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SPRINT Trial

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https://www.readbyqxmd.com/read/29141496/power-and-pacing-calculations-based-on-real-time-locating-data-from-a-cross-country-skiing-sprint-race
#1
Mikael Swarén, Anders Eriksson
Pacing strategies in cross-country skiing have been investigated in several studies. However, none of the previous studies have been verified by collected skiing data giving the skiing velocities along a measured track. These can be used to calculate the propulsive power output. Collected real-time positioning data from a cross-country sprint skiing race were used to estimate the propulsive power by applying a power balance model. Analyses were made for the time-trial and the final for one female and one male skier...
November 15, 2017: Sports Biomechanics
https://www.readbyqxmd.com/read/29140912/reliable-testing-battery-for-assessing-physical-qualities-of-elite-academy-rugby-league-players
#2
Nick Dobbin, Richard Hunwicks, Jamie Highton, Craig Twist
Dobbin, N, Hunwicks, R, Highton, J, and Twist, C. Reliable testing battery for assessing physical qualities of elite academy rugby league players. J Strength Cond Res XX(X): 000-000, 2017-This study assessed the interday reliability of a testing battery for the assessment of physical qualities of rugby league players. Fifty players (age 17.1 ± 1.1 years; stature 181.3 ± 6.3 cm; and body mass 89.0 ± 11.6 kg) from 3 Super League academies participated in this study. Tests of countermovement jump performance, 10- and 20-m sprint performance, change of direction, medicine ball throw, and a modified Yo-Yo Intermittent Recovery Test Level 1 (prone Yo-Yo IR1) were completed on 3 separate occasions...
November 14, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29133606/effects-of-bariatric-surgery-in-obese-patients-with-hypertension-the-gateway-randomized-trial-gastric-bypass-to-treat-obese-patients-with-steady-hypertension
#3
Carlos Aurelio Schiavon, Angela Cristine Bersch-Ferreira, Eliana Vieira Santucci, Juliana Dantas Oliveira, Camila Ragne Torreglosa, Priscila Torres Bueno, Julia Caldas Frayha, Renato Nakagawa Santos, Lucas Petri Damian, Patricia Malvina Noujaim, Helio Halpern, Frederico L J Monteiro, Ricardo Vitor Cohen, Carlos H Uchoa, Marcio Gonçalves de Souza, Celso Amodeo, Luiz Bortolotto, Dimas Ikeoka, Luciano F Drager, Alexandre Biasi Cavalcanti, Otavio Berwanger
BACKGROUND : Recent research efforts on bariatric surgery have focused on metabolic and diabetes mellitus resolution. Randomized trials designed to assess the impact of bariatric surgery in patients with obesity and hypertension are needed. METHODS : In this randomized, single-center, nonblinded trial, we included patients with hypertension (using ≥2 medications at maximum doses or >2 at moderate doses) and a body mass index between 30.0 and 39.9 kg/m(2) Patients were randomized to Roux-en-Y gastric bypass plus medical therapy or medical therapy alone...
November 13, 2017: Circulation
https://www.readbyqxmd.com/read/29133522/systolic-blood-pressure-response-in-sprint-systolic-blood-pressure-intervention-trial-and-accord-action-to-control-cardiovascular-risk-in-diabetes-a-possible-explanation-for-discordant-trial-results
#4
Chenxi Huang, Sanket S Dhruva, Andreas C Coppi, Frederick Warner, Shu-Xia Li, Haiqun Lin, Khurram Nasir, Harlan M Krumholz
BACKGROUND: SPRINT (Systolic Blood Pressure Intervention Trial) and the ACCORD (Action to Control Cardiovascular Risk in Diabetes) blood pressure trial used similar interventions but produced discordant results. We investigated whether differences in systolic blood pressure (SBP) response contributed to the discordant trial results. METHODS AND RESULTS: We evaluated the distributions of SBP response during the first year for the intensive and standard treatment groups of SPRINT and ACCORD using growth mixture models...
November 13, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29125040/reliability-of-horizontal-force-velocity-power-profiling-during-short-sprint-running-accelerations-using-radar-technology
#5
Kim David Simperingham, John B Cronin, Simon N Pearson, Angus Ross
Radar technology can be used to perform horizontal force-velocity-power profiling during sprint-running. The aim of this study was to determine the reliability of radar-derived profiling results from short sprint accelerations. Twenty-seven participants completed three 30 m sprints (intra-day analysis), and nine participants completed the testing session on four separate days (inter-day analysis). The majority of radar-derived kinematic and kinetic descriptors of short sprint performance had acceptable intra-day and inter-day reliability [intraclass correlation coefficient (ICC) ≥ 0...
November 10, 2017: Sports Biomechanics
https://www.readbyqxmd.com/read/29108901/keto-adaptation-enhances-exercise-performance-and-body-composition-responses-to-training-in-endurance-athletes
#6
Fionn T McSwiney, Bruce Wardrop, Parker N Hyde, Richard A Lafountain, Jeff S Volek, Lorna Doyle
BACKGROUND: Low-carbohydrate diets have recently grown in popularity among endurance athletes, yet little is known about the long-term (>4 wk) performance implications of consuming a low-carbohydrate high fat ketogenic diet (LCKD) in well-trained athletes. METHODS: Twenty male endurance-trained athletes (age 33 ± 11y, body mass 80 ± 11kg; BMI 24.7 ± 3.1 kg/m(2)) who habitually consumed a carbohydrate-based diet, self-selected into a high-carbohydrate (HC) group (n = 11, %carbohydrate:protein:fat = 65:14:20), or a LCKD group (n = 9, 6:17:77)...
November 3, 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/29101186/bp-reduction-kidney-function-decline-and-cardiovascular-events-in-patients-without-ckd
#7
Rita Magriço, Miguel Bigotte Vieira, Catarina Viegas Dias, Lia Leitão, João Sérgio Neves
BACKGROUND AND OBJECTIVES: In the Systolic Blood Pressure Intervention Trial (SPRINT), intensive systolic BP treatment (target <120 mm Hg) was associated with fewer cardiovascular events and higher incidence of kidney function decline compared with standard treatment (target <140 mm Hg). We evaluated the association between mean arterial pressure reduction, kidney function decline, and cardiovascular events in patients without CKD. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We categorized patients in the intensive treatment group of the SPRINT according to mean arterial pressure reduction throughout follow-up: <20, 20 to <40, and ≥40 mm Hg...
November 3, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29099836/how-does-the-ball-influence-the-performance-of-change-of-direction-and-sprint-tests-in-para-footballers-with-brain-impairments-implications-for-evidence-based-classification-in-cp-football
#8
Raúl Reina, José Manuel Sarabia, Carla Caballero, Javier Yanci
The aims of this study were: i) to analyze the reliability and validity of three tests that require sprinting (10 m, 25 m, 40 m), accelerations/decelerations (Stop and Go Test) and change of direction (Illinois Agility Test), with and without ball, in para-footballers with neurological impairments, and ii) to compare the performance in the tests when ball dribbling is required and to explore the practical implications for evidence-based classification in cerebral palsy (CP)-Football. Eighty-two international para-footballers (25...
2017: PloS One
https://www.readbyqxmd.com/read/29091470/acute-ingestion-of-caffeinated-chewing-gum-improves-repeated-sprint-performance-of-team-sports-athletes-with-low-habitual-caffeine-consumption
#9
Mark Evans, Peter Tierney, Nicola Gray, Greg Hawe, Maria Macken, Brendan Egan
The effects of acute ingestion of caffeine on short-duration high intensity performance are equivocal, while studies of novel modes of delivery and the efficacy of low doses of caffeine are warranted. The aims of the present study were to investigate the effect of acute ingestion of caffeinated chewing gum on repeated sprint performance (RSP) in team sport athletes, and whether habitual caffeine consumption alters the ergogenic effect, if any, on RSP. Eighteen male team sports athletes undertook four RSP trials using a 40 m maximum shuttle run test (MST), which incorporates 10x40 m sprints with 30 s between the start of each sprint...
November 1, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29083126/exercise-to-rest-ratios-in-rsa-training-in-women-s-soccer
#10
Bruno Ruscello, Mario Esposito, Filippo Partipilo, Dalila DI Cicco, Cristoforo Filetti, Laura Pantanella, Stefano D'Ottavio
BACKGROUND: To investigate the applicability of three different exercise to rest ratios in RSA training in women's soccer players, applying those ones already adopted in male adult and young players, when performing three different sprinting modes (straight, shuttle and sprinting with changing of direction). METHODS: 15 trained female soccer players (height: 1.65 ± 0.06 m; weight: 59.3 ± 9.0 kg; BMI 21.6 ± 2.7 kg·m-2; age: 23.3±5.9 years) participated to the study...
October 27, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/29076961/six-sessions-of-sprint-interval-training-improves-running-performance-in-trained-athletes
#11
Jerome Koral, Dustin J Oranchuk, Roberto Herrera, Guillaume Y Millet
Sprint interval training (SIT) is gaining popularity with endurance athletes. Various studies have shown that SIT allows similar or greater endurance, strength, and power performance improvements than traditional endurance training, but demands less time and volume. One of the main limitations in SIT research is that most studies were performed in a laboratory using expensive treadmills or ergometers. The aim of this study was to assess the performance effects of a novel short term and highly accessible training protocol based on maximal shuttle runs in the field (SIT-F)...
October 20, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29075200/neuromuscular-adaptations-to-multimodal-injury-prevention-programs-in-youth-sports-a-systematic-review-with-meta-analysis-of-randomized-controlled-trials
#12
Oliver Faude, Roland Rössler, Erich J Petushek, Ralf Roth, Lukas Zahner, Lars Donath
Objective: Neuromuscular injury prevention programs (IPP) can reduce injury rate by about 40% in youth sport. Multimodal IPP include, for instance, balance, strength, power, and agility exercises. Our systematic review and meta-analysis aimed to evaluate the effects of multimodal IPP on neuromuscular performance in youth sports. Methods: We conducted a systematic literature search including selected search terms related to youth sports, injury prevention, and neuromuscular performance. Inclusion criteria were: (i) the study was a (cluster-)randomized controlled trial (RCT), and (ii) investigated healthy participants, up to 20 years of age and involved in organized sport, (iii) an intervention arm performing a multimodal IPP was compared to a control arm following a common training regime, and (iv) neuromuscular performance parameters (e...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/29072676/comparison-of-sprinting-vs-non-sprinting-to-wean-nasal-continuous-positive-airway-pressure-off-in-very-preterm-infants
#13
N Eze, D Murphy, V Dhar, V K Rehan
OBJECTIVE: Though nasal continuous positive airway pressure (NCPAP) is commonly used for non-invasive neonatal respiratory support, the optimal method of weaning NCPAP is not established. In this prospective, two-center randomized control trial we hypothesize that gradually increasing spontaneous breathing time off NCPAP increases successful weaning from NCPAP in infants born <31 weeks gestational age. STUDY DESIGN: Infants were randomized to one of the two NCPAP weaning protocols, a sprinting, that is, gradually increasing spontaneous breathing time off CPAP, protocol vs a non-sprinting (weaning pressure down) protocol...
October 26, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29065052/energy-drink-doses-of-caffeine-and-taurine-have-a-null-or-negative-effect-on-sprint-performance
#14
Owen Jeffries, Jessica Hill, Stephen D Patterson, Mark Waldron
This study investigated the effects of caffeine and taurine co-ingestion on repeat-sprint cycling performance and associated physiological and perceptual responses. In a double blind, cross-over, repeated measures study, 11 male participants (age 21 ± 2 years; stature 178 ± 7 cm; body mass 80 ± 13 kg) completed 10 x 6-s sprints on a cycle ergometer, each separated by 24-s, an hour after ingesting: caffeine (80 mg) and taurine (1 g), equivalent to the amount observed in popular commercial energy drinks, or placebo (maltodextrin ∼1 g) in a gelatine capsule...
October 23, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29058304/serious-adverse-events-among-sprint-trial-participants-taking-statins-at-baseline
#15
Marco D Huesch
BACKGROUND: Real-world evidence of statin side effects is potentially biased because statin use is neither randomized nor unblinded. An innovative study design can mitigate these biases. For example, in the recent ASCOT-LLA trial, patient-reported adverse events such as muscle pain and weakness were higher in the non-randomized and non-blinded setting than in the randomized, blinded setting. Less optimally, secondary re-analysis of clinical trials in which statin use is recorded and in which serious adverse events (SAEs) are adjudicated may be conducted...
December 2017: Drugs in R&D
https://www.readbyqxmd.com/read/29051347/bp-measurement-in-clinical-practice-time-to-sprint-to-guideline-recommended-protocols
#16
Paul E Drawz, Joachim H Ix
Hypertension is the leading chronic disease risk factor in the world and is especially important in patients with CKD, nearly 90% of whom have hypertension. Recently, in the Systolic BP Intervention Trial (SPRINT), intensive lowering of clinic systolic BP to a target <120 mm Hg, compared with a standard BP target of <140 mm Hg, reduced risk for cardiovascular disease and all-cause mortality. However, because BP was measured unobserved using an automated device, some investigators have questioned the ability to translate SPRINT results into routine clinical practice, in which measurement of BP is typically less standardized...
October 19, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/29046987/blood-pressure-parameters-and-their-associations-with-death-in-patients-with-chronic-kidney-disease
#17
REVIEW
Samaya Qureshi, Robert Lorch, Sankar D Navaneethan
PURPOSE OF REVIEW: Optimal blood pressure (BP) parameters among patients with chronic kidney disease (CKD) have been a matter of debate. This review critically evaluates recent literature to better define the associations of BP parameters and death among individuals with non-dialysis-dependent CKD. RECENT FINDINGS: Observational studies report a "U- or J-shaped" association between BP and all-cause mortality in CKD and caution-intensive BP lowering in the elderly...
October 18, 2017: Current Hypertension Reports
https://www.readbyqxmd.com/read/29045995/ingesting-a-sports-drink-enhances-simulated-ice-hockey-performance-while-reducing-perceived-effort
#18
Matthew Stephen Palmer, George Heigenhauser, MyLinh Duong, Lawrence L Spriet
This study determined whether ingesting a carbohydrate-electrolyte solution (CES) vs. progressive dehydration affected skeletal muscle glycogen use and performance in ice hockey players during simulated ice hockey exercise comprised of 3 active "periods". Seven males (21.3±0.3 years, 184.7±1.2 cm, 84.2±3.9 kg, and 49.6±1.8 mL·kg(-1)·min(-1)) performed a hockey-specific protocol on two occasions and either dehydrated progressively (NF), or stayed well-hydrated by ingesting a CES. Muscle biopsies were taken at rest, before the 3(rd) period (P3), and after the final sprint in the protocol...
October 18, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/29044764/estimated-glomerular-filtration-rate-and-the-risk-benefit-profile-of-intensive-blood-pressure-control-among-non-diabetic-patients-a-post-hoc-analysis-of-a-randomized-clinical-trial
#19
Yoshitsugu Obi, Kamyar Kalantar-Zadeh, Ayumi Shintani, Csaba P Kovesdy, Takayuki Hamano
BACKGROUND: The Systolic Blood Pressure Intervention Trial (SPRINT; ClinicalTrials. gov, NCT01206062) reported reduced cardiovascular events by intensive blood pressure (BP) control among hypertensive patients without diabetes. However, the risk-benefit profile of intensive BP control may differ across estimated glomerular filtration rate (eGFR) levels. METHODS: This is a post-hoc analysis of the SPRINT. Non-diabetic hypertensive adults (n=9,361) with eGFR >20 mL/min/1...
October 16, 2017: Journal of Internal Medicine
https://www.readbyqxmd.com/read/29040268/benefit-and-harm-of-intensive-blood-pressure-treatment-derivation-and-validation-of-risk-models-using-data-from-the-sprint-and-accord-trials
#20
Sanjay Basu, Jeremy B Sussman, Joseph Rigdon, Lauren Steimle, Brian T Denton, Rodney A Hayward
BACKGROUND: Intensive blood pressure (BP) treatment can avert cardiovascular disease (CVD) events but can cause some serious adverse events. We sought to develop and validate risk models for predicting absolute risk difference (increased risk or decreased risk) for CVD events and serious adverse events from intensive BP therapy. A secondary aim was to test if the statistical method of elastic net regularization would improve the estimation of risk models for predicting absolute risk difference, as compared to a traditional backwards variable selection approach...
October 2017: PLoS Medicine
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