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https://www.readbyqxmd.com/read/28529721/the-impact-of-antihypertensives-on-kidney-disease
#1
REVIEW
Diego F Marquez, Gema Ruiz-Hurtado, Luis Ruilope
Arterial hypertension and chronic kidney disease (CKD) are intimately related. The control of blood pressure (BP) levels is strongly recommended in patients with CKD in order to protect the kidney against the accompanying elevation in global cardiovascular (CV) risk. Actually, the goal BP in patients with CKD involves attaining values <140/90 mmHg except if albuminuria is present. In this case, it is often recommended to attain values <130/80 mmHg, although some guidelines still recommend <140/90 mmHg...
2017: F1000Research
https://www.readbyqxmd.com/read/28527424/influence-of-chronic-stretching-on-muscle-performance-systematic-review
#2
D M Medeiros, C S Lima
The aim of the current study was to investigate the influence of chronic stretching on muscle performance (MP) by a systematic review. The search strategy included MEDLINE, PEDro, Cochrane CENTRAL, LILACS, and manual search from inception to June 2016. Randomized and controlled clinical trials, non-randomized, and single group studies that have analyzed the influence of flexibility training (FT) (using any stretching technique) on MP were included. Differently, studies with special populations (children, elderly, and people with any dysfunction/disease), and articles that have used FT protocols shorter than three weeks or 12 sessions were excluded...
May 17, 2017: Human Movement Science
https://www.readbyqxmd.com/read/28512184/effect-of-intensive-blood-pressure-lowering-on-left-ventricular-hypertrophy-in-patients-with-hypertension-the-systolic-blood-pressure-intervention-sprint-trial
#3
Elsayed Z Soliman, Walter T Ambrosius, William C Cushman, Zhu-Ming Zhang, Jeffrey T Bates, Javier A Neyra, Thaddeus Y Carson, Leonardo Tamariz, Lama Ghazi, Monique E Cho, Brian P Shapiro, Jiang He, Lawrence J Fine, Cora E Lewis
Background -It is currently unknown whether intensive blood pressure (BP) lowering beyond that recommended would lead to more lowering of the risk of Left ventricular hypertrophy (LVH) in patients with hypertension, and whether reducing the risk of LVH explains the reported cardiovascular disease (CVD) benefits of intensive BP lowering in this population. Methods -This analysis included 8,164 participants (mean age 67.9 years, 35.3% women, 31.2% blacks) with hypertension but no diabetes from the Systolic Blood Pressure Intervention (SPRINT) Trial; 4,086 randomly assigned to intensive BP lowering (target systolic BP<120mmHg) and 4,078 assigned to standard BP lowering (target systolic BP <140mmHg)...
May 16, 2017: Circulation
https://www.readbyqxmd.com/read/28508114/oral-l-menthol-reduces-thermal-sensation-increases-work-rate-and-extends-time-to-exhaustion-in-the-heat-at-a-fixed-rating-of-perceived-exertion
#4
T R Flood, M Waldron, O Jeffries
PURPOSE: The study investigated the effect of a non-thermal cooling agent, L-menthol, on exercise at a fixed subjective rating of perceived exertion (RPE) in a hot environment. METHOD: Eight male participants completed two trials at an exercise intensity between 'hard' and 'very hard', equating to 16 on the RPE scale at ~35 °C. Participants were instructed to continually adjust their power output to maintain an RPE of 16 throughout the exercise trial, stopping once power output had fallen by 30%...
May 15, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28492286/has-the-sprint-trial-introduced-a-new-blood-pressure-goal-in-hypertension
#5
REVIEW
Gema Ruiz-Hurtado, José R Banegas, Pantelis A Sarafidis, Massimo Volpe, Bryan Williams, Luis M Ruilope
SPRINT is the first randomized, controlled trial showing that a systolic blood-pressure goal of <120 mmHg can be attained with cardiovascular benefits in a select group of patients with hypertension and an elevated cardiovascular risk with different origins. Although the patient population with characteristics like those in SPRINT makes up only 20-30% of the total hypertensive population, SPRINT is a landmark study that highlights the need to consider lower blood- pressure goals in the treatment of hypertension...
May 11, 2017: Nature Reviews. Cardiology
https://www.readbyqxmd.com/read/28486332/short-term-heat-acclimation-and-precooling-independently-and-combined-improve-5-km-running-performance-in-the-heat
#6
C A James, A J Richardson, A G B Willmott, P W Watt, O R Gibson, N S Maxwell
Following heat acclimation (HA), endurance running performance remains impaired in hot vs temperate conditions. Combining HA with precooling demonstrates no additive benefit in intermittent sprint, or continuous cycling exercise protocols, during which heat strain may be less severe compared to endurance running. This study investigated the effect of short-term heat acclimation (STHA) combined with mixed-methods precooling, on endurance running performance and directly compared precooling and HA. Nine amateur trained runners completed 5 km treadmill time trials in the heat (32°C, 60% RH) under four conditions; no intervention (CON), precooling (PC), short-term heat acclimation (5 days - HA) and short-term heat acclimation with precooling (HA+PC)...
May 5, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28483560/the-influence-of-a-12-carbohydrate-electrolyte-beverage-on-self-paced-soccer-specific-exercise-performance
#7
Liam D Harper, Emma J Stevenson, Ian Rollo, Mark Russell
OBJECTIVES: To assess the physiological and performance effects of a 12% carbohydrate-electrolyte beverage consumed at practically applicable time-points (i.e., before each half) throughout simulated soccer match-play. DESIGN: Randomised, counterbalanced, crossover. METHODS: Fed players (n=15) performed 90-min of soccer-specific exercise (including self-paced exercise at the end of each half). Players consumed carbohydrate-electrolyte (CHO; 60g×500ml(-1), Na(+) 205mg×500ml(-1)), placebo-electrolyte (PL) or water (Wat) beverages at the end of the warm-up (250ml) and half-time (250ml plus ad-libitum water)...
April 21, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28480693/factors-determining-800-m-running-performance-in-young-male-athletes
#8
Ramon Cruz, Romulo C de Moraes Bertuzzi, Danilo L Alves, Rafael Azevedo, Phelipe H Cardoso Castro, Jefferson Verbena Freitas, Adriano E Lima-Silva, Fernando R de Oliveira, Jorge R Perrout Lima
BACKGROUND: The aim of the present study was to identify determinant variables on 800-m running performance in young male athletes derived from field tests and biological maturity. METHODS: A total of 89 athletes, aged between 13 and 15 years old, performed a 800-m running trial and a battery of tests which involved anthropometric measurements, a running anaerobic test (RAST), a flexibility test (sit-and-reach), a counter movement jump test and progressive test for aerobic fitness evaluation...
May 5, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28479931/cardiorespiratory-fitness-and-aerobic-performance-adaptations-to-a-4-week-sprint-interval-training-in-young-healthy-untrained-females
#9
Mykolas Kavaliauskas, Thomas P Steer, John A Babraj
PURPOSE: The aim of this study was to test the effects of sprint interval training (SIT) on cardiorespiratory fitness and aerobic performance measures in young females. METHODS: Eight healthy, untrained females (age 21 ± 1 years; height 165 ± 5 cm; body mass 63 ± 6 kg) completed cycling peak oxygen uptake ([Formula: see text] peak), 10-km cycling time trial (TT) and critical power (CP) tests pre- and post-SIT. SIT protocol included 4 × 30-s "all-out" cycling efforts against 7 % body mass interspersed with 4 min of active recovery performed twice per week for 4 weeks (eight sessions in total)...
2017: Sport Sciences for Health
https://www.readbyqxmd.com/read/28475386/achieving-blood-pressure-targets-for-prolonged-cardiovascular-health-a-historical-perspective
#10
Steven G Chrysant
Hypertension is a major risk factor for coronary artery disease (CAD), stroke, heart failure, and chronic kidney disease (CKD), and its successful control leads to a decrease or prevention of these complications. Areas covered: Over the years the Joint National Committees and the American Heart Association have issued guidelines regarding the treatment of hypertension. Those of 2003 and 2007 respectively, have recommended reduction of blood pressure (BP) to < 140/90 mmHg for uncomplicated hypertension and to < 130/80 mmHg for hypertensive patients with diabetes mellitus, CKD, or CAD...
May 5, 2017: Expert Review of Cardiovascular Therapy
https://www.readbyqxmd.com/read/28474871/effects-of-hydrogen-rich-water-on-prolonged-intermittent-exercise
#11
Alessandro DA Ponte, Nicola Giovanelli, Daniele Nigris, Stefano Lazzer
BACKGROUND: Recent studies showed a positive effect of Hydrogen Rich Water (HRW) intake on acid-basic homeostasis at rest. We investigated 2-weeks of HRW intake on repeated sprint performance and acid-base status during prolonged intermittent cycling exercise. METHODS: In a cross over single-blind protocol, eight trained male cyclists (age [mean ± SD] 41±7 years, body mass 72.3±4.4 kg, height 1.77±0.04 m, maximal oxygen uptake [V̇ O2max] 52.6±4.4 ml·kg-1·min-1) were provided daily with 2 liters of placebo normal water (PLA, pH 7...
April 26, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28469760/reliability-and-validity-of-a-new-test-of-agility-and-skill-for-female-amateur-soccer-players
#12
Mehmet Kutlu, Hakan Yapici, Abdullah Yilmaz
The aim of this study was to evaluate the Agility and Skill Test, which had been recently developed to assess agility and skill in female athletes. Following a 10 min warm-up, two trials to test the reliability and validity of the test were conducted one week apart. Measurements were collected to compare soccer players' physical performance in a 20 m sprint, a T-Drill test, the Illinois Agility Run Test, change-of-direction and acceleration, as well as agility and skill. All tests were completed following the same order...
February 2017: Journal of Human Kinetics
https://www.readbyqxmd.com/read/28460405/validity-and-reliability-of-the-garmin-vector-power-meter-in-laboratory-and-field-cycling
#13
Alfred Nimmerichter, Lukas Schnitzer, Bernhard Prinz, Dieter Simon, Klaus Wirth
To assess the validity and reliability of the Garmin Vector against the SRM power meter, 6 cyclists completed 3 continuous trials at power outputs from 100-300 W at 50-90 rev·min(-1) and a 5-min time trial in laboratory and field conditions. In field conditions only, a 30-s sprint was performed. Data were compared with paired samples t-tests, with the 95% limits of agreement (LoA) and the typical error. Reliability was calculated as the coefficient of variation (CV). There was no significant difference between the devices in power output in laboratory (p=0...
May 1, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/28435687/an-evaluation-of-low-volume-high-intensity-intermittent-training-hiit-for-health-risk-reduction-in-overweight-and-obese-men
#14
Benjamin M Kelly, Soteris Xenophontos, James A King, Myra A Nimmo
ᅟ: Both sprint interval training (SIT) and high-intensity intermittent training (HIIT) have been described as time-efficient strategies for inducing favourable metabolic and cardiorespiratory adaptations in healthy and diseased participants. BACKGROUND: To date, little attention has been given to profiling the potential health benefits of HIIT or modified HIIT training within overweight and obese cohorts with particular focus on inflammation. Within this pilot trial, we tested the hypothesis that 6 sessions of HIIT performed over 2 weeks with 1-2 days' rest would improve aerobic capacity, glucose metabolism and inflammatory profile in an overweight and obese male cohort...
2017: BMC Obesity
https://www.readbyqxmd.com/read/28419027/athletes-intending-to-use-sports-supplements-are-more-likely-to-respond-to-a-placebo
#15
Philip Hurst, Abby Foad, Damian Coleman, Chris Beedie
PURPOSE: We investigated associations between athletes' use of sport supplements and their responsiveness to placebo and nocebo interventions. METHODS: Participants (n=627) reported their intention to use, and actual use of, sport supplements. They then completed a 5x20m repeat sprint protocol in the baseline condition, prior to being randomized to one of three treatments. Participants in the positive-belief treatment were administered an inert capsule described as a potent supplement which would improve sprint performance...
April 18, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28410999/impact-of-time-and-work-rest-ratio-matched-sprint-interval-training-programmes-on-performance-a-randomised-controlled-trial
#16
Molly C Lloyd Jones, Martyn G Morris, John R Jakeman
OBJECTIVES: The aim of this study was to examine the effects of a short training intervention using two repeated sprint protocols matched for total sprint duration and work:rest ratio. DESIGN: Randomised-controlled trial. METHODS: Thirty physically active males were randomly allocated to one of two sprint training groups: a 6s group, a 30s group or a non-exercising control. The training groups were matched for work:rest ratio and total sprint time per session, and completed 6 training sessions over a 2-week period...
March 31, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28387540/n-3-fatty-acid-supplementation-during-4-weeks-of-training-leads-to-improved-anaerobic-endurance-capacity-but-not-maximal-strength-speed-or-power-in-soccer-players
#17
Leyre Gravina, Frankie F Brown, Lee Alexander, James Dick, Gordon Bell, Oliver C Witard, Stuart D R Galloway
Omega-3 fatty acid (n-3 FA) supplementation could promote adaptation to soccer-specific training. We examined the impact of a 4 wk period of n-3 FA supplementation during training on adaptations in 1RM knee extensor strength, 20m sprint speed, vertical jump power, and anaerobic endurance capacity (Yo-Yo test) in competitive soccer players. Twenty six soccer players were randomly assigned to one of two groups: n-3 FA supplementation (n-3 FA; n=13) or placebo (n=13). Both groups performed two experimental trial days...
April 7, 2017: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/28379172/very-low-volume-sprint-interval-exercise-suppresses-subjective-appetite-lowers-acylated-ghrelin-and-elevates-glp-1-in-overweight-individuals-a-pilot-study
#18
Adrian Holliday, Andrew K Blannin
High-intensity exercise has been shown to elicit a transient suppression of appetite and create a more anorexigenic profile of appetite-associated hormones. It is yet to be fully elucidated whether such a response is observed following very low-volume, intermittent exercise at supramaximal intensity in those who are overweight. Eight overweight individuals (BMI 27.7 ± 1.7 kg·m²) completed resting (REST) and exercise (EX) trials in a counterbalanced order. EX consisted of 4 × 30 s "flat-out" cycling on an ergometer (adapted Wingate test)...
April 5, 2017: Nutrients
https://www.readbyqxmd.com/read/28373269/personalizing-the-intensity-of-blood-pressure-control-modeling-the-heterogeneity-of-risks-and-benefits-from-sprint-systolic-blood-pressure-intervention-trial
#19
Krishna K Patel, Suzanne V Arnold, Paul S Chan, Yuanyuan Tang, Yashashwi Pokharel, Philip G Jones, John A Spertus
BACKGROUND: In SPRINT (Systolic Blood Pressure Intervention Trial), patients with hypertension and high cardiovascular risk treated with intensive blood pressure (BP) control (<120 mm Hg) had fewer major adverse cardiovascular events (MACE) and deaths but higher rates of treatment-related serious adverse events (SAE) than patients randomized to standard BP control (<140 mm Hg). However, the degree of benefit or harm for an individual patient could vary because of heterogeneity in treatment effect...
April 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28365055/precision-medicine-for-hypertension-management-in-chronic-kidney-disease-relevance-of-sprint-for-therapeutic-targets-in-nondiabetic-renal-disease
#20
REVIEW
Marcel Ruzicka, Kevin D Burns, Swapnil Hiremath
In this review we evaluate the literature to determine if lower blood pressure (BP) targets are beneficial for patients with nondiabetic chronic kidney disease (CKD). Modification of Diet in Renal Disease (MDRD), African American Study of Kidney Disease and Hypertension (AASK), and Ramipril Efficacy in Nephropathy-2 (REIN-2), designed to assess the benefit of lower BP on progression of nondiabetic CKD, generally came to the same negative conclusion. They were not designed and powered to assess an effect of lower BP on cardiovascular outcomes...
May 2017: Canadian Journal of Cardiology
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