Masaaki Ito, Takaki Hiwasa, Yoko Oshima, Satoshi Yajima, Takashi Suzuki, Tatsuki Nanami, Makoto Sumazaki, Fumiaki Shiratori, Kimihiko Funahashi, Shu-Yang Li, Yasuo Iwadate, Hiroki Yamagata, Byambasteren Jambaljav, Minoru Takemoto, Koutaro Yokote, Hirotaka Takizawa, Hideaki Shimada
BACKGROUND: Esophageal cancer often appears as postoperative metastasis or recurrence after radical surgery. Although we had previously reported that serum programmed cell death ligand 1 (PD-L1) level correlated with the prognosis of esophageal cancer, further novel biomarkers are required for more precise prediction of the prognosis. Proprotein convertase subtilisin/kexin type 9 (PCSK9) is associated with the cholesterol metabolism. But there was no report of relationship between serum PCSK9 antibody and cancer...
2021: Frontiers in Oncology