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https://www.readbyqxmd.com/read/29040871/gray-matter-networks-and-clinical-progression-in-subjects-with-predementia-alzheimer-s-disease
#1
Betty M Tijms, Mara Ten Kate, Alida A Gouw, Andreas Borta, Sander Verfaillie, Charlotte E Teunissen, Philip Scheltens, Frederik Barkhof, Wiesje M van der Flier
We studied whether gray matter network parameters are associated with rate of clinical progression in nondemented subjects who have abnormal amyloid markers in the cerebrospinal fluid (CSF), that is, predementia Alzheimer's disease. Nondemented subjects (62 with subjective cognitive decline; 160 with mild cognitive impairment (MCI); age = 68 ± 8 years; Mini-Mental State Examination (MMSE) = 28 ± 2.4) were selected from the Amsterdam Dementia Cohort when they had abnormal amyloid in CSF (<640 pg/mL)...
September 20, 2017: Neurobiology of Aging
https://www.readbyqxmd.com/read/29036206/risk-characterization-of-hospitalizations-for-mental-illness-and-or-behavioral-disorders-with-concurrent-heat-related-illness
#2
Michael T Schmeltz, Janet L Gamble
BACKGROUND: Many studies have found significant associations between high ambient temperatures and increases in heat-related morbidity and mortality. Several studies have demonstrated that increases in heat-related hospitalizations are elevated among individuals with diagnosed mental illnesses and/or behavioral disorders (MBD). However, there are a limited number of studies regarding risk factors associated with specific mental illnesses that contribute, at least in part, to heat-related illnesses (HRI) in the United States...
2017: PloS One
https://www.readbyqxmd.com/read/29032408/the-natural-history-of-depressive-symptoms-in-patients-with-incident-parkinson-s-disease-a-prospective-cohort-study
#3
Jan Petter Larsen, Ingvild Dalen, Kenn Freddy Pedersen, Ole-Bjørn Tysnes
Depression is common in patients with Parkinson disease and causes suffering and increased caregiver burden. A better understanding of depressive symptoms in Parkinson disease, their progression, and risk factors may, therefore, benefit management of these patients. The present study included 187 drug-naïve patients with incident PD and 166 controls from the population-based Norwegian ParkWest project. Depressive symptoms were examined with the Montgomery and Aasberg Depression Rating Scale (MADRS) at time of diagnosis and inclusion in the study and after 1, 3, 5, and 7 years of follow-up...
October 14, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/29027060/the-mental-health-of-adolescents-residing-in-court-ordered-foster-care-findings-from-a-population-survey
#4
Michael Tarren-Sweeney
The mental health of a representative sample of 230 adolescents residing in foster care in New South Wales, Australia, was estimated in a state-wide epidemiological survey from carer-report responses on the Child Behavior Checklist (CBCL) and the Assessment Checklist for Adolescents (ACA). Rates of CBCL total problems, externalizing and internalizing scores above the borderline range cut-points were 49, 44 and 29% respectively, representing a relative risk of 3.8, 3.7 and 2.7 respectively in comparison to Australian children at large...
October 12, 2017: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/29024062/why-run-the-risk-motivation-for-offences-by-patients-with-substance-use-and-antisocial-personality-disorders-which-they-rated-as-most-risky-to-their-own-well-being
#5
Birgitte Thylstrup, Morten Hesse
BACKGROUND: Understanding motives for offending is important for the development and delivery of effective interventions. AIMS: To explore associations between variables with motivational implications and the offence committed in the past year rated by people with antisocial personality disorder and substance use disorder as putting them and their status at most risk. METHODS: Participants were 127 outpatients from a sample recruited for a pragmatic randomised controlled trial of an intervention for adults attending substance abuse treatment clinics in 13 municipalities in Denmark...
October 10, 2017: Criminal Behaviour and Mental Health: CBMH
https://www.readbyqxmd.com/read/29023134/a-systematic-review-of-correlates-of-depression-among-older-chinese-and-korean-immigrants-what-we-know-and-do-not-know
#6
Man Guo, Meredith Stensland
OBJECTIVES: Guided by the stress and coping theory, this study provides a systematic review of existing research on acculutration, family support, and social support related correlates of depression among older Chinese and Korean immigrants in the United States. METHOD: A comprehensive literature search was conducted in CINAHL Plus, Abstracts in Social Gerontology, AgeLine, Social Work Abstracts, PubMed, PsychINFO, and Social Science Citation Index databases to identify relevant articles that presented multivariate analysis results...
October 12, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/29020419/cortical-gaba-in-subjects-at-ultra-high-risk-of-psychosis-relationship-to-negative-prodromal-symptoms
#7
Gemma Modinos, Fatma Simsek, Jamie Horder, Matthijs Bossong, Ilaria Bonoldi, Matilda Azis, Jesus Perez, Matthew Broome, David J Lythgoe, James M Stone, Oliver D Howes, Declan G Murphy, Anthony A Grace, Paul Allen, Philip McGuire
Background: Whilst robust preclinical and postmortem evidence suggests that altered GABAergic function is central to the development of psychosis, little is known about whether it is altered in subjects at ultra-high risk of psychosis, or its relationship to prodromal symptoms. Methods: Twenty-one anti-psychotic naïve UHR individuals and 20 healthy volunteers underwent proton magnetic resonance imaging at 3T. GABA levels were obtained from the medial prefrontal cortex (MPFC) using MEGA-PRESS, and expressed as peak-area ratios relative to the synchronously-acquired creatine signal...
August 19, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29018022/higher-adiposity-is-associated-with-slower-cognitive-decline-in-hypertensive-patients-secondary-analysis-of-the-china-stroke-primary-prevention-trial
#8
Jun Zhang, Genfu Tang, Haiqun Xie, Binyan Wang, Mingli He, Jia Fu, Xiuli Shi, Chengguo Zhang, Yong Huo, Xiping Xu, Kai Wang
BACKGROUND: Obesity is a risk factor for many diseases. However, the potential association between adiposity and cognitive decline in hypertensive patients is inconclusive. We performed a secondary data analysis of the CSPPT (China Stroke Primary Prevention Trial) to examine whether adiposity is correlated with longitudinal cognitive performance in hypertensive adults. METHODS AND RESULTS: The analysis included 16 791 patients in the CSPPT who received at least 2 cognitive assessments by the Mini-Mental State Examination (MMSE) during the follow-up (median, 4...
October 10, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29017063/european-status-and-perspectives-on-early-detection-and-intervention-in-at-risk-mental-state-and-first-episode-psychosis-viewpoint-from-the-epa-section-for-prevention-of-mental-disorders
#9
EDITORIAL
N P Maric, A Raballo, M Rojnic Kuzman, S Andric Petrovic, J Klosterkötter, A Riecher-Rössler
No abstract text is available yet for this article.
September 8, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/29016364/burnout-and-psychological-distress-among-pediatric-critical-care-physicians-in-the-united-states
#10
Asha N Shenoi, Meena Kalyanaraman, Aravind Pillai, Preethi S Raghava, Scottie Day
OBJECTIVES: To estimate the prevalence of physician burnout, psychological distress, and its association with selected personal and practice characteristics among pediatric critical care physicians and to evaluate the relationship between burnout and psychological distress. DESIGN: Cross-sectional, online survey. SETTING: Pediatric critical care practices in the United States. SUBJECTS: Pediatric critical care physicians...
October 7, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28984092/patterns-of-changes-in-functional-and-neurocognitive-status-in-elderly-patients-after-transcatheter-vs-surgical-aortic-valve-replacements
#11
Marta Załęska-Kocięcka, Anna Skrobisz, Sebastian Woźniak, Lidia Greszata, Maciej Dąbrowski, Maciej Grabowski, Katarzyna Piotrowska, Anna Konopka, Marek Banaszewski, Anna Mierzynska
BACKGROUND: Replacement of severely stenotic aortic valve may influence cognitive and physical functioning. The aim of this study was to compare cognitive and functional status after surgical (SAVR) vs transcatheter aortic valve replacements (TAVR) in the elderly with severe aortic stenosis (AS). METHODS: It was a prospective observational study with over 6 months of follow-up. Eighty ≥70-year-old patients with AS underwent TAVR (n=40) or SAVR (n=40). Mini Mental State Exam (MMSE), Activities Daily Living (ADL) score and Instrumental Activities Daily Living (IADL) score were used to assess the cognitive status, fundamental functioning and complex independent living skills, respectively...
October 4, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/28984077/broad-clinical-high-risk-mental-state-charms-methodology-of-a-cohort-study-validating-criteria-for-pluripotent-risk
#12
Jessica A Hartmann, Barnaby Nelson, Rachael Spooner, G Paul Amminger, Andrew Chanen, Christopher G Davey, Meredith McHugh, Aswin Ratheesh, Devi Treen, Hok Pan Yuen, Patrick D McGorry
AIM: The development of the ultra-high risk (UHR) criteria for psychosis created a new paradigm for the prevention research in psychiatry. Since (1) prevention research faces the challenge of achieving adequate statistical power when focusing on single low-incidence syndromes and (2) early clinical phenotypes are overlapping and non-specific, this study broadens the UHR state beyond psychosis as an outcome. The CHARMS (clinical high at-risk mental state) study aims to prospectively validate a set of trans-diagnostic criteria to identify help-seeking young people at risk of developing a range of serious mental illnesses...
October 5, 2017: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/28983443/rowers-self-reported-behaviors-attitudes-and-safety-concerns-related-to-exercise-training-and-competition-during-pregnancy
#13
Ashley Franklin, Joanna Mishtal, Teresa Johnson, Judith Simms-Cendan
Background The American College of Obstetrics and Gynecology notes that pregnant athletes require more supervision due to their involvement in strenuous training schedules throughout pregnancy. Currently, rowing is not mentioned in the guidelines despite its increasing popularity, high cardiovascular demands, and risk for abdominal trauma. Methods This study aimed to elicit information from competitive female rowers regarding exercise, training, and competition during pregnancy. We administered a survey consisting of 122 items to female Masters rowers in the United States, aged 21 to 49 years, from June to December 2013...
August 1, 2017: Curēus
https://www.readbyqxmd.com/read/28983317/genetic-analysis-of-mitochondrial-ribosomal-proteins-and-cognitive-aging-in-postmenopausal-women
#14
Khyobeni Mozhui, Beverly M Snively, Stephen R Rapp, Robert B Wallace, Robert W Williams, Karen C Johnson
Genes encoding mitochondrial ribosomal proteins (MRPs) have been linked to aging and longevity in model organisms (i.e., mice, Caenorhabditis elegans). Here we evaluated if the MRPs have conserved effects on aging traits in humans. We utilized data from 4,504 participants of the Women's Health Initiative Memory Study (WHIMS) who had both longitudinal cognitive data and genetic data. Two aging phenotypes were considered: (1) gross lifespan (time to all-cause mortality), and (2) cognitive aging (longitudinal rate of change in modified mini-mental state scores)...
2017: Frontiers in Genetics
https://www.readbyqxmd.com/read/28977360/cognitive-function-and-changes-in-cognitive-function-as-predictors-of-incident-cardiovascular-disease-the-women-s-health-initiative-memory-study
#15
Xiaoyan Leng, Mark A Espeland, JoAnn E Manson, Marcia L Stefanick, Emily W Gower, Kathleen M Hayden, Marian C Limacher, Leslie Vaughan, Jennifer Robinson, Robert Wallace, Sylvia Wassertheil-Smoller, Kristine Yaffe, Sally A Shumaker
Background: Cognitive impairment and decline may signal the increased risk of incident cardiovascular disease (CVD). We examined associations of global cognitive function, as measured by the Modified Mini-Mental State Examination (3MS) and changes in 3MS over time, with incident CVD, individual CVD outcomes, CVD death, and all-cause mortality. Methods: A total of 5,596 women (≥ 60) from the Women's Health Initiative Memory Study free of CVD at baseline were followed for an average of 7...
July 25, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28975609/healthcare-associated-meningitis-or-ventriculitis-in-older-adults
#16
Chanunya Srihawan, Onaizah Habib, Lucrecia Salazar, Rodrigo Hasbun
BACKGROUND/OBJECTIVES: Healthcare-associated meningitis or ventriculitis (HCAMV) is a serious and life-threatening complication of invasive neurosurgical procedures or penetrating head trauma. Older adults are at higher risk of adverse outcomes in community-acquired meningitis but studies of HCAMV are lacking. Therefore, we perform the study to define the differences in clinical outcomes between older and younger adults with HCAMV. DESIGN: Retrospective study. SETTING: A large tertiary care hospital in Houston, Texas, from July 2003 to November 2014...
October 4, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28967717/we-all-want-to-live-longer-but-not-grow-old
#17
Simona Giampaoli, Giovanni Viscogliosi, Diego Vannuzzo
Population ageing represents a "triumph" and a "challenge" for society. The increase in life expectancy corresponds to an increase of risk factors and age-associated non communicable diseases, with consequent rise in health care costs and the burden of healthcare sustainability. Aim of this analysis is to describe the prevalence of non communicable diseases, comorbidity and disability in non-institutionalized elderly population, aged 75-79 years, examined within the Osservatorio Epidemiologico Cardiovascolare/Health Examination Survey...
July 18, 2017: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/28964659/decreasing-suicide-risk-among-patients-with-prostate-cancer-implications-for-depression-erectile-dysfunction-and-suicidal-ideation-screening
#18
REVIEW
Zachary Klaassen, Karan Arora, Shenelle N Wilson, Sherita A King, Rabii Madi, Durwood E Neal, Paul Kurdyak, Girish S Kulkarni, Ronald W Lewis, Martha K Terris
OBJECTIVE: Prostate cancer is the most common malignancy among males, accounting for 19% of cancers, and the third most common cancer-related cause of death. Suicide rates in the United States have increased among males over the last decade. Further, suicide rates are higher in oncology patients, including patients with prostate cancer, compared to the general population. The objective of this article is to review the current literature and address the relationship between prostate cancer, depression, erectile dysfunction, and suicidal ideation...
September 27, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28959452/predicting-early-transition-from-sub-syndromal-presentations-to-major-mental-disorders
#19
Shane P M Cross, Jan Scott, Ian B Hickie
BACKGROUND: Transition from at-risk state to full syndromal mental disorders is underexplored for unipolar and bipolar disorders compared with psychosis. AIMS: Prospective, trans-diagnostic study of rates and predictors of early transition from sub-threshold to full syndromal mental disorder. METHOD: One-year outcome of 243 consenting youth aged 15-25 years with a sub-syndromal presentation of a potentially severe mental disorder. Survival analysis and odds ratio (OR) for predictors of transition identified from baseline clinical and demographic ratings...
September 2017: BJPsych Open
https://www.readbyqxmd.com/read/28953848/physical-health-assessment-and-medicines-reconciliation-on-admission-to-an-acute-mental-health-unit-a-quality-improvement-project
#20
Arani Vivekanantham, Abdur-Raoof Sheikh, Hisham Omer, Nicholas Bescoby-Chambers
Individuals with mental health disorders are at greater risk of physical health problems. Medicines reconciliation reduces medication errors on admission. The aim of this project was to improve compliance with the completion of physical health assessments and medicines reconciliation forms by using a set standard stating that all patients must have the above completed at the point of admission to an acute mental health unit. The notes for all inpatients were reviewed for evidence of completed physical assessments and medicines reconciliation forms...
September 2017: Psychiatria Danubina
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