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https://www.readbyqxmd.com/read/28103651/addressing-the-challenges-in-forensic-drug-chemistry
#1
EDITORIAL
Simon D Brandt, Pierce V Kavanagh
No abstract text is available yet for this article.
January 19, 2017: Drug Testing and Analysis
https://www.readbyqxmd.com/read/28102586/creatinine-in-urine-a-method-comparison
#2
Marc Luginbühl, Wolfgang Weinmann
Drug screening in urine is widely applied in forensic toxicology. Contrary to blood analysis, excessive or reduced fluid intake can substantially alter the concentration of substances in urine. As a standard to detect urinary dilution, creatinine concentrations are analyzed. A sample with a concentration below 20 mg/dL is generally defined as too diluted to provide a valid result in abstinence control samples. This work investigates the potential of three different methods for the determination of creatinine concentrations in urine samples: A ZIC-HILIC based LC-MS/MS method, a spectrophotometric method on an AU 480 chemistry system, and a portable, immunoassay based point-of-care testing device was compared by measuring 200 urine samples...
January 19, 2017: Drug Testing and Analysis
https://www.readbyqxmd.com/read/28102433/advanced-forensic-validation-for-human-spermatozoa-identification-using-sperm-hy-liter%C3%A2-express-with-quantitative-image-analysis
#3
Ayari Takamura, Ken Watanabe, Tomoko Akutsu
Identification of human semen is indispensable for the investigation of sexual assaults. Fluorescence staining methods using commercial kits, such as the series of SPERM HY-LITER™ kits, have been useful to detect human sperm via strong fluorescence. These kits have been examined from various forensic aspects. However, because of a lack of evaluation methods, these studies did not provide objective, or quantitative, descriptions of the results nor clear criteria for the decisions reached. In addition, the variety of validations was considerably limited...
January 19, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28101751/fatal-disseminated-neonatal-herpes-simplex-virus-type-1-infection-in-neonates-in-a-forensic-setting
#4
Jia Hao Wu, Sarah Parsons
No abstract text is available yet for this article.
January 19, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28101645/forensic-parameters-of-19-x-str-polymorphisms-in-two-chinese-populations
#5
Chuncao Deng, Feng Song, Jienan Li, Yi Ye, Lushun Zhang, Weibo Liang, Haibo Luo, Yingbi Li
Application of X-STRs as complements of autosomal STR application in the forensic genetics has become a tendency for kinship testing, especially in deficiency paternity cases. Recently, a novel kit of 19 X-STR loci was developed, which permitted the analysis of 19 STR in the same PCR reaction, and these markers can be clustered into seven groups for the physical linkage. The objective of this study was to evaluate the allele and haplotype diversity of 19 X-STR loci in the Uygur (n = 220) and Tibetan nationality (n = 270) and to estimate the usefulness for complex kinship analysis...
January 18, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28098920/-too-long-in-tbs-a-study-on-patients-receiving-forensic-psychiatric-tbs-treatment-for-15-years-or-longer
#6
H Nijman, S Lammers, M Vrinten, E Bulten
In 2013 in the Netherlands about 100 forensic psychiatric patients were treated in tbs-hospitals for 15 years or more.<br/> AIM: To investigate the variables that characterise patients who have been receiving forensic psychiatric treatment (tbs) for 15 years or more, and to obtain insight in which actions might be helpful to facilitate discharge or transfer of such patients to other (mental health care) facilities, according to their caregivers and experts.<br/> METHOD: The group of long-term tbs-patients (n = 97) was compared with regard to diagnostic characteristics, 'basic historical risks' (as assessed by risk assessment instruments), and behaviour  to three other groups of forensic patients: a...
2017: Tijdschrift Voor Psychiatrie
https://www.readbyqxmd.com/read/28097647/microbiota-composition-and-pulmonary-surfactant-protein-expression-as-markers-of-death-by-drowning
#7
So-Yeon Lee, Seung-Kyun Woo, So-Min Lee, Eun-Ju Ha, Kyoung-Hee Lim, Kyung-Hwa Choi, Young-Hee Roh, Yong-Bin Eom
Pathological diagnosis of drowning remains a challenge for forensic science, because of a lack of pathognomonic findings. We analyzed microbiota and surfactant protein in the lungs for a novel diagnosis of drowning. All rats were divided into drowning, postmortem submersion, and control groups. The water, lungs, closed organs (kidney and liver), and cardiac blood in rats were assayed by targeting 16S ribosomal RNA of Miseq sequencing. Lung samples were analyzed by immunohistochemical staining for surfactant protein A...
January 18, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28096870/the-economic-crisis-in-greece-and-its-impact-on-the-seasonality-of-suicides-in-the-athens-greater-area
#8
Christos Christodoulou, Vasiliki Efstathiou, Ioannis Michopoulos, Maria Gkerekou, Antonios Paraschakis, Filippos Koutsaftis, Athanassios Douzenis
OBJECTIVE: The economic crisis and the implementation of austerity measures in Greece lead to significant socioeconomic changes. The effects of the crisis were mainly felt by the Greek population during the years 2011 and 2012. This study aimed to investigate the impact of Greece's economic crisis on the seasonality of suicides in the Athens Greater Area. METHODS: Data were collected for all recorded cases of suicides committed over a 5-year period (from 2008 to 2012) from the Athens Department of Forensic Medicine...
January 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/28096105/the-value-of-paediatric-assessment-in-historic-child-sexual-abuse
#9
Sarah Al-Jilaihawi, Kevin Borg, Sabine Maguire, Deborah Hodes
INTRODUCTION: A perception exists that there are few benefits of a paediatric assessment in historic child sexual abuse (CSA), as the likelihood of finding forensic evidence is low. AIM: To determine the value of a comprehensive paediatric assessment in a dedicated clinic for children and young people who present following suspicion or allegation of historic CSA. METHOD: All children with suspected or alleged historic CSA, defined as >7 days after the last episode of sexual assault in pubertal girls, or >3 days for prepubertal girls and all boys, were assessed in a specialised paediatric clinic...
January 17, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28095806/predictors-of-mental-health-review-tribunal-mhrt-outcome-in-a-forensic-inpatient-population-a-prospective-cohort-study
#10
Amelia Jewell, Kimberlie Dean, Tom Fahy, Alexis E Cullen
BACKGROUND: Previous studies have investigated factors associated with outcome at Mental Health Review Tribunals (MHRTs) in forensic psychiatric patients; however, dynamic variables such as treatment compliance and substance misuse have scarcely been examined, particularly in UK samples. We aimed to determine whether dynamic factors related to behaviour, cooperation with treatment, and activities on the ward were prospectively associated with outcome at MHRT. METHODS: At baseline, demographic, clinical, behavioural, and treatment-related factors were ascertained via electronic medical records and census forms completed by the patient's clinical team...
January 17, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28095345/forensic-assignment-to-geographic-origin-a-useful-tool-in-seafood-fraud-control
#11
J L Horreo, G Machado-Schiaffino, E García-Vázquez
Seafood fraud is an economically motivated and widely spread problem encompassing drastic consequences in both public health and species conservation. In Northern Spain, only the first Atlantic salmon (Salmo salar) catch of the angling season (named Campanu) can be sold. In the year 2011, an angler denounced it on regional Court claiming that the Campanu (which was sold in 6000€) was fraudulent because it had been caught from another river than the fisherman ("the seller") stated. Here, we report the first judicial case of application of geographical genetic assignment in a fish species in Spain...
January 10, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28092535/super-resolution-person-re-identification-with-semi-coupled-low-rank-discriminant-dictionary-learning
#12
Xiao-Yuan Jing, Xiaoke Zhu, Fei Wu, Ruimin Hu, Xinge You, Yunhong Wang, Hui Feng, Jing-Yu Yang
Person re-identification has been widely studied due to its importance in surveillance and forensics applications. In practice, gallery images are high-resolution (HR) while probe images are usually low-resolution (LR) in the identification scenarios with large variation of illumination, weather or quality of cameras. Person re-identification in this kind of scenarios, which we call super-resolution (SR) person re-identification, has not been well studied. In this paper, we propose a semi-coupled low-rank discriminant dictionary learning (SLD2L) approach for SR person re-identification task...
January 10, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28091985/frequency-of-forensic-toxicological-analysis-in-external-cause-deaths-among-nursing-home-residents-an-analysis-of-trends
#13
Georgia Aitken, Briony Murphy, Jennifer Pilgrim, Lyndal Bugeja, David Ranson, Joseph Elias Ibrahim
There is a paucity of research examining the utility of forensic toxicology in the investigation of premature external cause deaths of residents in nursing homes. The aim of this study is to describe the frequency and characteristics of toxicological analysis conducted in external cause (injury-related) deaths amongst nursing home residents in Victoria, Australia. This study was a retrospective cohort study examining external cause deaths among nursing home residents during the period July 1, 2000 to December 31, 2012 in Victoria, Australia, using the National Coronial Information System (NCIS)...
January 16, 2017: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/28091758/-deaths-from-propofol-abuse-survey-of-institutes-of-forensic-medicine-in-germany-austria-and-switzerland
#14
C Maier, J Iwunna, M Tsokos, F Mußhoff
Previous references suggesting a high mortality of propofol addiction in medical personnel were mostly based on surveys of the heads of medical departments or case reports; therefore, a questionnaire was sent to 48 forensic medicine departments in Germany, Austria and Switzerland concerning the number of autopsies carried out between 2002-2112 on medical personnel with the suspicion of abuse of propofol or other analgesics. The response rate was 67%. In 16 out of the 32 responding departments 39 deaths (27 males) were observed with previous connections to anesthesiology, intensive care or emergency departments of which 22 were physicians, 13 nurses, 2 other personnel and 2 were unknown...
January 13, 2017: Der Anaesthesist
https://www.readbyqxmd.com/read/28091725/genetic-polymorphism-investigation-of-the-chinese-yi-minority-using-powerplex%C3%A2-y23-str-amplification-system
#15
GuangLin He, PengYu Chen, Xing Zou, Xu Chen, Feng Song, Jing Yan, YiPing Hou
Twenty-three Y-STR loci (DYS576, DYS389I, DYS389 II, DYS448, DYS19, DYS391, DYS481, DYS549, DYS533, DYS438, DYS437, DYS570, DYS635, DYS390, DYS439, DYS392, DYS393, DYS458 DYS456, DYS643, Y-GATA-H4, and DYS385a/b) included in the next-generation PowerPlex® Y23 System were first investigated in 311 unrelated, healthy male individuals from the Yi minority population residing in the Liangshan Yi Autonomous Prefecture, Sichuan, China. A total of 179 alleles and 297 haplotypes were discovered in the Yi group. In total, 285 haplotypes among them were unique, and the remaining 12 haplotypes were observed in two or three individuals...
January 16, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/28090491/allelic-variance-among-abo-blood-group-genotypes-in-a-population-from-the-western-region-of-saudi-arabia
#16
Abdularahman B O Mohamed, Salwa Ibrahim Hindawi, Sameer Al-Harthi, Qamre Alam, Mohammad Zubair Alam, Absarul Haque, Waseem Ahmad, Ghazi A Damanhouri
BACKGROUND: Characterization of the ABO blood group at the phenotype and genotype levels is clinically essential for transfusion, forensics, and population studies. This study elucidated ABO phenotypes and genotypes, and performed an evaluation of their distribution in individuals from the western region of Saudi Arabia. METHODS: One-hundred and seven samples underwent standard serological techniques for ABO blood group phenotype analysis. ABO alleles and genotypes were identified using multiplex polymerase chain reaction, and electrophoretic analysis was performed to evaluate the highly polymorphic ABO locus...
December 2016: Blood Research
https://www.readbyqxmd.com/read/28089301/time-since-discharge-of-9mm-cartridges-by-headspace-analysis-part-2-ageing-study-and-estimation-of-the-time-since-discharge-using-multivariate-regression
#17
M Gallidabino, F S Romolo, C Weyermann
Estimating the time since discharge of spent cartridges can be a valuable tool in the forensic investigation of firearm-related crimes. To reach this aim, it was previously proposed that the decrease of volatile organic compounds released during discharge is monitored over time using non-destructive headspace extraction techniques. While promising results were obtained for large-calibre cartridges (e.g., shotgun shells), handgun calibres yielded unsatisfying results. In addition to the natural complexity of the specimen itself, these can also be attributed to some selective choices in the methods development...
December 27, 2016: Forensic Science International
https://www.readbyqxmd.com/read/28089299/the-non-sense-of-routinely-analysing-beta-hydroxybutyric-acid-in-forensic-toxicology-casework
#18
Nele Sadones, Willy E Lambert, Christophe P Stove
Beta-hydroxybutyric acid (BHB) is a ketone body which is generated from fatty acids as an alternative energy source when glucose is not available. Determination of this compound may be relevant in the forensic laboratory as ketoacidosis - an elevated level of ketone bodies - may contribute to the cause of death. In this study, we aimed at determining the relevance of routinely implementing BHB analysis in the forensic toxicological laboratory, as BHB analysis typically requires an additional workload. We therefore performed an unbiased retrospective analysis of BHB in 599 cases, comprising 553 blood, 232 urine and 62 vitreous humour samples...
January 7, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28089298/gunshot-wound-trajectory-analysis-using-forensic-animation-to-establish-relative-positions-of-shooter-and-victim
#19
Aisling A Galligan, Craig Fries, Judy Melinek
Forensic pathologists who autopsy the victims of gun violence are often called upon to answer questions in both criminal and civil proceedings about the relative position of the shooter and the victim. In this case report of an officer-involved shooting incident, the statement of the police officer appeared to be in direct contradiction to the statements of other eyewitnesses, the evidence at the scene, and the final resting position of the decedent's body. Trajectory analysis of two gunshot wound pathways (only one of which was instantaneously incapacitating) was performed to assess the veracity of the officer's statement and forensic animation was used to create a court exhibit...
January 5, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28089297/time-since-discharge-of-9mm-cartridges-by-headspace-analysis-part-1-comprehensive-optimisation-and-validation-of-a-headspace-sorptive-extraction-hsse-method
#20
M Gallidabino, F S Romolo, C Weyermann
Estimating the time since discharge of spent cartridges can be a valuable tool in the forensic investigation of firearm-related crimes. To reach this aim, it was previously proposed that the decrease of volatile organic compounds released during discharge is monitored over time using non-destructive headspace extraction techniques. While promising results were obtained for large-calibre cartridges (e.g., shotgun shells), handgun calibres yielded unsatisfying results. In addition to the natural complexity of the specimen itself, these can also be attributed to some selective choices in the methods development...
December 24, 2016: Forensic Science International
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