Thang Duc Vu, Duc-Viet Nguyen, Min Zin Oo, Mohamed Alaa, Ervin Marquez Ocampo, Suganya Cheyyatraivendran Arularasu, Phyo Wai Win, Nurdiyana Ja'afar, Goh Si-Guim, Patsy Ong, Lian Kah Ti, Arthur Mark Richards, Theo Kofidis
OBJECTIVES: Favourable outcomes with mitral annuloplasty have been achieved with transapical cardioscopic (TAC) surgery in a survival animal model. In addition, experimental TAC on a non-survival animal model also showed adequate access to remove the native mitral valve and implant a prosthetic valve, but the surgical procedure took a long time and lacked follow-up data. The goal of this study was to develop a clinically translatable TAC mitral valve replacement (MVR) procedure using technical and instrumental refinements to reduce the surgical time and to evaluate functional recovery and short-term durability using a survival porcine model...
March 26, 2018: Interactive Cardiovascular and Thoracic Surgery