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https://www.readbyqxmd.com/read/29151122/genetic-polymorphisms-in-18-autosomal-str-loci-in-the-tibetan-population-living-in-tibet-chamdo-southwest-china
#1
Zhenghui Li, Jian Zhang, Hantao Zhang, Ziqing Lin, Jian Ye
Short tandem repeats (STRs) play a vitally important role in forensics. Population data is needed to improve the field. There is currently no large population data-based data set in Chamdo Tibetan. In our study, the allele frequencies and forensic statistical parameters of 18 autosomal STR loci (D5S818, D21S11, D7S820, CSF1PO, D2S1338, D3S1358, VWA, D8S1179, D16S539, PentaE, TPOX, TH01, D19S433, D18S51, FGA, D6S1043, D13S317, and D12S391) included in the DNATyper™19 kit were investigated in 2249 healthy, unrelated Tibetan subjects living in Tibet Chamdo, Southwest China...
November 18, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/29151121/impact-of-several-wearers-on-the-persistence-of-dna-on-clothes-a-study-with-experimental-scenarios
#2
Micaela Poetsch, Manuel Pfeifer, Helen Konrad, Thomas Bajanowski, Janine Helmus
The detection of DNA of a certain person on the inside of a piece of clothing involved in a crime scene is usually seen as confirmation that this person is the owner or bearer and therefore participated in this crime. However, besides the possibilities of secondary or even tertiary transfer of DNA, the accused often argues that he lent the garment to another person who by chance did not leave any DNA while committing the crime. Then, forensic genetic scientists have to answer the question how long DNA persists on an item used in daily routine and how long a piece of clothing must be worn to definitively leave detectable DNA behind...
November 18, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/29151005/synthesis-of-a-novel-polymeric-magnetic-solid-phase-extraction-adsorbent-for-selective-extraction-of-amphetamine-from-urine-samples-coupled-with-high-performance-liquid-chromatography
#3
Arezou Taghvimi, Marjan Ghorbani, Hamed Hamishehkar
A novel pH-responsive block copolymer (Poly ethylene glycol-b-poly (N,N-dimethylaminoethylmethacrylate-co-maleic acid) was designed for the decoration and stabilization of magnetic nanoparticles (MNPs) to apply as an efficient magnetic nano adsorbent for extraction of amphetamine (AM) from biological urine samples to be determined by high performance liquid chromatography ultra violet detector (HPLC-UV). Full characterization of the synthesized Polymeric magnetic nanoparticles (PMNPs) were followed by various techniques like Fourier transform infrared (FT-IR) spectroscopy, powder x-ray diffraction (XRD), scanning electron microscopy (SEM), and vibrating sample magnetometer (VSM)...
November 18, 2017: Drug Testing and Analysis
https://www.readbyqxmd.com/read/29150717/genetic-diversity-and-phylogenetic-study-of-the-chinese-gelao-ethnic-minority-via-23-y-str-loci
#4
Pengyu Chen, Yanyan Han, Guanglin He, Haibo Luo, Tianzhen Gao, Feng Song, Dengfu Wan, Jian Yu, Yiping Hou
Haplotype diversity for 23 Y chromosomal short tandem repeat (Y-STR) loci included in the PowerPlex(®) Y23 System was analyzed in the Chinese Gelao minority group of 234 unrelated males living in Daozhen Gelao-Miao Autonomous County in Guizhou Province, southwest China. A total of 216 different haplotypes were detected, of which 199 haplotypes were unique. The overall haplotype diversity (HD) and discrimination capacity (DC) were 0.9996 and 0.9231, respectively. The gene diversity (GD) ranged from 0.4159 (DYS438) to 0...
November 17, 2017: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/29150183/genetic-analysis-of-29-y-str-loci-in-the-chinese-han-population-from-shanghai
#5
Yuxiang Zhou, Chengchen Shao, Liming Li, Yaqi Zhang, Baonian Liu, Qinrui Yang, Qiqun Tang, Shilin Li, Jianhui Xie
The analysis of Y chromosomal short tandem repeats (Y-STRs) provides important information that can be used to forensic investigation and population studies. In this study, typing of 29 Y-STRs included in the PowerPlex(®) Y23 system (PPY23) and Yfiler™ Plus system (Yfiler plus) was performed on 843 unrelated male samples from Han population in Shanghai. Besides null, duplicate, and intermediate alleles reported in previous studies, an allele of 10 at DYS643 with a 2-base deletion in the flanking region was initially observed...
November 11, 2017: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/29149686/preliminary-application-of-structure-from-motion-and-gis-to-document-decomposition-and-taphonomic-processes
#6
Connor D Carlton, Samantha Mitchell, Patrick Lewis
Over the past decade, Structure from Motion (SfM) has increasingly been used as a means of digital preservation and for documenting archaeological excavations, architecture, and cultural material. However, few studies have tapped the potential of using SfM to document and analyze taphonomic processes affecting burials for forensic sciences purposes. This project utilizes SfM models to elucidate specific post-depositional events that affected a series of three human cadavers deposited at the South East Texas Applied Forensic Science Facility (STAFS)...
November 2, 2017: Forensic Science International
https://www.readbyqxmd.com/read/29149652/estimation-of-stature-from-hand-and-handprint-measurements-in-iban-population-in-sarawak-malaysia-and-its-applications-in-forensic-investigation
#7
Nuranis-Raihan Zulkifly, Roswanira Abd Wahab, Elizabeth Layang, Dzulkiflee Ismail, Wan Nur Syuhaila Mat Desa, Salina Hisham, Naji A Mahat
Handprints and dismembered hands are commonly found during crime scene investigations and disaster victim identifications, respectively. It has been indicated that the accuracy of handprint and hand measurements for estimating stature maybe population specific. Since Iban is the largest ethnic population in Sarawak, Malaysia and because the application of anthropometry of hand and handprint within this population as well as other populations within the Southeast Asian countries remain unreported, this present study that investigated the reliability and accuracy of these two anthropometric aspects acquires forensic significance...
October 31, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29149651/anthropometric-measurements-in-iranian-men
#8
Jaber Gharehdaghi, Maryam Baazm, Masoud Ghadipasha, Sadra Solhi, Farhoud Toutounchian
There is inevitable need for data regarding anthropometric measurements of each community's population. These anthropometric data have various applications, including health assessment, industrial designing, plastic & orthopedic surgery, nutritional studies, anatomical studies and forensic medicine investigations. Anthropometric parameters vary from race to race throughout the world, hence providing an anthropometric profile model of residents of different geographic regions seems to be necessary. To our knowledge, there is no report of bone parameters of the Iranian population...
November 14, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/29149210/development-and-validation-of-open-source-software-for-dna-mixture-interpretation-based-on-a-quantitative-continuous-model
#9
Sho Manabe, Chie Morimoto, Yuya Hamano, Shuntaro Fujimoto, Keiji Tamaki
In criminal investigations, forensic scientists need to evaluate DNA mixtures. The estimation of the number of contributors and evaluation of the contribution of a person of interest (POI) from these samples are challenging. In this study, we developed a new open-source software "Kongoh" for interpreting DNA mixture based on a quantitative continuous model. The model uses quantitative information of peak heights in the DNA profile and considers the effect of artifacts and allelic drop-out. By using this software, the likelihoods of 1-4 persons' contributions are calculated, and the most optimal number of contributors is automatically determined; this differs from other open-source software...
2017: PloS One
https://www.readbyqxmd.com/read/29149052/flanking-variation-influences-rates-of-stutter-in-simple-repeats
#10
August E Woerner, Jonathan L King, Bruce Budowle
It has been posited that the longest uninterrupted stretch (LUS) of tandem repeats, as defined by the number of exactly matching repeating motif units, is a better predictor of rates of stutter than the parental allele length (PAL). While there are cases where this hypothesis is likely correct, such as the 9.3 allele in the TH01 locus, there can be situations where it may not apply as well. For example, the PAL may capture flanking indel variations while remaining insensitive to polymorphisms in the repeat, and these haplotypic changes may impact the stutter rate...
November 17, 2017: Genes
https://www.readbyqxmd.com/read/29146299/functional-connectivity-during-affective-mentalizing-in-criminal-offenders-with-psychotic-disorders-associations-with-clinical-symptoms
#11
Carla L Harenski, Vince D Calhoun, Juan R Bustillo, Brian W Haas, Jean Decety, Keith A Harenski, Michael F Caldwell, Gregory J Van Rybroek, Michael Koenigs, David M Thornton, Kent A Kiehl
Psychotic disorders are associated with neurobehavioral impairments in mental state attribution (mentalizing). These impairments are most severe in psychotic patients with elevated symptom levels, particularly negative and cognitive symptoms. There have been few studies of functional connectivity related to mentalizing in psychotic disorders and associations with symptoms. We conducted a functional MRI study of affective mentalizing in individuals with psychotic disorders and varying symptom levels (positive, negative, cognitive)...
November 6, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29145707/relationship-between-testosterone-in-serum-saliva-and-urine-during-treatment-with-intramuscular-testosterone-undecanoate-in-gender-dysphoria-and-male-hypogonadism
#12
Y Lood, E Aardal-Eriksson, C Webe, J Ahlner, B Ekman, J Wahlberg
Long-term testosterone replacement therapy is mainly monitored by trough levels of serum testosterone (S-T), while urinary testosterone (U-T) is used by forensic toxicology to evaluate testosterone doping. Testosterone in saliva (Sal-T) may provide additional information and simplify the sample collection. We aimed to investigate the relationships between testosterone measured in saliva, serum and urine during standard treatment with 1,000 mg testosterone undecanoate (TU) every 12th week during 1 year. This was an observational study...
November 16, 2017: Andrology
https://www.readbyqxmd.com/read/29145187/diogenes-syndrome
#13
Frédéric Assal
Diogenes syndrome (DS) is not a specific disease but a real neurobehavioral syndrome, characterized by severe domestic squalor, pathological hoarding, lack of insight into the condition, and no need for help. DS can be secondary when associated to psychosis or bipolar disorder, or primary when it occurs as a single entity, usually in the elderly. DS is a clinically complex transnosographic syndrome for which multidimensional approaches need to be considered: medical, psychiatric, neurological, social, scientific, and ethical...
2018: Frontiers of Neurology and Neuroscience
https://www.readbyqxmd.com/read/29145003/the-importance-of-saprinus-semistriatus-coleoptera-histeridae-for-estimating-the-minimum-post-mortem-interval
#14
I Szelecz, N Feddern, C V W Seppey, J Amendt, E A D Mitchell
In forensic science, the use of entomological evidence to estimate the minimum post-mortem interval can be crucial. However, not all cadaver-visiting insects are equally useful. Our focus is on the histerid beetle Saprinus semistriatus (Scriba 1790) (Histeridae; Coleoptera). Histeridae are common predators that feed mainly on dipteran larvae on carrion and dung. We review 23 publications mentioning this species and provide new experimental data on its temporal pattern beneath and on hanging pig cadavers. In a field experiment near Neuchâtel, Switzerland, we recorded the abundance of S...
November 10, 2017: Legal Medicine
https://www.readbyqxmd.com/read/29143486/violent-behaviour-in-early-psychosis-patients-can-we-identify-clinical-risk-profiles
#15
Valerie Moulin, Julie Palix, Philippe Golay, Alexandre Dumais, Mohammad Mehdi Gholamrezaee, Agathe Azzola, Philipp S Baumann, Luis Alameda, Philippe Conus
AIMS: The objective of this study is to explore, within a sample of early psychosis patients (EPP), if subgroups regarding rate of violent behaviour (VB) against others can be identified on the basis of dynamic risk factors (treatment modifiable characteristics). METHODS: In a sample of 265 EPP, treated at the Treatment and Early Intervention in Psychosis Program in Lausanne, we conducted a latent-class analysis on the basis of the main dynamic VB risk factors (substance use disorder [SUD], positive symptoms, insight, and impulsivity)...
November 15, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29143430/power-discourse-and-resistance-poststructuralist-influences-in-nursing
#16
Dave Holmes, Marilou Gagnon
Based on our respective research programs (psychiatry, forensic psychiatry, public health, HIV/AIDS, harm reduction) this article aims to use purposely non-conventional means to present the substantial contribution of poststructuralist perspectives to knowledge development in nursing science in general and in our current research in particular. More specifically, we call on the work of Michel Foucault and Deleuze & Guattari to politicize nursing science using examples from our empirical research programs with marginal and often highly marginalized populations...
November 15, 2017: Nursing Philosophy: An International Journal for Healthcare Professionals
https://www.readbyqxmd.com/read/29143327/location-of-artifacts-deposited-by-the-blow-fly-lucilia-cuprina-after-feeding-on-human-blood-at-simulated-indoor-crime-scenes
#17
Annalisa Durdle, Timothy J Verdon, Robert John Mitchell, Roland A H van Oorschot
Human DNA profiles can be obtained from fly artifacts (feces and regurgitant) when a fly has been feeding on biological material, sometimes 2 years after deposition. Morphological similarity between artifacts and spots of unaltered biological material make it difficult to distinguish between them, and presumptive and confirmatory forensic tests are unreliable in making the distinction. Knowing possible artifact locations will assist investigators in recognizing where DNA contamination might occur. Flies were released into a house with human blood available under a variety of different climatic and lighting conditions...
November 16, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/29143074/-additional-emergency-medical-measures-in-trauma-associated-cardiac-arrest
#18
B Ondruschka, C Baier, J Dreßler, A Höch, M Bernhard, C Kleber, C Buschmann
INTRODUCTION: More than half of all traumatic deaths happen in prehospital settings. Until now, there have been no long-term studies examining the actual additive treatment during trauma-associated cardiopulmonary resuscitation (tCPR), including pleural decompression, pericardiocentesis, tourniquets and external stabilization of the pelvis. The present cohort study evaluated forensic autopsy reports of trauma deaths occurring at the scene with respect to additive actions in preclinical tCPR as well as the potentially preventable nature of the individual death cases...
November 15, 2017: Der Anaesthesist
https://www.readbyqxmd.com/read/29141499/gastrointestinal-causes-of-sudden-unexpected-death-a-review
#19
Ritesh G Menezes, Saba Ahmed, Syed Bilal Pasha, Syed Ather Hussain, Huda Fatima, Magdy A Kharoshah, Mohammed Madadin
Gastrointestinal conditions are a less common cause of sudden unexpected death when compared to other conditions such as cardiovascular conditions, but they are equally important. Various congenital and acquired gastrointestinal conditions that have resulted in sudden unexpected death are discussed. The possible lethal mechanisms behind each condition, along with any associated risk factors or secondary diseases, have been described. Through this article, we aim to highlight the need for physicians to prevent death in such conditions by ensuring that subclinical cases are diagnosed correctly before it is too late and by providing timely and efficacious treatment to the patient concerned...
January 1, 2017: Medicine, Science, and the Law
https://www.readbyqxmd.com/read/29140802/characterization-with-scanning-electron-microscopy-energy-dispersive-x-ray-spectrometry-of-microtraces-from-the-ligature-mean-in-hanging-mechanical-asphyxia-a-series-of-forensic-cases
#20
Francesca Maghin, Salvatore Ambrogio Andreola, Michele Boracchi, Guendalina Gentile, Francesca Maciocco, Riccardo Zoja
The authors applied scanning electron microscopy with energy-dispersive x-ray spectrometry to the furrow derived from hanging means. The study was conducted with the purpose to detect possible extraneous microtraces, deriving from the ligature, that could have had an interaction with the cutaneous biological matrix, thanks to a transfert mechanism, in the proximities of the lesion.Fifteen cutaneous samples of the furrow and an equal number of fragments of graphite tape, directly positioned on the lesion produced by the ligature mean and used as a "conductor" of possible traces, were analyzed using scanning electron microscopy with energy-dispersive x-ray spectrometry...
November 15, 2017: American Journal of Forensic Medicine and Pathology
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