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Dental enamel hypoplasia

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https://www.readbyqxmd.com/read/28625342/dental-investigation-of-mummies-from-the-capuchin-catacombs-of-palermo-circa-18th-19th-century-ce
#1
R Seiler, D Piombino-Mascali, F Rühli
Within the framework of the Sicily Mummy Project, the orofacial complex of a significant sample of individuals (n=111) from the Capuchin Catacombs of Palermo, Italy, was inspected. The heads and dentitions of the mummies were documented and the recorded findings described: the state of preservation of skeletal and soft tissues; dental pathologies such as carious lesions and alveolar bone loss; enamel hypoplasia; and ante- and post-mortem tooth loss. Despite limitations in data collection, the oral health of these mummies was assessed and the frequencies of pathologies were compared to those of similar populations...
May 31, 2017: Homo: Internationale Zeitschrift Für die Vergleichende Forschung Am Menschen
https://www.readbyqxmd.com/read/28608052/craniofacial-and-dental-characteristics-of-patients-with-vitamin-d-dependent-rickets-type-1a-compared-to-controls-and-patients-with-x-linked-hypophosphatemia
#2
Hans Gjørup, Signe Sparre Beck-Nielsen, Dorte Haubek
ᅟOBJECTIVES: Vitamin-D-dependent rickets type 1A (VDDR1A) is a rare inherited disease caused by defective activation of vitamin D. The aim of the study was to describe the craniofacial characteristics and the dental phenotype of patients with genetically confirmed VDDR1A. The VDDR1A findings were compared to findings in patients with X-linked hypophosphatemia (XLH) and healthy controls. MATERIAL AND METHODS: Ten patients with VDDR1A were identified. The reference group for the comparison of cephalometric findings was 49 adults without chronic disease...
June 12, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28605602/role-of-primary-cilia-in-odontogenesis
#3
M Hampl, P Cela, H L Szabo-Rogers, M Kunova Bosakova, H Dosedelova, P Krejci, M Buchtova
Primary cilium is a solitary organelle that emanates from the surface of most postmitotic mammalian cells and serves as a sensory organelle, transmitting the mechanical and chemical cues to the cell. Primary cilia are key coordinators of various signaling pathways during development and maintenance of tissue homeostasis. The emerging evidence implicates primary cilia function in tooth development. Primary cilia are located in the dental epithelium and mesenchyme at early stages of tooth development and later during cell differentiation and production of hard tissues...
June 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28566878/consequences-of-facial-hemangioma-with-regard-to-dental-treatment
#4
Gabriela Cristina Santin, Késsia Suênia Fidelis de Mesquita Guimarães, Sara Silva de Oliveira, Raquel Assed Bezerra da Silva, Paulo Nelson-Filho, Regina Guenka Palma-Dibb, Alexandra Mussolino de Queiroz
Hemangioma is a benign vascular tumor that affects 3%-10% of the population and usually does not require specific treatment due to spontaneous regression. The purpose of this paper is to present a case report of a child having been born prematurely and diagnosed with hemangioma in the head and neck, emphasizing the dentofacial changes and treatment used to provide care. Severe fibrous scars were found in the perioral region and below the ear that limited the patient's ability to open her mouth. The child exhibited anterior open bite as well as dental caries in the lower jaw, hypomineralization, and enamel hypoplasia...
January 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/28518210/regular-graveyard-in-the-stronghold-versus-settlement-burials-in-the-bailey-comparison-of-early-medieval-populations-from-pohansko-czech-republic
#5
Kateřina Kalová, Renáta Přichystalová, Kateřina Boberová, Alena Pavlůsková
The aim of the study is to identify possible differences in the prevalence of biological stress markers (cribra orbitalia, linear enammel hypoplasia), dental caries, activity markers (Schmorl's nodes) and markers of violence (traumatic lesions) in populations from a typical graveyard around the first church (9(th)-10(th) century AD) in the stronghold and from settlement burials in the southern bailey (second half of the 9(th) - beginning of the 10(th) century AD) of Slavs from Pohansko (Czech Republic). Cribra orbitalia and enamel hypoplasia did not markedly differ in either population...
May 15, 2017: Anthropologischer Anzeiger; Bericht über die Biologisch-anthropologische Literatur
https://www.readbyqxmd.com/read/28494608/parenteral-nutrition-in-childhood-and-consequences-for-dentition-and-gingivae
#6
D Olczak-Kowalczyk, M Danko, E Banaś, D Gozdowski, K Popińska, E Krasuska-Sławińska, J Książyk
AIM: Assessment of dentition in children under parenteral nutrition, risk factors for caries, and dental developmental abnormalities. MATERIALS AND METHODS: The study involved 63 patients (aged 2.25-16.6 years), i.e. 32 subjects receiving parenteral nutrition for a mean period of 5.6±2.94 years, and 31 healthy control subjects. Oral hygiene (OHI-S, PL-I), gingival (GI), and dentition status (caries, DMFT/dmft, enamel defects, shape alterations), frequency of oral meals and frequency of cariogenic snacks consumption were evaluated...
March 2017: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28489513/thyroid-function-during-early-life-and-dental-development
#7
S Vucic, T I M Korevaar, B Dhamo, V W V Jaddoe, R P Peeters, E B Wolvius, E M Ongkosuwito
Children with low levels of thyroid hormones (hypothyroidism) have delayed tooth eruption, enamel hypoplasia, micrognathia, and anterior open bite, whereas children with hyperthyroidism may suffer from accelerated tooth eruption, maxillary, and mandibular osteoporosis. However, it is still unknown whether thyroid function variations within the normal or subclinical range also have an impact on hard dental tissues in healthy children. The objective of this study was, therefore, to investigate the association between thyroid function from the fetal period until early childhood and dental development at school age...
May 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28475088/rare-sequelae-in-the-permanent-successor-due-to-trauma-in-the-primary-incisor-a-case-report
#8
Juliana Sayuri Kimura, Isabela Capparelli Cadioli, Daniela Mazzotti Bressan Alves, Cássio José Fornazari Alencar, Ricardo De Nardi Fonoff, Marcia Turolla Wanderley
Severe dental trauma-such as intrusion or avulsion-to the primary dentition in infants and toddlers may cause developmental disturbances in the permanent successor. In this case, a 9-year-old boy was referred for treatment due to the absence of his permanent maxillary right central incisor. The mother reported avulsion of the corresponding primary tooth when the patient was 2 years old. The radiographic examination revealed impaction and root dilaceration of the permanent tooth; therefore, the treatment plan was tooth extraction...
May 2017: General Dentistry
https://www.readbyqxmd.com/read/28407772/the-end-of-a-dogma-the-safety-of-doxycycline-use-in-young-children-for-malaria-treatment
#9
REVIEW
Tiphaine Gaillard, Sébastien Briolant, Marylin Madamet, Bruno Pradines
Anti-malarial drug resistance to chloroquine and sulfadoxine-pyrimethamine has spread from Southeast Asia to Africa. Furthermore, the recent emergence of resistance to artemisinin-based combination therapy (ACT) in Southeast Asia highlights the need to identify new anti-malarial drugs. Doxycycline is recommended for malaria chemoprophylaxis for travel in endemic areas, or in combination with the use of quinine for malaria treatment when ACT is unavailable or when the treatment of severe malaria with artesunate fails...
April 13, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28407333/bioarchaeological-profile-of-stress-and-dental-disease-among-ancient-high-altitude-himalayan-communities-of-nepal
#10
Jacqueline T Eng, Mark Aldenderfer
OBJECTIVES: This study examines biological indicators of dental disease and nonspecific stress in human remains of three high altitude Himalayan archaeological sites to test whether shared ecological constraints led to similar bioarchaeological profiles in these markers. METHODS: Samples (n = 170) derive from three sites in Nepal dating to two periods (400-50 BCE and c. 400-650 CE). Dental diseases (caries, antemortem tooth loss, and abscesses) were assessed by both the number of individuals and the number of elements observed, while childhood stress markers included observation of growth disruptions (enamel hypoplasia and adult femur length/stature) and cranial porosities...
April 13, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/28382465/significance-of-genetic-variations-in-developmental-enamel-defects-of-primary-dentition-in-polish-children
#11
Karolina Gerreth, Katarzyna Zaorska, Maciej Zabel, Michal Nowicki, Maria Borysewicz-Lewicka
OBJECTIVES: The aim of the study was to reveal the association between developmental defects of enamel (DDE) and single nucleotide polymorphisms (SNPs) in the ENAM, AMELX, AMBN, TUFT1, and TFIP11 genes. MATERIAL AND METHODS: The molecular analysis was carried out in 52 children, aged 10-42 months, from four nursery schools situated in the region of Poznan, Poland (26 individuals with hypomineralization and/or hypoplasia of enamel - "cases" and 26 unaffected children - "controls"), chosen from 262 individuals that had prior dental examination...
April 5, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28347809/developmental-defects-of-enamel-and-dental-caries-in-the-primary-dentition-a-systematic-review-and-meta-analysis
#12
REVIEW
Francine S Costa, Ethieli R Silveira, Gabriela S Pinto, Gustavo G Nascimento, William Murray Thomson, Flávio F Demarco
OBJECTIVES: This systematic review and meta-analysis evaluated the association between developmental defects of enamel and dental caries in the primary dentition. SOURCES: Electronic searches were performed in PubMed, Web of Knowledge, Scopus and Scielo for the identification of relevant studies. STUDY SELECTION: Observational studies that examined the association between developmental defects of enamel and dental caries in the deciduous dentition were included...
May 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28258662/a-novel-gja1-mutation-in-oculodentodigital-dysplasia-with-extensive-loss-of-enamel
#13
T Porntaveetus, C Srichomthong, A Ohazama, K Suphapeetiporn, V Shotelersuk
OBJECTIVE: To characterize clinical features and identify genetic causes of a patient with oculodentodigital dysplasia (ODDD). SUBJECTS AND METHODS: Clinical, dental, radiological features were obtained. DNA was collected from an affected Thai family. Whole-exome sequencing was employed to identify the disease-causing mutation causing ODDD. The presence of the identified variant was confirmed by Sanger sequencing. RESULTS: The proband suffered with extensive enamel hypoplasia, polysyndactyly and clinodactyly of the 3rd-5th fingers, microphthalmia, and unique facial characteristics of ODDD...
March 4, 2017: Oral Diseases
https://www.readbyqxmd.com/read/28251719/high-altitude-agriculture-in-the-titicaca-basin-800-bce-200-ce-impacts-on-nutrition-and-disease-load
#14
Sara L Juengst, Dale L Hutchinson, Sergio J Chávez
OBJECTIVES: This study investigates the biological impacts of sedentism and agriculture on humans living in the high altitude landscape of the Titicaca Basin between 800 BCE and CE 200. The transition to agriculture in other global areas resulted in increases in disease and malnutrition; the high altitude of the Titicaca Basin could have exacerbated this. Our objective is to test whether the high altitude of the Titicaca Basin created a marginal environment for early agriculturalists living there, reflected through elevated rates of malnutrition and/or disease...
March 2, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/28243307/a-case-report-of-dilacerated-crown-of-a-permanent-mandibular-central-incisor
#15
Behnam Bolhari, Salma Pirmoazen, Ensieh Taftian, Somayeh Dehghan
Trauma to primary teeth can lead to devastating sequels in development of permanent successors. The disturbance may range from enamel hypoplasia and/or hypo-calcification to arrest of dental bud development. Crown dilaceration of permanent teeth is one of the consequences of trauma to deciduous teeth mainly due to intrusion or avulsion. This report presents a mandibular central incisor with dilacerated crown and yellowish discoloration with symptomatic apical abscess. History revealed avulsion of primary mandibular central incisors...
November 2016: Journal of Dentistry of Tehran University of Medical Sciences
https://www.readbyqxmd.com/read/28211566/applying-standard-perikymata-profiles-to-pongo-pygmaeus-canines-to-estimate-perikymata-counts-between-linear-enamel-hypoplasias
#16
Mackie O'Hara
OBJECTIVES: Recently, studies have interpreted regular spacing and average number of perikymata between dental enamel defects in orangutans to reflect seasonal episodes of physiological stress. To estimate the amount of time between developmental defects (enamel hypoplasia), studies have relied on perikymata counts. Unfortunately, perikymata are frequently not continuously visible between defects, significantly reducing data sets. A method is presented here for estimating the number of perikymata between defects using standard perikymata profiles (SPP) that allow the number of perikymata between all pairs of defects across a tooth to be analyzed...
May 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28194533/the-diagnostic-accuracy-of-a-laser-fluorescence-device-and-digital-radiography-in-detecting-approximal-caries-lesions-in-posterior-permanent-teeth-an-in-vivo-study
#17
R Menem, I Barngkgei, N Beiruti, I Al Haffar, Easter Joury
The aim of this in vivo study was to test the diagnostic accuracy of a pen-type laser fluorescence (LFpen) device in detecting approximal caries lesions, in posterior permanent teeth, at the cavitation and non-cavitation thresholds, and compare it with that of digital bitewing radiography. Thirty patients (aged 18-37), who attended the Faculty of Dentistry at Damascus University for a dental examination, were consecutively screened. Ninety approximal surfaces of posterior permanent teeth without frank cavitations, enamel hypoplasia or restorations were selected and examined using the LFpen (DIAGNOdent pen) and digital bitewing radiography...
April 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28191355/morquio-s-syndrome-a-case-report-of-two-siblings
#18
Sathish Muthukumar Ramalingam, Daya Srinivasan, Sandhya ArunKumar, Joe Louis ChiriyanKandath, Sriram Kaliamoorthy
Morquio syndrome or MPS IVA is a rare type of lysosomal storage disease associated with highly specific dental abnormalities. We present two siblings with enamel hypoplasia and skeletal abnormalities. A diagnosis of mucopolysaccharidosis type IVA was reached based on the clinical, radiographic, and dental findings of the patients. The dental findings are useful diagnostic aid for the early diagnosis of this debilitating disorder.
2017: Case Reports in Dentistry
https://www.readbyqxmd.com/read/28095448/distribution-of-cathepsin-k-in-late-stage-of-tooth-germ-development-and-its-function-in-degrading-enamel-matrix-proteins-in-mouse
#19
Tao Jiang, Fen Liu, Wei-Guang Wang, Xin Jiang, Xuan Wen, Kai-Jin Hu, Yang Xue
Cathepsin K (CTSK) is a member of cysteine proteinase family, and is predominantly expressed in osteoclastsfor degradationof bone matrix proteins. Given the similarity in physical properties of bone and dental mineralized tissues, including enamel, dentin and cementum, CTSK is likely to take part in mineralization process during odontogenesis. On the other hand, patients with pycnodysostosis caused by mutations of the CTSK gene displayedmultipledental abnormalities, such as hypoplasia of the enamel, obliterated pulp chambers, hypercementosis and periodontal disease...
2017: PloS One
https://www.readbyqxmd.com/read/28081373/loss-of-function-of-evc2-in-dental-mesenchyme-leads-to-hypomorphic-enamel
#20
H Zhang, H Takeda, T Tsuji, N Kamiya, T Kunieda, Y Mochida, Y Mishina
Ellis-van Creveld (EvC) syndrome is an autosomal-recessive skeletal dysplasia, characterized by short stature and postaxial polydactyly. A series of dental abnormalities, including hypomorphic enamel formation, has been reported in patients with EvC. Despite previous studies that attempted to uncover the mechanism leading to abnormal tooth development, little is known regarding how hypomorphic enamel is formed in patients with EvC. In the current study, using Evc2/ Limbin mutant mice we recently generated, we analyzed enamel formation in the mouse incisor...
April 2017: Journal of Dental Research
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