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SPRINT Trial

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https://www.readbyqxmd.com/read/27905864/determining-friction-and-effective-loading-for-sled-sprinting
#1
Matt R Cross, Farhan Tinwala, Seth Lenetsky, Pierre Samozino, Matt Brughelli, Jean-Benoit Morin
Understanding the impact of friction in sled sprinting allows the quantification of kinetic outputs and the effective loading experienced by the athlete. This study assessed changes in the coefficient of friction (µk) of a sled sprint-training device with changing mass and speed to provide a means of quantifying effective loading for athletes. A common sled equipped with a load cell was towed across an athletics track using a motorised winch under variable sled mass (33.1-99.6 kg) with constant speeds (0...
December 1, 2016: Journal of Sports Sciences
https://www.readbyqxmd.com/read/27884231/guidelines-for-the-management-of-hypertension
#2
REVIEW
Aram V Chobanian
This article summarizes pertinent data from clinical trials on the effects of antihypertensive therapy on cardiovascular complications. Prior definitions of hypertension and blood pressure goals of therapy are discussed, and differences between national and international guidelines on such goals are summarized. The results of the SPRINT study are summarized, and the impact of this study on future goals of treatment is discussed. New recommendations are provided on blood pressure goals, and the effects such goals might have on clinical practice are discussed...
January 2017: Medical Clinics of North America
https://www.readbyqxmd.com/read/27872460/sprint-trial-and-blood-pressure-treatment-dr-gordon-guyatt-in-an-interview-with-dr-roman-jaeschke
#3
Gordon Guyatt, Roman Jaeschke
No abstract text is available yet for this article.
October 28, 2016: Polskie Archiwum Medycyny Wewnętrznej
https://www.readbyqxmd.com/read/27865822/ambulatory-blood-pressure-in-hypertensive-patients-with-inclusion-criteria-for-the-sprint-trial
#4
Alejandro de la Sierra, José R Banegas, Juan A Divisón, Manuel Gorostidi, Ernest Vinyoles, Juan J de la Cruz, Julián Segura, Luis M Ruilope
We aimed to characterize 24-hour blood pressure (BP) values and categories in patients with inclusion/exclusion criteria of the Systolic Blood Pressure Intervention (SPRINT) trial from the Spanish ABPM Registry. We selected patients older than 50 years, with office systolic BP (SBP) above 130 mm Hg and at high cardiovascular risk, but without diabetes, previous stroke, or symptomatic heart failure. Ambulatory BP was compared among BP categories. A total of 39,132 patients (34%) fulfilled inclusion criteria of SPRINT trial...
November 5, 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/27862904/baseline-blood-pressure-control-in-hispanics-characteristics-of-hispanics-in-the-systolic-blood-pressure-intervention-trial
#5
Carlos J Rodriguez, Carolyn H Still, Katelyn R Garcia, Lynne Wagenknecht, Suzanne White, Jeffrey T Bates, Margareth V Del Cid, Michael Lioudis, Nieves Lopez Barrera, Abel Moreyra, Henry Punzi, Robert J Ringer, William C Cushman, Gabriel Contreras, Karen Servilla, Michael Rocco
The Systolic Blood Pressure Intervention Trial (SPRINT) tested whether a systolic blood pressure (SBP) value <120 mm Hg reduces adverse clinical outcomes compared with the goal of <140 mm Hg. Here the authors describe the baseline characteristics of Hispanic participants in SPRINT. Nondiabetic hypertensive patients 50 years and older with SBP 130-180 mm Hg taking zero to four blood pressure (BP) medications were enrolled from the mainland United States and Puerto Rico. Cross-sectional, bivariate analysis was employed comparing sociodemographic and clinical factors in Hispanics vs non-Hispanics...
November 14, 2016: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/27849563/effect-of-intensive-versus-standard-clinic-based-hypertension-management-on-ambulatory-blood-pressure-results-from-the-sprint-systolic-blood-pressure-intervention-trial-ambulatory-blood-pressure-study
#6
Paul E Drawz, Nicholas M Pajewski, Jeffrey T Bates, Natalie A Bello, William C Cushman, Jamie P Dwyer, Lawrence J Fine, David C Goff, William E Haley, Marie Krousel-Wood, Andrew McWilliams, Dena E Rifkin, Yelena Slinin, Addison Taylor, Raymond Townsend, Barry Wall, Jackson T Wright, Mahboob Rahman
: The effect of clinic-based intensive hypertension treatment on ambulatory blood pressure (BP) is unknown. The goal of the SPRINT (Systolic Blood Pressure Intervention Trial) ambulatory BP ancillary study was to evaluate the effect of intensive versus standard clinic-based BP targets on ambulatory BP. Ambulatory BP was obtained within 3 weeks of the 27-month study visit in 897 SPRINT participants. Intensive treatment resulted in lower clinic systolic BP (mean difference between groups=16...
November 14, 2016: Hypertension
https://www.readbyqxmd.com/read/27849116/reliability-of-salivary-cortisol-and-immunoglobulin-a-measurements-from-the-ipro%C3%A2-before-and-after-sprint-cycling-exercise
#7
Luke A Macdonald, Phillip M Bellinger, Clare L Minahan
BACKGROUND: The purpose of this study was to evaluate the inter-day reliability of the IPRO method for determining resting and post-exercise salivary cortisol (sCort) and rate of salivary Immunoglobulin-A (sIgA) secretion. METHODS: Fourteen males (32±11 years) performed two trials (T1 and T2) separated by 7 d, comprising saliva sampling before and 15 min after completion of two, 30-s Wingate Anaerobic Tests separated by 3.5 min (2 x WAnT). sCort increased after the 2 x WAnT in both trials (T1: p<0...
November 16, 2016: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/27849114/effects-of-in-season-short-term-aerobic-and-high-intensity-interval-training-program-on-repeated-sprint-ability-and-jump-performance-in-handball-players
#8
Souhail Hermassi, Jørgen Ingebrigtsen, René Schwesig, Georg Fieseler, Karl S Delank, Karim Chamari, Roy J Shephard, Mohamed S Chelly
BACKGROUND: This study examined the effects of a 7-week in-season aerobic and high-intensity interval-training program on performance tests linked to successful handball play (e.g., repeated sprint and jumping ability). METHODS: Thirty participants (age 17.0 ± 1.2 years, body mass 81.1 ± 3.4 kg, height 1.82± 0.07 m) performed a Yo-Yo Intermittent Recovery Test level 1 (Yo-Yo IR1), a squat (SJ) and a countermovement jump test (CMJ), as well as a repeated sprint ability test (RSA)...
November 16, 2016: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/27842710/-hypertension-and-coronary-artery-disease-new-concept
#9
G Lefèvre, E Puymirat
Hypertension is the most important preventable cause of heart disease and stroke worldwide. More than 1 in 5 adults worldwide have raised blood pressure - a condition that causes around half of all deaths from stroke and heart disease. Complications from hypertension account for 9.4 million deaths worldwide every year. During the last decade, the association between blood pressure reduction from above-normal initial values and cardiovascular-risk has been documented in a large number of randomized trials...
November 11, 2016: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/27811329/effects-of-the-fifa-11-training-program-on-injury-prevention-and-performance-in-football-players-a-systematic-review-and-meta-analysis
#10
Mansueto Gomes Neto, Cristiano Sena Conceição, Alécio Jorge Alves de Lima Brasileiro, Camila Santana de Sousa, Vitor Oliveira Carvalho, Fabio Luciano Arcanjo de Jesus
OBJECTIVE: To investigate the effects of FIFA 11 training on injury prevention and performance in football players. DESIGN AND METHODS: Systematic review and meta-analysis. We conducted a systematic search using four databases (CINAHL, Cochrane Library, EMBASE, and PubMed) to find controlled trials evaluating the effects of FIFA 11 on injury prevention and performance among football players. Weighted mean differences, standard mean differences, risk ratios, and 95% confidence intervals were calculated, and heterogeneity was assessed using the I(2) test...
November 2, 2016: Clinical Rehabilitation
https://www.readbyqxmd.com/read/27806010/warm-up-for-sprint-swimming-race-pace-or-aerobic-stimulation-a-randomized-study
#11
Henrique P Neiva, Mário C Marques, Tiago M Barbosa, Mikel Izquierdo, João L Viana, Ana M Teixeira, Daniel A Marinho
The aim of this study was to compare the effects of two different warm-up intensities on 100m swimming performance in a randomized controlled trial. Thirteen competitive swimmers performed two 100m freestyle time-trials on separate days after either control or experimental warm-up, in a randomized design. The control warm-up included a typical race-pace set (4x25m), while the experimental warm-up included an aerobic set (8x50m at 98-102% of critical velocity). Cortisol, testosterone, blood lactate ([La]), oxygen uptake (VO2), heart rate, core (Tcore and Tcorenet) and tympanic temperatures, and rating of perceived exertion (RPE) were monitored...
October 27, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27803631/assessment-of-technical-skills-in-young-soccer-goalkeepers-reliability-and-validity-of-two-goalkeeper-specific-tests
#12
Ricardo Rebelo-Gonçalves, António J Figueiredo, Manuel J Coelho-E-Silva, Antonio Tessitore
The purpose of this study was to evaluate the reproducibility and validity of two new tests designed to examine goalkeeper-specific technique. Twenty-six goalkeepers (14.49 ± 2.52 years old) completed two trial sessions, each separated by one week, to evaluate the reproducibility of the Sprint-Keeper Test (S-Keeper) and the Lateral Shuffle-Keeper Test (LS-Keeper). Construct validity was assessed among forty goalkeepers (14.49 ± 1.71 years old) by competitive level (elite versus non-elite), after controlling for chronological age...
September 2016: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/27771852/threshold-and-target-for-blood-pressure-lowering-in-the-elderly
#13
Guido Grassi, Fosca Quarti-Trevano, Anna Casati, Raffaella Dell'Oro
PURPOSE OF REVIEW: Detection of elevated blood pressure values in elderly patients represents a common clinical condition associated with an increased cardiovascular risk. This has been shown to be the case in both systodiastolic and isolated systolic hypertension as well. However, despite the evidence of the benefits of the blood pressure lowering intervention in terms of reduction of cardiovascular morbidity and mortality, at least two issues related to antihypertensive drug treatment in aged individuals are still undefined: (1) the blood pressure threshold at which antihypertensive drug should be initiated and (2) the blood pressure goals of the therapeutic intervention...
December 2016: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/27771799/salbutamol-effects-on-systemic-potassium-dynamics-during-and-following-intense-continuous-and-intermittent-exercise
#14
Muath M Altarawneh, Aaron Petersen, Robert Smith, David M Rouffet, Francois Billaut, Ben D Perry, Victoria L Wyckelsma, Antony Tobin, Michael J McKenna
PURPOSE: Salbutamol inhalation is permissible by WADA in athletic competition for asthma management and affects potassium regulation, which is vital for muscle function. Salbutamol effects on arterial potassium concentration ([K(+)]a) during and after high-intensity continuous exercise (HIcont) and intermittent exercise comprising repeated, brief sprints (HIint), and on performance during HIint are unknown and were investigated. METHODS: Seven recreationally active men participated in a double-blind, randomised, cross-over design, inhaling 1000 µg salbutamol or placebo...
October 22, 2016: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/27758750/-towards-new-targets-in-the-treatment-of-hypertension
#15
Anne-Laure Faucon, Anne-Marie Madjalian, Guillaume Bobrie, Laurence Amar, Michel Azizi
Blood pressure is a major determinant of cardiovascular risk. Blood pressure target to reach with antihypertensive therapy, and the population to whom it should apply, remain debatted. Blood pressure goals established by scientific societies may be revised after the publication of the US multicenter SPRINT study results (Systolic Blood Pressure Intervention Trial) obtained in 2015. Analysis of the generalizability of the SPRINT results shows that they may not be directly applied to the french population which is at lower risk than the US population and would have major medical and economic implications...
October 2016: Médecine Sciences: M/S
https://www.readbyqxmd.com/read/27754309/lbos-03-04-strict-blood-pressure-control-as-shown-in-the-sprint-trial-can-it-be-generalized-to-all-asian-populations
#16
Satoshi Hoshide, Yuichiro Yano, Hajime Haimoto, Kayo Yamagiwa, Kiyoshi Uchiba, Shoichiro Nagasaka, Yoshio Matsui, Akira Nakamura, Motoki Fukutomi, Kazuo Eguchi, Joji Ishikawa, Kazuomi Kario
OBJECTIVE: The SPRINT (Systolic Blood Pressure Intervention Trial) recently demonstrated that strict blood pressure (BP) control resulted in a lower cardiovascular disease (CVD) risk compared to standard BP control, however, this association was not observed regarding the incidence of stroke. Previous studies revealed that the contribution of BP as a risk factor was higher for stroke incidence than for any other CVD, especially in Asian populations. It is thus not clear whether the results of the SPRINT can be generalized to all Asian populations...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27754290/br-08-2-cardiovascular-risk-assessment-in-hypertensives-with-ckd
#17
Jongha Park
Cardiovascular (CV) risk assessment is not easy in chronic kidney disease (CKD) patients. Age, male sex, race, family history of CV disease, smoking status and diabetes should be considered as CV risk factors as the general population. It is also accepted that hypertension (HTN) is associated with the greater risk of CV complications in this population. However, there are some concerns in this issue.First, supporting evidence for specific blood pressure (BP) targets in CKD is scarce. Many observational studies reported a J-shaped association between BP level and CV mortality unlike a linear association in the general population...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27754191/sp-05-4-implications-of-the-sprint-trial-asian-perspective
#18
Sadayoshi Ito
SPRINT is one of the landmark studies, demonstrating that extensive blood pressure (BP) control (BP < 120 mmHg) is superior to standard control (BP < 140 mmHg) in preventing cardiovascular event (CVE). Subjects recruited were older than 50 years without diabetes and had increased risk of CVE. Heart failure, death from cardiovascular cause and death from any cause were major endpoints reduced by extensive BP control. In subgroup analysis, whole spectrum of patients were benefitted. Contrary to several previous studies, this study provides strong evidence for the beneficial effect of extensive BP reduction...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27754190/sp-05-3-does-the-sprint-trial-change-the-target-blood-pressure-in-the-elderly
#19
Clive Rosendorff
Many guidelines for the management of hypertension have recommended that the goal of antihypertensive treatment in the elderly (usually specified as 80 years or above) should be less than 150/90 mmHg. SPRINT included subjects 50 years or above, and a substantial proportion of subjects 75 years and older. These are individuals at high risk for adverse cardiovascular events because of high prevalence of hypertension and atherosclerotic disease. The less stringent BP goals have been based on a percieved danger of lowering BP to levels that threaten vital organ pefusion (myocardium, brain, kidney)...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27754189/sp-05-2-what-should-be-the-target-blood-pressure-for-ckd-with-overt-proteinuria
#20
Daniel W Jones
Hypertension and Chronic Kidney Disease are both common. The vast majority of patients with chronic kidney disease (CKD) have hypertension. Hypertension can be both a cause and a result of CKD. Many patients with CKD, both diabetic and non-diabetic have overt proteinuria (>300 mg/day). Patients with proteinuria are at higher risk for progression of kidney disease and for atherosclerosis. Because patients with CKD are often excluded from hypertension trials with hard outcomes, there has been until recently less data than ideal to consider in making decisions...
September 2016: Journal of Hypertension
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