Paul Govaert, Maarten Lequin, Renate Swarte, Simon Robben, René De Coo, Nynke Weisglas-Kuperus, Yolanda De Rijke, Maarten Sinaasappel, James Barkovich
OBJECTIVE: We report serial magnetic resonance (MR) and sonographic behavior of globus pallidus in 5 preterm and 3 term infants with kernicterus and describe the clinical context in very low birth weight preterm infants. On the basis of this information, we suggest means of diagnosis and prevention. METHODS: Charts and MR and ultrasound images of 5 preterm infants and 3 term infants with suspected bilirubin-associated brain damage were reviewed. Included were preterm infants with severe hearing loss, quadriplegic hypertonia, and abnormal hypersignal of globus pallidus on T2-weighted MR imaging (MRI)...
December 2003: Pediatrics