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Paediatric sleep

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https://www.readbyqxmd.com/read/28599949/quetiapine-extended-release-versus-aripiprazole-in-children-and-adolescents-with-first-episode-psychosis-the-multicentre-double-blind-randomised-tolerability-and-efficacy-of-antipsychotics-tea-trial
#1
Anne Katrine Pagsberg, Pia Jeppesen, Dea Gowers Klauber, Karsten Gjessing Jensen, Ditte Rudå, Marie Stentebjerg-Olesen, Peter Jantzen, Simone Rasmussen, Eva Ann-Sofie Saldeen, Maj-Britt Glenn Lauritsen, Niels Bilenberg, Anne Dorte Stenstrøm, Louise Nyvang, Sarah Madsen, Thomas M Werge, Theis Lange, Christian Gluud, Maria Skoog, Per Winkel, Jens Richardt M Jepsen, Birgitte Fagerlund, Christoph U Correll, Anders Fink-Jensen
BACKGROUND: Head-to-head trials to guide antipsychotic treatment choices for paediatric psychosis are urgently needed because extrapolations from adult studies might not be implementable. In this superiority trial with two-sided significance testing, we aimed to compare the efficacy and safety of quetiapine-extended release (quetiapine-ER) versus aripiprazole in children and adolescents with first-episode psychosis, to determine whether differences between the two treatments were sufficient to guide clinicians in their choice of one drug over the other...
June 6, 2017: Lancet Psychiatry
https://www.readbyqxmd.com/read/28590549/association-between-breast-feeding-and-paediatric-sleep-disordered-breathing-a-systematic-review
#2
REVIEW
Cecilia Ponce-Garcia, Ivonne Angelica Hernandez, Paul Major, Carlos Flores-Mir
BACKGROUND: Breast feeding has been suggested as a potential protective factor against childhood snoring and sleep disordered breathing (SDB). SDB can have major health consequences. The objective of this systematic review is to synthesise the available literature concerning any potential association between infant feeding methods and SDB in young children. METHODS: Five electronic databases were searched. All searches were inclusive until August 5, 2016. Two authors independently reviewed potentially relevant articles for eligibility...
June 7, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28576514/ultrasonographic-assessment-of-tonsillar-volume-in-children
#3
Panagiotis Asimakopoulos, David J L Pennell, Constantinos Mamais, Derek Veitch, Samuel Stafrace, Thomas Engelhardt
OBJECTIVES: Adenotonsillar hypertrophy in children is the most common anatomical abnormality associated with obstructive sleep apnoea. Perioperative complications associated with adenotonsillectomy are more common in children with severe obstructive sleep apnoea. An objective preoperative method to determine the size of tonsils is missing. This study assessed the validity of ultrasound as a tool for measuring tonsillar size in children. METHODS: Single-institution prospective study of twenty-six children aged 2-6 years who underwent elective bilateral tonsillectomy...
April 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28546416/recognising-paediatric-obstructive-sleep-apnoea-in-primary-care-diagnosis-and-management
#4
Rebecca Harrison, Rachel Edmiston, Caroline Mitchell
No abstract text is available yet for this article.
June 2017: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/28544189/year-in-review-2016-interstitial-lung-disease-pulmonary-vascular-disease-pulmonary-function-paediatric-lung-disease-cystic-fibrosis-and-sleep
#5
REVIEW
Adelle S Jee, Tamera J Corte, Stephen J Wort, Neil D Eves, Claire E Wainwright, Amanda Piper
No abstract text is available yet for this article.
May 25, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28504184/lessons-from-healthcare-utilization-in-children-with-obstructive-sleep-apnoea-syndrome
#6
Paz Martinez-Beneyto, Cristina E Soria Checa, Paloma Botella-Rocamora, Inés Rincon-Piedrahita, Francisco J Garcia Callejo, Jaime Marco Algarra
INTRODUCTION AND OBJECTIVES: Paediatric Obstructive Sleep Apnoea-Hypopnoea Syndrome (OSAS) is a multisystemic condition affecting child's health status that may be investigated analyzing demand for healthcare. OBJECTIVE: to quantify the frequency of medical consultations in children with OSAS over a 5-year period, compared to a healthy population. METHODS: A longitudinal, case-control, ambispective study was conducted at a hospital pertaining to the national public health system...
May 12, 2017: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/28472332/the-spectrum-of-rem-sleep-related-episodes-in-children-with-type-1-narcolepsy
#7
Elena Antelmi, Fabio Pizza, Stefano Vandi, Giulia Neccia, Raffaele Ferri, Oliviero Bruni, Marco Filardi, Gaetano Cantalupo, Rocco Liguori, Giuseppe Plazzi
Type 1 narcolepsy is a central hypersomnia due to the loss of hypocretin-producing neurons and characterized by cataplexy, excessive daytime sleepiness, sleep paralysis, hypnagogic hallucinations and disturbed nocturnal sleep. In children, close to the disease onset, type 1 narcolepsy has peculiar clinical features with severe cataplexy and a complex admixture of movement disorders occurring while awake. Motor dyscontrol during sleep has never been systematically investigated. Suspecting that abnormal motor control might affect also sleep, we systematically analysed motor events recorded by means of video polysomnography in 40 children with type 1 narcolepsy (20 females; mean age 11...
June 1, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28448761/sleeping-cupid-by-caravaggio-what-diagnosis
#8
Paolo Pozzilli, Marco Cappa
The Sleeping Cupid, by Italian painter Caravaggio is a masterpiece painted in 1608. Signs of an endocrine disease are hidden among the shadows of the painting. We decided to conduct a survey among endocrinologists practicing in Italy and asked them if they could identify a specific disease condition in Caravaggio's Sleeping Cupid. A total of 86 members from two Italian endocrine societies completed the survey, 67 from the Society of Endocrinology and 19 from the Society of Paediatric Endocrinology and Diabetology...
April 27, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28418336/intracranial-lesions-in-children-and-adolescents-with-morbid-obesity
#9
Ayça Törel Ergür, Sevinç Odabaşı Güneş, Sinan Tan, Ü Ayşe Tandırcıoğlu
BACKGROUND: Intracranial lesions may affect the hypothalamo-hypophyseal axis and lead to some neuro-endocrinological dysfunctions (hyperphagia, sleep disorders and hormonal dysfunctions). There is a very limited number of studies about childhood obesity and intracranial lesions. AIMS: To evaluate the incidence of intracranial lesions and its role in clinical symptoms and aetiology in cases with morbid obesity who have been admitted to the paediatric endocrinology department with this complaint...
April 5, 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/28418014/the-relationship-between-allergic-status-and-adenotonsillar-regrowth-a-retrospective-research-on-children-after-adenotonsillectomy
#10
Zirong Huo, Jun Shi, Yilai Shu, Mingliang Xiang, Jingrong Lu, Hao Wu
Adenotonsillar regrowth in children after adenotonsillectomy (T&A) for obstructive sleep apnea (OSA) is often seen in clinical treatment, however, the relationship between allergic disease and adenotonsillar regrowth remains unclear. In this retrospective study, children were assigned to either the recurrence or control group, and subdivided by age at operation. Among children over 36 months, those in the recurrence group had more allergic disease and higher IgE, IL-4, and IL-5 levels than the same-aged children in control group...
April 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28408467/isolated-mild-sleep-associated-hypoventilation-in-children-with-down-syndrome
#11
Wai Wong, Dennis Rosen
INTRODUCTION: Children with Down syndrome (DS) have a high incidence of obstructive sleep apnea (OSA) that is often associated with hypoventilation. Little is known, however, about the prevalence of sleep-associated hypoventilation independent of OSA in these children. METHODS: Retrospective chart review of all children with DS under 18 years of age undergoing polysomnography at a tertiary care paediatric hospital during a 2-year period. Exclusion criteria were as follow: those requiring oxygen or positive-pressure ventilation; with tracheostomy, baseline hypoxia, unrepaired cyanotic heart disease, pulmonary hypertension, and cerebral palsy; or OSA with >5 obstructions/hour...
April 13, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28391425/safety-tolerability-and-efficacy-of-drugs-for-treating-behavioural-insomnia-in-children-with-attention-deficit-hyperactivity-disorder-a-systematic-review-with-methodological-quality-assessment
#12
REVIEW
Shweta Anand, Henry Tong, Frank M C Besag, Esther W Chan, Samuele Cortese, Ian C K Wong
OBJECTIVE: A large proportion of paediatric patients with attention-deficit/hyperactivity disorder (ADHD) have associated sleep problems which not only affect the child's wellbeing but also impact family functioning. Management of sleep problems is consequently an important aspect of overall ADHD management in paediatric patients. Although some drugs are being used off-label for the management of paediatric insomnia, there is scant clinical evidence supporting their use. Our aim was to identify and assess the quality of published studies reporting the safety, tolerability and efficacy of drugs used for treating behavioural insomnia in children with ADHD...
June 2017: Paediatric Drugs
https://www.readbyqxmd.com/read/28390609/peri-operative-management-of-high-risk-paediatric-adenotonsillectomy-patients-a-survey-of-35-uk-tertiary-referral-centres
#13
Ryan Chin Taw Cheong, Philippe Bowles, Andrew Moore, Simon Watts
INTRODUCTION: Peri-operative management of high-risk paediatric patients undergoing adenotonsillectomy for treatment of obstructive sleep apnoea varies between tertiary referral hospitals. 'Day of surgery cancellation' (DoSC) rates of up to 11% have been reported due to pre-booked critical care being unavailable on the day of surgery as a result of competing needs from other hospital departments. We report the results of a survey of peri-operative management in UK tertiary care centres of high-risk paediatric patients undergoing adenotonsillectomy for obstructive sleep apnoea (OSA)...
May 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28377393/does-a-brief-behavioural-intervention-delivered-by-paediatricians-or-psychologists-improve-sleep-problems-for-children-with-adhd-protocol-for-a-cluster-randomised-translational-trial
#14
E Sciberras, M Mulraney, H Heussler, N Rinehart, T Schuster, L Gold, N Hayes, H Hiscock
INTRODUCTION: Up to 70% of children with attention-deficit/hyperactivity disorder (ADHD) experience sleep problems. We have demonstrated the efficacy of a brief behavioural intervention for children with ADHD in a large randomised controlled trial (RCT) and now aim to examine whether this intervention is effective in real-life clinical settings when delivered by paediatricians or psychologists. We will also assess the cost-effectiveness of the intervention. METHODS AND ANALYSIS: Children aged 5-12 years with ADHD (n=320) are being recruited for this translational cluster RCT through paediatrician practices in Victoria and Queensland, Australia...
April 4, 2017: BMJ Open
https://www.readbyqxmd.com/read/28366681/obstructive-sleep-apnoea-and-the-role-of-tongue-reduction-surgery-in-children-with-beckwith-wiedemann-syndrome
#15
REVIEW
Christopher M Cielo, Kelly A Duffy, Aesha Vyas, Jesse A Taylor, Jennifer M Kalish
Beckwith-Wiedemann syndrome (BWS) is a rare paediatric overgrowth disorder. Associated macroglossia is a feature of many children with BWS and is felt to be a risk factor for obstructive sleep apnoea (OSA). Sleep-disordered breathing is highly variable in this population. The relationship between degree of macroglossia or other genotypic or phenotypic factors and OSA severity has not been established. The natural history of OSA in this population is unknown; a variety of conservative and surgical therapies have been used to treat OSA in children with BWS but none have been studied systematically...
February 24, 2017: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/28366348/quality-of-life-and-excessive-daytime-sleepiness-in-children-and-adolescents-with-myotonic-dystrophy-type-1
#16
Genevieve Ho, John Widger, Michael Cardamone, Michelle A Farrar
OBJECTIVES: Myotonic dystrophy type 1 (DM1) is an autosomal dominant neuromuscular disease with variable severity that affects all ages. Sleepiness is an important co-morbidity affecting a large proportion of paediatric DM1 patients. The current study examined the relationship between sleepiness and quality of life in a paediatric DM1 cohort. METHODS: A cross-sectional study was conducted in children and adolescents with DM1 attending a multi-disciplinary neuromuscular clinic in a tertiary paediatric centre...
April 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28320073/a-model-linking-video-gaming-sleep-quality-sweet-drinks-consumption-and-obesity-among-children-and-youth
#17
O Turel, A Romashkin, K M Morrison
There is a growing need to curb paediatric obesity. The aim of this study is to untangle associations between video-game-use attributes and obesity as a first step towards identifying and examining possible interventions. Cross-sectional time-lagged cohort study was employed using parent-child surveys (t1) and objective physical activity and physiological measures (t2) from 125 children/adolescents (mean age = 13.06, 9-17-year-olds) who play video games, recruited from two clinics at a Canadian academic children's hospital...
March 20, 2017: Clinical Obesity
https://www.readbyqxmd.com/read/28289832/indirect-costs-related-to-caregivers-absence-from-work-after-paediatric-tonsil-surgery
#18
Gunnhildur Gudnadottir, G Ragnarson Tennvall, J Stalfors, J Hellgren
Tonsillotomy has gradually replaced tonsillectomy as the surgical method of choice in children with upper airway obstruction during sleep, because of less postoperative pain and a shorter recovery time. The aim of this study was to examine the costs related to caregivers' absenteeism from work after tonsillectomy (TE) and tonsillotomy (TT). All tonsillectomies and tonsillotomies in Sweden due to upper airway obstruction during 1 year, reported to the National Tonsil Surgery Register in children aged 1-11 were included, n = 4534...
June 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28274038/comparative-assessment-of-oral-health-related-quality-of-life-of-children-before-and-after-full-mouth-rehabilitation-under-general-anaesthesia-and-local-anaesthesia
#19
Jaai Vinod Rane, Jasmin Winnier, Rupinder Bhatia
INTRODUCTION: Early Childhood Caries (ECC) is an aggressive form of caries in a child who is 71 months of age or younger. If the child is cooperative, the treatment may be completed under Local Anaesthesia (LA). General Anaesthesia (GA) is considered if the child is uncooperative, medically compromised or if the parents are unable to return for regular visits and requests treatment under GA. Improved Oral health Related Quality of Life (OHRQoL) has been reported after dental treatment under GA...
January 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28267299/predicting-the-effect-of-treatment-in-paediatric-osa-by-clinical-examination-and-functional-respiratory-imaging
#20
Monique Slaats, Wim Vos, Cedric Van Holsbeke, Jan De Backer, Dieter Loterman, Wilfried De Backer, An Boudewyns, Stijn Verhulst
OBJECTIVE: The aim of this study was to investigate whether functional respiratory imaging (FRI) or clinical examination could predict treatment outcome for obstructive sleep apnea (OSA) in normal-weight, non-syndromic children. METHODS: Normal weight children diagnosed with OSA by polysomnography were prospectively included. All children got a thorough evaluation and an ultra-low dose computed tomography scan of the upper airway (UA). A 3-D reconstruction was built combined with computational fluid dynamics for FRI...
March 7, 2017: Pediatric Pulmonology
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