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https://www.readbyqxmd.com/read/28934912/role-of-female-intimate-hygiene-in-vulvovaginal-health-global-hygiene-practices-and-product-usage
#1
Ying Chen, Elizabeth Bruning, Joseph Rubino, Scott E Eder
Women use various feminine hygiene products, often as part of their daily cleansing routine; however, there is a paucity of published medical literature related to the external vulva and how personal hygiene practices can affect it. This review article provides background information on the physiological changes that occur during women's lives and reviews the relevance of transient and resident microbiota as they relate to common vaginal and vulvar disorders. It also discusses the need for female intimate hygiene, common practices of feminine hygiene from a global perspective, and the potential benefits of using suitable external, topical feminine vulvar washes to minimize the risk of vulvovaginal disorders and to improve overall intimate health in women around the world...
September 1, 2017: Women's Health
https://www.readbyqxmd.com/read/28934376/managing-menopausal-symptoms-and-associated-clinical-issues-in-breast-cancer-survivors
#2
Richard J Santen, Cynthia A Stuenkel, Susan R Davis, JoAnn V Pinkerton, Anne Gompel, Mary Ann Lumsden
Objective: Review evidence to guide the management of menopausal signs and symptoms in women after breast cancer and make recommendations accordingly. Evidence: Randomized controlled clinical trials, observational studies, evidence- based guidelines, and expert opinion from professional societies. Background: Several symptoms and clinical problems associated with estrogen depletion -sleep disorders, vulvovaginal atrophy (VVA), vasomotor symptoms (VMS), mood changes, depressive symptoms, cardiovascular disease, osteopenia and osteoporosis- confront the estimated 9...
August 2, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28927766/vulvovaginitis-presentation-of-more-common-problems-in-pediatric-and-adolescent-gynecology
#3
REVIEW
Meredith Loveless, Ohmar Myint
Vulvovaginitis is one of the most common gynecological complaints presenting in the pediatric and adolescent female. The common causes of vulvovaginitis in the pediatric patient differ than that considered in adolescent females. When a child present with vulvar itching, burning and irritation the most common etiology is non-specific and hygiene measures are recommended. However these symptoms can mimic more serious etiologies including infection, labial adhesion, lichen sclerosis, pinworms and foreign body must be considered...
September 5, 2017: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28927765/recurrent-vulvovaginal-candidiasis
#4
REVIEW
Freida Blostein, Elizabeth Levin-Sparenberg, Julian Wagner, Betsy Foxman
PURPOSE: Recurrent vulvovaginal candidiasis (RVVC), multiple episodes of vulvovaginal candidiasis (VVC; vaginal yeast infection) within a 12-month period, adversely affects quality of life, mental health, and sexual activity. Diagnosis is not straightforward, as VVC is defined by the combination of often nonspecific vaginal symptoms and the presence of yeast-which is a common vaginal commensal. Estimating the incidence and prevalence is challenging: most VVC is diagnosed and treated empirically, the availability for purchase of effective therapies over the counter enables self-diagnosis and treatment, and the duration of the relatively benign VVC symptoms is short, introducing errors into any estimates relying on medical records or patient recall...
August 15, 2017: Annals of Epidemiology
https://www.readbyqxmd.com/read/28927649/coping-with-pain-in-intimate-situations-applying-the-avoidance-endurance-model-to-women-with-vulvovaginal-pain
#5
I K Flink, L Engman, M M Ter Kuile, J Thomtén, S J Linton
BACKGROUND AND AIMS: Chronic vulvovaginal pain is strikingly common and has a serious impact on women's lives. Nevertheless, there are few longitudinal studies focusing on mechanisms involved in the pain development. One area of interest is how women cope with sexual activities and how this affects their pain. In this study, avoidance and endurance coping behaviors were explored as possible mediators of the relation between catastrophizing and pain, cross-sectionally and longitudinally...
September 15, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/28926514/a-randomized-multicenter-double-blind-study-to-evaluate-the-safety-and-efficacy-of-estradiol-vaginal-cream-0-003-in-postmenopausal-women-with-dyspareunia-as-the-most-bothersome-symptom
#6
Robin Kroll, David F Archer, Yuhua Lin, Vilma Sniukiene, James H Liu
OBJECTIVE: Vulvovaginal atrophy (VVA) is characterized by vaginal changes, dyspareunia, and itching/irritation. Efficacy and safety of a lower-dose estradiol vaginal cream (0.003%) were evaluated in postmenopausal women with VVA-related dyspareunia. METHODS: This was a phase 3, randomized, double-blind, placebo-controlled study. Sexually active postmenopausal women with moderate-severe dyspareunia as the most bothersome symptom, ≤5% vaginal superficial cells, and vaginal pH >5...
September 18, 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/28922940/linear-lichen-planus-continuum-from-skin-to-mucosa
#7
Mikhin George Thomas, Ambooken Betsy
Lichen planus (LP) is a chronic inflammatory disorder that most commonly affects middle-aged individuals. LP involves the skin and/or mucous membranes, including oral, vulvovaginal, esophageal, laryngeal, and conjunctival mucosa. Linear LP, a rare distinct variant of LP, is characterised by pruritic eruption of lichenoid and violaceous papules in a linear distribution. We report an unusual presentation of linear LP in a 14-year-old child that extended from the left anterior nares to upper lip and into the oral mucosa up to the upper gum margin...
September 1, 2017: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/28920516/high-glucose-mediated-overexpression-of-icam-1-in-human-vaginal-epithelial-cells-increases-adhesion-of-candida-albicans
#8
Hiroshige Mikamo, Yuka Yamagishi, Hiroyuki Sugiyama, Hisato Sadakata, Shun Miyazaki, Takako Sano, Tsutomu Tomita
To investigate the involvement of ICAM-1 in the adhesion of Candida to the genitourinary epithelial cells in high glucose, we examined the adhesion of Candida albicans or Candida glabrata to human vaginal epithelial cells (VK2/E6E7) or human vulvovaginal epidermal cells (A431). These cells were cultured in 100, 500 or 3000 mg/dL glucose for three days and inoculated with Candida for 60 minutes. Followed by, adhering of Candida to the cells, which were counted. While the adhesion of Candida albicans to VK2/E6E7 significantly increased in the high glucose, A431 did not...
September 18, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28919147/pediatric-resident-training-in-prepubertal-vulvar-conditions
#9
Monica Rosen, Veronica I Alaniz, Emily K Kobernik, Stephanie Booms, Yolanda R Smith, Elisabeth H Quint
STUDY OBJECTIVE: To assess pediatric resident training in diagnosing and managing prepubertal gynecologic conditions. DESIGN: Voluntary 32-question survey emailed to participants. SETTING: Email contact through the American Academy of Pediatrics listserve. PARTICIPANTS: 7075 U.S. pediatrics and combined internal medicine-pediatric residents. INTERVENTIONS: Descriptive analysis including Chi-square tests was performed on survey results...
September 14, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/28911197/contribution-of-tlr2-pathway-in-the-pathogenesis-of-vulvovaginal-candidiasis
#10
María Soledad Miró, Emilse Rodríguez, Cecilia Vigezzi, Paula Alejandra Icely, Luciana N García, Nahuel Painetti, Cristina A Maldonado, Fernando Oscar Riera, Juan Pablo Caeiro, Claudia Elena Sotomayor
Candida albicans is the prevalent etiological agent in acute vulvovaginal infection and the most severe chronic condition known as recurrent vulvovaginal candidiasis (VVC). A critical role of local innate immunity in defense and pathogenesis of vaginal infection by Candida is proposed. The fungal recognition by the innate immune receptor is an essential step for the induction of local responses including cytokines and antimicrobial peptides (AMPs) production for host protection. Using TLR2-deficient mice, we characterized the early innate immune response during VVC...
September 29, 2017: Pathogens and Disease
https://www.readbyqxmd.com/read/28904795/cervical-superficial-myofibroblastoma-case-report-and-review-of-the-literature
#11
Mohamed Abdelaziz, Noura Eziba, Suash Sharma, Daniel Kleven, Ayman Al-Hendy
Superficial myofibroblastoma of the lower female genital tract is a rare benign, recently recognized neoplasm that mostly affects the vulvovaginal area. Our report discusses a case of cervical superficial myofibroblastoma of the lower female genital tract in a 45-year-old patient who is presented with menometrorrhagia. On examination, she had multiple uterine fibroids and a circumscribed submucosal mass lesion involving the anterior lip of cervix. At hysterectomy, histopathological examination of the cervical mass revealed a relatively hypocellular tumor consisted of bland spindled and stellate cells...
2017: SAGE open medical case reports
https://www.readbyqxmd.com/read/28894392/fractional-co2-laser-treatment-for-vulvovaginal-atrophy-symptoms-and-vaginal-rejuvenation-in-perimenopausal-women
#12
César Arroyo
BACKGROUND: This study investigated a novel fractional carbon dioxide (CO2) laser for treatment of symptoms associated with vulvovaginal atrophy (VVA) in perimenopausal women. METHODS: The study included 21 perimenopausal women (mean age 45±7 years) treated three times by CO2 laser resurfacing and coagulation of the vaginal canal tissue and mucosal tissue of the introitus. Vaginal health index (VHI) scores were computed by the investigator at baseline and follow-ups...
2017: International Journal of Women's Health
https://www.readbyqxmd.com/read/28885410/distressing-sexual-function-at-midlife-unmet-needs-practical-diagnoses-and-available-treatments
#13
James A Simon, Vanessa A Lukas
Female sexual dysfunction (FSD) is characterized as chronic sexual symptoms that manifest with personal distress in the domains of desire, arousal, orgasm, and pain. Extensive epidemiologic evidence estimates that almost 50% of perimenopausal and postmenopausal women experience FSD. Screening for FSD is not readily conducted and patient-physician discussion of sexuality is limited by the lack of physician training on the topic and by the patient-held belief that sexual issues are not medical in nature. The purpose of this commentary is to provide clinicians with a framework to approach the discussion of FSD, to clinically identify FSD through patient symptoms and physical signs, and to manage FSD in perimenopausal and postmenopausal patients with the available U...
September 5, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28876387/assessment-of-cow-and-farm-level-risk-factors-associated-with-ureaplasma-diversum-in-pasture-based-dairy-systems-a-field-study
#14
Josefa M Nascimento-Rocha, Benedito D DE Oliveira, Emannuel Arnhold, Regiani N G Pôrto, Svetlana F Lima, Maria Lucia Gambarini
Potential risk factors for Ureaplasma diversum in the vaginal mucus of 1,238 dairy cows were included in a multivariate logistic regression model, based on the cow level (i.e., granular vulvovaginitis [+GVV], yearly milk production [4500 kg or more], pregnancy, predominance of Bos taurus [+Bos Taurus], score of corporal condition [at least 2.5], concomitant positivity for Escherichia coli [+E.coli]), and farm level i.e., milking room hygiene (-Milking room), dunghill location, and replacement female). Ureaplasma diversum was present in 41...
August 31, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28868834/recurrent-vulvovaginal-candidiasis-could-it-be-related-to-cell-mediated-immunity-defect-in-response-to-candida-antigen
#15
Zahra Talaei, Saba Sheikhbahaei, Vajihe Ostadi, Mazdak Ganjalikhani Hakemi, Mohsen Meidani, Elham Naghshineh, Majid Yaran, Alireza Emami Naeini, Roya Sherkat
Background: Recurrent vulvovaginal candidiasis (RVVC) is a common cause of morbidity affecting millions of women worldwide. Patients with RVVC are thought to have an underlying immunologic defect. This study has been established to evaluate cell-mediated immunity defect in response to candida antigen in RVVC cases. MATERIALS AND METHODS: Our cross-sectional study was performed in 3 groups of RVVC patients (cases), healthy individuals (control I) and known cases of chronic mucocutaneous candidiasis (CMC) (control II)...
October 2017: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/28867602/a-phase-3-double-blind-placebo-controlled-study-of-the-effectiveness-and-safety-of-single-oral-doses-of-secnidazole-2-g-for-the-treatment-of-women-with-bacterial-vaginosis
#16
Jane R Schwebke, Franklin G Morgan, William Koltun, Paul Nyirjesy
BACKGROUND: A novel single oral dose granule formulation of secnidazole 2 g, a 5-nitroimidazole with a longer half-life (∼17 hours) than metronidazole (∼8 hours), is being developed to treat bacterial vaginosis (BV). OBJECTIVE: To evaluate the effectiveness and safety of single-dose secnidazole 2 g compared to placebo for the treatment of women with BV. STUDY DESIGN: 189 women with BV were randomized 2:1 to receive a single oral dose of secnidazole 2 g (N=125) or matched placebo (N=64) at 21 centers in the US...
August 31, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28866964/effects-of-soy-isoflavones-on-the-concentration-of-hyaluronic-acid-in-the-vagina-of-type-1-diabetic-rats
#17
A A F Carbonel, P D Azevedo Lima, J J Lim, F Teixeira Borges, G Rodrigues da Silva Sasso, L F Portugal Fuchs, R S Simões, E Chada Baracat, J M Soares, M J Simões
OBJECTIVE: To assess the effects of isoflavones and 17β-estradiol on the vaginal epithelium extracellular matrix and hyaluronic acid (HA) in the diabetic rat model. METHODS: Sixty adult, virgin, female rats underwent ovariectomy, then randomization into six groups of ten animals each: GI, sham ovariectomized control animals; GII, sham ovariectomized control diabetic animals; GIII, control ovariectomized rats receiving propylene glycol vehicle; GIV, control ovariectomized diabetic animals receiving propylene glycol vehicle; GV, diabetic ovariectomized animals treated with soy isoflavones (150 mg/kg by gavage); GVI, ovariectomized diabetic rats treated with estrogen (17β-estradiol, 10 mg/kg, subcutaneously)...
September 2, 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28866727/long-term-reliability-of-fractioned-co2-laser-as-a-treatment-for-vulvovaginal-atrophy-vva-symptoms
#18
Annalisa Pieralli, Claudia Bianchi, Manuela Longinotti, Serena Corioni, Noemi Auzzi, Angelamaria Becorpi, Maria Grazia Fallani, Giuseppe Cariti, Felice Petraglia
PURPOSE: The aim of this study was to evaluate long-term effects of the fractional CO2 laser for the treatment of vulvovaginal atrophy (VVA) symptoms. METHODS: Women presenting with VVA symptoms and meeting inclusion criterion were enrolled to fractioned CO2 laser therapy. Patient's satisfaction was measured on five-point Likert scale at 4 weeks and 6, 12, 18, 24 months after treatment by interview and clinical examination for vaginal livability. RESULTS: 184 patients constituted the final study group: 128 women were spontaneous menopause and 56 were oncological menopause...
September 2, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28861766/in-vitro-probiotic-properties-of-lactobacillus-salivarius-mg242-isolated-from-human-vagina
#19
Chang-Ho Kang, Seul Hwa Han, YongGyeong Kim, Nam-Soo Paek, Jae-Seong So
Vulvovaginal candidiasis (VVC) is a very common infection worldwide that is mainly caused by Candida albicans. In a previous study, we showed that Lactobacillus salivarius MG242 has anti-Gardnerella vaginalis activity. In this study, we investigated the potential of using L. salivarius MG242 for biocontrol of C. albicans. In line with the results from a spot overlay assay, MG242 inhibited the growth of C. albicans by 99.99 ± 0.01% in co-culture, suggesting that L. salivarius MG242 has the potential to be developed into a probiotic formula to treat or prevent VVC...
August 31, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/28858028/prevalence-of-sexual-symptoms-in-relation-to-menopause-in-women-in-asia-a-systematic-review
#20
Rakibul M Islam, Robin J Bell, Susan R Davis
OBJECTIVE: This systematic review of the literature was undertaken to investigate the prevalence of sexual symptoms in women in Asia in relation to their menopause status. METHODS: MEDLINE, EMBASE, PsycINFO, CINAHL, SCOPUS, and Google scholar were searched systematically for relevant population-based prevalence studies published between 1988 and 2016. The included studies were assessed for risk of bias using a risk-of-bias tool developed explicitly for the systematic review of prevalence studies...
August 28, 2017: Menopause: the Journal of the North American Menopause Society
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