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at-risk mental state

Joyce Y Lee, Heather A Knauer, Shawna J Lee, Mark P MacEachern, Craig F Garfield
CONTEXT: Fathers contribute to their children's health starting at the beginning of life. Few parent education programs include fathers. Among those that do, there is little effort to report program effects on father outcomes. OBJECTIVE: In this systematic review, we examined father-inclusive perinatal parent education programs in the United States as they relate to a range of father outcomes. DATA SOURCES: The databases searched were PubMed, Cumulative Index to Nursing and Allied Health Literature, Embase, Ovid Medline, Cochrane Central Register of Controlled Trials, and PsycINFO...
June 14, 2018: Pediatrics
Francisco Caamano-Isorna, Amy Adkins, Lucía Moure-Rodríguez, Abigail H Conley, Danielle Dick
The aim of this study was to determine the incidence of sexual and physical assault among university students and its association with alcohol use. The research is part of a wider cohort study (Spit for ScienceTM ) at a large public university in the United States. The follow-up data include the first two cohorts (2011, 2012; n = 5,170). The dependent variables were victim of sexual assault and victim of physical assault. The independent variables were alcohol dependence and abuse according to the Diagnostic and Statistical Manual of Mental Disorders (4th ed...
June 1, 2018: Journal of Interpersonal Violence
Xi Zhu, Douglas R Wholey
OBJECTIVE: To examine how expertise redundancy and transactive memory (TM) in interdisciplinary care teams (ICTs) are related to team performance. DATA SOURCES/STUDY SETTING: Survey and administrative data were collected from 26 interdisciplinary mental health teams. STUDY DESIGN: The study used a longitudinal, observational design. Independent variables were measured at baseline, 6, and 12 months: expertise redundancy (the extent to which team members possess highly overlapping knowledge), TM accuracy (the extent to which team members accurately recognize experts in relevant knowledge domains), and TM consensus (the extent to which team members agree on who is expert in which knowledge domain)...
June 12, 2018: Health Services Research
Esther J M de Brouwer, Remko Kockelkoren, Jules J Claus, Annemarieke de Jonghe, Mirjam I Geerlings, Thomas E F Jongsma, Willem P T M Mali, Jeroen Hendrikse, Pim A de Jong, Huiberdina L Koek
Purpose To identify risk factors for hippocampal calcifications and to investigate the association between hippocampal calcifications and cognitive function. Materials and Methods For this retrospective study, consecutive patients visiting a memory clinic at a Dutch general hospital between April 2009 and April 2015 were identified. All individuals underwent a standard diagnostic work-up including cognitive tests and brain CT. The following vascular risk factors were assessed: hypertension, diabetes mellitus, hyperlipidemia, and smoking...
June 12, 2018: Radiology
Mi-Jung Kim, Shin-Bi Oh, Juyeon Kim, Kiju Kim, Ho-Sung Ryu, Min Sun Kim, Scott Ayton, Ashley I Bush, Joo-Yong Lee, Sun Ju Chung
INTRODUCTION: While metals have been implicated in the pathophysiology of Parkinson's disease (PD), the clinical evidence is scarce. Further, the contribution of metals for the risk or clinical presentation of PD remains to be explored. METHODS: To investigate the associations between the level of metals in blood serum and PD risk or clinical presentation, including sex-related differences, we studied 325 PD patients and age- and sex-matched 304 controls. We collected clinical data of the PD patients, including age at onset, PD duration, levodopa-equivalent dose (LED), Hoehn and Yahr stage (H-Y stage), presence of motor fluctuation, levodopa-induced dyskinesia (LID), freezing of gait, hallucination, and Mini-Mental State Examination (MMSE) score...
May 28, 2018: Parkinsonism & related Disorders
Nicola Heslehurst, Heather Brown, Augustina Pemu, Hayley Coleman, Judith Rankin
BACKGROUND: Global migration is at an all-time high with implications for perinatal health. Migrant women, especially asylum seekers and refugees, represent a particularly vulnerable group. Understanding the impact on the perinatal health of women and offspring is an important prerequisite to improving care and outcomes. The aim of this systematic review was to summarise the current evidence base on perinatal health outcomes and care among women with asylum seeker or refugee status. METHODS: Twelve electronic database, reference list and citation searches (1 January 2007-July 2017) were carried out between June and July 2017...
June 12, 2018: BMC Medicine
Ernesto González-Mesa, Kamile Kabukcuoglu, Oznur Körükcü, Marta Blasco, Nadia Ibrahim, Türker Kavas
BACKGROUND: Depression is the most frequent mental disorder during pregnancy, and its prevalence is at least as high as that of postnatal depression. Differences between Western and Eastern countries may exist according to cultural and educational factors. OBJECTIVE: to determine the influence of social and cultural factors on the mood state of a multicultural sample of 514 Turkish and Spanish pregnant women at the beginning of the pregnancy. METHODS: Between October and December 2017 250 Turkish and 264 Spanish pregnant women attending their first pregnancy medical check-up between 10 and 12 weeks of pregnancy were recruited (264 in Málaga, 102 in Istanbul and 148 in Antalya)...
June 2, 2018: Journal of Affective Disorders
Mhairi McDonald, Eleni Christoforidou, Nicola Van Rijsbergen, Ruchika Gajwani, Joachim Gross, Andrew I Gumley, Stephen M Lawrie, Matthias Schwannauer, Frauke Schultze-Lutter, Peter J Uhlhaas
Introduction: Identification of participants at clinical high-risk (CHR) for the development of psychosis is an important objective of current preventive efforts in mental health research. However, the utility of using web-based screening approaches to detect CHR participants at the population level has not been investigated. Methods: We tested a web-based screening approach to identify CHR individuals. Potential participants were invited to a website via e-mail invitations, flyers, and invitation letters involving both the general population and mental health services...
June 8, 2018: Schizophrenia Bulletin
Nadja P Maric, Sanja Andric Petrovic, Andrea Raballo, Martina Rojnic-Kuzman, Joachim Klosterkötter, Anita Riecher-Rössler
AIM: Early detection/early intervention (ED/EI) programmes have been inconsistently implemented throughout Europe. We evaluated the ED/EI service distribution in European Psychiatric Association (EPA) member countries, considering indicators of socio-economic development, human and financial resources allocated in mental health (MH) as well as presence of a national branch of the Early Intervention in MH (IEPA). Contextually, we evaluated the duration of untreated psychosis (DUP) in relation to ED/EI service implementation...
June 8, 2018: Early Intervention in Psychiatry
Measha Bright, Sophie Parker, Paul French, Anthony P Morrison, Sarah Tully, Suzanne L K Stewart, Adrian Wells
AIM: The Metacognitions Questionnaire-30 (MCQ-30) has been used to assess metacognitive beliefs in a range of mental health problems. The aim of this study is to assess the validity of the MCQ-30 in people at risk for psychosis. METHODS: One hundred eighty-five participants meeting criteria for an at risk mental state completed the MCQ-30 as part of their involvement in a randomized controlled trial. Confirmatory and exploratory factor analyses were conducted to assess factor structure and construct validity...
June 7, 2018: Clinical Psychology & Psychotherapy
Pamela Scorza, Katherine Masyn, Joshua A Salomon, Theresa S Betancourt
BACKGROUND: Depression is currently the second largest contributor to non-fatal disease burden globally. For that reason, economic evaluations are increasingly being conducted using data from depression prevalence estimates to analyze return on investments for services that target mental health. Psychiatric epidemiology studies have reported large cross-national differences in the prevalence of depression. These differences may impact the cost-effectiveness assessments of mental health interventions, thereby affecting decisions regarding government and multi-lateral investment in mental health services...
2018: PloS One
Deborah M Stone, Thomas R Simon, Katherine A Fowler, Scott R Kegler, Keming Yuan, Kristin M Holland, Asha Z Ivey-Stephenson, Alex E Crosby
INTRODUCTION: Suicide rates in the United States have risen nearly 30% since 1999, and mental health conditions are one of several factors contributing to suicide. Examining state-level trends in suicide and the multiple circumstances contributing to it can inform comprehensive state suicide prevention planning. METHODS: Trends in age-adjusted suicide rates among persons aged ≥10 years, by state and sex, across six consecutive 3-year periods (1999-2016), were assessed using data from the National Vital Statistics System for 50 states and the District of Columbia...
June 8, 2018: MMWR. Morbidity and Mortality Weekly Report
John L Robinson, Edward B Lee, Sharon X Xie, Lior Rennert, EunRan Suh, Colin Bredenberg, Carrie Caswell, Vivianna M Van Deerlin, Ning Yan, Ahmed Yousef, Howard I Hurtig, Andrew Siderowf, Murray Grossman, Corey T McMillan, Bruce Miller, John E Duda, David J Irwin, David Wolk, Lauren Elman, Leo McCluskey, Alice Chen-Plotkin, Daniel Weintraub, Steven E Arnold, Johannes Brettschneider, Virginia M-Y Lee, John Q Trojanowski
Lewy bodies commonly occur in Alzheimer's disease, and Alzheimer's disease pathology is frequent in Lewy body diseases, but the burden of co-pathologies across neurodegenerative diseases is unknown. We assessed the extent of tau, amyloid-β, α-synuclein and TDP-43 proteinopathies in 766 autopsied individuals representing a broad spectrum of clinical neurodegenerative disease. We interrogated pathological Alzheimer's disease (n = 247); other tauopathies (n = 95) including Pick's disease, corticobasal disease and progressive supranuclear palsy; the synucleinopathies (n = 164) including multiple system atrophy and Lewy body disease; the TDP-43 proteinopathies (n = 188) including frontotemporal lobar degeneration with TDP-43 inclusions and amyotrophic lateral sclerosis; and a minimal pathology group (n = 72)...
June 5, 2018: Brain: a Journal of Neurology
Nicole R Karcher, Deanna M Barch, Shelli Avenevoli, Mark Savill, Rebekah S Huber, Tony J Simon, Ingrid N Leckliter, Kenneth J Sher, Rachel L Loewy
Importance: Childhood psychoticlike experiences (PLEs) are associated with greater odds of a diagnosis of a psychotic disorder during adulthood. However, no known, well-validated self-report tools have been designed to measure childhood PLEs. Objective: To examine the construct validity and psychometric properties of a measure of PLEs, the Prodromal Questionnaire-Brief Child Version (PQ-BC). Design, Setting, and Participants: This validation study used data from the first wave of the Adolescent Brain and Cognitive Development (ABCD) Study, a prospective longitudinal study aimed at assessing risk factors associated with adverse physical and mental health outcomes from ages 9 to 10 years into late adolescence and early adulthood...
June 6, 2018: JAMA Psychiatry
Tara M Brinkman, Christopher J Recklitis, Gisela Michel, Martha A Grootenhuis, James L Klosky
The diagnosis, treatment, and medical late effects of childhood cancer may alter the psychosocial trajectory of survivors across their life course. This review of the literature focuses on mental health symptoms, achievement of social milestones, socioeconomic attainment, and risky health behaviors in survivors of childhood cancer. Results suggest that although most survivors are psychologically well adjusted, survivors are at risk for anxiety and depression compared with siblings. Although the absolute risk of suicide ideation and post-traumatic stress symptoms is low, adult survivors are at increased risk compared with controls...
June 6, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
Onur Topoğlu, Derya Karagülle, Tuba U Keskin, Filiz Abacigil, Pinar Okyay
AIMS: This study assessed the general health, music performance anxiety (MPA), and coping methods of musicians working in six state orchestras in Turkey. METHODS: All musicians working in the state symphony orchestras (n=384) were invited to participate in the study. In face-to-face interviews, the authors administered a questionnaire, which consisted of five sections: sociodemographic information, history of musical performance, health status, general health questionnaire-12 (GHQ-12), and MPA scale...
June 2018: Medical Problems of Performing Artists
Vlatka Boričević Maršanić, Josipa Jukić, Mia Flander
The onset of psychosis is typically preceded by a prodromal phase that is characterised by the emergence of "attenuated" psychotic symptoms. This phase is described as ultra-high risk (UHR) or at-risk mental state (ARMS) of psychosis. Criteria have been established for identifying these young people who are at clinical high risk. People at ultra-high risk (UHR) of psychosis have about 30% chance of developing the illness within two years. This category was introduced with the goal of developing treatments for prevention of psychotic disorders...
June 2018: Psychiatria Danubina
Hossein Tabatabaei-Jafari, Erin Walsh, Marnie E Shaw, Nicolas Cherbuin
The current challenge in clinical practice is to identify those with mild cognitive impairment (MCI), who are at greater risk of Alzheimer's disease (AD) conversion in the near future. The aim of this study was to assess a clinically practical new hippocampal index-hippocampal volume normalized by cerebellar volume (hippocampus to cerebellum volume ratio) used alone or in combination with scores on the Mini-Mental State Examination, as a predictor of conversion from MCI to AD. The predictive value of the HCCR was also contrasted to that of the hippocampal volume to intracranial volume ratio...
June 1, 2018: Neurobiology of Aging
Katie Bechman, Fang En Sin, Fowzia Ibrahim, Sam Norton, Faith Matcham, David Lloyd Scott, Andrew Cope, James Galloway
Background: Tapering of anti-tumour necrosis factor (TNF) therapy appears feasible, safe and effective in selected patients with rheumatoid arthritis (RA). Depression is highly prevalent in RA and may impact on flare incidence through various mechanisms. This study aims to investigate if psychological states predict flare in patients' dose tapering their anti-TNF therapy. Methods: This study is a post-hoc analysis of the Optimizing TNF Tapering in RA trial, a multicentre, randomised, open-label study investigating anti-TNF tapering in RA patients with sustained low disease activity...
2018: RMD Open
Jessica A Hartmann, Barnaby Nelson, Aswin Ratheesh, Devi Treen, Patrick D McGorry
Identifying young people at risk of developing serious mental illness and identifying predictors of onset of illness has been a focus of psychiatric prediction research, particularly in the field of psychosis. Work in this area has facilitated the adoption of the clinical staging model of early clinical phenotypes, ranging from at-risk mental states to chronic and severe mental illness. It has been a topic of debate if these staging models should be conceptualised as disorder-specific or transdiagnostic. In order to inform this debate and facilitate cross-diagnostic discourse, the present scoping review provides a broad overview of the body of literature of (a) longitudinal at-risk approaches and (b) identified antecedents of (homotypic) illness progression across three major mental disorders [psychosis, bipolar disorder (BD) and depression], and places these in the context of clinical staging...
June 4, 2018: Psychological Medicine
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