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https://www.readbyqxmd.com/read/28728007/direct-immune-detection-of-cortisol-by-chemiresistor-graphene-oxide-sensor
#1
Yo-Han Kim, Kyungmin Lee, Hunsang Jung, Hee Kyung Kang, Jihoon Jo, In-Kyu Park, Hyun Ho Lee
In this study, a biosensor to detect a stress biomarker of cortisol using cortisol monoclonal antibody (c-Mab) covalently immobilized on reduced graphene oxide (rGO) channel as electrical sensing element was demonstrated. Highly specific immune-recognition between the c-Mab and the cortisol was identified and characterized on a basis of resistance change at the rGO channel based chemiresistor sensor achieving the limit of detection of 10pg/mL (27.6 pM). In addition, cortisol concentrations of real human salivary sample and buffer solution of rat adrenal gland acute slices, which could secret the cortisol induced by adrenocorticotropic hormone (ACTH), were directly measured by the chemiresistor corresponding to the specific sensing of the cortisol...
July 11, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28699486/stress-depression-resilience-and-ageing-a-role-for-the-lpa-lpa1-pathway
#2
Román D Moreno-Fernández, Sara Tabbai, Estela Castilla-Ortega, Margarita Pérez-Martín, Guillermo Estivill-Torrús, Fernando Rodríguez de Fonseca, Luis J Santín, Carmen Pedraza
BACKGROUND: Chronic stress affects health and the quality of life, with its effects being particularly relevant in ageing due to the psychobiological characteristics of this population. However, while some people develop psychiatric disorders, especially depression, others seem very capable of dealing with adversity. There is no doubt that along with the identification of neurobiological mechanisms involved in developing depression, discovering which factors are involved in positive adaptation under circumstances of extreme difficulty will be crucial for promoting resilience...
July 10, 2017: Current Neuropharmacology
https://www.readbyqxmd.com/read/28690872/physiological-and-lipid-profile-response-to-acute-exercise-at-different-intensities-in-individuals-with-spinal-cord-injury
#3
Eduardo S Alves, Ronaldo Vt Santos, Francieli S Ruiz, Fabio S Lira, Alexandre A Almeida, Giscard Lima, Thatiana Cs Goni, Lila Oyama, Kate M Edwards, Sergio Tufik, Marco Túlio De Mello
STUDY DESIGN: Experimental and cross-sectional study. OBJECTIVE: To assess the immediate effect of exercise on heart rate (HR), oxygen uptake (VO2), pulmonary ventilation (PV), oxygen pulse (OP), glucose and lipids of wheelchair basketball players with spinal cord injury (SCI). SETTING: Center of Studies in Psychobiology and Exercise-São Paulo, Brazil. METHODS: In all, nine wheelchair basketball players with SCI and nine able-bodied controls (C) performed three exercise sessions at different intensities: ventilatory threshold 1 (VT1), 15% below VT1 and 15% above VT1 with a duration of ~24-34 min...
2017: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/28682230/-genetics-and-epigenetics-of-suicidal-behaviors
#4
Emilie Olié, Philippe Courtet
With more than 10 000 deaths each year in France, suicide is a major public health problem. Despite many known risk factors, suicide prediction remains extremely difficult in daily clinical practice. The identification of biomarkers, including genetic and epigenetic factors, is needed in suicidology in order to better understand pathophysiology of such behaviors and to improve the screening of individuals at high suicidal risk. Numerous studies have reported candidate genes involved in serotonergic system, HPA axis and neurotrophic system...
2017: Biologie Aujourd'hui
https://www.readbyqxmd.com/read/28681106/proactive-and-reactive-aggression-subgroups-in-typically-developing-children-the-role-of-executive-functioning-psychophysiology-and-psychopathy
#5
Nicholas D Thomson, Luna C M Centifanti
This study aimed to assess whether groups of aggressive children differed on psychopathic traits, and neuropsychological and neurobiological measures of prefrontal functioning consistent with the objectives of their aggression-reactive or proactive. Including 110 typically developing children (9-11 years), a latent class analysis identified a low aggression group, a high reactive aggression group, and a mixed (high reactive and proactive) aggression group. Results show high callous-unemotional traits and low resting respiratory sinus arrhythmia increased the likelihood of children being in the mixed aggression group, when compared to the reactive and low aggression groups...
July 5, 2017: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/28661257/recreational-3-4-methylenedioxymethamphetamine-or-ecstasy-current-perspective-and-future-research-prospects
#6
Andrew C Parrott, Luke A Downey, Carl A Roberts, Cathy Montgomery, Raimondo Bruno, Helen C Fox
AIMS: The purpose of this article is to debate current understandings about the psychobiological effects of recreational 3,4-methylenedioxymethamphetamine (MDMA or 'ecstasy'), and recommend theoretically-driven topics for future research. METHODS: Recent empirical findings, especially those from novel topic areas were reviewed. Potential causes for the high variance often found in group findings were also examined. RESULTS AND CONCLUSIONS: The first empirical reports into psychobiological and psychiatric aspects from the early 1990s concluded that regular users demonstrated some selective psychobiological deficits, for instance worse declarative memory, or heightened depression...
June 1, 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/28604231/the-psychometrics-of-the-european-portuguese-version-of-the-temperament-and-character-inventory-revised
#7
Paulo A S Moreira, Claude Robert Cloninger, Maria José Rocha, João Tiago Oliveira, Noémia Ferreira, Daniel Maffasioli Gonçalves, Sándor Rózsa
Cloninger's psychobiological model of personality integrates contributions from behavioral genetics, neurobiology, and psychology in the description of the human personality. The temperament and character inventory (TCI) is its assessment instrument. The Brazilian Portuguese version of the TCI has shown good psychometric properties. However, Portuguese spoken in Brazil presents marked and substantial differences to that spoken in Portugal, and no study has yet described the psychometrics of the European Portuguese version...
January 1, 2017: Psychological Reports
https://www.readbyqxmd.com/read/28595479/psychobiology-of-cumulative-trauma-hair-cortisol-as-a-risk-marker-for-stress-exposure-in-women
#8
Matthew C Morris, James L Abelson, Alyssa S Mielock, Uma Rao
Childhood trauma (CT) is associated with long-lasting alterations of the hypothalamic-pituitary-adrenal (HPA) axis and elevated risk for stress exposure in adulthood. Although HPA alterations are present in the early aftermath of trauma, it remains unclear how initial HPA activity is associated with subsequent stress exposure and whether CT exposure influences the strength and direction of this association. The present study examined prospective associations between hair cortisol content (HCC) and stress exposure from baseline to 3-month follow-up in young adult women with recent (i...
June 29, 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/28557820/features-of-resting-state-eeg-theta-coherence-in-somatic-symptom-disorder-compared-to-major-depressive-disorder-a-pilot-study
#9
Jaeyoung Ahn, Doug Hyun Han, Ji Sun Hong, Kyoung Joon Min, Young Sik Lee, Bong-Jin Hahm, Sun Mi Kim
OBJECTIVE: Somatic symptom disorder (SSD) often co-occurs with major depressive disorder (MDD). Both conditions share common psychobiological and biobehavioral characteristics, but little is known about differential patterns in brain function. In this study, we compared resting-state functional brain connectivity between SSD and MDD using quantitative electroencephalography (QEEG). METHODS: Fifteen patients with SSD (SSD group), 15 patients with MDD (MDD group), and 15 healthy volunteers (HC group) participated in this study...
May 27, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28557129/recreational-stimulants-herbal-and-spice-cannabis-the-core-psychobiological-processes-that-underlie-their-damaging-effects
#10
Andrew C Parrott, Amie C Hayley, Luke A Downey
AIMS: Recreational drugs are taken for their positive mood effects, yet their regular usage damages well-being. The psychobiological mechanisms underlying these damaging effects will be debated. METHODS: The empirical literature on recreational cannabinoids and stimulant drugs is reviewed. A theoretical explanation for how they cause similar types of damage is outlined. RESULTS: All psychoactive drugs cause moods and psychological states to fluctuate...
May 30, 2017: Human Psychopharmacology
https://www.readbyqxmd.com/read/28551941/-the-placebo-effect-neurobiological-aspects
#11
REVIEW
Asael Lubotzky, Adi Aran
Any medical treatment, whether it be medication, behavioral therapy or medical procedure, can affect the patient in a very complex way. Each of these forms of medical treatment have both psychobiological and physiological effects on the patient, with interactions between those levels. When considering the specific efficacy of a new treatment, there is therefore a need to neutralize the psychobiological effect by comparing the effect of the treatment to the effect of a placebo - a treatment involving similar characteristics which does not produce that physiological effect...
March 2017: Harefuah
https://www.readbyqxmd.com/read/28544861/social-buffering-of-stress-in-development-a-career-perspective
#12
Megan R Gunnar
This review provides a broad overview of my research group's work on social buffering in human development in the context of the field. Much of the focus is on social buffering of the hypothalamic-pituitary-adrenocortical (HPA) system, one of the two major arms of the mammalian stress system. This focus reflects the centrality of the HPA system in research on social buffering in the fields of developmental psychobiology and developmental science. However, buffering of the cardiovascular and autonomic nervous system is also discussed...
May 2017: Perspectives on Psychological Science: a Journal of the Association for Psychological Science
https://www.readbyqxmd.com/read/28540348/psychobiological-responses-to-critically-evaluated-multitasking
#13
Mark A Wetherell, Olivia Craw, Kenny Smith, Michael A Smith
In order to understand psychobiological responses to stress it is necessary to observe how people react to controlled stressors. A range of stressors exist for this purpose; however, laboratory stressors that are representative of real life situations provide more ecologically valid opportunities for assessing stress responding. The current study assessed psychobiological responses to an ecologically valid laboratory stressor involving multitasking and critical evaluation. The stressor elicited significant increases in psychological and cardiovascular stress reactivity; however, no cortisol reactivity was observed...
December 2017: Neurobiology of Stress
https://www.readbyqxmd.com/read/28527679/salivary-steroid-response-and-competitive-anxiety-in-elite-basketball-players-effect-of-opponent-level
#14
Ademir F S Arruda, Marcelo S Aoki, Ana Carolina Paludo, Alexandre Moreira
This study examined the effect of playing matches against different opponent teams (hard match; HM, medium match; MM, and easy match; EM) on pre-match testosterone concentration (T), pre-to-post match cortisol (C) concentration, and pre-competitive anxiety (CSAI-2 questionnaire) in 20 elite male basketball players. One training session (TS) was also assessed (control condition). Saliva steroids were determined by ELISA. The pre-T concentration was significantly lower for the TS (163±54pmolL(-1)), compared to the three official matches (EM: 208±82pmolL(-1), MM: 213±57pmolL(-1), and HM: 218±37pmolL(-1)) (p<0...
August 1, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28513305/do-sitting-standing-or-treadmill-desks-impact-psychobiological-indicators-of-work-productivity
#15
Nicholas D Gilson, Caitlin Hall, Angela Renton, Norman Ng, William von Hippel
BACKGROUND: This pilot study investigated links between psychobiological indicators of work productivity, prolonged desk sitting, and conditions whereby office workers were able to interrupt sitting using a sit-stand or treadmill desk. METHODS: Twenty participants visited our laboratory and completed their own desk work in counterbalanced sit-only, sit-stand (Varidesk Pro Plus 48(TM)) and sit-walk conditions (Infiniti TR1200-DTS(TM)). Steady state visually evoked potentials (SSVEPs) calculated from electroencephalography recordings during a set task at the end of the workday assessed attentional resource...
May 17, 2017: Journal of Physical Activity & Health
https://www.readbyqxmd.com/read/28507528/cognitive-impairments-in-occupational-burnout-error-processing-and-its-indices-of-reactive-and-proactive-control
#16
Krystyna Golonka, Justyna Mojsa-Kaja, Magda Gawlowska, Katarzyna Popiel
The presented study refers to cognitive aspects of burnout as the effects of long-term work-related stress. The purpose of the study was to investigate electrophysiological correlates of burnout to explain the mechanisms of the core burnout symptoms: exhaustion and depersonalization/cynicism. The analyzed error-related electrophysiological markers shed light on impaired cognitive mechanisms and the specific changes in information-processing in burnout. In the EEG study design (N = 80), two components of error-related potential (ERP), error-related negativity (ERN), and error positivity (Pe), were analyzed...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28498273/effects-of-preoperative-psychological-interventions-on-catecholamineand-cortisol-levels-after-surgery-in-coronary-artery-bypass-graft-patients-the-randomized-controlled-psy-heart-trial
#17
Stefan Salzmann, Frank Euteneuer, Johannes A C Laferton, Charlotte J Auer, Meike C Shedden-Mora, Manfred Schedlowski, Rainer Moosdorf, Winfried Rief
OBJECTIVE: To examine whether preoperative psychological interventions targeting patients' expectations are capable of influencing the biological stress response after coronary artery bypass graft (CABG) surgery and could thus improve recovery after heart surgery. METHODS: Randomized controlled trial with assessments 10 days before surgery, post-psychological intervention (day of hospital admission, but before surgery), postoperative (6-8 days later) and at follow-up (6 months after surgery)...
May 12, 2017: Psychosomatic Medicine
https://www.readbyqxmd.com/read/28448425/vulnerability-to-psychopathology-and-dimensions-of-personality-in-patients-with-fibromyalgia
#18
Alba Garcia-Fontanals, Mariona Portell, Susanna García-Blanco, Violant Poca-Dias, Ferran García-Fructuoso, Marina López-Ruiz, Teresa Gutiérrez-Rosado, Montserrat Gomà-I-Freixanet, Joan Deus
OBJECTIVE: Fibromyalgia (FM) patients may present psychopathology and some characteristic personality traits that may affect their adaptation to the disease. This paper aims to study the relationship between personality dimensions according to the psychobiological model of Cloninger and the presence of psychopathology. METHOD: The study sample consisted of 42 patients with FM and 38 healthy controls. The assessment instruments administered were the Temperament and Character Inventory (TCI-R) and the Millon Clinical Multiaxial Inventory (MCMI-III)...
April 26, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28438635/testosterone-and-cortisol-responses-in-male-soccer-players-the-effect-of-home-and-away-venues
#19
Melissa Fothergill, Sandy Wolfson, Nick Neave
The present studies examined the influence of playing venue on psychobiological responses in male soccer players. Many studies have demonstrated the existence of a home advantage, wherein teams perform better at home than away. A recent focus has attempted to explain this advantage from a psychobiological perspective, with studies showing hormonal differences with regard to venue, game outcome, dominance and perceived stress. Two studies investigated testosterone and cortisol responses in relation to home and away venues...
April 21, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28435680/adiposity-cvd-risk-factors-and-testosterone-variation-by-partnering-status-and-residence-with-children-in-us-men
#20
Lee T Gettler, Mallika S Sarma, Rieti G Gengo, Rahul C Oka, James J McKenna
Background and objectives: In many settings, partnered, invested fathers have lower testosterone than single men or fathers who are not involved in caregiving. Reduced testosterone has been identified as a risk factor for multiple chronic diseases, and men's health also commonly varies by life history status. There have been few tests of whether variation in testosterone based on partnering and parenting has implications for men's health. Methodology: We analysed data from a US population-representative sample (NHANES) of young-to-middle aged US men (n = 875; mean age: 29...
2017: Evolution, Medicine, and Public Health
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