner relationships, women are often embarrassed to seek treatment, and health care professionals do not always actively screen for GSM...
December 2017: Mayo Clinic Proceedings
keyword
keyword
77067
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"